DD209624A5 - Verfahren zur herstellung von benzimidazolverbindungen - Google Patents
Verfahren zur herstellung von benzimidazolverbindungen Download PDFInfo
- Publication number
- DD209624A5 DD209624A5 DD83249690A DD24969083A DD209624A5 DD 209624 A5 DD209624 A5 DD 209624A5 DD 83249690 A DD83249690 A DD 83249690A DD 24969083 A DD24969083 A DD 24969083A DD 209624 A5 DD209624 A5 DD 209624A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- benzimidazole
- amino
- formula
- compounds
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/366,760 US4420479A (en) | 1982-04-08 | 1982-04-08 | Olefinic benzimidazoles, formulations, and antiviral methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD209624A5 true DD209624A5 (de) | 1984-05-16 |
Family
ID=23444387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD83249690A DD209624A5 (de) | 1982-04-08 | 1983-04-08 | Verfahren zur herstellung von benzimidazolverbindungen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4420479A (enExample) |
| EP (1) | EP0091795A1 (enExample) |
| KR (1) | KR840004409A (enExample) |
| AU (1) | AU1322483A (enExample) |
| CA (1) | CA1197245A (enExample) |
| DD (1) | DD209624A5 (enExample) |
| DK (1) | DK152883A (enExample) |
| ES (2) | ES8502097A1 (enExample) |
| FI (1) | FI831191L (enExample) |
| GB (1) | GB2119789B (enExample) |
| GR (1) | GR78168B (enExample) |
| IL (1) | IL68299A0 (enExample) |
| NZ (1) | NZ203798A (enExample) |
| PH (1) | PH18108A (enExample) |
| PL (3) | PL241385A1 (enExample) |
| PT (1) | PT76499B (enExample) |
| RO (1) | RO86319B (enExample) |
| ZA (1) | ZA832410B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2092539T3 (es) * | 1991-01-10 | 1996-12-01 | Transcend Therapeutics Inc | Uso de derivados de la tiazolidina-4-carboxilato para el tratamiento de enfermedades pulmonares. |
| US5747459A (en) * | 1991-02-04 | 1998-05-05 | Nestec, Ltd. | Method for insuring adequate intracellular glutathione in tissue |
| US5430045A (en) * | 1992-04-23 | 1995-07-04 | Free Radical Sciences, Inc. | Method of reducing or preventing bone marrow hypoplasia |
| JP2787539B2 (ja) * | 1993-02-26 | 1998-08-20 | 松森 昭 | ウイルス性疾患の予防または治療剤 |
| US5447712A (en) * | 1993-12-09 | 1995-09-05 | Free Radical Sciences | Method of reducing cyclophosphamide induced hemorrhagic cystitis |
| US5475109A (en) * | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
| US5693661A (en) * | 1995-06-07 | 1997-12-02 | Eli Lilly And Company | Anti-viral compounds |
| US5545653A (en) * | 1995-06-07 | 1996-08-13 | Eli Lilly And Company | Anti-viral compounds |
| US5891874A (en) * | 1996-06-05 | 1999-04-06 | Eli Lilly And Company | Anti-viral compound |
| EA001316B1 (ru) * | 1996-06-05 | 2001-02-26 | Эли Лилли Энд Компании | Соединения, обладающие антивирусной активностью |
| US5821242A (en) * | 1996-06-06 | 1998-10-13 | Eli Lilly And Company | Anti-viral compounds |
| ES2315435T3 (es) | 1996-08-12 | 2009-04-01 | Celgene Corporation | Nuevos agentes inmunoterapeuticos y su uso para la reduccion de los niveles de citoquinas. |
| WO1998031363A1 (en) * | 1997-01-22 | 1998-07-23 | Eli Lilly And Company | Anti-viral compounds |
| CA2293508A1 (en) * | 1997-06-04 | 1998-12-10 | Louis Nickolaus Jungheim | Anti-viral compounds |
| ZA200507321B (en) | 2003-03-05 | 2007-03-28 | Celgene Corp | Diphenylethylene compounds and uses thereof |
| US7470723B2 (en) | 2003-03-05 | 2008-12-30 | Celgene Corporation | Diphenylethylene compounds and uses thereof |
| BRPI0514857A (pt) | 2004-09-03 | 2008-05-06 | Celgene Corp | composto ou um sal, solvato ou hidrato farmaceuticamente aceitável do mesmo, composição farmacêutica, e, métodos para inibir a angiogênese, para inibir ou reduzir a polimerização da tubulina ou a estabilidade da tubulina em uma célula, para inibir a atividade de pde4 em uma célula, para inibir atividade do fator-alfa de necrose de tumor (tnf-alfa) em uma célula, para tratar ou melhorar um distúrbio inflamatório, para tratar ou melhorar cáncer, para inibir a proliferação de célula cancerosa, para marcar, bloquear ou destruir a função de vasculatura tumoral, para marcar, bloquear ou destruir o endotélio de vasos tumor, para marcar, bloquear ou destruir a função de vasculatura tumoral e inibir a angiogênese em um tumor e para tratar ou melhorar um distúrbio do sistema nervoso central |
