DD201593A5 - Verfahren zur herstellung von im a-ring substituierten apovincaminol-3,4,5-trimethoxybenzoaten - Google Patents

Verfahren zur herstellung von im a-ring substituierten apovincaminol-3,4,5-trimethoxybenzoaten Download PDF

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Publication number
DD201593A5
DD201593A5 DD82237317A DD23731782A DD201593A5 DD 201593 A5 DD201593 A5 DD 201593A5 DD 82237317 A DD82237317 A DD 82237317A DD 23731782 A DD23731782 A DD 23731782A DD 201593 A5 DD201593 A5 DD 201593A5
Authority
DD
German Democratic Republic
Prior art keywords
acid
compounds
apovincaminol
general formula
solution
Prior art date
Application number
DD82237317A
Other languages
German (de)
English (en)
Inventor
Maria Zajer
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Egon Karpati
Gyoengyver Kiraly
Arpad Kiraly
Laszlo Szporny
Bela Rosdy
Lilla Forgach
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DD201593A5 publication Critical patent/DD201593A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD82237317A 1981-02-11 1982-02-10 Verfahren zur herstellung von im a-ring substituierten apovincaminol-3,4,5-trimethoxybenzoaten DD201593A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU81324A HU183326B (en) 1981-02-11 1981-02-11 Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted in the a ring and acid addition salts thereof

Publications (1)

Publication Number Publication Date
DD201593A5 true DD201593A5 (de) 1983-07-27

Family

ID=10949091

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82237317A DD201593A5 (de) 1981-02-11 1982-02-10 Verfahren zur herstellung von im a-ring substituierten apovincaminol-3,4,5-trimethoxybenzoaten

Country Status (22)

Country Link
US (1) US4432982A (it)
JP (1) JPS57150685A (it)
AR (1) AR228385A1 (it)
AT (1) AT382375B (it)
AU (1) AU545745B2 (it)
BE (1) BE892070A (it)
CA (1) CA1199637A (it)
DD (1) DD201593A5 (it)
DE (1) DE3204588A1 (it)
DK (1) DK151022C (it)
ES (1) ES509418A0 (it)
FI (1) FI70019C (it)
FR (1) FR2499573B1 (it)
GB (1) GB2096597B (it)
GR (1) GR75858B (it)
HU (1) HU183326B (it)
IT (1) IT1157921B (it)
NL (1) NL8200493A (it)
NO (1) NO820395L (it)
PT (1) PT74402B (it)
SE (1) SE8200524L (it)
SU (1) SU1069626A3 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU192013B (en) * 1984-04-25 1987-04-28 Richter Gedeon Vegyeszet Process for production of new aporincavinol esther derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035784A1 (en) * 1969-03-27 1970-12-24 Olivier Louisette Vincamine derivs with therapeutic propert- - ies
DK139358B (da) * 1973-12-18 1979-02-05 Sandoz Ag Analogifremgangsmåde til fremstilling af vincaminderivater eller syreadditionssalte deraf.
US4146643A (en) * 1973-12-18 1979-03-27 Sandoz Ltd. Increasing vigilance or treating cerebral insufficiency with substituted vincamines
US4123535A (en) * 1974-09-06 1978-10-31 Sandoz Ltd. Psychostimulating 14-amino-14,15-dihydroeburnamenines
HU170888B (hu) * 1975-06-10 1977-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov
HU177370B (en) * 1977-07-27 1981-09-28 Richter Gedeon Vegyeszet Process for producing new bracket-cross-bracket-vincaminol-esters
IL60613A (en) * 1979-08-16 1983-12-30 Richter Gedeon Vegyeszet Dermatological compositions applicable directly to the skin comprising an eburnamenine derivative and process for their preparation

Also Published As

Publication number Publication date
ES8307803A1 (es) 1983-08-01
SE8200524L (sv) 1982-08-12
DK151022B (da) 1987-10-12
NL8200493A (nl) 1982-09-01
DE3204588C2 (it) 1990-10-04
US4432982A (en) 1984-02-21
HU183326B (en) 1984-04-28
BE892070A (fr) 1982-08-09
FI70019C (fi) 1986-09-12
AR228385A1 (es) 1983-02-28
GR75858B (it) 1984-08-02
AU545745B2 (en) 1985-08-01
ATA26282A (de) 1986-07-15
JPS57150685A (en) 1982-09-17
GB2096597A (en) 1982-10-20
FI820364L (fi) 1982-08-12
IT1157921B (it) 1987-02-18
DK57682A (da) 1982-08-12
SU1069626A3 (ru) 1984-01-23
DK151022C (da) 1988-06-20
FR2499573A1 (fr) 1982-08-13
CA1199637A (en) 1986-01-21
AU8033982A (en) 1982-08-19
IT8219588A0 (it) 1982-02-10
PT74402B (en) 1983-07-07
JPH0378393B2 (it) 1991-12-13
FI70019B (fi) 1986-01-31
NO820395L (no) 1982-08-12
AT382375B (de) 1987-02-25
ES509418A0 (es) 1983-08-01
GB2096597B (en) 1984-10-24
DE3204588A1 (de) 1982-12-30
FR2499573B1 (fr) 1985-12-27
PT74402A (en) 1982-03-01

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