CZ302292B6 - Linezolid-krystalická forma (Forma II) - Google Patents

Linezolid-krystalická forma (Forma II) Download PDF

Info

Publication number
CZ302292B6
CZ302292B6 CZ20022635A CZ20022635A CZ302292B6 CZ 302292 B6 CZ302292 B6 CZ 302292B6 CZ 20022635 A CZ20022635 A CZ 20022635A CZ 20022635 A CZ20022635 A CZ 20022635A CZ 302292 B6 CZ302292 B6 CZ 302292B6
Authority
CZ
Czechia
Prior art keywords
solvent
alkyl
methyl
phenyl
linezolid
Prior art date
Application number
CZ20022635A
Other languages
Czech (cs)
English (en)
Other versions
CZ20022635A3 (cs
Inventor
S. Bergren@Michael
Original Assignee
Pharmacia & Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22658183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CZ302292(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company
Publication of CZ20022635A3 publication Critical patent/CZ20022635A3/cs
Publication of CZ302292B6 publication Critical patent/CZ302292B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CZ20022635A 2000-02-02 2001-01-29 Linezolid-krystalická forma (Forma II) CZ302292B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17983700P 2000-02-02 2000-02-02

Publications (2)

Publication Number Publication Date
CZ20022635A3 CZ20022635A3 (cs) 2002-10-16
CZ302292B6 true CZ302292B6 (cs) 2011-02-09

Family

ID=22658183

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20022635A CZ302292B6 (cs) 2000-02-02 2001-01-29 Linezolid-krystalická forma (Forma II)

Country Status (30)

Country Link
EP (1) EP1255754B1 (cg-RX-API-DMAC7.html)
JP (1) JP5235256B2 (cg-RX-API-DMAC7.html)
KR (3) KR100864745B1 (cg-RX-API-DMAC7.html)
CN (1) CN1221547C (cg-RX-API-DMAC7.html)
AR (1) AR027261A1 (cg-RX-API-DMAC7.html)
AT (1) ATE297920T1 (cg-RX-API-DMAC7.html)
AU (1) AU782138B2 (cg-RX-API-DMAC7.html)
BR (1) BR0107667A (cg-RX-API-DMAC7.html)
CA (1) CA2395603C (cg-RX-API-DMAC7.html)
CO (1) CO5261555A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ302292B6 (cg-RX-API-DMAC7.html)
DE (1) DE60111497T2 (cg-RX-API-DMAC7.html)
DK (1) DK1255754T3 (cg-RX-API-DMAC7.html)
EA (1) EA004434B1 (cg-RX-API-DMAC7.html)
EE (1) EE05197B1 (cg-RX-API-DMAC7.html)
ES (1) ES2242728T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0301076A3 (cg-RX-API-DMAC7.html)
IL (1) IL151010A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA02007471A (cg-RX-API-DMAC7.html)
MY (1) MY122829A (cg-RX-API-DMAC7.html)
NO (2) NO323459B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ520541A (cg-RX-API-DMAC7.html)
PE (1) PE20011086A1 (cg-RX-API-DMAC7.html)
PL (1) PL356433A1 (cg-RX-API-DMAC7.html)
PT (1) PT1255754E (cg-RX-API-DMAC7.html)
SI (1) SI1255754T1 (cg-RX-API-DMAC7.html)
SK (1) SK287025B6 (cg-RX-API-DMAC7.html)
TW (1) TWI297687B (cg-RX-API-DMAC7.html)
WO (1) WO2001057035A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200205162B (cg-RX-API-DMAC7.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100490643B1 (ko) * 2002-10-29 2005-05-19 한국과학기술연구원 새로운 메틸리덴 피페리딘일 옥사졸리딘온 유도체 및이들의 제조방법
ES2803516T3 (es) 2003-10-16 2021-01-27 Symed Labs Ltd Una forma cristalina de linezolid
ES2294494T3 (es) 2004-04-19 2008-04-01 Symed Labs Limited Un nuevo procedimiento para la preparacion de linezolid y compuestos relacionados.
WO2006110155A1 (en) * 2004-06-29 2006-10-19 Teva Pharmaceutical Industries Ltd Solid forms of linezolid and processes for preparation thereof
CA2572054A1 (en) * 2004-06-29 2006-01-12 Teva Pharmaceutical Industries Ltd. Crystalline form iv of linezolid
CA2602073A1 (en) * 2005-02-24 2006-08-31 Teva Pharmaceutical Industries Ltd. Processes for the preparation of linezolid intermediate
JP2008514734A (ja) * 2005-06-22 2008-05-08 テバ ファーマシューティカル インダストリーズ リミティド マレイン酸テガセロドの多型体
PL1749517T3 (pl) * 2005-07-20 2008-12-31 Teva Pharma Trwała farmaceutyczna kompozycja zawierająca linezolid
WO2007102082A1 (en) * 2006-03-09 2007-09-13 Glenmark Pharmaceuticals Limited High oxazolidinone content solid dosage forms
US20080139563A1 (en) * 2006-10-23 2008-06-12 Concert Pharmaceuticals Inc. Oxazolidinone derivatives and methods of use
WO2011050826A1 (en) 2009-10-28 2011-05-05 Synthon B.V. Process for making crystalline form a of linezolid
JP5865898B2 (ja) 2010-04-30 2016-02-17 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ リネゾリドを調製するためのプロセス
EP2690100A1 (en) 2010-08-11 2014-01-29 Synhton B.V. Process for making linezolid
EP2603505A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
CN103402990A (zh) * 2011-02-24 2013-11-20 李药业有限公司 无水利奈唑胺晶型-ii
WO2012119653A1 (en) 2011-03-09 2012-09-13 Synthon Bv Process for making crystalline form a of linezolid
CN102731341A (zh) * 2011-04-13 2012-10-17 上海医药工业研究院 用于制备利奈唑胺的中间体及其制备方法
CN102766106A (zh) * 2011-05-03 2012-11-07 江苏豪森医药集团有限公司 利奈唑胺的新晶型及其制备方法
CN102399200B (zh) * 2011-12-14 2013-12-04 浙江新东港药业股份有限公司 一种利用悬浮结晶法制备利奈唑胺晶型ⅰ的方法
IN2014DN06213A (cg-RX-API-DMAC7.html) 2012-01-24 2015-10-23 Jubilant Life Sciences Ltd
WO2013120496A1 (en) 2012-02-14 2013-08-22 Pharmathen S.A. Process for the preparation of linezolid in crystalline form and salts thereof
CN102643245A (zh) * 2012-04-10 2012-08-22 杭州华东医药集团生物工程研究所有限公司 一种利奈唑胺晶型及其制备方法
WO2014071990A1 (en) 2012-11-09 2014-05-15 Synthon Bv Process for making linezolid
KR102615354B1 (ko) 2016-11-16 2023-12-21 페르시카 파마슈티컬스 리미티드 요통을 위한 항생제 제형
RU2771279C2 (ru) 2017-11-16 2022-04-29 Персика Фармасьютикалз Лтд. Композиции линезолида

