DD202559A5 - Verfahren zur herstellung von 4-oxo-pgi tief 2 und dessen analoge - Google Patents

Verfahren zur herstellung von 4-oxo-pgi tief 2 und dessen analoge Download PDF

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Publication number
DD202559A5
DD202559A5 DD82238986A DD23898682A DD202559A5 DD 202559 A5 DD202559 A5 DD 202559A5 DD 82238986 A DD82238986 A DD 82238986A DD 23898682 A DD23898682 A DD 23898682A DD 202559 A5 DD202559 A5 DD 202559A5
Authority
DD
German Democratic Republic
Prior art keywords
group
pgi
general formula
oxo
compounds
Prior art date
Application number
DD82238986A
Other languages
German (de)
English (en)
Inventor
Geza Galambos
Vilmos Simonidesz
Istvan Szekely
Jozsef Ivanics
Krisztina Kekesi
Gabor Kovacs
Istvan Stadler
Peter Koermoeczy
Karoly Horvath
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of DD202559A5 publication Critical patent/DD202559A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
DD82238986A 1981-04-14 1982-04-14 Verfahren zur herstellung von 4-oxo-pgi tief 2 und dessen analoge DD202559A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU81966A HU184949B (en) 1981-04-14 1981-04-14 Process for preparing 4-oxo-pgi down 2 and analogues thereof

Publications (1)

Publication Number Publication Date
DD202559A5 true DD202559A5 (de) 1983-09-21

Family

ID=10952245

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82238986A DD202559A5 (de) 1981-04-14 1982-04-14 Verfahren zur herstellung von 4-oxo-pgi tief 2 und dessen analoge

Country Status (14)

Country Link
US (1) US4438132A (hu)
EP (1) EP0063338B1 (hu)
JP (1) JPS57179178A (hu)
AT (1) ATA139182A (hu)
CS (1) CS228923B2 (hu)
DD (1) DD202559A5 (hu)
DE (1) DE3262285D1 (hu)
DK (1) DK165382A (hu)
FI (1) FI821282L (hu)
GR (1) GR76128B (hu)
HU (1) HU184949B (hu)
IL (1) IL65491A (hu)
PL (1) PL235963A1 (hu)
SU (1) SU1128834A3 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184948B (en) * 1981-04-14 1984-11-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 5-substituted 4-oxo-pgi down 1 derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126744A (en) * 1977-12-05 1978-11-21 The Upjohn Company 4-Oxo-PGI1 compounds
JPS54115368A (en) * 1978-03-01 1979-09-07 Ono Pharmaceut Co Ltd Prostaglandin i2 analog, its preparation, and drug composition containing it as active constituent

Also Published As

Publication number Publication date
FI821282A0 (fi) 1982-04-13
ATA139182A (de) 1986-03-15
HU184949B (en) 1984-11-28
DE3262285D1 (en) 1985-03-28
EP0063338A1 (de) 1982-10-27
DK165382A (da) 1982-10-15
IL65491A (en) 1986-01-31
CS228923B2 (en) 1984-05-14
IL65491A0 (en) 1982-07-30
FI821282L (fi) 1982-10-15
SU1128834A3 (ru) 1984-12-07
EP0063338B1 (de) 1985-02-13
JPS57179178A (en) 1982-11-04
GR76128B (hu) 1984-08-03
US4438132A (en) 1984-03-20
PL235963A1 (en) 1983-07-04

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