| CN108997158B (zh) * | 2018-07-16 | 2020-12-15 | 青岛科技大学 | 一种实现二取代酰胺与二苯基甲酮偶联的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4018790A (en) * | 1975-05-08 | 1977-04-19 | Eli Lilly And Company | Substituted 1-sulfonylbenzimidazoles |
| PT65486B (en) * | 1975-08-28 | 1978-03-24 | Lilly Co Eli | Process for the preparation of carbonil-substituted 1-sulfonylbenzimidazoles |
| US4174454A (en) * | 1975-08-28 | 1979-11-13 | Eli Lilly And Company | Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles |
| CA1076582A (en) * | 1975-10-28 | 1980-04-29 | Charles J. Paget | Antiviral thiazolinyl or thiazinyl ketobenzimidazoles |
| US4008243A (en) * | 1975-11-19 | 1977-02-15 | Eli Lilly And Company | Antiviral thiazolinyl or thiazinyl benzimidazole esters |
| US4118573A (en) * | 1975-11-24 | 1978-10-03 | Eli Lilly And Company | Substituted 1-sulfonylbenzimidazoles |
| GR66420B (enExample) * | 1976-12-15 | 1981-03-20 | Lilly Co Eli | |
| US4230868A (en) * | 1979-04-17 | 1980-10-28 | Eli Lilly And Company | α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles |
| US4316021A (en) * | 1979-08-13 | 1982-02-16 | Eli Lilly And Company | Substituted 1-sulfonylbenzimidazoles |
-
1982
- 1982-04-08 US US06/366,760 patent/US4420479A/en not_active Expired - Lifetime
-
1983
- 1983-04-05 PH PH28738A patent/PH18108A/en unknown
- 1983-04-05 ZA ZA832410A patent/ZA832410B/xx unknown
- 1983-04-05 PT PT76499A patent/PT76499B/pt unknown
- 1983-04-05 IL IL68299A patent/IL68299A0/xx unknown
- 1983-04-06 RO RO110574A patent/RO86319B/ro unknown
- 1983-04-06 GR GR71005A patent/GR78168B/el unknown
- 1983-04-06 CA CA000425307A patent/CA1197245A/en not_active Expired
- 1983-04-06 NZ NZ203798A patent/NZ203798A/en unknown
- 1983-04-06 KR KR1019830001417A patent/KR840004409A/ko not_active Ceased
- 1983-04-06 DK DK152883A patent/DK152883A/da not_active IP Right Cessation
- 1983-04-07 PL PL24138583A patent/PL241385A1/xx unknown
- 1983-04-07 GB GB08309388A patent/GB2119789B/en not_active Expired
- 1983-04-07 PL PL24790883A patent/PL247908A1/xx unknown
- 1983-04-07 ES ES521318A patent/ES8502097A1/es not_active Expired
- 1983-04-07 EP EP83301976A patent/EP0091795A1/en not_active Ceased
- 1983-04-07 AU AU13224/83A patent/AU1322483A/en not_active Abandoned
- 1983-04-07 PL PL24790983A patent/PL247909A1/xx unknown
- 1983-04-08 DD DD83249690A patent/DD209624A5/de unknown
- 1983-04-08 FI FI831191A patent/FI831191L/fi not_active Application Discontinuation
-
1984
- 1984-07-11 ES ES534218A patent/ES534218A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NZ203798A (en) | 1985-07-12 |
| PT76499B (en) | 1986-03-18 |
| EP0091795A1 (en) | 1983-10-19 |
| GB2119789B (en) | 1985-08-29 |
| IL68299A0 (en) | 1983-07-31 |
| FI831191A0 (fi) | 1983-04-08 |
| FI831191A7 (fi) | 1983-10-09 |
| ES521318A0 (es) | 1984-12-16 |
| KR840004409A (ko) | 1984-10-15 |
| PL241385A1 (en) | 1984-09-24 |
| PT76499A (en) | 1983-05-01 |
| RO86319B (ro) | 1985-03-31 |
| AU1322483A (en) | 1983-10-13 |
| DK152883A (da) | 1983-10-09 |
| US4420479A (en) | 1983-12-13 |
| ES8505966A1 (es) | 1985-06-01 |
| PL247908A1 (en) | 1985-01-16 |
| FI831191L (fi) | 1983-10-09 |
| RO86319A (ro) | 1985-03-15 |
| GR78168B (enExample) | 1984-09-26 |
| ZA832410B (en) | 1984-11-28 |
| DK152883D0 (da) | 1983-04-06 |
| PH18108A (en) | 1985-03-22 |
| ES8502097A1 (es) | 1984-12-16 |
| GB2119789A (en) | 1983-11-23 |
| PL247909A1 (en) | 1984-12-17 |
| ES534218A0 (es) | 1985-06-01 |
| CA1197245A (en) | 1985-11-26 |
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