DD200469A5 - Verfahren zur herstellung von als histamin-h tief 2-rezeptor-antagonisten wirkenden pyrimidon-derivaten - Google Patents
Verfahren zur herstellung von als histamin-h tief 2-rezeptor-antagonisten wirkenden pyrimidon-derivaten Download PDFInfo
- Publication number
- DD200469A5 DD200469A5 DD81233796A DD23379681A DD200469A5 DD 200469 A5 DD200469 A5 DD 200469A5 DD 81233796 A DD81233796 A DD 81233796A DD 23379681 A DD23379681 A DD 23379681A DD 200469 A5 DD200469 A5 DD 200469A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- group
- pyridyl
- general formula
- substituted
- pyrimidone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8031685 | 1980-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD200469A5 true DD200469A5 (de) | 1983-05-04 |
Family
ID=10516418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD81233796A DD200469A5 (de) | 1980-10-01 | 1981-10-01 | Verfahren zur herstellung von als histamin-h tief 2-rezeptor-antagonisten wirkenden pyrimidon-derivaten |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4385058A (fi) |
| EP (1) | EP0049173B1 (fi) |
| JP (1) | JPS5791986A (fi) |
| KR (1) | KR830007630A (fi) |
| AT (1) | ATA420581A (fi) |
| AU (1) | AU547215B2 (fi) |
| CA (1) | CA1170261A (fi) |
| DD (1) | DD200469A5 (fi) |
| DE (1) | DE3171234D1 (fi) |
| DK (1) | DK435681A (fi) |
| ES (1) | ES505898A0 (fi) |
| FI (1) | FI813054L (fi) |
| GR (1) | GR75783B (fi) |
| IL (1) | IL63913A0 (fi) |
| NO (1) | NO813326L (fi) |
| PH (2) | PH17950A (fi) |
| PL (1) | PL233256A1 (fi) |
| PT (1) | PT73691B (fi) |
| RO (1) | RO82214A (fi) |
| YU (1) | YU236881A (fi) |
| ZA (1) | ZA816794B (fi) |
| ZW (1) | ZW21281A1 (fi) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT74865B (en) * | 1981-05-27 | 1983-12-07 | Smithkline Beckman Corp | Process of preparing a 2-(pyridylbutylamino)-pyrimidone and of its pharmaceutically acceptable salts |
| ZA823149B (en) * | 1981-05-27 | 1983-03-30 | Smithkline Beckman Corp | Chemical process |
| US4808589A (en) * | 1982-02-20 | 1989-02-28 | Smith Kline & French Laboratories Limited | Pyrimidone derivatives |
| EP0089765A3 (en) * | 1982-03-17 | 1984-05-23 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
| EP0102157B1 (en) * | 1982-07-30 | 1986-09-03 | Smith Kline & French Laboratories Limited | Amino pyrimidinones and their preparation |
| PT77287B (en) * | 1982-10-01 | 1986-02-04 | Smith Kline French Lab | Compound |
| AU1956283A (en) * | 1982-10-02 | 1984-04-05 | Smith Kline & French Laboratories Limited | 1-(3-(4-(substited aminomethyl)pyrid-2-yl-oxy)-prop-1-yl- amino) - 2-aminocyclobut-i-ene-3,4-diones |
| PT77623B (en) * | 1982-11-25 | 1986-03-19 | Smith Kline French Lab | Process for the preparation of a small class of histamine h2-antagonists |
| JO1274B1 (en) * | 1982-12-03 | 1985-04-20 | سيدني ساخ جورج | Pyridine derivatives |
| EP0112707B1 (en) * | 1982-12-23 | 1987-11-04 | Smith Kline & French Laboratories Limited | Aminopyrimidinone derivatives as histamine h1-antagonists |
| DE3375574D1 (en) * | 1982-12-23 | 1988-03-10 | Smith Kline French Lab | Pyridine derivatives |
| GB8311443D0 (en) * | 1983-04-27 | 1983-06-02 | Smith Kline French Lab | Chemical compounds |
| GB8318638D0 (en) * | 1983-07-09 | 1983-08-10 | Smith Kline French Lab | Chemical compounds |
| GB8319874D0 (en) * | 1983-07-23 | 1983-08-24 | Smith Kline French Lab | Compounds |
| GB8320505D0 (en) * | 1983-07-29 | 1983-09-01 | Smith Kline French Lab | Chemical compounds |
| US4772704A (en) * | 1983-09-21 | 1988-09-20 | Bristol-Myers Company | 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity |
| GB8332091D0 (en) * | 1983-12-01 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| GB8421427D0 (en) * | 1984-08-23 | 1984-09-26 | Smith Kline French Lab | Chemical compounds |
| CA1275097A (en) * | 1984-10-02 | 1990-10-09 | Fujio Nohara | Pyridyloxy derivatives |
| GB8601816D0 (en) * | 1986-01-25 | 1986-02-26 | Smith Kline French Lab | Pyridine derivatives |
