PE20010826A1 - Soluciones que contienen epinastina - Google Patents

Soluciones que contienen epinastina

Info

Publication number
PE20010826A1
PE20010826A1 PE2000001201A PE0012012000A PE20010826A1 PE 20010826 A1 PE20010826 A1 PE 20010826A1 PE 2000001201 A PE2000001201 A PE 2000001201A PE 0012012000 A PE0012012000 A PE 0012012000A PE 20010826 A1 PE20010826 A1 PE 20010826A1
Authority
PE
Peru
Prior art keywords
solutions containing
solution
containing epinastine
enanthymers
conjunctivity
Prior art date
Application number
PE2000001201A
Other languages
English (en)
Inventor
Volker Trach
Gerold Duschler
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7928843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20010826(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PE20010826A1 publication Critical patent/PE20010826A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F01MACHINES OR ENGINES IN GENERAL; ENGINE PLANTS IN GENERAL; STEAM ENGINES
    • F01LCYCLICALLY OPERATING VALVES FOR MACHINES OR ENGINES
    • F01L9/00Valve-gear or valve arrangements actuated non-mechanically
    • F01L9/20Valve-gear or valve arrangements actuated non-mechanically by electric means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/0318Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)

Abstract

SE REFIERE A SOLUCIONES ACUOSAS TOPICAS QUE CONTIENE HIDROCLORURO DE EPINASTINA (3-AMINO-9,13b-DIHIDRO-1H-DIBENZO-[c,f]-IMIDAZOL-[1,5-a]AZEPINA, EN FORMA DE RACEMATO, ENANTIOMEROS, SALES DE ADICION DE ACIDOS; EN UNA CONCENTRACION DE 0,005 mg/ml. A 0,5 mg/ml. DE SOLUCION; CARACTERIZADA PORQUE SE AJUSTA A UN VALOR DE pH DE 6,5 A 7,2 CON UN TAMPON; ADEMAS CONTIENE UN AGENTE DE CONSERVACION. LA SOLUCION PUEDE SER UTIL PARA LA INHIBICION DE LA AFLUENCIA DE NEUTROFILOS Y EOSINOFILOS EN EL TEJIDO DE LA CONJUNTIVA DEL OJO O EN EL DE LA MUCOSA NASAL
PE2000001201A 1999-11-12 2000-11-10 Soluciones que contienen epinastina PE20010826A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19954516A DE19954516A1 (de) 1999-11-12 1999-11-12 Epinastin-haltige Lösungen

Publications (1)

Publication Number Publication Date
PE20010826A1 true PE20010826A1 (es) 2001-08-20

Family

ID=7928843

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000001201A PE20010826A1 (es) 1999-11-12 2000-11-10 Soluciones que contienen epinastina

Country Status (40)

Country Link
US (6) US20030050303A1 (es)
EP (1) EP1231920B1 (es)
JP (1) JP2003514021A (es)
KR (1) KR100758842B1 (es)
CN (1) CN1292752C (es)
AR (1) AR026424A1 (es)
AT (1) ATE353218T1 (es)
AU (2) AU784017B2 (es)
BG (1) BG65775B1 (es)
BR (1) BR0015477A (es)
CA (1) CA2391076C (es)
CO (1) CO5251448A1 (es)
CY (1) CY1106375T1 (es)
CZ (1) CZ302483B6 (es)
DE (2) DE19954516A1 (es)
DK (1) DK1231920T3 (es)
EA (1) EA006937B1 (es)
EE (1) EE05395B1 (es)
ES (1) ES2281359T3 (es)
HK (1) HK1052303B (es)
HR (1) HRP20020404B1 (es)
HU (1) HU229502B1 (es)
IL (2) IL149501A0 (es)
ME (1) MEP36708A (es)
MX (1) MXPA02004556A (es)
MY (1) MY130441A (es)
NO (1) NO329417B1 (es)
NZ (1) NZ519425A (es)
PE (1) PE20010826A1 (es)
PL (1) PL198879B1 (es)
PT (1) PT1231920E (es)
RS (1) RS50173B (es)
SA (1) SA01210658B1 (es)
SI (1) SI1231920T1 (es)
SK (1) SK287343B6 (es)
TR (1) TR200201270T2 (es)
TW (1) TWI225401B (es)
UA (1) UA74563C2 (es)
WO (1) WO2001035962A1 (es)
ZA (1) ZA200203683B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
BR0313175A (pt) * 2002-08-02 2005-06-14 Boehringer Ingelheim Int Formulações farmacêuticas compreendendo combinações de epinastina, pseudoefedrina e metilefedrina
EP1468696A1 (en) * 2003-04-17 2004-10-20 Boehringer Ingelheim International GmbH Combinations of epinastine and antiphlogisitcs as new pharmaceutical compositions for the treatment of skin diseases
US20040247686A1 (en) * 2003-04-04 2004-12-09 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising epinastine for the treatment of skin diseases
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
KR20080034916A (ko) * 2005-07-08 2008-04-22 센주 세이야꾸 가부시키가이샤 에피나스틴을 포함하는 경피 흡수 안과 제제
WO2008098122A2 (en) * 2007-02-08 2008-08-14 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
US7378082B1 (en) 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
US20080194544A1 (en) * 2007-02-08 2008-08-14 Ramesh Krishnamoorthy Aqueous formulations of epinastine for treating allergic rhinitis
EP2464387A4 (en) * 2009-08-12 2013-05-15 Seros Medical Llc DEUTERATED WATER SOLUTION AND RIBOFLAVIN FOR EXTENDED OXYGEN SINGULET LIFETIME IN THE TREATMENT OF OCULAR TISSUE AND METHOD OF USE
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠(olopatadine)眼用組成物
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
NZ708821A (en) * 2012-12-19 2020-03-27 Novartis Ag Lfa-1 inhibitor formulations
CN104491876A (zh) * 2014-12-23 2015-04-08 中国药科大学 含玻璃酸钠的依匹斯汀滴眼液及其制备方法
ITUB20153950A1 (it) * 2015-09-28 2017-03-28 Tred Srl Dispositivo nasale in grado di attivare il riflesso rino-palatale per l'igienizzazione rinofaringea
JP6134853B1 (ja) * 2016-10-28 2017-05-24 参天製薬株式会社 エピナスチン含有点眼液
JP6635974B2 (ja) * 2017-04-24 2020-01-29 参天製薬株式会社 エピナスチン含有点眼液
WO2018203424A1 (ja) * 2017-05-01 2018-11-08 参天製薬株式会社 点眼剤
JP6736752B2 (ja) * 2019-12-17 2020-08-05 参天製薬株式会社 エピナスチン含有点眼液
JP6963651B2 (ja) * 2020-04-16 2021-11-10 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP7118579B1 (ja) 2020-04-16 2022-08-16 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP2020169213A (ja) * 2020-07-15 2020-10-15 参天製薬株式会社 エピナスチン含有点眼液
CN115448927A (zh) * 2022-10-20 2022-12-09 重庆瑞泊莱医药科技有限公司 一种氢溴酸依匹斯汀晶型ii及其制备方法

