SK164297A3 - 1,6-disubstituted isochromans for treatment of migraine headaches - Google Patents
1,6-disubstituted isochromans for treatment of migraine headaches Download PDFInfo
- Publication number
- SK164297A3 SK164297A3 SK1642-97A SK164297A SK164297A3 SK 164297 A3 SK164297 A3 SK 164297A3 SK 164297 A SK164297 A SK 164297A SK 164297 A3 SK164297 A3 SK 164297A3
- Authority
- SK
- Slovakia
- Prior art keywords
- ethyl
- defined above
- isochroman
- alkyl
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74195P | 1995-06-30 | 1995-06-30 | |
US1123496P | 1996-02-06 | 1996-02-06 | |
PCT/US1996/008681 WO1997002259A1 (en) | 1995-06-30 | 1996-06-07 | 1,6-disubstituted isochromans for treatment of migraine headaches |
Publications (1)
Publication Number | Publication Date |
---|---|
SK164297A3 true SK164297A3 (en) | 1998-09-09 |
Family
ID=26668092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK1642-97A SK164297A3 (en) | 1995-06-30 | 1996-06-07 | 1,6-disubstituted isochromans for treatment of migraine headaches |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0836599A1 (no) |
JP (1) | JPH11509532A (no) |
AU (1) | AU6252296A (no) |
BR (1) | BR9609631A (no) |
CA (1) | CA2225282A1 (no) |
CZ (1) | CZ418597A3 (no) |
FI (1) | FI974640A (no) |
MX (1) | MX9710260A (no) |
NO (1) | NO976112L (no) |
PL (1) | PL324319A1 (no) |
SK (1) | SK164297A3 (no) |
WO (1) | WO1997002259A1 (no) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2370270A (en) * | 2000-12-20 | 2002-06-26 | Lilly Co Eli | Pharmaceutical compounds |
US7335660B2 (en) | 2001-12-19 | 2008-02-26 | Eli Lilly And Company | Isochroman compounds for treatment of CNS disorders |
GB0130339D0 (en) * | 2001-12-19 | 2002-02-06 | Lilly Co Eli | Isochroman compounds |
US7110576B2 (en) | 2002-12-30 | 2006-09-19 | Pitney Bowes Inc. | System and method for authenticating a mailpiece sender |
ES2338668T3 (es) | 2004-05-05 | 2010-05-11 | F. Hoffmann-La Roche Ag | Arilsulfonil benzodioxanos utiles para la modulacion del receptor 5-ht6 y del receptor 5-ht2a o ambos. |
DK1831159T3 (da) | 2004-12-21 | 2010-03-22 | Hoffmann La Roche | Tetralin og indanderivater samt anvendelser deraf |
RU2388748C2 (ru) | 2004-12-21 | 2010-05-10 | Ф. Хоффманн-Ля Рош Аг | Производные тетралина и индана и их применения в качестве антагонистов 5-нт |
WO2006066756A1 (en) | 2004-12-21 | 2006-06-29 | F. Hoffmann-La Roche Ag | Chroman derivatives and uses thereof in the treatment of cns disorders |
AU2005318596B2 (en) | 2004-12-21 | 2010-12-23 | F. Hoffmann-La Roche Ag | Chroman derivatives and their use as 5-HT receptor ligands |
KR100899061B1 (ko) | 2004-12-21 | 2009-05-25 | 에프. 호프만-라 로슈 아게 | 테트랄린 및 인단 유도체 및 이의 용도 |
CN101300246A (zh) | 2005-11-03 | 2008-11-05 | 弗·哈夫曼-拉罗切有限公司 | 作为5-ht6抑制剂的芳基磺酰基色满类化合物作为蛋白激酶抑制剂的吲哚基马来酰亚胺衍生物 |
BRPI0713736A2 (pt) | 2006-06-20 | 2014-11-18 | Hoffmann La Roche | Derivados de tetralina e indano e emprego destes |
BRPI0713742A2 (pt) | 2006-06-20 | 2013-02-13 | Hoffmann La Roche | derivados de arilsulfonila naftaleno e usos destes |
KR101064001B1 (ko) | 2006-06-20 | 2011-09-08 | 에프. 호프만-라 로슈 아게 | 아릴설폰아미딜 테트랄린 유도체 및 이의 용도 |
EP2404897A4 (en) * | 2009-03-05 | 2014-02-26 | Sumitomo Chemical Co | PROCESS FOR PREPARING HALOGEN-SUBSTITUTED BENCHENETIMETHANOL |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
DK0737189T3 (da) * | 1993-12-28 | 2000-03-06 | Upjohn Co | Heterocycliske forbindelser til behandling af CNS-forstyrrelser og cardiovaskulære forstyrrelser |