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
US5837870A (en) * 1996-04-11 1998-11-17 Pharmacia & Upjohn Company Process to prepare oxazolidinones
WO1999024393A1 (en) * 1997-11-07 1999-05-20 Pharmacia & Upjohn Company Process to produce oxazolidinones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
US5837870A (en) * 1996-04-11 1998-11-17 Pharmacia & Upjohn Company Process to prepare oxazolidinones
WO1999024393A1 (en) * 1997-11-07 1999-05-20 Pharmacia & Upjohn Company Process to produce oxazolidinones

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Brickner S.J., et al.: Journal of Medicinal Chemistry 1996, 39 (3), str. 673-679 *

Also Published As

Publication number Publication date
AU3275501A (en) 2001-08-14
CZ20022635A3 (cs) 2002-10-16
PT1255754E (pt) 2005-11-30
DE60111497D1 (de) 2005-07-21
KR20070087178A (ko) 2007-08-27
NO20023654D0 (no) 2002-08-01
EA200200819A1 (ru) 2003-02-27
CA2395603A1 (en) 2001-08-09
EE05197B1 (et) 2009-08-17
ES2242728T3 (es) 2005-11-16
ATE297920T1 (de) 2005-07-15
PL356433A1 (en) 2004-06-28
EP1255754A1 (en) 2002-11-13
SK287025B6 (sk) 2009-10-07
KR100781815B1 (ko) 2007-12-03
AR027261A1 (es) 2003-03-19
KR20080044358A (ko) 2008-05-20
NO20065836L (no) 2002-08-01
CN1394207A (zh) 2003-01-29
SK9942002A3 (en) 2002-11-06
IL151010A0 (en) 2003-02-12
CA2395603C (en) 2010-03-23
NO20023654L (no) 2002-08-01
CN1221547C (zh) 2005-10-05
HK1051196A1 (en) 2003-07-25
AU782138B2 (en) 2005-07-07
TWI297687B (en) 2008-06-11
KR100864745B1 (ko) 2008-10-22
SI1255754T1 (sl) 2005-12-31
EE200200420A (et) 2003-12-15
KR20020072300A (ko) 2002-09-14
EP1255754B1 (en) 2005-06-15
ZA200205162B (en) 2003-09-29
MXPA02007471A (es) 2002-12-13
EA004434B1 (ru) 2004-04-29
CO5261555A1 (es) 2003-03-31
MY122829A (en) 2006-05-31
DE60111497T2 (de) 2006-05-18
NO323459B1 (no) 2007-05-14
NZ520541A (en) 2004-02-27
HUP0301076A3 (en) 2004-06-28
BR0107667A (pt) 2002-10-08
PE20011086A1 (es) 2001-10-04
JP5235256B2 (ja) 2013-07-10
HUP0301076A2 (hu) 2003-08-28
DK1255754T3 (da) 2005-08-22
WO2001057035A1 (en) 2001-08-09
JP2003522175A (ja) 2003-07-22

Similar Documents

Publication Publication Date Title
CZ302292B6 (cs) Linezolid-krystalická forma (Forma II)
US6444813B2 (en) Linezolid-crystal form II
EP0579681A1 (en) Crystalline tiagabine hydrochloride monohydrate, its preparation and use
WO2011051384A1 (en) Process for making crystalline form a of linezolid
KR20090082399A (ko) 벤조티오펜 화합물의 결정형 및 그의 제조방법
EP2621889B1 (en) Process for making fingolimod hydrochloride crystals
US20040063782A1 (en) Bicalutamide forms
WO2012019632A1 (en) Process for making linezolid
JP7704835B2 (ja) ビランテロールトリフェナテートの精製方法
HK1051196B (en) Linezolid-crystal form ii
EP1981501A2 (en) Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine
WO2009032294A2 (en) Processes for the preparation of a linezolid intermediate, linezolid hydroxide
US20110184067A1 (en) O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
EP1785411A1 (en) Protriptyline hydrochloride crystalline form
FR2528832A1 (fr) Nouveaux derives du benzene, leur preparation et leur utilisation comme medicaments
EP2493867A1 (en) Process for making crystalline form a of linezolid
HUP0900062A2 (en) Novel polymorphs and amorph forms of desvenlafaxine fumarate

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of fee

Effective date: 20110503