DD229125A5 - Verfahren zur herstellung von ether-vorwirkstoffen von entzuendungshemmenden oxicamen - Google Patents

Verfahren zur herstellung von ether-vorwirkstoffen von entzuendungshemmenden oxicamen Download PDF

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Publication number
DD229125A5
DD229125A5 DD84271297A DD27129784A DD229125A5 DD 229125 A5 DD229125 A5 DD 229125A5 DD 84271297 A DD84271297 A DD 84271297A DD 27129784 A DD27129784 A DD 27129784A DD 229125 A5 DD229125 A5 DD 229125A5
Authority
DD
German Democratic Republic
Prior art keywords
mmol
methyl
found
cdcl
pyridyl
Prior art date
Application number
DD84271297A
Other languages
German (de)
English (en)
Inventor
Anthony Marfat
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DD229125A5 publication Critical patent/DD229125A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD84271297A 1983-12-21 1984-12-20 Verfahren zur herstellung von ether-vorwirkstoffen von entzuendungshemmenden oxicamen DD229125A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56390283A 1983-12-21 1983-12-21
US06/606,113 US4551452A (en) 1983-12-21 1984-05-02 Anti-inflammatory 2-methyl-2H-1,2-benzo-(or -thieno-)thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor

Publications (1)

Publication Number Publication Date
DD229125A5 true DD229125A5 (de) 1985-10-30

Family

ID=27073413

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84271297A DD229125A5 (de) 1983-12-21 1984-12-20 Verfahren zur herstellung von ether-vorwirkstoffen von entzuendungshemmenden oxicamen

Country Status (26)

Country Link
US (1) US4551452A (es)
EP (1) EP0147177B1 (es)
KR (1) KR860002035B1 (es)
AU (1) AU552940B2 (es)
BG (1) BG47946A3 (es)
CA (1) CA1255302A (es)
DD (1) DD229125A5 (es)
DE (1) DE3466776D1 (es)
DK (1) DK166678B1 (es)
EG (1) EG17049A (es)
ES (1) ES8604215A1 (es)
FI (1) FI79850C (es)
GR (1) GR82512B (es)
HK (1) HK58589A (es)
HU (1) HU201063B (es)
IE (1) IE57680B1 (es)
IL (1) IL73873A (es)
MX (2) MX174596B (es)
NO (1) NO161317C (es)
NZ (1) NZ210632A (es)
PH (1) PH21447A (es)
PL (1) PL145989B1 (es)
PT (1) PT79700B (es)
RO (1) RO90048A (es)
SG (1) SG27001G (es)
YU (1) YU43677B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4616012A (en) * 1983-11-25 1986-10-07 Schering Corporation Carboxyalkyl dipeptides as antiglaucoma agents
US4778795A (en) * 1983-11-25 1988-10-18 Schering Corporation Carboxyalkyl dipeptides as antiglaucoma agents
US4906635A (en) * 1983-11-25 1990-03-06 Schering Corporation Carboxyalkyl dipeptides as antiglaucoma agents
US5017567A (en) * 1983-11-25 1991-05-21 Schering Corporation Carboxyalkyl dipeptides as antiglaucoma agents
US4623486A (en) * 1985-05-29 1986-11-18 Pfizer Inc. [4-substituted benzoyloxy]-N-substituted-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity
KR890001236B1 (ko) * 1985-10-02 1989-04-28 화이자 인코포레이티드 소염제 조성물의 제조방법
US4771071A (en) * 1986-05-05 1988-09-13 Merck & Co., Inc. Antihypercholesterolemic compounds
WO1987006933A1 (en) * 1986-05-16 1987-11-19 Pfizer Inc. Benzothiazine dioxide derivatives
WO1989003682A1 (en) * 1987-10-26 1989-05-05 Pfizer Inc. Benzothiazine dioxide derivatives
IL87951A (en) * 1987-10-29 1992-03-29 Chem Pharm Forsch Gmbh Carbonic acid esters of 6-chloro-4-(1-hydroxyethoxy)-2-methyl-n-(2-pyridyl)-2h-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide,their preparation and pharmaceutical compositions containing them
ZA945190B (en) * 1993-07-30 1995-02-24 Kotobuki Seiyaku Co Ltd Carboxymethylidenecycloheptimidazole derivatives method or manufacturing the same and therapeutic agents containing these compounds
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
CN100389114C (zh) * 2006-01-17 2008-05-21 南京新港医药有限公司 一种安吡昔康的精制方法
US20090238763A1 (en) * 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
JP5378221B2 (ja) * 2006-10-11 2013-12-25 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するオキシカム及び関連化合物の正荷電水溶性プロドラッグ
KR101853971B1 (ko) 2007-06-04 2018-05-02 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도
RU2765463C2 (ru) 2008-12-04 2022-01-31 Чунси ЮЙ Композиции интенсивного проникновения и их применение
WO2013093931A2 (en) 2011-09-19 2013-06-27 Sun Pharma Advanced Research Company Ltd. Novel prodrugs of phenolic drugs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US3892740A (en) * 1974-10-15 1975-07-01 Pfizer Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
US4309427A (en) * 1981-01-15 1982-01-05 Pfizer Inc. Benzothiazine dioxide derivatives
IT1168064B (it) * 1981-11-12 1987-05-20 Prodotti Antibiotici Spa Composto ad azione antinfiammatoria
IT8219486A0 (it) * 1982-02-05 1982-02-05 Chiesi Farma Spa Nuovi composti ad attivita'antiinfiammatoria, procedimento per la loro preparazione e relative composizioni farmaceutiche.

Also Published As

Publication number Publication date
PT79700B (en) 1986-12-30
PH21447A (en) 1987-10-28
IE57680B1 (en) 1993-02-24
PL145989B1 (en) 1988-12-31
AU552940B2 (en) 1986-06-26
MX9203740A (es) 1992-09-01
IL73873A0 (en) 1985-03-31
NO161317C (no) 1989-08-02
KR860002035B1 (ko) 1986-11-17
FI79850C (fi) 1990-03-12
ES538907A0 (es) 1986-01-16
PL251040A1 (en) 1985-10-22
DK614984D0 (da) 1984-12-20
YU43677B (en) 1989-10-31
FI845074L (fi) 1985-06-22
EP0147177A3 (en) 1985-08-14
DK166678B1 (da) 1993-06-28
KR850004492A (ko) 1985-07-15
MX174596B (es) 1994-05-30
IL73873A (en) 1988-02-29
EG17049A (en) 1991-03-30
US4551452A (en) 1985-11-05
PT79700A (en) 1985-01-01
GR82512B (en) 1985-04-22
SG27001G (en) 1989-08-11
HU201063B (en) 1990-09-28
DE3466776D1 (en) 1987-11-19
NO161317B (no) 1989-04-24
RO90048A (ro) 1986-09-30
IE843260L (en) 1985-06-21
FI79850B (fi) 1989-11-30
CA1255302A (en) 1989-06-06
DK614984A (da) 1985-07-17
YU216084A (en) 1986-10-31
AU3699784A (en) 1985-07-04
ES8604215A1 (es) 1986-01-16
HUT37426A (en) 1985-12-28
NO845145L (no) 1985-06-24
FI845074A0 (fi) 1984-12-20
BG47946A3 (en) 1990-10-15
EP0147177A2 (en) 1985-07-03
NZ210632A (en) 1987-02-20
EP0147177B1 (en) 1987-10-14
HK58589A (en) 1989-07-28

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Legal Events

Date Code Title Description
NPV Change in the person, the name or the address of the representative (addendum to changes before extension act)
ENJ Ceased due to non-payment of renewal fee