CZ45594A3 - Cosmetic preparation for the control of skin wrinkles and/or atrophy and the utilization thereof - Google Patents
Cosmetic preparation for the control of skin wrinkles and/or atrophy and the utilization thereof Download PDFInfo
- Publication number
- CZ45594A3 CZ45594A3 CS94455A CS4559492A CZ45594A3 CZ 45594 A3 CZ45594 A3 CZ 45594A3 CS 94455 A CS94455 A CS 94455A CS 4559492 A CS4559492 A CS 4559492A CZ 45594 A3 CZ45594 A3 CZ 45594A3
- Authority
- CZ
- Czechia
- Prior art keywords
- zinc
- skin
- composition
- alkyl
- present
- Prior art date
Links
- 230000037303 wrinkles Effects 0.000 title claims abstract description 24
- 239000002537 cosmetic Substances 0.000 title claims description 32
- 206010003694 Atrophy Diseases 0.000 title claims description 7
- 230000037444 atrophy Effects 0.000 title claims description 7
- 239000000203 mixture Substances 0.000 claims abstract description 126
- 229940121363 anti-inflammatory agent Drugs 0.000 claims abstract description 22
- 239000002260 anti-inflammatory agent Substances 0.000 claims abstract description 22
- 230000001105 regulatory effect Effects 0.000 claims abstract description 19
- 239000013543 active substance Substances 0.000 claims abstract description 17
- 150000003839 salts Chemical class 0.000 claims abstract description 14
- 239000002738 chelating agent Substances 0.000 claims abstract description 13
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 12
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 10
- 150000004492 retinoid derivatives Chemical class 0.000 claims abstract description 9
- 150000001875 compounds Chemical class 0.000 claims abstract description 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 3
- VILAVOFMIJHSJA-UHFFFAOYSA-N dicarbon monoxide Chemical compound [C]=C=O VILAVOFMIJHSJA-UHFFFAOYSA-N 0.000 claims abstract description 3
- 239000011593 sulfur Substances 0.000 claims abstract description 3
- 229910052717 sulfur Inorganic materials 0.000 claims abstract description 3
- 238000000034 method Methods 0.000 claims description 28
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 27
- 230000037373 wrinkle formation Effects 0.000 claims description 27
- 125000000217 alkyl group Chemical group 0.000 claims description 16
- 239000011787 zinc oxide Substances 0.000 claims description 14
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims description 13
- 230000000475 sunscreen effect Effects 0.000 claims description 13
- 239000000516 sunscreening agent Substances 0.000 claims description 13
- 150000003751 zinc Chemical class 0.000 claims description 11
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims description 10
- 150000001907 coumarones Chemical class 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 9
- 239000011592 zinc chloride Substances 0.000 claims description 5
- 235000005074 zinc chloride Nutrition 0.000 claims description 5
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 claims description 4
- 239000004246 zinc acetate Substances 0.000 claims description 4
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 claims description 4
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 4
- 229910000368 zinc sulfate Inorganic materials 0.000 claims description 4
- 229960001763 zinc sulfate Drugs 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 abstract description 11
- 125000004122 cyclic group Chemical group 0.000 abstract description 2
- 125000006702 (C1-C18) alkyl group Chemical group 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 description 54
- 210000003491 skin Anatomy 0.000 description 48
- 239000011701 zinc Substances 0.000 description 40
- -1 zinc p-phenolsulfonate octahydrate Chemical class 0.000 description 30
