FR2346332B1 - - Google Patents

Info

Publication number
FR2346332B1
FR2346332B1 FR7709650A FR7709650A FR2346332B1 FR 2346332 B1 FR2346332 B1 FR 2346332B1 FR 7709650 A FR7709650 A FR 7709650A FR 7709650 A FR7709650 A FR 7709650A FR 2346332 B1 FR2346332 B1 FR 2346332B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7709650A
Other versions
FR2346332A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Publication of FR2346332A1 publication Critical patent/FR2346332A1/fr
Application granted granted Critical
Publication of FR2346332B1 publication Critical patent/FR2346332B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
FR7709650A 1976-03-31 1977-03-31 Nouveaux derives de prostaglandine, leur procede de preparation ainsi que les compositions therapeutiques les contenant Granted FR2346332A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49325A IL49325A (en) 1976-03-31 1976-03-31 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
FR2346332A1 FR2346332A1 (fr) 1977-10-28
FR2346332B1 true FR2346332B1 (fr) 1980-05-09

Family

ID=11048789

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7709650A Granted FR2346332A1 (fr) 1976-03-31 1977-03-31 Nouveaux derives de prostaglandine, leur procede de preparation ainsi que les compositions therapeutiques les contenant

Country Status (18)

Country Link
US (1) US4115401A (fr)
JP (1) JPS52142060A (fr)
BE (1) BE852941A (fr)
CA (1) CA1074804A (fr)
CH (2) CH624101A5 (fr)
DD (1) DD130352A5 (fr)
DE (1) DE2714129A1 (fr)
ES (1) ES457385A1 (fr)
FR (1) FR2346332A1 (fr)
GB (1) GB1574246A (fr)
HU (1) HU178040B (fr)
IL (1) IL49325A (fr)
IT (1) IT1075373B (fr)
NL (1) NL7703503A (fr)
NO (1) NO149428C (fr)
PL (3) PL108289B1 (fr)
SE (1) SE417603B (fr)
SU (3) SU676162A3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1117403B (it) * 1978-07-11 1986-02-17 Glaxo Group Ltd Composti prostanoidi e procedimento per produrli
US4320136A (en) * 1980-08-11 1982-03-16 E. I. Du Pont De Nemours And Company 8-Aza-16,16-difluoroprostanoids
US4530933A (en) * 1982-12-27 1985-07-23 E. I. Du Pont De Nemours And Company 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents
US4456613A (en) * 1982-12-27 1984-06-26 E. I. Du Pont De Nemours And Company 6-Keto- and 6-hydroxy-8-azaprostanoids and anti-ulcer use thereof
CN1413190A (zh) 1999-12-22 2003-04-23 辉瑞产品公司 治疗骨质疏松的ep4受体选择性激动剂
HUP0400807A2 (hu) 2000-11-27 2004-07-28 Pfizer Products Inc. EP4 receptor szelektív agonisták csontritkulás kezelésében
RU2296122C2 (ru) * 2001-07-16 2007-03-27 Ф.Хоффманн-Ля Рош Аг Производные 2-пирролидона в качестве простаноидных агонистов и фармацевтическая композиция
PL368046A1 (en) 2001-07-16 2005-03-21 F.Hoffmann-La Roche Ag Prostaglandin analogues_as ep4 receptor agonists
CA2454584C (fr) * 2001-07-23 2009-09-22 Ono Pharmaceutical Co., Ltd. Composition pharmaceutique contenant un agoniste de ep4 en tant que proncipe actif destinee au traitement des maladies associees a une perte de la masse osseuse
NZ535024A (en) 2002-03-05 2006-10-27 Ono Pharmaceutical Co 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient
MXPA04009036A (es) * 2002-03-18 2005-01-25 Pfizer Prod Inc Uso de agonistas del receptor ep4 selectivos para el tratamiento de la insuficiencia hepatica, perdida de permeabilidad del ductus arterioso, glaucoma o hipertension ocular.
RU2311409C2 (ru) * 2003-01-10 2007-11-27 Ф.Хоффманн-Ля Рош Аг Производные 2-пиперидона в качестве агонистов простагландина
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US20080058375A1 (en) * 2004-01-08 2008-03-06 Elworthy Todd R 2-Piperidone derivatives as prostaglandin antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones

Also Published As

Publication number Publication date
BE852941A (fr) 1977-09-28
SE417603B (sv) 1981-03-30
IT1075373B (it) 1985-04-22
SU715019A3 (ru) 1980-02-05
GB1574246A (en) 1980-09-03
DD130352A5 (de) 1978-03-22
NO771134L (no) 1977-10-03
CH624101A5 (fr) 1981-07-15
HU178040B (en) 1982-02-28
FR2346332A1 (fr) 1977-10-28
PL107643B1 (pl) 1980-02-29
SE7703698L (sv) 1977-10-01
SU676162A3 (ru) 1979-07-25
DE2714129A1 (de) 1977-10-13
NO149428B (no) 1984-01-09
PL107544B1 (pl) 1980-02-29
CH628032A5 (fr) 1982-02-15
SU837321A3 (ru) 1981-06-07
JPS52142060A (en) 1977-11-26
NO149428C (no) 1984-04-18
IL49325A0 (en) 1976-05-31
ES457385A1 (es) 1978-02-01
NL7703503A (nl) 1977-10-04
US4115401A (en) 1978-09-19
IL49325A (en) 1979-11-30
PL108289B1 (pl) 1980-03-31
PL197005A1 (pl) 1978-10-09
CA1074804A (fr) 1980-04-01

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Legal Events

Date Code Title Description
TP Transmission of property
CA Change of address
CD Change of name or company name
ST Notification of lapse