CZ299638B6 - Lécivo pro genovou terapii, které se vnáší do nádoru za aplikace slabého elektrického pole, a kombinovaný produkt pro genovou terapii - Google Patents

Lécivo pro genovou terapii, které se vnáší do nádoru za aplikace slabého elektrického pole, a kombinovaný produkt pro genovou terapii Download PDF

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Publication number
CZ299638B6
CZ299638B6 CZ0475499A CZ475499A CZ299638B6 CZ 299638 B6 CZ299638 B6 CZ 299638B6 CZ 0475499 A CZ0475499 A CZ 0475499A CZ 475499 A CZ475499 A CZ 475499A CZ 299638 B6 CZ299638 B6 CZ 299638B6
Authority
CZ
Czechia
Prior art keywords
nucleic acid
combination product
pulses
use according
electric field
Prior art date
Application number
CZ0475499A
Other languages
Czech (cs)
English (en)
Other versions
CZ475499A3 (cs
Inventor
Bureau@Michel
Mir@Lluis
Scherman@Daniel
Original Assignee
Rhone-Poulenc Rorer S. A.
Institut Gustave Roussy
Centre National De La Recherche Scientifique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9708232A external-priority patent/FR2765241B1/fr
Application filed by Rhone-Poulenc Rorer S. A., Institut Gustave Roussy, Centre National De La Recherche Scientifique filed Critical Rhone-Poulenc Rorer S. A.
Publication of CZ475499A3 publication Critical patent/CZ475499A3/cs
Publication of CZ299638B6 publication Critical patent/CZ299638B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
CZ0475499A 1997-06-30 1998-06-30 Lécivo pro genovou terapii, které se vnáší do nádoru za aplikace slabého elektrického pole, a kombinovaný produkt pro genovou terapii CZ299638B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9708232A FR2765241B1 (fr) 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans les cellules d'organismes eucaryotes pluricellulaires et combinaison permettant la mise en oeuvre du procede
US6748797P 1997-12-01 1997-12-01

Publications (2)

Publication Number Publication Date
CZ475499A3 CZ475499A3 (cs) 2000-07-12
CZ299638B6 true CZ299638B6 (cs) 2008-10-01

Family

ID=26233647

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ0475499A CZ299638B6 (cs) 1997-06-30 1998-06-30 Lécivo pro genovou terapii, které se vnáší do nádoru za aplikace slabého elektrického pole, a kombinovaný produkt pro genovou terapii

Country Status (16)

Country Link
US (1) US6528315B2 (zh)
EP (1) EP0991425B1 (zh)
JP (1) JP4664450B2 (zh)
KR (1) KR20010020570A (zh)
CN (1) CN1261808A (zh)
AT (1) ATE290403T1 (zh)
AU (1) AU8444698A (zh)
BR (1) BR9810372A (zh)
CA (1) CA2294802A1 (zh)
CZ (1) CZ299638B6 (zh)
DE (1) DE69829287T2 (zh)
HU (1) HUP0004728A3 (zh)
IL (1) IL133708A0 (zh)
NO (1) NO327499B1 (zh)
PL (1) PL337584A1 (zh)
WO (1) WO1999001157A1 (zh)

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Also Published As

Publication number Publication date
CZ475499A3 (cs) 2000-07-12
HUP0004728A1 (hu) 2001-04-28
ATE290403T1 (de) 2005-03-15
KR20010020570A (ko) 2001-03-15
NO996541D0 (no) 1999-12-29
BR9810372A (pt) 2000-09-05
JP4664450B2 (ja) 2011-04-06
PL337584A1 (en) 2000-08-28
JP2002507984A (ja) 2002-03-12
US6528315B2 (en) 2003-03-04
NO327499B1 (no) 2009-07-20
DE69829287D1 (de) 2005-04-14
IL133708A0 (en) 2001-04-30
CN1261808A (zh) 2000-08-02
NO996541L (no) 2000-02-17
HUP0004728A3 (en) 2003-08-28
WO1999001157A1 (fr) 1999-01-14
AU8444698A (en) 1999-01-25
DE69829287T2 (de) 2006-04-13
EP0991425A1 (fr) 2000-04-12
EP0991425B1 (fr) 2005-03-09
US20020012914A1 (en) 2002-01-31
CA2294802A1 (fr) 1999-01-14

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PD00 Pending as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20180630