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EP1350512A1 (en) * 2002-04-03 2003-10-08 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Combinations of epinastine, belladonna and pseudoephedrine as new pharmaceutical formulations
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Also Published As

Publication number Publication date
YU33602A (sh) 2005-03-15
SI1231920T1 (sl) 2007-06-30
JP2003514021A (ja) 2003-04-15
CY1106375T1 (el) 2011-10-12
PL364028A1 (en) 2004-11-29
NO329417B1 (no) 2010-10-18
US20070197503A1 (en) 2007-08-23
KR100758842B1 (ko) 2007-09-19
ZA200203683B (en) 2003-09-03
HU229502B1 (en) 2014-01-28
BR0015477A (pt) 2002-06-25
RS50173B (sr) 2009-05-06
EE05395B1 (et) 2011-04-15
ES2281359T3 (es) 2007-10-01
US20090239842A1 (en) 2009-09-24
MXPA02004556A (es) 2004-09-10
PT1231920E (pt) 2007-03-30
HK1052303A1 (en) 2003-09-11
EA006937B1 (ru) 2006-06-30
SK287343B6 (sk) 2010-07-07
UA74563C2 (uk) 2006-01-16
CA2391076C (en) 2008-06-17
AU1138101A (en) 2001-05-30
PL198879B1 (pl) 2008-07-31
IL149501A0 (en) 2002-11-10
NO20022201L (no) 2002-05-08
CO5251448A1 (es) 2003-02-28
US20030050303A1 (en) 2003-03-13
US7429602B2 (en) 2008-09-30
HRP20020404A2 (en) 2004-08-31
HUP0203773A2 (hu) 2003-03-28
NO20022201D0 (no) 2002-05-08
TWI225401B (en) 2004-12-21
IL149501A (en) 2012-04-30
DE19954516A1 (de) 2001-05-17
HK1052303B (zh) 2007-04-13
BG106681A (en) 2002-12-29
KR20020050273A (ko) 2002-06-26
EE200200246A (et) 2003-06-16
DE50014041D1 (de) 2007-03-22
MEP36708A (en) 2011-02-10
AU784017B2 (en) 2006-01-12
MY130441A (en) 2007-06-29
DK1231920T3 (da) 2007-04-10
NZ519425A (en) 2004-04-30
BG65775B1 (bg) 2009-11-30
HUP0203773A3 (en) 2005-01-28
EP1231920A1 (de) 2002-08-21
EP1231920B1 (de) 2007-02-07
CZ20021956A3 (cs) 2002-08-14
HRP20020404B1 (en) 2007-08-31
US20070185082A1 (en) 2007-08-09
WO2001035962A1 (de) 2001-05-25
ATE353218T1 (de) 2007-02-15
SA01210658B1 (ar) 2006-11-05
CZ302483B6 (cs) 2011-06-08
US20050288274A1 (en) 2005-12-29
US20080009476A1 (en) 2008-01-10
CA2391076A1 (en) 2001-05-25
CN1390129A (zh) 2003-01-08
AR026424A1 (es) 2003-02-12
EA200200492A1 (ru) 2002-10-31
CN1292752C (zh) 2007-01-03
AU2006201541A1 (en) 2006-05-11
SK8302002A3 (en) 2002-09-10
TR200201270T2 (tr) 2002-12-23

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