ES534218A0 - Un procedimiento para la preparacion de compuestos de bencimidazol - Google Patents
Un procedimiento para la preparacion de compuestos de bencimidazolInfo
- Publication number
- ES534218A0 ES534218A0 ES534218A ES534218A ES534218A0 ES 534218 A0 ES534218 A0 ES 534218A0 ES 534218 A ES534218 A ES 534218A ES 534218 A ES534218 A ES 534218A ES 534218 A0 ES534218 A0 ES 534218A0
- Authority
- ES
- Spain
- Prior art keywords
- benzmidazole
- compounds
- procedure
- preparation
- benzmidazole compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/366,760 US4420479A (en) | 1982-04-08 | 1982-04-08 | Olefinic benzimidazoles, formulations, and antiviral methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8505966A1 ES8505966A1 (es) | 1985-06-01 |
| ES534218A0 true ES534218A0 (es) | 1985-06-01 |
Family
ID=23444387
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521318A Granted ES521318A0 (es) | 1982-04-08 | 1983-04-07 | Un procedimiento para la preparacion de compuestos de bencimidazol. |
| ES534218A Granted ES534218A0 (es) | 1982-04-08 | 1984-07-11 | Un procedimiento para la preparacion de compuestos de bencimidazol |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521318A Granted ES521318A0 (es) | 1982-04-08 | 1983-04-07 | Un procedimiento para la preparacion de compuestos de bencimidazol. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4420479A (es) |
| EP (1) | EP0091795A1 (es) |
| KR (1) | KR840004409A (es) |
| AU (1) | AU1322483A (es) |
| CA (1) | CA1197245A (es) |
| DD (1) | DD209624A5 (es) |
| DK (1) | DK152883A (es) |
| ES (2) | ES521318A0 (es) |
| FI (1) | FI831191L (es) |
| GB (1) | GB2119789B (es) |
| GR (1) | GR78168B (es) |
| IL (1) | IL68299A0 (es) |
| NZ (1) | NZ203798A (es) |
| PH (1) | PH18108A (es) |
| PL (3) | PL247908A1 (es) |
| PT (1) | PT76499B (es) |
| RO (1) | RO86319B (es) |
| ZA (1) | ZA832410B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE144142T1 (de) * | 1991-01-10 | 1996-11-15 | Transcend Therapeutics Inc | Verwendung von thiazolidin-4-carboxylatderivaten zur behandlung von lungenerkrankungen |
| US5747459A (en) * | 1991-02-04 | 1998-05-05 | Nestec, Ltd. | Method for insuring adequate intracellular glutathione in tissue |
| US5430045A (en) * | 1992-04-23 | 1995-07-04 | Free Radical Sciences, Inc. | Method of reducing or preventing bone marrow hypoplasia |
| JP2787539B2 (ja) * | 1993-02-26 | 1998-08-20 | 松森 昭 | ウイルス性疾患の予防または治療剤 |
| US5447712A (en) * | 1993-12-09 | 1995-09-05 | Free Radical Sciences | Method of reducing cyclophosphamide induced hemorrhagic cystitis |
| US5475109A (en) * | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
| US5693661A (en) * | 1995-06-07 | 1997-12-02 | Eli Lilly And Company | Anti-viral compounds |
| US5545653A (en) * | 1995-06-07 | 1996-08-13 | Eli Lilly And Company | Anti-viral compounds |
| CN1220601A (zh) * | 1996-06-05 | 1999-06-23 | 伊莱利利公司 | 抗病毒化合物 |
| US5891874A (en) * | 1996-06-05 | 1999-04-06 | Eli Lilly And Company | Anti-viral compound |
| US5821242A (en) * | 1996-06-06 | 1998-10-13 | Eli Lilly And Company | Anti-viral compounds |
| KR100539030B1 (ko) | 1996-08-12 | 2005-12-27 | 셀진 코포레이션 | 면역치료제 및 이를 이용하여 사이토카인 농도를 감소시키는 방법 |
| WO1998031363A1 (en) * | 1997-01-22 | 1998-07-23 | Eli Lilly And Company | Anti-viral compounds |
| AU7715198A (en) * | 1997-06-04 | 1998-12-21 | Eli Lilly And Company | Anti-viral compounds |
| US7470723B2 (en) | 2003-03-05 | 2008-12-30 | Celgene Corporation | Diphenylethylene compounds and uses thereof |
| BRPI0408005A (pt) | 2003-03-05 | 2006-02-14 | Celgene Corp | composto, composição farmacêutica, métodos para inibir angiogênese, atividade de pde4 em uma célula e proliferação de célula de cáncer, para inibir ou reduzir polimerização de tubulina ou estabilidade de tubulina em uma célula, para tratar ou melhorar um distúrbio inflamatório, um cáncer e um distúrbio do sistema nervoso central e para visar, bloquear ou destruir a função de vasculatura de tumor e o endotélio de vasos de tumor |