- 230000000699 topical effect Effects 0.000 description 29
- 206010040799 Skin atrophy Diseases 0.000 description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- 239000000243 solution Substances 0.000 description 12
- 239000003795 chemical substances by application Substances 0.000 description 10
- 239000003974 emollient agent Substances 0.000 description 10
- 239000000839 emulsion Substances 0.000 description 10
- 239000003921 oil Substances 0.000 description 10
- 235000019198 oils Nutrition 0.000 description 10
- 239000002516 radical scavenger Substances 0.000 description 10
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 9
- 229910052725 zinc Inorganic materials 0.000 description 9
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 8
- HBXWUCXDUUJDRB-UHFFFAOYSA-N 1-octadecoxyoctadecane Chemical compound CCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCC HBXWUCXDUUJDRB-UHFFFAOYSA-N 0.000 description 8
- BDOYKFSQFYNPKF-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;sodium Chemical compound [Na].[Na].OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O BDOYKFSQFYNPKF-UHFFFAOYSA-N 0.000 description 8
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 8
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- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 8
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 8
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- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 description 4
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75271491A | 1991-08-30 | 1991-08-30 | |
| PCT/US1992/007287 WO1993004669A1 (en) | 1991-08-30 | 1992-08-27 | Use of n-acetyl-l-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ45594A3 true CZ45594A3 (en) | 1994-07-13 |
Family
ID=25027496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS94455A CZ45594A3 (en) | 1991-08-30 | 1992-08-27 | Cosmetic preparation for the control of skin wrinkles and/or atrophy and the utilization thereof |
Country Status (22)
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150405A (en) * | 1985-07-18 | 2000-11-21 | Proctor; Peter H. | Hair loss treatment with ascorbates |
| US5723502A (en) * | 1985-07-18 | 1998-03-03 | Proctor; Peter H. | Topical spin trap composition and method |
| US5451405A (en) * | 1994-04-25 | 1995-09-19 | Chesebrough-Pond's Usa Co. | Skin treatment composition |
| CA2193087C (en) * | 1994-06-23 | 2002-01-08 | Greg George Hillebrand | Topical compositions comprising n-acetyl-l-cysteine |
| US5472698A (en) * | 1994-12-20 | 1995-12-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Composition for enhancing lipid production in skin |
| US5691380A (en) * | 1995-06-29 | 1997-11-25 | The Procter & Gamble Company | Stable n-acetylcysteine compositions and methods for treating human skin therewith |
| DE19533330A1 (de) * | 1995-09-11 | 1997-03-13 | Beiersdorf Ag | Gegen Hautkrebs wirksame topische Zubereitungen |
| FR2750332B1 (fr) * | 1996-06-28 | 1998-09-11 | Sincholle Daniel Paul | Composition pour la prevention et le traitement topique de la cellulite |
| FR2751217B1 (fr) * | 1996-07-16 | 2004-04-16 | Oreal | Utilisation de l'iodo-3 propynyl-2 butylcarbamate dans une composition cosmetique et/ou dermatologique comme actif pour le traitement de la seborrhee |
| US6169114B1 (en) * | 1997-09-26 | 2001-01-02 | Shiseido Company, Ltd. | Endermic liniment containing a thiol compound and zinc oxide |
| KR20010075000A (ko) | 1998-10-09 | 2001-08-09 | 에가시라 구니오 | 시스테인 유도체 |
| WO2000044341A1 (fr) * | 1999-01-28 | 2000-08-03 | Shiseido Company, Ltd. | Compositions destinees a un usage externe |
| DE10048260A1 (de) * | 2000-09-29 | 2002-04-11 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung |
| US6774154B2 (en) | 2002-04-08 | 2004-08-10 | Crompton Corporation | Semiflexible and flexible polyurethanes foams having low fogging characteristics and improved physical properties |
| ES2357571T3 (es) | 2006-07-25 | 2011-04-27 | Zambon S.P.A. | Preparaciones cosméticas o dermatológicas que comprenden la n-acetilcisteína. |
| CN100526294C (zh) * | 2006-08-21 | 2009-08-12 | 厦门大学 | 苯甲醛缩氨基半胱氨酸与制备方法及其在化妆品中的应用 |
| DE102007026718A1 (de) * | 2007-06-06 | 2008-12-11 | Henkel Ag & Co. Kgaa | Tensidhaltige Emulsion |
| JP5665276B2 (ja) | 2008-02-27 | 2015-02-04 | 花王株式会社 | 皮膚老化予防又は改善剤 |
| ES2650252T3 (es) | 2008-11-19 | 2018-01-17 | Pola Chemical Industries Inc. | Agentes antiarrugas |
| ES2638046T3 (es) | 2009-03-30 | 2017-10-18 | Shiseido Company, Ltd. | Composiciones para aliviar los daños inducidos por la radiación ultravioleta |
| GB2470040A (en) * | 2009-05-06 | 2010-11-10 | Systagenix Wound Man Ip Co Bv | Wound dressing material comprising N-acetyl cysteine |
| FR2984733B1 (fr) * | 2011-12-22 | 2016-09-30 | Oreal | Association d'un agent nucleophile et d'un agent azote ou phosphore de pka superieur a 11 pour la peau glyquee |
| US9445981B2 (en) | 2012-12-20 | 2016-09-20 | Avon Products, Inc | PLOD-2 stimulators and their use in the treatment of skin |
| US10682324B2 (en) | 2015-01-27 | 2020-06-16 | Florengale, Llc | Healing topical composition |
| AU2017364787C1 (en) * | 2016-11-28 | 2020-04-16 | Pola Chemical Industries, Inc. | Wrinkle ameliorating agent |
| WO2025021553A1 (en) * | 2023-07-25 | 2025-01-30 | Unilever Ip Holdings B.V. | A personal care composition |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA702518B (en) * | 1969-04-18 | 1971-01-27 | Bristol Myers Co | Acetylcysteine for acne |
| US3749770A (en) * | 1969-08-11 | 1973-07-31 | Mead Johnson & Co | Compositions containing zinc mercaptide n-acetylcysteine carboxylate salts |
| US3755560A (en) | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
| US4276284A (en) * | 1971-07-26 | 1981-06-30 | Brown Stuart I | Prevention of collagenase induced disease by treatment with collagenase inhibitors |
| US4017641A (en) | 1975-01-31 | 1977-04-12 | The Procter & Gamble Company | Skin moisturizing compositions containing 2-pyrrolidinone |
| US3989816A (en) | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
| GB1541463A (en) | 1975-10-11 | 1979-02-28 | Lion Dentifrice Co Ltd | Process for prparing a multiple emulsion having a dispersing form of water-phase/oil-phase/water-phase |
| US4130667A (en) | 1976-01-12 | 1978-12-19 | The Procter & Gamble Company | Dermatological compositions |
| CH632668A5 (de) * | 1977-12-09 | 1982-10-29 | Hoffmann La Roche | Kosmetisches mittel. |
| CA1165240A (en) | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
| FR2503151A1 (fr) * | 1981-04-02 | 1982-10-08 | Morelle Jean | Butyryminoacides soufres. mode de preparation. emploi comme element keratogenique chez l'homme et l'animal et comme agent de fertilisation chez les vegetaux |
| US4421769A (en) | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
| US4552872A (en) | 1983-06-21 | 1985-11-12 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing corticosteroids |
| US4537776A (en) | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
| US4557934A (en) | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US4711780A (en) * | 1984-06-11 | 1987-12-08 | Fahim Mostafa S | Composition and process for promoting epithelial regeneration |
| US4663157A (en) | 1985-02-28 | 1987-05-05 | The Proctor & Gamble Company | Sunscreen compositions |
| GB2180153A (en) * | 1985-09-10 | 1987-03-25 | Rory Ltd | Compositions containing acetylcysteine |
| US4708966A (en) | 1986-06-27 | 1987-11-24 | The Procter & Gamble Company | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation |
