CZ302483B6 - Vodný roztok s obsahem epinastinu - Google Patents

Vodný roztok s obsahem epinastinu Download PDF

Info

Publication number
CZ302483B6
CZ302483B6 CZ20021956A CZ20021956A CZ302483B6 CZ 302483 B6 CZ302483 B6 CZ 302483B6 CZ 20021956 A CZ20021956 A CZ 20021956A CZ 20021956 A CZ20021956 A CZ 20021956A CZ 302483 B6 CZ302483 B6 CZ 302483B6
Authority
CZ
Czechia
Prior art keywords
use according
optionally
buffer
sodium
adjusting
Prior art date
Application number
CZ20021956A
Other languages
Czech (cs)
English (en)
Other versions
CZ20021956A3 (cs
Inventor
Duschler@Gerold
Trach@Volker
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7928843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CZ302483(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of CZ20021956A3 publication Critical patent/CZ20021956A3/cs
Publication of CZ302483B6 publication Critical patent/CZ302483B6/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F01—MACHINES OR ENGINES IN GENERAL; ENGINE PLANTS IN GENERAL; STEAM ENGINES
    • F01L—CYCLICALLY OPERATING VALVES FOR MACHINES OR ENGINES
    • F01L9/00—Valve-gear or valve arrangements actuated non-mechanically
    • F01L9/20—Valve-gear or valve arrangements actuated non-mechanically by electric means
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)
CZ20021956A 1999-11-12 2000-10-14 Vodný roztok s obsahem epinastinu CZ302483B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19954516A DE19954516A1 (de) 1999-11-12 1999-11-12 Epinastin-haltige Lösungen

Publications (2)

Publication Number Publication Date
CZ20021956A3 CZ20021956A3 (cs) 2002-08-14
CZ302483B6 true CZ302483B6 (cs) 2011-06-08

Family

ID=7928843

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20021956A CZ302483B6 (cs) 1999-11-12 2000-10-14 Vodný roztok s obsahem epinastinu

Country Status (40)

Country Link
US (6) US20030050303A1 (pt)
EP (1) EP1231920B1 (pt)
JP (1) JP2003514021A (pt)
KR (1) KR100758842B1 (pt)
CN (1) CN1292752C (pt)
AR (1) AR026424A1 (pt)
AT (1) ATE353218T1 (pt)
AU (2) AU784017B2 (pt)
BG (1) BG65775B1 (pt)
BR (1) BR0015477A (pt)
CA (1) CA2391076C (pt)
CO (1) CO5251448A1 (pt)
CY (1) CY1106375T1 (pt)
CZ (1) CZ302483B6 (pt)
DE (2) DE19954516A1 (pt)
DK (1) DK1231920T3 (pt)
EA (1) EA006937B1 (pt)
EE (1) EE05395B1 (pt)
ES (1) ES2281359T3 (pt)
HK (1) HK1052303B (pt)
HR (1) HRP20020404B1 (pt)
HU (1) HU229502B1 (pt)
IL (2) IL149501A0 (pt)
ME (1) MEP36708A (pt)
MX (1) MXPA02004556A (pt)
MY (1) MY130441A (pt)
NO (1) NO329417B1 (pt)
NZ (1) NZ519425A (pt)
PE (1) PE20010826A1 (pt)
PL (1) PL198879B1 (pt)
PT (1) PT1231920E (pt)
RS (1) RS50173B (pt)
SA (1) SA01210658B1 (pt)
SI (1) SI1231920T1 (pt)
SK (1) SK287343B6 (pt)
TR (1) TR200201270T2 (pt)
TW (1) TWI225401B (pt)
UA (1) UA74563C2 (pt)
WO (1) WO2001035962A1 (pt)
ZA (1) ZA200203683B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
JP2006501211A (ja) * 2002-08-02 2006-01-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング エピナスチン、プソイドエフェドリン及びメチルエフェドリンの組み合せを含有する医薬組成物
EP1468696A1 (en) * 2003-04-17 2004-10-20 Boehringer Ingelheim International GmbH Combinations of epinastine and antiphlogisitcs as new pharmaceutical compositions for the treatment of skin diseases
US20040247686A1 (en) * 2003-04-04 2004-12-09 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising epinastine for the treatment of skin diseases
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
CN101217948A (zh) * 2005-07-08 2008-07-09 千寿制药株式会社 包含依匹那丁的透皮吸收眼科制剂
US7378082B1 (en) 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
WO2008098122A2 (en) * 2007-02-08 2008-08-14 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
US20080194544A1 (en) * 2007-02-08 2008-08-14 Ramesh Krishnamoorthy Aqueous formulations of epinastine for treating allergic rhinitis
EP2464387A4 (en) * 2009-08-12 2013-05-15 Seros Medical Llc DEUTERATED WATER SOLUTION AND RIBOFLAVIN FOR EXTENDED OXYGEN SINGULET LIFETIME IN THE TREATMENT OF OCULAR TISSUE AND METHOD OF USE
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
EA201791321A1 (ru) * 2012-12-19 2018-04-30 Саркоуд Байосайенс Инк. Составы ингибитора lfa-1
CN104491876A (zh) * 2014-12-23 2015-04-08 中国药科大学 含玻璃酸钠的依匹斯汀滴眼液及其制备方法
ITUB20153950A1 (it) * 2015-09-28 2017-03-28 Tred Srl Dispositivo nasale in grado di attivare il riflesso rino-palatale per l'igienizzazione rinofaringea
JP6134853B1 (ja) * 2016-10-28 2017-05-24 参天製薬株式会社 エピナスチン含有点眼液
JP6635974B2 (ja) * 2017-04-24 2020-01-29 参天製薬株式会社 エピナスチン含有点眼液
WO2018203424A1 (ja) * 2017-05-01 2018-11-08 参天製薬株式会社 点眼剤
JP2019108320A (ja) * 2018-10-31 2019-07-04 参天製薬株式会社 ソフトコンタクトレンズの変質を抑制する眼科用組成物
JP6736752B2 (ja) * 2019-12-17 2020-08-05 参天製薬株式会社 エピナスチン含有点眼液
JP6963651B2 (ja) 2020-04-16 2021-11-10 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP7118579B1 (ja) 2020-04-16 2022-08-16 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP2020169213A (ja) * 2020-07-15 2020-10-15 参天製薬株式会社 エピナスチン含有点眼液
CN115448927A (zh) * 2022-10-20 2022-12-09 重庆瑞泊莱医药科技有限公司 一种氢溴酸依匹斯汀晶型ii及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS221288B2 (en) * 1980-03-08 1983-04-29 Boehringer Sohn Ingelheim Method of making the heterocyclic compounds
WO1997017971A1 (de) * 1995-11-14 1997-05-22 Boehringer Ingelheim Kg Verwendung von epinastin für die behandlung von schmerzen
EP0903151A1 (en) * 1997-09-22 1999-03-24 ASTA Medica Aktiengesellschaft Use of combinations comprising non-sedating antihistamines and alpha-adrenergic drugs for the topical treatment of rhinitis/conjunctivitis and cold, cold-like and/or flu symptoms