| BRPI0514857A (pt) | 2004-09-03 | 2008-05-06 | Celgene Corp | composto ou um sal, solvato ou hidrato farmaceuticamente aceitável do mesmo, composição farmacêutica, e, métodos para inibir a angiogênese, para inibir ou reduzir a polimerização da tubulina ou a estabilidade da tubulina em uma célula, para inibir a atividade de pde4 em uma célula, para inibir atividade do fator-alfa de necrose de tumor (tnf-alfa) em uma célula, para tratar ou melhorar um distúrbio inflamatório, para tratar ou melhorar cáncer, para inibir a proliferação de célula cancerosa, para marcar, bloquear ou destruir a função de vasculatura tumoral, para marcar, bloquear ou destruir o endotélio de vasos tumor, para marcar, bloquear ou destruir a função de vasculatura tumoral e inibir a angiogênese em um tumor e para tratar ou melhorar um distúrbio do sistema nervoso central |
| CN108997158B (zh) * | 2018-07-16 | 2020-12-15 | 青岛科技大学 | 一种实现二取代酰胺与二苯基甲酮偶联的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4018790A (en) * | 1975-05-08 | 1977-04-19 | Eli Lilly And Company | Substituted 1-sulfonylbenzimidazoles |
| GR61627B (en) * | 1975-08-28 | 1978-12-04 | Lilly Co Eli | Preparation process of carbonyl-substituted 1-sulfonylbenzimidazoles |
| US4174454A (en) * | 1975-08-28 | 1979-11-13 | Eli Lilly And Company | Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles |
| CA1076582A (en) * | 1975-10-28 | 1980-04-29 | Charles J. Paget | Antiviral thiazolinyl or thiazinyl ketobenzimidazoles |
| US4008243A (en) * | 1975-11-19 | 1977-02-15 | Eli Lilly And Company | Antiviral thiazolinyl or thiazinyl benzimidazole esters |
| US4118573A (en) * | 1975-11-24 | 1978-10-03 | Eli Lilly And Company | Substituted 1-sulfonylbenzimidazoles |
| GR66420B (es) * | 1976-12-15 | 1981-03-20 | Lilly Co Eli | |
| US4230868A (en) * | 1979-04-17 | 1980-10-28 | Eli Lilly And Company | α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles |
| US4316021A (en) * | 1979-08-13 | 1982-02-16 | Eli Lilly And Company | Substituted 1-sulfonylbenzimidazoles |
-
1982
- 1982-04-08 US US06/366,760 patent/US4420479A/en not_active Expired - Lifetime
-
1983
- 1983-04-05 ZA ZA832410A patent/ZA832410B/xx unknown
- 1983-04-05 IL IL68299A patent/IL68299A0/xx unknown
- 1983-04-05 PT PT76499A patent/PT76499B/pt unknown
- 1983-04-05 PH PH28738A patent/PH18108A/en unknown
- 1983-04-06 RO RO110574A patent/RO86319B/ro unknown
- 1983-04-06 CA CA000425307A patent/CA1197245A/en not_active Expired
- 1983-04-06 GR GR71005A patent/GR78168B/el unknown
- 1983-04-06 NZ NZ203798A patent/NZ203798A/en unknown
- 1983-04-06 KR KR1019830001417A patent/KR840004409A/ko not_active Application Discontinuation
- 1983-04-06 DK DK152883A patent/DK152883A/da not_active IP Right Cessation
- 1983-04-07 AU AU13224/83A patent/AU1322483A/en not_active Abandoned
- 1983-04-07 GB GB08309388A patent/GB2119789B/en not_active Expired
- 1983-04-07 PL PL24790883A patent/PL247908A1/xx unknown
- 1983-04-07 EP EP83301976A patent/EP0091795A1/en not_active Ceased
- 1983-04-07 PL PL24790983A patent/PL247909A1/xx unknown
- 1983-04-07 ES ES521318A patent/ES521318A0/es active Granted
- 1983-04-07 PL PL24138583A patent/PL241385A1/xx unknown
- 1983-04-08 DD DD83249690A patent/DD209624A5/de unknown
- 1983-04-08 FI FI831191A patent/FI831191L/fi not_active Application Discontinuation
-
1984
- 1984-07-11 ES ES534218A patent/ES534218A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB2119789A (en) | 1983-11-23 |
| AU1322483A (en) | 1983-10-13 |
| FI831191A0 (fi) | 1983-04-08 |
| PT76499B (en) | 1986-03-18 |
| CA1197245A (en) | 1985-11-26 |
| DD209624A5 (de) | 1984-05-16 |
| ZA832410B (en) | 1984-11-28 |
| FI831191L (fi) | 1983-10-09 |
| NZ203798A (en) | 1985-07-12 |
| RO86319A (ro) | 1985-03-15 |
| KR840004409A (ko) | 1984-10-15 |
| RO86319B (ro) | 1985-03-31 |
| DK152883A (da) | 1983-10-09 |
| ES8502097A1 (es) | 1984-12-16 |
| PH18108A (en) | 1985-03-22 |
| PL247908A1 (en) | 1985-01-16 |
| ES8505966A1 (es) | 1985-06-01 |
| GR78168B (es) | 1984-09-26 |
| DK152883D0 (da) | 1983-04-06 |
| US4420479A (en) | 1983-12-13 |
| PL241385A1 (en) | 1984-09-24 |
| IL68299A0 (en) | 1983-07-31 |
| ES521318A0 (es) | 1984-12-16 |
| PL247909A1 (en) | 1984-12-17 |
| EP0091795A1 (en) | 1983-10-19 |
| PT76499A (en) | 1983-05-01 |
| GB2119789B (en) | 1985-08-29 |
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