| US4960764A (en) | 1987-03-06 | 1990-10-02 | Richardson-Vicks Inc. | Oil-in-water-in-silicone emulsion compositions |
| US4912248A (en) | 1987-05-18 | 1990-03-27 | The Procter & Gamble Company | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation |
| US4847071A (en) | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent |
| US4847069A (en) | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising sorbohydroxamic acid and an anti-inflammatory agent |
| IL95393A0 (en) * | 1989-08-18 | 1991-06-30 | John Morris Co | Odor-masked and stabilized compositions for treating keratinous tissue,skin conditions,and promoting wound healing |
| FR2666226B1 (fr) * | 1990-08-30 | 1994-10-28 | Jean Noel Thorel | Composition protectrice de la peau. |
| US5404687A (en) | 1991-04-24 | 1995-04-11 | Avco Corporation | Intumescent fireproofing panel system |
| EP0529130A1 (en) | 1991-08-28 | 1993-03-03 | International Business Machines Corporation | Expert system with explanation system |
-
1992
- 1992-08-25 TW TW081106699A patent/TW222591B/zh active
- 1992-08-27 AU AU25443/92A patent/AU657362B2/en not_active Ceased
- 1992-08-27 BR BR9206424A patent/BR9206424A/pt not_active Application Discontinuation
- 1992-08-27 DE DE69212320T patent/DE69212320T2/de not_active Expired - Fee Related
- 1992-08-27 WO PCT/US1992/007287 patent/WO1993004669A1/en active IP Right Grant
- 1992-08-27 HK HK98105704A patent/HK1006419A1/en not_active IP Right Cessation
- 1992-08-27 FI FI940907A patent/FI940907A7/fi unknown
- 1992-08-27 HU HU9400585A patent/HUT67820A/hu unknown
- 1992-08-27 CA CA002116234A patent/CA2116234C/en not_active Expired - Fee Related
- 1992-08-27 RU RU94015599/14A patent/RU94015599A/ru unknown
- 1992-08-27 CZ CS94455A patent/CZ45594A3/cs unknown
- 1992-08-27 SK SK229-94A patent/SK22994A3/sk unknown
- 1992-08-27 EP EP92919202A patent/EP0601088B1/en not_active Expired - Lifetime
- 1992-08-27 ES ES92919202T patent/ES2090684T3/es not_active Expired - Lifetime
- 1992-08-27 AT AT92919202T patent/ATE140385T1/de not_active IP Right Cessation
- 1992-08-27 EP EP95119024A patent/EP0734718A3/en not_active Withdrawn
- 1992-08-27 JP JP5505300A patent/JPH06510542A/ja active Pending
- 1992-08-28 PT PT100828A patent/PT100828A/pt not_active Application Discontinuation
- 1992-08-28 MA MA22923A patent/MA22633A1/fr unknown
- 1992-08-29 CN CN92111211.4A patent/CN1072842A/zh active Pending
- 1992-08-31 MX MX9205005A patent/MX9205005A/es unknown
-
1994
- 1994-02-24 NO NO940638A patent/NO940638D0/no unknown
-
1996
- 1996-09-02 GR GR960402271T patent/GR3020921T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1072842A (zh) | 1993-06-09 |
| CA2116234A1 (en) | 1993-03-18 |
| SK22994A3 (en) | 1994-12-07 |
| EP0734718A2 (en) | 1996-10-02 |
| DE69212320T2 (de) | 1997-03-06 |
| MX9205005A (es) | 1993-05-01 |
| ATE140385T1 (de) | 1996-08-15 |
| HUT67820A (en) | 1995-05-29 |
| WO1993004669A1 (en) | 1993-03-18 |
| FI940907A0 (fi) | 1994-02-25 |
| EP0734718A3 (en) | 2001-11-14 |
| PT100828A (pt) | 1993-10-29 |
| JPH06510542A (ja) | 1994-11-24 |
| CA2116234C (en) | 1998-02-10 |
| NO940638D0 (no) | 1994-02-24 |
| DE69212320D1 (de) | 1996-08-22 |
| NO940638L (enrdf_load_stackoverflow) | 1994-05-02 |
| EP0601088A1 (en) | 1994-06-15 |
| TW222591B (enrdf_load_stackoverflow) | 1994-04-21 |
| MA22633A1 (fr) | 1993-04-01 |
| GR3020921T3 (en) | 1996-12-31 |
| BR9206424A (pt) | 1995-10-17 |
| HU9400585D0 (en) | 1994-05-30 |
| AU657362B2 (en) | 1995-03-09 |
| FI940907L (fi) | 1994-04-25 |
| AU2544392A (en) | 1993-04-05 |
| RU94015599A (ru) | 1996-04-20 |
| FI940907A7 (fi) | 1994-04-25 |
| HK1006419A1 (en) | 1999-02-26 |
| EP0601088B1 (en) | 1996-07-17 |
| ES2090684T3 (es) | 1996-10-16 |
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