DD159601A5 - Verfahren zur herstellung einer magnetisch lokalisierbaren bioabbaubaren arzneimitteltraegerformulierung - Google Patents
Verfahren zur herstellung einer magnetisch lokalisierbaren bioabbaubaren arzneimitteltraegerformulierung Download PDFInfo
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- DD159601A5 DD159601A5 DD81230763A DD23076381A DD159601A5 DD 159601 A5 DD159601 A5 DD 159601A5 DD 81230763 A DD81230763 A DD 81230763A DD 23076381 A DD23076381 A DD 23076381A DD 159601 A5 DD159601 A5 DD 159601A5
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- DD
- German Democratic Republic
- Prior art keywords
- item
- magnetically
- localizable
- lipid
- lipids
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- WHLATLJVYMNVTJ-UHFFFAOYSA-N methyl n-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5h-benzo[a]heptalen-7-yl)carbamate Chemical compound C1=C(OC)C(=O)C=C2C(NC(=O)OC)CCC3=CC(OC)=C(OC)C(OC)=C3C2=C1 WHLATLJVYMNVTJ-UHFFFAOYSA-N 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
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- 229940043348 myristyl alcohol Drugs 0.000 description 1
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- 239000007764 o/w emulsion Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
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- 230000008782 phagocytosis Effects 0.000 description 1
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- 239000000843 powder Substances 0.000 description 1
- 229960005205 prednisolone Drugs 0.000 description 1
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- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
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- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229940045870 sodium palmitate Drugs 0.000 description 1
- GGXKEBACDBNFAF-UHFFFAOYSA-M sodium;hexadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCC([O-])=O GGXKEBACDBNFAF-UHFFFAOYSA-M 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 235000016831 stigmasterol Nutrition 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2446/00—Magnetic particle immunoreagent carriers
- G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hard Magnetic Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/159,321 US4331654A (en) | 1980-06-13 | 1980-06-13 | Magnetically-localizable, biodegradable lipid microspheres |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD159601A5 true DD159601A5 (de) | 1983-03-23 |
Family
ID=22572067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD81230763A DD159601A5 (de) | 1980-06-13 | 1981-06-12 | Verfahren zur herstellung einer magnetisch lokalisierbaren bioabbaubaren arzneimitteltraegerformulierung |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4331654A (es) |
| EP (1) | EP0042249B1 (es) |
| JP (1) | JPS5726410A (es) |
| KR (1) | KR840002117B1 (es) |
| AR (1) | AR230189A1 (es) |
| AT (1) | ATE22799T1 (es) |
| AU (1) | AU550130B2 (es) |
| CA (1) | CA1149744A (es) |
| DD (1) | DD159601A5 (es) |
| DE (1) | DE3175461D1 (es) |
| DK (1) | DK254581A (es) |
| ES (1) | ES8203607A1 (es) |
| FI (1) | FI811828L (es) |
| GB (1) | GB2078660B (es) |
| GR (1) | GR75235B (es) |
| HU (1) | HU188099B (es) |
| IE (1) | IE51272B1 (es) |
| IL (1) | IL63077A0 (es) |
| MX (1) | MX6963E (es) |
| NZ (1) | NZ197358A (es) |
| PT (1) | PT73166B (es) |
| RO (1) | RO82719B (es) |
| YU (1) | YU144181A (es) |
| ZA (1) | ZA813865B (es) |
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| CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
| US4115534A (en) * | 1976-08-19 | 1978-09-19 | Minnesota Mining And Manufacturing Company | In vitro diagnostic test |
| DE2656317C2 (de) | 1976-12-11 | 1986-06-19 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verfahren zur Herstellung einer Suspension von beladenen Erythrocyten |
| SE431214B (sv) * | 1977-06-02 | 1984-01-23 | Klaus H Mosbach | Sett att framstella magnetiska polymerpartiklar som berare av en foretredesvis biologiskt aktiv substans |
| US4357259A (en) * | 1977-08-01 | 1982-11-02 | Northwestern University | Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres |
| US4247406A (en) * | 1979-04-23 | 1981-01-27 | Widder Kenneth J | Intravascularly-administrable, magnetically-localizable biodegradable carrier |
-
1980
- 1980-06-13 US US06/159,321 patent/US4331654A/en not_active Expired - Lifetime
-
1981
- 1981-06-09 ZA ZA00813865A patent/ZA813865B/xx unknown
- 1981-06-09 NZ NZ197358A patent/NZ197358A/en unknown
- 1981-06-09 RO RO104538A patent/RO82719B/ro unknown
- 1981-06-09 AU AU71432/81A patent/AU550130B2/en not_active Expired - Fee Related
- 1981-06-09 PT PT73166A patent/PT73166B/pt unknown
- 1981-06-09 AR AR285631A patent/AR230189A1/es active
- 1981-06-09 YU YU01441/81A patent/YU144181A/xx unknown
- 1981-06-09 CA CA000379334A patent/CA1149744A/en not_active Expired
- 1981-06-10 DE DE8181302570T patent/DE3175461D1/de not_active Expired
- 1981-06-10 AT AT81302570T patent/ATE22799T1/de active
- 1981-06-10 GB GB8117840A patent/GB2078660B/en not_active Expired
- 1981-06-10 EP EP81302570A patent/EP0042249B1/en not_active Expired
- 1981-06-11 IE IE1298/81A patent/IE51272B1/en not_active IP Right Cessation
- 1981-06-11 IL IL63077A patent/IL63077A0/xx not_active IP Right Cessation
- 1981-06-11 GR GR65218A patent/GR75235B/el unknown
- 1981-06-11 DK DK254581A patent/DK254581A/da not_active Application Discontinuation
- 1981-06-11 FI FI811828A patent/FI811828L/fi not_active Application Discontinuation
- 1981-06-12 ES ES503011A patent/ES8203607A1/es not_active Expired
- 1981-06-12 MX MX819489U patent/MX6963E/es unknown
- 1981-06-12 JP JP9146281A patent/JPS5726410A/ja active Pending
- 1981-06-12 HU HU811756A patent/HU188099B/hu unknown
- 1981-06-12 DD DD81230763A patent/DD159601A5/de unknown
- 1981-06-12 KR KR1019810002114A patent/KR840002117B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| GB2078660B (en) | 1984-01-18 |
| AU550130B2 (en) | 1986-03-06 |
| PT73166B (en) | 1982-07-16 |
| ZA813865B (en) | 1983-01-26 |
| IE51272B1 (en) | 1986-11-26 |
| RO82719A (ro) | 1984-05-23 |
| JPS5726410A (en) | 1982-02-12 |
| ES503011A0 (es) | 1982-04-16 |
| EP0042249A2 (en) | 1981-12-23 |
| YU144181A (en) | 1984-10-31 |
| GR75235B (es) | 1984-07-13 |
| DK254581A (da) | 1981-12-14 |
| FI811828L (fi) | 1981-12-14 |
| AU7143281A (en) | 1981-12-17 |
| US4331654A (en) | 1982-05-25 |
| AR230189A1 (es) | 1984-03-01 |
| KR840002117B1 (ko) | 1984-11-19 |
| IE811298L (en) | 1981-12-13 |
| PT73166A (en) | 1981-07-01 |
| NZ197358A (en) | 1984-04-27 |
| EP0042249A3 (en) | 1982-09-22 |
| DE3175461D1 (en) | 1986-11-20 |
| IL63077A0 (en) | 1981-09-13 |
| EP0042249B1 (en) | 1986-10-15 |
| HU188099B (en) | 1986-03-28 |
| ES8203607A1 (es) | 1982-04-16 |
| CA1149744A (en) | 1983-07-12 |
| GB2078660A (en) | 1982-01-13 |
| MX6963E (es) | 1987-01-08 |
| ATE22799T1 (de) | 1986-11-15 |
| KR830005873A (ko) | 1983-09-14 |
| RO82719B (ro) | 1984-07-30 |
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