CZ418597A3 - 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně - Google Patents
1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně Download PDFInfo
- Publication number
- CZ418597A3 CZ418597A3 CZ974185A CZ418597A CZ418597A3 CZ 418597 A3 CZ418597 A3 CZ 418597A3 CZ 974185 A CZ974185 A CZ 974185A CZ 418597 A CZ418597 A CZ 418597A CZ 418597 A3 CZ418597 A3 CZ 418597A3
- Authority
- CZ
- Czechia
- Prior art keywords
- defined above
- ethyl
- isochroman
- alkyl
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74195P | 1995-06-30 | 1995-06-30 | |
US1123496P | 1996-02-06 | 1996-02-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CZ418597A3 true CZ418597A3 (cs) | 1998-06-17 |
Family
ID=26668092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CZ974185A CZ418597A3 (cs) | 1995-06-30 | 1996-06-07 | 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0836599A1 (de) |
JP (1) | JPH11509532A (de) |
AU (1) | AU6252296A (de) |
BR (1) | BR9609631A (de) |
CA (1) | CA2225282A1 (de) |
CZ (1) | CZ418597A3 (de) |
FI (1) | FI974640A (de) |
MX (1) | MX9710260A (de) |
NO (1) | NO976112L (de) |
PL (1) | PL324319A1 (de) |
SK (1) | SK164297A3 (de) |
WO (1) | WO1997002259A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2370270A (en) * | 2000-12-20 | 2002-06-26 | Lilly Co Eli | Pharmaceutical compounds |
US7335660B2 (en) | 2001-12-19 | 2008-02-26 | Eli Lilly And Company | Isochroman compounds for treatment of CNS disorders |
GB0130339D0 (en) * | 2001-12-19 | 2002-02-06 | Lilly Co Eli | Isochroman compounds |
US7110576B2 (en) | 2002-12-30 | 2006-09-19 | Pitney Bowes Inc. | System and method for authenticating a mailpiece sender |
AU2005238179B2 (en) | 2004-05-05 | 2010-08-26 | F. Hoffmann-La Roche Ag | Arylsulfonyl benzodioxanes useful for modulating the 5-HT6 receptor, the 5-HT2A receptor or both |
WO2006066756A1 (en) | 2004-12-21 | 2006-06-29 | F. Hoffmann-La Roche Ag | Chroman derivatives and uses thereof in the treatment of cns disorders |
BRPI0515835A (pt) | 2004-12-21 | 2008-08-12 | Hoffmann La Roche | derivados de tetralina e de indano e seus usos |
BRPI0516381A (pt) | 2004-12-21 | 2008-09-02 | Hoffmann La Roche | derivados de cromano e seu uso como ligandos de receptor de 5-ht |
DE602005009977D1 (de) | 2004-12-21 | 2008-11-06 | Hoffmann La Roche | Tetralin- und indanderivate und deren anwendungen als 5-ht-antagonisten |
ATE455755T1 (de) | 2004-12-21 | 2010-02-15 | Hoffmann La Roche | Tetralin- und indanderivate und deren anwendungen |
JP2009514828A (ja) | 2005-11-03 | 2009-04-09 | エフ.ホフマン−ラ ロシュ アーゲー | 5−ht6阻害剤としてのアリールスルホニルクロマン類、タンパク質キナーゼ阻害剤としてのインドリルマレイミド誘導体 |
JP2009541248A (ja) | 2006-06-20 | 2009-11-26 | エフ.ホフマン−ラ ロシュ アーゲー | アリールスルホンアミジルテトラリン誘導体及びそれらの使用 |
EP2035370A2 (de) | 2006-06-20 | 2009-03-18 | F. Hoffmann-Roche AG | Tetralin- und indanderivate und ihre verwendung |
EP2041079A1 (de) | 2006-06-20 | 2009-04-01 | F. Hoffmann-Roche AG | Arylsulfonylnaphthalinderivate und anwendungen davon |
JP2010229128A (ja) * | 2009-03-05 | 2010-10-14 | Sumitomo Chemical Co Ltd | ハロゲン置換テレフタル酸ジアミド化合物、その製造方法及び該化合物を用いたハロゲン置換ベンゼンジメタノールの製造方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
JP3773255B2 (ja) * | 1993-12-28 | 2006-05-10 | ファルマシア・アンド・アップジョン・カンパニー | Cnsおよび心血管系疾患治療用複素環化合物 |
-
1996
- 1996-06-07 PL PL96324319A patent/PL324319A1/xx unknown
- 1996-06-07 CZ CZ974185A patent/CZ418597A3/cs unknown
- 1996-06-07 SK SK1642-97A patent/SK164297A3/sk unknown
- 1996-06-07 BR BR9609631A patent/BR9609631A/pt not_active Application Discontinuation
- 1996-06-07 CA CA002225282A patent/CA2225282A1/en not_active Abandoned
- 1996-06-07 JP JP9505135A patent/JPH11509532A/ja active Pending
- 1996-06-07 AU AU62522/96A patent/AU6252296A/en not_active Abandoned
- 1996-06-07 MX MX9710260A patent/MX9710260A/es unknown
- 1996-06-07 EP EP96921264A patent/EP0836599A1/de not_active Withdrawn
- 1996-06-07 WO PCT/US1996/008681 patent/WO1997002259A1/en not_active Application Discontinuation
-
1997
- 1997-12-29 NO NO976112A patent/NO976112L/no unknown
- 1997-12-30 FI FI974640A patent/FI974640A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
BR9609631A (pt) | 1999-03-02 |
NO976112L (no) | 1998-03-02 |
PL324319A1 (en) | 1998-05-25 |
FI974640A0 (fi) | 1997-12-30 |
MX9710260A (es) | 1998-03-29 |
NO976112D0 (no) | 1997-12-29 |
JPH11509532A (ja) | 1999-08-24 |
SK164297A3 (en) | 1998-09-09 |
AU6252296A (en) | 1997-02-05 |
EP0836599A1 (de) | 1998-04-22 |
FI974640A (fi) | 1997-12-30 |
WO1997002259A1 (en) | 1997-01-23 |
CA2225282A1 (en) | 1997-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PD00 | Pending as of 2000-06-30 in czech republic |