-
1996
- 1996-06-07 PL PL96324319A patent/PL324319A1/xx unknown
- 1996-06-07 CA CA002225282A patent/CA2225282A1/en not_active Abandoned
- 1996-06-07 BR BR9609631A patent/BR9609631A/pt not_active Application Discontinuation
- 1996-06-07 JP JP9505135A patent/JPH11509532A/ja active Pending
- 1996-06-07 MX MX9710260A patent/MX9710260A/es unknown
- 1996-06-07 SK SK1642-97A patent/SK164297A3/sk unknown
- 1996-06-07 CZ CZ974185A patent/CZ418597A3/cs unknown
- 1996-06-07 EP EP96921264A patent/EP0836599A1/en not_active Withdrawn
- 1996-06-07 AU AU62522/96A patent/AU6252296A/en not_active Abandoned
- 1996-06-07 WO PCT/US1996/008681 patent/WO1997002259A1/en not_active Application Discontinuation
-
1997
- 1997-12-29 NO NO976112A patent/NO976112L/no unknown
- 1997-12-30 FI FI974640A patent/FI974640A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
MX9710260A (es) | 1998-03-29 |
FI974640A0 (fi) | 1997-12-30 |
BR9609631A (pt) | 1999-03-02 |
JPH11509532A (ja) | 1999-08-24 |
NO976112D0 (no) | 1997-12-29 |
PL324319A1 (en) | 1998-05-25 |
FI974640A (fi) | 1997-12-30 |
NO976112L (no) | 1998-03-02 |
EP0836599A1 (en) | 1998-04-22 |
CA2225282A1 (en) | 1997-01-23 |
CZ418597A3 (cs) | 1998-06-17 |
WO1997002259A1 (en) | 1997-01-23 |
AU6252296A (en) | 1997-02-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7456164B2 (en) | 3- or 4-monosubtituted phenol and thiophenol derivatives useful as H3 ligands | |
AU2013254657B2 (en) | Novel compounds | |
EP1951660B1 (en) | Histamine-3 receptor antagonists | |
US6498168B2 (en) | Muscarinic antagonists | |
US7951821B2 (en) | N-[phenyl(piperidin-2-yl)methyl]benzamide derivatives, preparation thereof, and use thereof in therapy | |
US6635630B2 (en) | Selective neurokinin antagonists | |
NL1028968C2 (nl) | 3- of 4-monogesubstitueerde fenol- en thiofenolderivaten die als H3-liganden bruikbaar zijn. | |
JP5189110B2 (ja) | ドーパミンd4受容体拮抗剤であるピペラジニル−プロピル−ピラゾール誘導体及びそれを含む医薬組成物 | |
TW536537B (en) | Benzoxazine antimicrobial agents | |
SK164297A3 (en) | 1,6-disubstituted isochromans for treatment of migraine headaches | |
US20030236250A1 (en) | Cyclohexane derivatives and their use as therapeutic agents | |
EP1499589A1 (fr) | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique | |
MXPA02006017A (es) | Antagonistas de neuroquinina selectivos. | |
US20090124624A1 (en) | Substituted 1-aminophthalazine derivatives, preparation thereof and therapeutic application thereof | |
JPWO2005037269A1 (ja) | 新規ピペリジン誘導体 | |
JP2001525406A (ja) | 新規な化合物 | |
WO2000066551A1 (fr) | Composes d'amides cycliques, leurs procedes de preparation et d'utilisation | |
JP5250627B2 (ja) | 新規化合物 | |
RU2158264C2 (ru) | 3-азетидинилалкилпиперидины или пирролидины в качестве антагонистов тахикинина, способы их получения, промежуточные соединения, фармацевтическая композиция на их основе и способ лечения | |
US7122677B2 (en) | NK1 antagonists | |
US10017480B2 (en) | Compounds having a selective PDE4D inhibiting activity | |
EP3055293A1 (en) | Diarylalkylamine rev-erb antagonists and their use as medicaments | |
HU225747B1 (en) | New benzenesulphonamide compounds, their preparation thereof and pharmaceutical compositions containing them | |
EP2401268B1 (en) | Oxyindole derivatives with motilin receptor agonistic activity | |
OA11235A (en) | Quatenary ammonium compounds as tachykinin antagonists |