NO976112L - 1,6-disubstituerte isokromaner for behandling av migrene - Google Patents

1,6-disubstituerte isokromaner for behandling av migrene

Info

Publication number
NO976112L
NO976112L NO976112A NO976112A NO976112L NO 976112 L NO976112 L NO 976112L NO 976112 A NO976112 A NO 976112A NO 976112 A NO976112 A NO 976112A NO 976112 L NO976112 L NO 976112L
Authority
NO
Norway
Prior art keywords
treatment
isochromes
disubstituted
migraine
useful
Prior art date
Application number
NO976112A
Other languages
English (en)
Other versions
NO976112D0 (no
Inventor
Michael D Ennis
Ruth E Tenbrink
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO976112D0 publication Critical patent/NO976112D0/no
Publication of NO976112L publication Critical patent/NO976112L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Foreliggende oppfinnelse angår 1,6-disubstituerte isokromaner av formel (I) og aromatiske, bisykliske aminer (ABA) som er anvendbare for behandling av hodepine, spesielt migrene og klase- hodepine, og også anvendbare som anti- psykotiske midler og for behandling av andre CNS og/eller kardiovaskulære syk- dommer, og som analgetiske midler.
NO976112A 1995-06-30 1997-12-29 1,6-disubstituerte isokromaner for behandling av migrene NO976112L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74195P 1995-06-30 1995-06-30
US1123496P 1996-02-06 1996-02-06
PCT/US1996/008681 WO1997002259A1 (en) 1995-06-30 1996-06-07 1,6-disubstituted isochromans for treatment of migraine headaches

Publications (2)

Publication Number Publication Date
NO976112D0 NO976112D0 (no) 1997-12-29
NO976112L true NO976112L (no) 1998-03-02

Family

ID=26668092

Family Applications (1)

Application Number Title Priority Date Filing Date
NO976112A NO976112L (no) 1995-06-30 1997-12-29 1,6-disubstituerte isokromaner for behandling av migrene

Country Status (12)

Country Link
EP (1) EP0836599A1 (no)
JP (1) JPH11509532A (no)
AU (1) AU6252296A (no)
BR (1) BR9609631A (no)
CA (1) CA2225282A1 (no)
CZ (1) CZ418597A3 (no)
FI (1) FI974640A0 (no)
MX (1) MX9710260A (no)
NO (1) NO976112L (no)
PL (1) PL324319A1 (no)
SK (1) SK164297A3 (no)
WO (1) WO1997002259A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2370270A (en) * 2000-12-20 2002-06-26 Lilly Co Eli Pharmaceutical compounds
GB0130339D0 (en) * 2001-12-19 2002-02-06 Lilly Co Eli Isochroman compounds
US7335660B2 (en) 2001-12-19 2008-02-26 Eli Lilly And Company Isochroman compounds for treatment of CNS disorders
US7110576B2 (en) 2002-12-30 2006-09-19 Pitney Bowes Inc. System and method for authenticating a mailpiece sender
CN100540546C (zh) 2004-05-05 2009-09-16 弗·哈夫曼-拉罗切有限公司 用于调节5-ht6受体、5-ht2a受体或两者的芳基磺酰基苯并二烷
EP1831189B1 (en) 2004-12-21 2009-11-11 F. Hoffmann-Roche AG Tetralin and indane derivatives and uses thereof
BRPI0515860B8 (pt) 2004-12-21 2021-05-25 Hoffmann La Roche derivados de tetralin e indano, seus usos, e composição farmacêutica
EP1831191B1 (en) 2004-12-21 2008-05-21 F. Hoffmann-La Roche AG Chroman derivatives and their use as 5-ht receptor ligands
CN101119989B (zh) 2004-12-21 2010-06-09 弗·哈夫曼-拉罗切有限公司 色满衍生物及其在治疗cns疾病中的用途
DE602005009977D1 (de) 2004-12-21 2008-11-06 Hoffmann La Roche Tetralin- und indanderivate und deren anwendungen als 5-ht-antagonisten
NZ567285A (en) 2005-11-03 2010-06-25 Hoffmann La Roche Arylsulfonylchromans as 5-HT6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors
WO2007147771A2 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Tetralin and indane derivatives and uses thereof
JP2009541249A (ja) 2006-06-20 2009-11-26 エフ．ホフマン−ラ ロシュ アーゲー アリールスルホニルナフタレン誘導体およびその使用
BRPI0713502A2 (pt) 2006-06-20 2012-03-13 F. Hoffmann-La Roche Ag derivados de tetralina de arilsulfonamidil e empregos destes
KR20110125258A (ko) * 2009-03-05 2011-11-18 스미또모 가가꾸 가부시끼가이샤 할로겐 치환 벤젠디메탄올의 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552004A (en) * 1976-05-26 1979-09-05 Takeda Chemical Industries Ltd Isochroman derivatives
CA2176722A1 (en) * 1993-12-28 1995-07-06 Ruth E. Ten Brink Heterocyclic compounds for the treatment of cns and cardiovascular disorders

Also Published As

Publication number Publication date
BR9609631A (pt) 1999-03-02
NO976112D0 (no) 1997-12-29
EP0836599A1 (en) 1998-04-22
AU6252296A (en) 1997-02-05
FI974640A (fi) 1997-12-30
PL324319A1 (en) 1998-05-25
SK164297A3 (en) 1998-09-09
MX9710260A (es) 1998-03-29
FI974640A0 (fi) 1997-12-30
WO1997002259A1 (en) 1997-01-23
CZ418597A3 (cs) 1998-06-17
CA2225282A1 (en) 1997-01-23
JPH11509532A (ja) 1999-08-24

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