CO5271759A1 - Formulacion en solucion que contiene una mezcla de disolventes - Google Patents

Formulacion en solucion que contiene una mezcla de disolventes

Info

Publication number
CO5271759A1
CO5271759A1 CO99065439A CO99065439A CO5271759A1 CO 5271759 A1 CO5271759 A1 CO 5271759A1 CO 99065439 A CO99065439 A CO 99065439A CO 99065439 A CO99065439 A CO 99065439A CO 5271759 A1 CO5271759 A1 CO 5271759A1
Authority
CO
Colombia
Prior art keywords
formulation
solvents
mixture
solution containing
formoterol
Prior art date
Application number
CO99065439A
Other languages
English (en)
Inventor
Dieter Hochrainer
Bernd Zierenberg
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of CO5271759A1 publication Critical patent/CO5271759A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Abstract

Formulación en solución para la terapia por inhalación, que contiene una mezcla de disolventes constituida por etanol y agua, que ha sido ajustada a un valor del pH de aproximadamente 4,5 a 5,5 formoterol disuelto en una concentración de aproximadamente 0,9 a 1,5 mg/ml referido al formoterol, un agente conservante en una cantidad farmacológicamente compatible y Na-EDTA en una cantidad farmacológicamente compatible.
CO99065439A 1998-10-17 1999-10-14 Formulacion en solucion que contiene una mezcla de disolventes CO5271759A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19847969A DE19847969A1 (de) 1998-10-17 1998-10-17 Lagerfähig flüssige Formulierung mit Formoterol

Publications (1)

Publication Number Publication Date
CO5271759A1 true CO5271759A1 (es) 2003-04-30

Family

ID=7884831

Family Applications (2)

Application Number Title Priority Date Filing Date
CO99065439A CO5271759A1 (es) 1998-10-17 1999-10-14 Formulacion en solucion que contiene una mezcla de disolventes
CO99065439D CO5261514A1 (es) 1998-10-17 1999-10-14 Composicion liquida que contiene formoterol

Family Applications After (1)

Application Number Title Priority Date Filing Date
CO99065439D CO5261514A1 (es) 1998-10-17 1999-10-14 Composicion liquida que contiene formoterol

Country Status (14)

Country Link
US (1) US6150418A (es)
AR (1) AR020830A1 (es)
AT (1) ATE218331T1 (es)
AU (1) AU764126B2 (es)
CO (2) CO5271759A1 (es)
DE (1) DE19847969A1 (es)
EG (1) EG23820A (es)
MY (1) MY124329A (es)
PE (1) PE20001226A1 (es)
RS (1) RS49907B (es)
SA (1) SA99200700B1 (es)
TW (1) TW562676B (es)
UA (1) UA71585C2 (es)
ZA (1) ZA200103056B (es)

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DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
US7074388B2 (en) * 1998-12-10 2006-07-11 Kos Life Science, Inc. Water stabilized medicinal aerosol formulation
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
US20100197719A1 (en) * 1999-05-12 2010-08-05 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
US20040002548A1 (en) * 1999-05-12 2004-01-01 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
CN1213732C (zh) * 2000-05-22 2005-08-10 奇斯药制品公司 用于加压计量吸入器的稳定药用溶液制剂
AU2001294808A1 (en) * 2000-09-29 2002-04-08 Board Of Trustees Operating Michigan State University Catecholamine pharmaceutical compositions and methods
ITMI20010428A1 (it) * 2001-03-02 2002-09-02 Chemo Breath S A Composizioni ad uso inalatorio a base di formoterolo
US20020193394A1 (en) * 2001-03-13 2002-12-19 Bernd Disse Compounds for treating inflammatory diseases
DE10111843A1 (de) * 2001-03-13 2002-09-19 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von inflammatorischen Erkrankungen
US6667344B2 (en) * 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DK1273292T3 (da) * 2001-07-02 2004-10-04 Chiesi Farma Spa Optimeret tobramycinformulering til aerosoldannelse
PL209212B1 (pl) * 2002-03-01 2011-08-31 Chiesi Farma Spa Superdrobny preparat formoterolu
WO2003099290A1 (en) * 2002-05-21 2003-12-04 Glaxo Group Limited Pharmaceutical products and methods of manufacture
US20040166065A1 (en) * 2002-08-14 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation comprising an anticholinergic
AU2007231727B2 (en) * 2002-09-03 2010-12-16 Kos Life Sciences, Inc. Water stabilized medicinal aerosol formulation
CA2497845C (en) * 2002-09-06 2012-08-14 Chrysalis Technologies Incorporated Liquid aerosol formulations and aerosol generating devices and methods for generating aerosols
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
DE10345065A1 (de) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
CN100457087C (zh) * 2004-02-27 2009-02-04 奇斯药制品公司 用于加压计量吸入器的稳定的药用溶液制剂
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
KR20070000476A (ko) * 2004-02-27 2007-01-02 키에시 파르마슈티시 엣스. 피. 에이. 압축화 계량된 도스흡입용 안정된 약제용액 제제
EP1742625A1 (en) * 2004-04-05 2007-01-17 Sepracor, Inc. (r,r)-formoterol in combination with other pharmacological agents
ITRM20050022A1 (it) 2005-01-19 2006-07-20 Italchimici S P A Formulazione farmaceutica di una soluzione stabile di glicole propilenico contenente formoterolo per via inalatoria e suo procedimento di preparazione.
WO2009134524A2 (en) * 2008-02-26 2009-11-05 Elevation Pharmaceuticals, Inc. Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
US20100055045A1 (en) * 2008-02-26 2010-03-04 William Gerhart Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations
GB201113662D0 (en) * 2011-08-08 2011-09-21 Prosonix Ltd Pharmaceutical compositions
WO2013153349A2 (en) * 2012-04-11 2013-10-17 Cipla Limited Pharmaceutical composition
US20200405700A1 (en) * 2019-06-27 2020-12-31 Cai Gu Huang Inhalable formulation of a solution containing formoterol fumarate and aclidinium bromide

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
US5795564A (en) * 1991-04-05 1998-08-18 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
PT613371E (pt) * 1991-12-18 2002-07-31 Astrazeneca Ab Nova combinacao de formoterol e budesonido
DE69232034T2 (de) * 1991-12-18 2002-06-06 Minnesota Mining & Mfg Aerosolzusammensetzungen für Arzneimittelsuspensionen
ES2122261T3 (es) * 1993-03-17 1998-12-16 Minnesota Mining & Mfg Formulacion de aerosol que contiene un adyuvante de dispersion derivado de un ester, una amida o un mercaptoester.
GB9612297D0 (en) * 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
GB9616237D0 (en) * 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations

Also Published As

Publication number Publication date
AU764126B2 (en) 2003-08-14
US6150418A (en) 2000-11-21
UA71585C2 (uk) 2004-12-15
PE20001226A1 (es) 2000-11-01
TW562676B (en) 2003-11-21
DE19847969A1 (de) 2000-04-20
AR020830A1 (es) 2002-05-29
MY124329A (en) 2006-06-30
ATE218331T1 (de) 2002-06-15
ZA200103056B (en) 2002-01-23
RS49907B (sr) 2008-09-29
EG23820A (en) 2007-09-19
SA99200700B1 (ar) 2006-06-10
AU6201999A (en) 2000-05-08
YU26701A (sh) 2005-07-19
CO5261514A1 (es) 2003-03-31

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