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US228359A (en) * 1880-06-01 jones
US151541A (en) * 1874-06-02 Improvement in hay-loaders
US8632A (en) * 1852-01-06 George hess
US203021A (en) * 1878-04-30 Improvement in side-bar wagons
US181478A (en) * 1876-08-22 Improvement in water-wheels
US215396A (en) * 1879-05-13 Improvement in loom-temples
US104017A (en) * 1870-06-07 Improvement in embroidering attachment for sewing-machines
DE4102148A1 (de) * 1991-01-25 1992-07-30 Boehringer Ingelheim Kg Verfahren zur herstellung von 3-amino-9,13b-dihydro-1h-dibenz-(c,f)imidazol(1,5-a)azepin-hydrochlorid
US5668133A (en) * 1992-12-09 1997-09-16 Alcon Laboratories, Inc. Ophthalmic compositions comprising emedastine and methods for their use
EP0835098B1 (de) * 1995-06-27 2002-09-04 Boehringer Ingelheim Pharma KG Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole
JP3124041B2 (ja) * 1996-08-30 2001-01-15 京都薬品工業株式会社 アレルギー性皮膚炎治療剤
US20030215396A1 (en) * 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
US6649602B1 (en) * 1999-11-18 2003-11-18 Alcon, Inc. Use of an H1 antagonist and a safe steroid to treat eye conditions
DE19958460A1 (de) * 1999-12-03 2001-06-07 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Epinastine-Hydrochlorid in der hochschmelzenden Kristallmodifikation
FR2803520B1 (fr) * 2000-01-12 2002-09-20 Ceva Sante Animale Procede pour augmenter la production d'oeufs et consolider la coquille des oeufs chez les volailles
US20020094345A1 (en) * 2000-10-06 2002-07-18 Sara Abelaira Pharmaceutical compositions containing epinastine and pseudoephedrine
US20020137764A1 (en) * 2000-10-31 2002-09-26 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
US20020151541A1 (en) * 2000-10-31 2002-10-17 Michel Pairet Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
DE10119718A1 (de) * 2001-04-21 2002-10-31 Boehringer Ingelheim Pharma Verfahren zur kontinuierlichen Herstellung inhalierfähiger Arzneistoffe, Vorrichtung zur Durchführung des Verfahrens und nach diesem Verfahren hergestellter Arzneistoff
WO2002098112A2 (en) * 2001-05-29 2002-12-05 Transchip, Inc. Patent application cmos imager for cellular applications and methods of using such
US20030104017A1 (en) * 2001-10-26 2003-06-05 Boehringer Ingelheim International Gmbh Epinastine formulation for oral administration
EP1350512A1 (en) * 2002-04-03 2003-10-08 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Combinations of epinastine, belladonna and pseudoephedrine as new pharmaceutical formulations
US6863848B2 (en) * 2002-08-30 2005-03-08 Signet Armorlite, Inc. Methods for preparing composite photochromic ophthalmic lenses
JP2007145316A (ja) * 2005-10-27 2007-06-14 Nissan Motor Co Ltd 遮光装置とサンバイザーとサンルーフユニット

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS221288B2 (en) * 1980-03-08 1983-04-29 Boehringer Sohn Ingelheim Method of making the heterocyclic compounds
WO1997017971A1 (de) * 1995-11-14 1997-05-22 Boehringer Ingelheim Kg Verwendung von epinastin für die behandlung von schmerzen
EP0903151A1 (en) * 1997-09-22 1999-03-24 ASTA Medica Aktiengesellschaft Use of combinations comprising non-sedating antihistamines and alpha-adrenergic drugs for the topical treatment of rhinitis/conjunctivitis and cold, cold-like and/or flu symptoms

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Tadashi Kohyama a spol. : A Novel Antiallergic Drug Epinastine Inhibits IL-8 Release from Human Eosinophils, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 230, str. 125-128, 1997 *

Also Published As

Publication number Publication date
SI1231920T1 (sl) 2007-06-30
YU33602A (sh) 2005-03-15
SA01210658B1 (ar) 2006-11-05
DK1231920T3 (da) 2007-04-10
MEP36708A (en) 2011-02-10
KR100758842B1 (ko) 2007-09-19
CZ20021956A3 (cs) 2002-08-14
HK1052303B (zh) 2007-04-13
IL149501A0 (en) 2002-11-10
AU784017B2 (en) 2006-01-12
HRP20020404A2 (en) 2004-08-31
HUP0203773A2 (hu) 2003-03-28
DE19954516A1 (de) 2001-05-17
MXPA02004556A (es) 2004-09-10
EP1231920B1 (de) 2007-02-07
US20090239842A1 (en) 2009-09-24
JP2003514021A (ja) 2003-04-15
NO20022201L (no) 2002-05-08
CN1292752C (zh) 2007-01-03
BG106681A (en) 2002-12-29
UA74563C2 (uk) 2006-01-16
BG65775B1 (bg) 2009-11-30
HUP0203773A3 (en) 2005-01-28
NO20022201D0 (no) 2002-05-08
TWI225401B (en) 2004-12-21
EA200200492A1 (ru) 2002-10-31
US20030050303A1 (en) 2003-03-13
AR026424A1 (es) 2003-02-12
EA006937B1 (ru) 2006-06-30
EE05395B1 (et) 2011-04-15
CA2391076A1 (en) 2001-05-25
ES2281359T3 (es) 2007-10-01
US20080009476A1 (en) 2008-01-10
AU1138101A (en) 2001-05-30
EP1231920A1 (de) 2002-08-21
RS50173B (sr) 2009-05-06
NO329417B1 (no) 2010-10-18
SK8302002A3 (en) 2002-09-10
US20070185082A1 (en) 2007-08-09
US20070197503A1 (en) 2007-08-23
NZ519425A (en) 2004-04-30
PL198879B1 (pl) 2008-07-31
CA2391076C (en) 2008-06-17
DE50014041D1 (de) 2007-03-22
US20050288274A1 (en) 2005-12-29
KR20020050273A (ko) 2002-06-26
AU2006201541A1 (en) 2006-05-11
CN1390129A (zh) 2003-01-08
CO5251448A1 (es) 2003-02-28
ZA200203683B (en) 2003-09-03
HK1052303A1 (en) 2003-09-11
US7429602B2 (en) 2008-09-30
CY1106375T1 (el) 2011-10-12
WO2001035962A1 (de) 2001-05-25
HRP20020404B1 (en) 2007-08-31
PE20010826A1 (es) 2001-08-20
TR200201270T2 (tr) 2002-12-23
IL149501A (en) 2012-04-30
ATE353218T1 (de) 2007-02-15
EE200200246A (et) 2003-06-16
SK287343B6 (sk) 2010-07-07
PT1231920E (pt) 2007-03-30
BR0015477A (pt) 2002-06-25
PL364028A1 (en) 2004-11-29
HU229502B1 (en) 2014-01-28
MY130441A (en) 2007-06-29

Similar Documents

Publication Publication Date Title
CZ302483B6 (cs) Vodný roztok s obsahem epinastinu
US6664286B1 (en) Serotonergic 5ht2 agonists for treating glaucoma
US7875271B2 (en) Ophthalmic composition comprising xanthan gum and glucose
JP2015110672A (ja) ビマトプロストおよびブリモニジンの固定用量の組み合わせ
KR100776577B1 (ko) 점안제
AU778148B2 (en) 2-aminotetralin derivatives for the therapy of glaucoma
WO2006053150B1 (en) Pharmaceutical compositions for topical application on the treatment of age-related macular degeneration and ocular hypertension
JP5087233B2 (ja) 角結膜障害の予防または治療剤
EP2762144B1 (en) Combination of hyaluronic acid and flavin adenine dinucleotide for use in inhibiting corneal epithelial cell death

Legal Events

Date Code Title Description
MK4A Patent expired

Effective date: 20201014