DD222305A5 - Verfahren zur herstellung von 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile - Google Patents

Verfahren zur herstellung von 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile Download PDF

Info

Publication number
DD222305A5
DD222305A5 DD84262957A DD26295784A DD222305A5 DD 222305 A5 DD222305 A5 DD 222305A5 DD 84262957 A DD84262957 A DD 84262957A DD 26295784 A DD26295784 A DD 26295784A DD 222305 A5 DD222305 A5 DD 222305A5
Authority
DD
German Democratic Republic
Prior art keywords
pyrroline
carbonitrile
oxo
general formula
animals
Prior art date
Application number
DD84262957A
Other languages
German (de)
English (en)
Inventor
Hubert Barth
Johannes Hartenstein
Gerhard Satzinger
Edgar Fritschi
Volker Ganser
Horst-Dietmar Tauschel
Guenter Wolf
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of DD222305A5 publication Critical patent/DD222305A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DD84262957A 1983-05-14 1984-05-11 Verfahren zur herstellung von 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile DD222305A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833317653 DE3317653A1 (de) 1983-05-14 1983-05-14 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende

Publications (1)

Publication Number Publication Date
DD222305A5 true DD222305A5 (de) 1985-05-15

Family

ID=6199021

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84262957A DD222305A5 (de) 1983-05-14 1984-05-11 Verfahren zur herstellung von 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile

Country Status (15)

Country Link
US (1) US4499089A (fr)
EP (1) EP0125684B1 (fr)
JP (1) JPS59212469A (fr)
AT (1) ATE28189T1 (fr)
AU (1) AU2798884A (fr)
CS (1) CS244815B2 (fr)
DD (1) DD222305A5 (fr)
DE (2) DE3317653A1 (fr)
DK (1) DK239084A (fr)
ES (3) ES8502867A1 (fr)
GR (1) GR82094B (fr)
HU (1) HUT34158A (fr)
SU (1) SU1251800A3 (fr)
YU (1) YU83284A (fr)
ZA (1) ZA843615B (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL176372B (nl) * 1952-02-26 Salvat Editores Werkwijze voor het bereiden van drukinkt alsmede werkwijze voor het bereiden van een preparaat om aan drukinkt te worden toegevoegd.
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin
NZ182264A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions
US4329347A (en) * 1978-02-17 1982-05-11 Boehringer Ingelheim Gmbh Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
DK75779A (da) * 1978-03-13 1979-09-14 Du Pont 4,5-diaryl-2- (substitueret thio) pyrroler og sulfoxider og sulfoner deraf samt fremgangsmaader til deres fremstilling og anvendelse
DE3212591A1 (de) * 1982-04-03 1983-10-13 Gödecke AG, 1000 Berlin 2-pyrrolin-3-carbonitril-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3317653A1 (de) 1984-11-15
GR82094B (fr) 1984-12-13
ATE28189T1 (de) 1987-07-15
ES532438A0 (es) 1985-02-01
DE3464601D1 (en) 1987-08-13
YU83284A (en) 1986-10-31
SU1251800A3 (ru) 1986-08-15
CS330884A2 (en) 1985-09-17
ES532446A0 (es) 1985-01-01
ES8502867A1 (es) 1985-02-01
ES8502421A1 (es) 1985-01-01
CS244815B2 (en) 1986-08-14
AU2798884A (en) 1984-11-15
ES532445A0 (es) 1985-02-01
ZA843615B (en) 1984-12-24
EP0125684B1 (fr) 1987-07-08
DK239084A (da) 1984-11-15
DK239084D0 (da) 1984-05-14
HUT34158A (en) 1985-02-28
EP0125684A1 (fr) 1984-11-21
US4499089A (en) 1985-02-12
JPS59212469A (ja) 1984-12-01
ES8502868A1 (es) 1985-02-01

Similar Documents

Publication Publication Date Title
DE69813815T2 (de) Hydrazinderivate
DE69128145T2 (de) 1,2,5,6-tetrahydro-1-methylpyridine, ihre herstellung und anwendung
DE2238504C3 (de) l-Phenoxy-S-alkylaminopropan^-ol -Derivate
EP0072932A2 (fr) Pipérazinones, leur préparation et leur utilisation
EP0058975B1 (fr) N-(4-Indolyl-pipéridino-alkyl)-benzimidazolones substituées, procédés pour leur préparation et leur utilisation en thérapeutique
DE1670536B2 (de) Neue 2-Anilino-5-acylamino-pyrimidlne
EP0000220B1 (fr) Dihydrouraciles, procédé pour leur préparation et médicaments les contenant
DE69027180T2 (de) 4-Acylaminopyridin-Derivate
DE2166381C3 (de) γ-Piperidinobutyrophenonderivate, Verfahren zu i hrer Herstellung und Arzneipräparate
DE2012138A1 (de) Neue Pyrazinderivate und diese enthaltende pharmazeutische Präparate
DE2847792C2 (fr)
DD201903A5 (de) Verfahren zur herstellung von derivaten des thienopyridonons
DE68912263T2 (de) 4-Methyl-5[2-(4-phenyl-1-piperazinyl)-ethyl]-Thiazolderivate, ihre Herstellung und Zusammenstellungen, die sie enthalten.
EP0261478A1 (fr) Dérivés de 4,5 dihydro-oxazoles, procédé de leur préparation et leur application
DE2617955A1 (de) Neue l-substituierte -aroyl-4-hydroxypiperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE69826881T2 (de) Neue indolcarboxamide, pharmazeutische zusammensetzungen und methoden zur hemmung von calpain
DD222305A5 (de) Verfahren zur herstellung von 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile
DE2513136C3 (de) N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
EP0091045B1 (fr) Dérivés de 2-pyrrolin-3-carbonitrile, procédé de préparation et médicaments les contenant
DE2245061A1 (de) Derivate des adenins
DE2757766A1 (de) 1-substituierte-3-aminoaethoxypyrrolidine, ihre herstellung und verwendung als blutdrucksenkendes mittel
DE2912026C2 (fr)
DE2340217C2 (de) 3-Benzoylthiophene, ihre Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0326981A2 (fr) Dérivés de 4-oxo-4H-pyrido[1,2-a]pyrimidine 3-carboxamide, leur préparation, médicaments les contenant et leur préparation
CH634315A5 (de) Verfahren zur herstellung von substituierten 2-vinylchromonen.