DD202018A5 - Verfahren zur herstellung von 3,1-benzoxazin-2-onen - Google Patents

Verfahren zur herstellung von 3,1-benzoxazin-2-onen Download PDF

Info

Publication number
DD202018A5
DD202018A5 DD81231670A DD23167081A DD202018A5 DD 202018 A5 DD202018 A5 DD 202018A5 DD 81231670 A DD81231670 A DD 81231670A DD 23167081 A DD23167081 A DD 23167081A DD 202018 A5 DD202018 A5 DD 202018A5
Authority
DD
German Democratic Republic
Prior art keywords
salt
hydrogen
alkyl
group
general formula
Prior art date
Application number
DD81231670A
Other languages
German (de)
English (en)
Inventor
Anton Mentrup
Kurt Schromm
Ernst-Otto Renth
Wolfgang Hoefke
Wolfram Gaida
Ilse Streller
Armin Fuegner
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of DD202018A5 publication Critical patent/DD202018A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
DD81231670A 1980-07-12 1981-07-10 Verfahren zur herstellung von 3,1-benzoxazin-2-onen DD202018A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803026534 DE3026534A1 (de) 1980-07-12 1980-07-12 3,1-benzoxazin-2-one, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
DD202018A5 true DD202018A5 (de) 1983-08-24

Family

ID=6107085

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81231670A DD202018A5 (de) 1980-07-12 1981-07-10 Verfahren zur herstellung von 3,1-benzoxazin-2-onen

Country Status (25)

Country Link
US (1) US4341778A (ko)
EP (1) EP0043940B1 (ko)
JP (1) JPS5748975A (ko)
KR (1) KR850000755B1 (ko)
AT (1) ATE9336T1 (ko)
AU (1) AU540916B2 (ko)
CA (1) CA1165317A (ko)
DD (1) DD202018A5 (ko)
DE (2) DE3026534A1 (ko)
DK (1) DK149851C (ko)
ES (4) ES503837A0 (ko)
FI (1) FI74703C (ko)
GB (1) GB2080296B (ko)
GR (1) GR74333B (ko)
HK (1) HK98286A (ko)
HU (1) HU183515B (ko)
IE (1) IE52508B1 (ko)
IL (1) IL63285A (ko)
NO (1) NO158578C (ko)
NZ (1) NZ197678A (ko)
PH (1) PH17425A (ko)
PT (1) PT73338B (ko)
SG (1) SG77686G (ko)
YU (1) YU170181A (ko)
ZA (1) ZA814687B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446319A (en) * 1981-04-28 1984-05-01 Takeda Chemical Industries, Ltd. Aminocyclitols and their production
JPS62238288A (ja) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk 環状カルバメ−ト及び農園芸用殺菌剤
FR2636065B1 (fr) * 1988-09-08 1993-05-07 Fabre Sa Pierre Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
FR2680172B1 (fr) * 1991-08-05 1993-11-19 Fabre Medicament Pierre Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
EP0805681A4 (en) * 1995-01-24 1998-05-06 Merck & Co Inc TOCOLYTIC ANTAGONISTS OF OXYTOCIN RECEPTORS
US5874430A (en) * 1996-10-02 1999-02-23 Dupont Pharmaceuticals Company 4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same
DE102004003428A1 (de) * 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
EP1844768A1 (en) * 2005-01-19 2007-10-17 Dainippon Sumitomo Pharma Co., Ltd. Aromatic sulfone compound as aldosterone receptor modulator
DE102005008921A1 (de) * 2005-02-24 2006-08-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
US7423146B2 (en) * 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
UY30552A1 (es) * 2006-08-22 2008-03-31 Boehringer Ingelheim Int Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones
PE20080610A1 (es) * 2006-08-22 2008-07-15 Boehringer Ingelheim Int Nuevos beta-agonistas enantiomericamente puros, procedimientos para su preparacion y uso como medicamentos
PE20080425A1 (es) * 2006-08-22 2008-06-16 Boehringer Ingelheim Int Formulacion aerosol para la inhalacion de beta-agonistas
US20100233268A1 (en) * 2006-08-22 2010-09-16 Boehringer Ingelheim International Gmbh Powder formulations for inhalation containing enantiomerically pure beta-agonists
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526621A (en) * 1966-08-03 1970-09-01 Farmaceutical Italia Soc Substituted 3,1-benzoxazin-2-one
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
US4163053A (en) * 1977-12-27 1979-07-31 Schering Corporation Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
FI791727A (fi) * 1978-06-05 1979-12-06 Ciba Geigy Ag Foerfarande foer framstaellning av n-alkylerade aminoalkoholer
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen

