DD157462A5 - Kristalline salze - Google Patents

Kristalline salze Download PDF

Info

Publication number
DD157462A5
DD157462A5 DD81227278A DD22727881A DD157462A5 DD 157462 A5 DD157462 A5 DD 157462A5 DD 81227278 A DD81227278 A DD 81227278A DD 22727881 A DD22727881 A DD 22727881A DD 157462 A5 DD157462 A5 DD 157462A5
Authority
DD
German Democratic Republic
Prior art keywords
amino
carboxylic acid
thiazolyl
cephem
hydrochloride
Prior art date
Application number
DD81227278A
Other languages
German (de)
English (en)
Inventor
Riccardo Scartazzini
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DD157462A5 publication Critical patent/DD157462A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Magnetic Heads (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Liquid Crystal Substances (AREA)
  • Seasonings (AREA)
DD81227278A 1980-02-01 1981-01-28 Kristalline salze DD157462A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH83680 1980-02-01

Publications (1)

Publication Number Publication Date
DD157462A5 true DD157462A5 (de) 1982-11-10

Family

ID=4196332

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81227278A DD157462A5 (de) 1980-02-01 1981-01-28 Kristalline salze

Country Status (26)

Country Link
US (1) US4411897A (ja)
EP (1) EP0033518B1 (ja)
JP (1) JPS56122382A (ja)
KR (1) KR840000502B1 (ja)
AT (1) ATE3550T1 (ja)
AU (1) AU6677981A (ja)
CA (1) CA1146540A (ja)
CS (1) CS219851B2 (ja)
DD (1) DD157462A5 (ja)
DE (1) DE3160328D1 (ja)
DK (1) DK32081A (ja)
ES (1) ES8204439A1 (ja)
FI (1) FI66874B (ja)
GR (1) GR78221B (ja)
IE (1) IE50888B1 (ja)
IL (1) IL62017A (ja)
MC (1) MC1367A1 (ja)
MT (1) MTP882B (ja)
NO (1) NO810338L (ja)
NZ (1) NZ196159A (ja)
OA (1) OA06732A (ja)
PL (1) PL125899B1 (ja)
PT (1) PT72421A (ja)
SU (1) SU1036250A1 (ja)
ZA (1) ZA81631B (ja)
ZW (1) ZW2281A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2111043B (en) * 1980-12-12 1985-02-06 Ciba Geigy Ag Novel cephalosporin esters
US4400503A (en) * 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
JPS60190783A (ja) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk セフエム系化合物
US4683227A (en) * 1985-07-09 1987-07-28 Eli Lilly And Company Antibiotic derivatives of 7β-[2-(thiazol-4-yl)acetamide]-3-chloro-3-cephem-4-carboxylic acids and compositions and method of use thereof
JPH02101081A (ja) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
US20040067192A1 (en) * 2002-10-07 2004-04-08 The Procter & Gamble Company Conversion of sodium bromide to anhydrous hydrobromic acid and sodium bisulfate
EP1606293B1 (en) * 2003-03-27 2009-08-19 Basilea Pharmaceutica AG Cephalosporin in crystalline form

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
GB2025933B (en) 1978-06-13 1982-10-27 Fujisawa Pharmaceutical Co Cephem and cepham compounds
MA18686A1 (fr) * 1978-07-07 1980-10-01 Ciba Geigy Ag Composes aminothiazoliques
JPS5543011A (en) * 1978-09-20 1980-03-26 Shionogi & Co Ltd 7-halothiazolylalkoxyiminoacetamido-3-cephem compound
JPS5579393A (en) * 1978-12-11 1980-06-14 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal

Also Published As

Publication number Publication date
PL229457A1 (ja) 1981-10-02
PT72421A (de) 1981-02-01
ES498989A0 (es) 1982-05-01
AU6677981A (en) 1981-08-06
CA1146540A (en) 1983-05-17
PL125899B1 (en) 1983-06-30
MTP882B (en) 1984-06-05
DE3160328D1 (en) 1983-07-07
KR840000502B1 (ko) 1984-04-16
CS219851B2 (en) 1983-03-25
NZ196159A (en) 1983-09-30
ES8204439A1 (es) 1982-05-01
ZW2281A1 (en) 1981-09-02
FI810270L (fi) 1981-08-02
US4411897A (en) 1983-10-25
EP0033518B1 (de) 1983-05-25
ATE3550T1 (de) 1983-06-15
FI66874B (fi) 1984-08-31
IE810176L (en) 1981-08-01
EP0033518A1 (de) 1981-08-12
DK32081A (da) 1981-08-02
JPS56122382A (en) 1981-09-25
ZA81631B (en) 1982-02-24
IE50888B1 (en) 1986-08-06
IL62017A (en) 1984-06-29
OA06732A (fr) 1982-06-30
NO810338L (no) 1981-08-03
IL62017A0 (en) 1981-02-27
MC1367A1 (fr) 1981-10-23
KR830005235A (ko) 1983-08-03
GR78221B (ja) 1984-09-26
SU1036250A1 (ru) 1983-08-15

Similar Documents

Publication Publication Date Title
DE69318077T2 (de) Triazolylthiomethylthiocephalosporin-Hydrochlorid, sein kristallines Hydrat und seine Herstellung
DE19546249A1 (de) Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2332878C2 (de) Salze von Cephalosporinen mit Arginin und Lysin, ihre Herstellung und injizierbare pharmazeutische Zubereitungen
DE202004021381U1 (de) Salz einer Sulfonsäure mit Clopidogrel und dessen Verwendung zur Herstellung pharmazeutischer Formulierungen
DE2812625A1 (de) Oximderivate der 3-acetoxymethyl-7- aminothiazolyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische mittel
DD284807A5 (de) Verf. z. herstellung eine pyhsikalischen gemisches aus mindestens einem salz des ((1-methyl-1-pyrrolidinio)- methyl)-3-cephem-4-carboxylats u. einer pharmazeutisch vertraeglichen, nicht toxischen, organischen oder anorganischen base
DE2702501A1 (de) Neue oxime der 7-aminothiazolylacetamidocephalosporansaeure, herstellungsverfahren und pharmazeutische zusammensetzungen
DD210279A5 (de) Verfahren zur herstellung von cephalosporinverbindungen
DD157462A5 (de) Kristalline salze
DD267490A5 (de) Verfahren zur herstellung von wasserfreiem, kristallinem natriumsalz von 5-chlor-3-(2-thenoyl)-2-odindol-1-carboxamid
EP0137441A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DD215552A5 (de) Verfahren zur herstellung von kristallisierten cephem-saeureadditionssalzen
DE3500090C2 (ja)
EP0280157B1 (de) Kristallisierte Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
DE68922127T2 (de) Zinkceftiofurkomplexe.
DE3885031T2 (de) Wasserlösliches antibiotisches Präparat und wasserlösliche Salze von Cephem-Verbindungen.
AT390616B (de) Verfahren zur herstellung von neuem, kristallinem cephalexinhydrochloridmonohydrat und dessen verwendung zur herstellung eines arzneimittels
DE69131753T2 (de) Antibakterielle penem-esterderivate
US4189479A (en) Cephalosporin esters
EP0107138B1 (de) Neue Cephalosporine und Verfahren zu ihrer Herstellung
DE2614669A1 (de) Gamma-kristalline wasserfreie form von 7-(d-alpha-formyloxy-alpha-phenylacetamido)-3-(1-methyl-1h-tetrazol-5- ylthiomehtyl)-3-cephem-4-natriumcarboxylat und verfahren zu ihrer herstellung
DE69030502T2 (de) Cephalosporinverbindungen und deren herstellung
DE3789264T2 (de) Beta-lactam-antibiotika.
DE2234280B2 (de) Cephalosporinverbindungen und Verfahren zu deren Herstellung
US4737492A (en) Sparingly soluble salts of cefamandole, and ophthalmic compositions containing same