| US4931452A (en) * | 1987-11-10 | 1990-06-05 | The Dow Chemical Company | N-cyanomethyl-2-pyridinone insecticides |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
| US4145546A (en) * | 1975-10-02 | 1979-03-20 | Smith Kline & French Laboratories Limited | 4-Pyrimidone compounds |
| US4218452A (en) * | 1975-10-02 | 1980-08-19 | Smith Kline & French Laboratories Limited | Substituted 4-pyrimidone compounds, compositions and methods of use |
| IN146736B (fi) * | 1975-10-02 | 1979-08-25 | Smith Kline French Lab | |
| US4154834A (en) * | 1975-12-29 | 1979-05-15 | Smith Kline & French Laboratories Limited | Substituted isocytosines having histamine H2 -antagonist activity |
| MW5076A1 (en) * | 1975-12-29 | 1978-02-08 | Smith Kline French Lab | Pharmacologicalle active compounds |
| IN151188B (fi) * | 1978-02-13 | 1983-03-05 | Smith Kline French Lab | |
| US4227000A (en) * | 1978-04-11 | 1980-10-07 | Smith Kline & French Laboratories Limited | Intermediates in the process for making histamine antagonists |
| IL57416A (en) * | 1978-05-30 | 1983-03-31 | Smith Kline French Lab | Nitro compounds,processes for preparing them and compositions containing them |
| ZA793443B (en) * | 1978-07-26 | 1980-12-31 | Glaxo Group Ltd | Heterocyclic derivatives |
| US4250316A (en) * | 1978-11-24 | 1981-02-10 | Bristol-Myers Company | Pyridyl guanidine anti-ulcer agents |
| US4255428A (en) * | 1979-03-24 | 1981-03-10 | Smith Kline & French Laboratories Limited | 5-(Hydroxypyridylalkyl)-4-pyrimidones |
| CA1140129A (en) * | 1979-08-21 | 1983-01-25 | Ronald J. King | 4-pyrimidone derivatives |
-
1981
- 1981-08-28 ZW ZW212/81A patent/ZW21281A1/xx unknown
- 1981-09-16 US US06/302,941 patent/US4385058A/en not_active Expired - Fee Related
- 1981-09-17 PT PT73691A patent/PT73691B/pt unknown
- 1981-09-22 IL IL63913A patent/IL63913A0/xx unknown
- 1981-09-26 RO RO81105409A patent/RO82214A/ro unknown
- 1981-09-30 PH PH26291A patent/PH17950A/en unknown
- 1981-09-30 ES ES505898A patent/ES505898A0/es active Granted
- 1981-09-30 GR GR66162A patent/GR75783B/el unknown
- 1981-09-30 PL PL23325681A patent/PL233256A1/xx unknown
- 1981-09-30 NO NO813326A patent/NO813326L/no unknown
- 1981-09-30 KR KR1019810003735A patent/KR830007630A/ko unknown
- 1981-09-30 CA CA000386988A patent/CA1170261A/en not_active Expired
- 1981-09-30 PH PH26291A patent/PH17948A/en unknown
- 1981-09-30 JP JP56156896A patent/JPS5791986A/ja active Granted
- 1981-10-01 EP EP81304540A patent/EP0049173B1/en not_active Expired
- 1981-10-01 YU YU02368/81A patent/YU236881A/xx unknown
- 1981-10-01 DK DK435681A patent/DK435681A/da not_active Application Discontinuation
- 1981-10-01 AT AT0420581A patent/ATA420581A/de not_active Application Discontinuation
- 1981-10-01 FI FI810354A patent/FI813054L/fi not_active Application Discontinuation
- 1981-10-01 DE DE8181304540T patent/DE3171234D1/de not_active Expired
- 1981-10-01 ZA ZA816794A patent/ZA816794B/xx unknown
- 1981-10-01 DD DD81233796A patent/DD200469A5/de unknown
- 1981-10-01 AU AU75951/81A patent/AU547215B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATA420581A (de) | 1985-03-15 |
| EP0049173A3 (en) | 1982-06-30 |
| YU236881A (en) | 1984-02-29 |
| KR830007630A (ko) | 1983-11-04 |
| GR75783B (fi) | 1984-08-02 |
| RO82214A (ro) | 1983-07-07 |
| EP0049173B1 (en) | 1985-07-03 |
| PT73691A (en) | 1981-10-01 |
| CA1170261A (en) | 1984-07-03 |
| EP0049173A2 (en) | 1982-04-07 |
| PL233256A1 (fi) | 1982-11-08 |
| ZA816794B (en) | 1982-10-27 |
| AU7595181A (en) | 1982-04-08 |
| RO82214B (ro) | 1983-06-30 |
| PT73691B (en) | 1982-12-10 |
| JPS5791986A (en) | 1982-06-08 |
| JPS6328069B2 (fi) | 1988-06-07 |
| PH17950A (en) | 1985-02-11 |
| US4385058A (en) | 1983-05-24 |
| DE3171234D1 (en) | 1985-08-08 |
| PH17948A (en) | 1985-02-11 |
| ES8301966A1 (es) | 1983-01-01 |
| IL63913A0 (en) | 1981-12-31 |
| NO813326L (no) | 1982-04-02 |
| ES505898A0 (es) | 1983-01-01 |
| ZW21281A1 (en) | 1981-11-18 |
| DK435681A (da) | 1982-04-02 |
| AU547215B2 (en) | 1985-10-10 |
| FI813054L (fi) | 1982-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A5 | Published as prov. exclusive patent |