Also Published As

Publication number Publication date
FI812183L (fi) 1982-01-13
NO158578C (no) 1988-10-05
ES8300725A1 (es) 1982-11-01
HK98286A (en) 1986-12-24
IL63285A0 (en) 1981-10-30
US4341778A (en) 1982-07-27
IL63285A (en) 1985-03-31
GB2080296A (en) 1982-02-03
NZ197678A (en) 1984-12-14
ES508655A0 (es) 1982-11-01
KR850000755B1 (en) 1985-05-25
AU7273181A (en) 1982-09-16
ES8205402A1 (es) 1982-06-01
DE3026534A1 (de) 1982-03-18
DK149851B (da) 1986-10-13
EP0043940A1 (de) 1982-01-20
KR830006248A (ko) 1983-09-20
GB2080296B (en) 1983-09-28
HU183515B (en) 1984-05-28
IE52508B1 (en) 1987-11-25
ES503837A0 (es) 1982-06-01
GR74333B (ko) 1984-06-25
FI74703C (fi) 1988-03-10
ATE9336T1 (de) 1984-09-15
JPS5748975A (en) 1982-03-20
DK306781A (da) 1982-01-13
SG77686G (en) 1987-02-27
EP0043940B1 (de) 1984-09-12
ZA814687B (en) 1983-03-30
YU170181A (en) 1983-10-31
NO812355L (no) 1982-01-13
ES508653A0 (es) 1982-11-01
ES8300726A1 (es) 1982-11-01
ES8300727A1 (es) 1982-11-01
DK149851C (da) 1987-05-04
AU540916B2 (en) 1984-12-06
DE3166003D1 (en) 1984-10-18
PH17425A (en) 1984-08-08
IE811567L (en) 1982-01-12
PT73338B (en) 1983-06-20
ES508654A0 (es) 1982-11-01
PT73338A (de) 1981-08-01
FI74703B (fi) 1987-11-30
NO158578B (no) 1988-06-27
CA1165317A (en) 1984-04-10

Similar Documents

Publication Publication Date Title
EP0054168B1 (de) 1,1,2-Triphenyl-but-1-en-Derivate sowie Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DD202018A5 (de) Verfahren zur herstellung von 3,1-benzoxazin-2-onen
DE2220480A1 (de) Polymethylendiamine
DE2461604A1 (de) 8-hydroxy-3,4-dihydrocarbostyril- derivate, verfahren zu ihrer herstellung und arzneimittel
DE1962497A1 (de) Naphthylalkylamine
DE1593027A1 (de) Alkensaeuren und Verfahren zu ihrer Herstellung
DE2531312A1 (de) Aminderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
EP0064685A1 (de) Dibenzo(de,g)chinolin-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DD279238A5 (de) Verfahren zur herstellung von benzocycloheptenderivaten
DE1943150A1 (de) Chemische Verfahren
DE1568929A1 (de) Aminosubstituierte Indane und Tetraline sowie Verfahren zu deren Herstellung
DE3101093C2 (ko)
DE2834107A1 (de) Benzylalkoholderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE3014738C2 (ko)
EP0027928A2 (de) Piperidinderivate von 4,5-Dialkyl-3-hydroxy-pyrrol-2-carbonsäureestern, ihre Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0104445A2 (de) Piperidinochinoxalin-Derivate, ihre Herstellung und Verwendung
DE2633245A1 (de) 4-hydroxy-1,3-benzoldimethanolverbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2240211A1 (de) Fluorsubstituierte 3-(methylamino)- und 3-(dimethylamino)-tetrahydrocarbazole
DE1618643A1 (de) Aryloxysubstituierte Carbonsaeuren und Verfahren zu deren Herstellung
DE2421165A1 (de) N-substituierte dihydroxyphenylaethylamine
DE2736106A1 (de) Neuartige aryloxy-1-amino-3-propanole-2, verfahren zum herstellen und therapeutische anwendung derselben
DE1768764A1 (de) Chemische Verfahren und Produkte
DE1545786A1 (de) Verfahren zur Herstellung von Carbonsaeure-N-methylpiperaziden
DE2950064A1 (de) Piperidinderivate von 3-hydroxythiophen-2-carbonsaeure und -estern, ihre herstellung und diese enthaltende pharmazeutische zubereitungen
EP0029992A1 (de) Neue Aminopropanolderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel