DD130352A5 - Verfahren zur herstellung von prostaglandin-derivaten - Google Patents

Verfahren zur herstellung von prostaglandin-derivaten

Info

Publication number
DD130352A5
DD130352A5 DD7700198124A DD19812477A DD130352A5 DD 130352 A5 DD130352 A5 DD 130352A5 DD 7700198124 A DD7700198124 A DD 7700198124A DD 19812477 A DD19812477 A DD 19812477A DD 130352 A5 DD130352 A5 DD 130352A5
Authority
DD
German Democratic Republic
Prior art keywords
production
prostaglandine derivatives
prostaglandine
derivatives
Prior art date
Application number
DD7700198124A
Other languages
German (de)
English (en)
Inventor
Souli Nanthavong
Charles Pigerol
Pierre Eymard
Jacques Simiand
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Publication of DD130352A5 publication Critical patent/DD130352A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126Acids containing more than four carbon atoms
    • C07C53/128Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
DD7700198124A 1976-03-31 1977-03-29 Verfahren zur herstellung von prostaglandin-derivaten DD130352A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49325A IL49325A (en) 1976-03-31 1976-03-31 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DD130352A5 true DD130352A5 (de) 1978-03-22

Family

ID=11048789

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700198124A DD130352A5 (de) 1976-03-31 1977-03-29 Verfahren zur herstellung von prostaglandin-derivaten

Country Status (18)

Country Link
US (1) US4115401A (fr)
JP (1) JPS52142060A (fr)
BE (1) BE852941A (fr)
CA (1) CA1074804A (fr)
CH (2) CH624101A5 (fr)
DD (1) DD130352A5 (fr)
DE (1) DE2714129A1 (fr)
ES (1) ES457385A1 (fr)
FR (1) FR2346332A1 (fr)
GB (1) GB1574246A (fr)
HU (1) HU178040B (fr)
IL (1) IL49325A (fr)
IT (1) IT1075373B (fr)
NL (1) NL7703503A (fr)
NO (1) NO149428C (fr)
PL (3) PL107544B1 (fr)
SE (1) SE417603B (fr)
SU (3) SU676162A3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7905375A (nl) * 1978-07-11 1980-01-15 Glaxo Group Ltd Prostanoiden, werkwijze voor het bereiden daarvan, en daarop gebaseerde farmaceutische preparaten.
US4320136A (en) * 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4456613A (en) * 1982-12-27 1984-06-26 E. I. Du Pont De Nemours And Company 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof
US4530933A (en) * 1982-12-27 1985-07-23 E. I. Du Pont De Nemours And Company 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents
CN1413190A (zh) 1999-12-22 2003-04-23 辉瑞产品公司 治疗骨质疏松的ep4受体选择性激动剂
IL155368A0 (en) * 2000-11-27 2003-11-23 Pfizer Prod Inc Ep4 receptor selective agonists in the treatment of osteoporosis
EP1408961B1 (fr) * 2001-07-16 2007-07-11 F. Hoffmann-La Roche Ag Derives de pyrrolidone comme antagonistes de prostanoide
ES2254726T3 (es) 2001-07-16 2006-06-16 F. Hoffmann-La Roche Ag Analogos de prostaglandina como agonistas receptores de ep4.
HU230421B1 (hu) 2001-07-23 2016-05-30 Ono Pharmaceutical Co., Ltd Csonttömegveszteséggel kapcsolatos betegségek kezelésére adható, EP4 agonistát tartalmazó gyógyászati készítmények és hatóanyagként alkalmazható vegyületek
EP1481976B1 (fr) 2002-03-05 2012-11-07 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif
AU2003209571A1 (en) * 2002-03-18 2003-09-29 Pfizer Products Inc. Use of selective ep4 receptor agonists for the treatment of liver failure, loss of patency of the ductus arteriosus, glaucoma or ocular hypertension
WO2004063158A1 (fr) * 2003-01-10 2004-07-29 F.Hoffmann-La Roche Ag Derives de 2-piperidone agonistes de la prostaglandine
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US20080058375A1 (en) * 2004-01-08 2008-03-06 Elworthy Todd R 2-Piperidone derivatives as prostaglandin antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones

Also Published As

Publication number Publication date
GB1574246A (en) 1980-09-03
FR2346332B1 (fr) 1980-05-09
PL108289B1 (pl) 1980-03-31
SE7703698L (sv) 1977-10-01
PL197005A1 (pl) 1978-10-09
SE417603B (sv) 1981-03-30
CH628032A5 (fr) 1982-02-15
BE852941A (fr) 1977-09-28
NL7703503A (nl) 1977-10-04
ES457385A1 (es) 1978-02-01
FR2346332A1 (fr) 1977-10-28
NO149428C (no) 1984-04-18
PL107643B1 (pl) 1980-02-29
JPS52142060A (en) 1977-11-26
DE2714129A1 (de) 1977-10-13
PL107544B1 (pl) 1980-02-29
CA1074804A (fr) 1980-04-01
NO149428B (no) 1984-01-09
SU837321A3 (ru) 1981-06-07
IT1075373B (it) 1985-04-22
SU715019A3 (ru) 1980-02-05
US4115401A (en) 1978-09-19
SU676162A3 (ru) 1979-07-25
IL49325A0 (en) 1976-05-31
NO771134L (no) 1977-10-03
CH624101A5 (fr) 1981-07-15
IL49325A (en) 1979-11-30
HU178040B (en) 1982-02-28

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