CS244815B2 - Production method of 2-alkylthio-1-aminoalkyl-5-oxo-2-pycarbonitrilles - Google Patents
Production method of 2-alkylthio-1-aminoalkyl-5-oxo-2-pycarbonitrilles Download PDFInfo
- Publication number
- CS244815B2 CS244815B2 CS843308A CS330884A CS244815B2 CS 244815 B2 CS244815 B2 CS 244815B2 CS 843308 A CS843308 A CS 843308A CS 330884 A CS330884 A CS 330884A CS 244815 B2 CS244815 B2 CS 244815B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- oxo
- solvent
- pyrroline
- animals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833317653 DE3317653A1 (de) | 1983-05-14 | 1983-05-14 | 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS330884A2 CS330884A2 (en) | 1985-09-17 |
| CS244815B2 true CS244815B2 (en) | 1986-08-14 |
Family
ID=6199021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS843308A CS244815B2 (en) | 1983-05-14 | 1984-05-04 | Production method of 2-alkylthio-1-aminoalkyl-5-oxo-2-pycarbonitrilles |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4499089A (fr) |
| EP (1) | EP0125684B1 (fr) |
| JP (1) | JPS59212469A (fr) |
| AT (1) | ATE28189T1 (fr) |
| AU (1) | AU2798884A (fr) |
| CS (1) | CS244815B2 (fr) |
| DD (1) | DD222305A5 (fr) |
| DE (2) | DE3317653A1 (fr) |
| DK (1) | DK239084A (fr) |
| ES (3) | ES532446A0 (fr) |
| GR (1) | GR82094B (fr) |
| HU (1) | HUT34158A (fr) |
| SU (1) | SU1251800A3 (fr) |
| YU (1) | YU83284A (fr) |
| ZA (1) | ZA843615B (fr) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL176372B (nl) * | 1952-02-26 | Salvat Editores | Werkwijze voor het bereiden van drukinkt alsmede werkwijze voor het bereiden van een preparaat om aan drukinkt te worden toegevoegd. | |
| FI59246C (fi) * | 1974-06-24 | 1981-07-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin |
| NZ182264A (en) * | 1975-10-25 | 1979-01-11 | Beecham Group Ltd | 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions |
| US4329347A (en) * | 1978-02-17 | 1982-05-11 | Boehringer Ingelheim Gmbh | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril |
| DK75779A (da) * | 1978-03-13 | 1979-09-14 | Du Pont | 4,5-diaryl-2- (substitueret thio) pyrroler og sulfoxider og sulfoner deraf samt fremgangsmaader til deres fremstilling og anvendelse |
| DE3212591A1 (de) * | 1982-04-03 | 1983-10-13 | Gödecke AG, 1000 Berlin | 2-pyrrolin-3-carbonitril-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
-
1983
- 1983-05-14 DE DE19833317653 patent/DE3317653A1/de not_active Ceased
-
1984
- 1984-05-04 CS CS843308A patent/CS244815B2/cs unknown
- 1984-05-10 GR GR74677A patent/GR82094B/el unknown
- 1984-05-10 US US06/608,828 patent/US4499089A/en not_active Expired - Fee Related
- 1984-05-11 YU YU00832/84A patent/YU83284A/xx unknown
- 1984-05-11 DD DD84262957A patent/DD222305A5/de unknown
- 1984-05-11 JP JP59093126A patent/JPS59212469A/ja active Pending
- 1984-05-11 ES ES532446A patent/ES532446A0/es active Granted
- 1984-05-11 SU SU843737938A patent/SU1251800A3/ru active
- 1984-05-11 HU HU841851A patent/HUT34158A/hu unknown
- 1984-05-11 ES ES532445A patent/ES8502868A1/es not_active Expired
- 1984-05-11 ES ES532438A patent/ES532438A0/es active Granted
- 1984-05-14 ZA ZA843615A patent/ZA843615B/xx unknown
- 1984-05-14 DK DK239084A patent/DK239084A/da not_active Application Discontinuation
- 1984-05-14 AU AU27988/84A patent/AU2798884A/en not_active Abandoned
- 1984-05-14 AT AT84105457T patent/ATE28189T1/de not_active IP Right Cessation
- 1984-05-14 DE DE8484105457T patent/DE3464601D1/de not_active Expired
- 1984-05-14 EP EP84105457A patent/EP0125684B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK239084D0 (da) | 1984-05-14 |
| JPS59212469A (ja) | 1984-12-01 |
| ES8502421A1 (es) | 1985-01-01 |
| DK239084A (da) | 1984-11-15 |
| ES532445A0 (es) | 1985-02-01 |
| HUT34158A (en) | 1985-02-28 |
| YU83284A (en) | 1986-10-31 |
| SU1251800A3 (ru) | 1986-08-15 |
| CS330884A2 (en) | 1985-09-17 |
| AU2798884A (en) | 1984-11-15 |
| DD222305A5 (de) | 1985-05-15 |
| ES8502867A1 (es) | 1985-02-01 |
| ES532438A0 (es) | 1985-02-01 |
| ES532446A0 (es) | 1985-01-01 |
| EP0125684B1 (fr) | 1987-07-08 |
| EP0125684A1 (fr) | 1984-11-21 |
| ZA843615B (en) | 1984-12-24 |
| GR82094B (fr) | 1984-12-13 |
| ES8502868A1 (es) | 1985-02-01 |
| ATE28189T1 (de) | 1987-07-15 |
| DE3317653A1 (de) | 1984-11-15 |
| US4499089A (en) | 1985-02-12 |
| DE3464601D1 (en) | 1987-08-13 |
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