CZ296577B6 - Polymer a jeho pouzití ke stimulaci imunitní odpovedi - Google Patents

Polymer a jeho pouzití ke stimulaci imunitní odpovedi Download PDF

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Publication number
CZ296577B6
CZ296577B6 CZ0073796A CZ73796A CZ296577B6 CZ 296577 B6 CZ296577 B6 CZ 296577B6 CZ 0073796 A CZ0073796 A CZ 0073796A CZ 73796 A CZ73796 A CZ 73796A CZ 296577 B6 CZ296577 B6 CZ 296577B6
Authority
CZ
Czechia
Prior art keywords
polymer
synpol
hyaluronidase
present
ethylenepiperazine
Prior art date
Application number
CZ0073796A
Other languages
Czech (cs)
English (en)
Other versions
CZ73796A3 (en
Inventor
V. Petrov@Rem
M. Khaitov@Rakhim
I. Ataullakhanov@Ravshan
V. Nekrasov@Arkady
K. Daugalieva@Emma
Original Assignee
Petrovax, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/120,001 external-priority patent/US5503830A/en
Application filed by Petrovax, Inc. filed Critical Petrovax, Inc.
Publication of CZ73796A3 publication Critical patent/CZ73796A3/cs
Publication of CZ296577B6 publication Critical patent/CZ296577B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0622—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0633—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only two nitrogen atoms in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/091—Phenol resins; Amino resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyethers (AREA)
  • Enzymes And Modification Thereof (AREA)
CZ0073796A 1993-09-10 1994-09-12 Polymer a jeho pouzití ke stimulaci imunitní odpovedi CZ296577B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/120,001 US5503830A (en) 1993-09-10 1993-09-10 Compounds having immunostimulating activity and methods of use thereof
US20748694A 1994-03-07 1994-03-07

Publications (2)

Publication Number Publication Date
CZ73796A3 CZ73796A3 (en) 1996-08-14
CZ296577B6 true CZ296577B6 (cs) 2006-04-12

Family

ID=26817942

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ0073796A CZ296577B6 (cs) 1993-09-10 1994-09-12 Polymer a jeho pouzití ke stimulaci imunitní odpovedi

Country Status (19)

Country Link
US (1) US5811100A (el)
EP (2) EP1108738B1 (el)
JP (1) JP3138476B2 (el)
KR (2) KR100270980B1 (el)
CN (1) CN1116076C (el)
AT (2) ATE202710T1 (el)
AU (1) AU696748B2 (el)
BR (1) BR9407533A (el)
CA (1) CA2171462C (el)
CZ (1) CZ296577B6 (el)
DE (2) DE69427653T2 (el)
DK (2) DK1108738T3 (el)
ES (2) ES2194666T3 (el)
GR (1) GR3036780T3 (el)
HU (1) HU222189B1 (el)
NZ (1) NZ274343A (el)
PT (2) PT1108738E (el)
SI (1) SI1108738T1 (el)
WO (1) WO1995007100A1 (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1581400A (en) * 1999-12-22 2001-07-03 Om Pharma Acyl pseudopeptides bearing a functionalised auxiliary spacer
KR101162241B1 (ko) * 2009-12-30 2012-07-04 박정자 양식어류 기생충 구충용 조성물
RU2616528C1 (ru) 2015-12-04 2017-04-17 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НПО Петровакс Фарм" Способ получения конъюгата гиалуронидазы с производными полиэтиленпиперазина и применение полученного конъюгата
RU2737271C2 (ru) * 2018-06-27 2020-11-26 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НПО Петровакс Фарм" Сополимеры ди-N-оксидов поли-1,4-этиленпиперазина и способы их получения
WO2022081040A1 (ru) * 2020-10-14 2022-04-21 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НПО Петровакс Фарм" Способ синтеза поли-1,4-этиленпиперазина, сополимера n-оксида-1,4-этиленпиперазина, (n-карбоксиметил)-1,4-этиленпиперазиний бромида и их производных

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390148A (en) * 1965-07-28 1968-06-25 Pfizer & Co C Novel thiazine and thiazoline anthelmintic agents
US3579510A (en) * 1967-08-30 1971-05-18 Pfizer 3-(hydroxy-phenyl) substituted amidines and derivatives thereof as anthelmintic agents
US3896227A (en) * 1971-08-04 1975-07-22 Pfizer 1-(3-hydroxystyryl pyridinium salts and their derivatives as whipworm control agents
US5503830A (en) * 1993-09-10 1996-04-02 Petrovax, L.L.C. Compounds having immunostimulating activity and methods of use thereof

Also Published As

Publication number Publication date
SI1108738T1 (en) 2003-08-31
KR100270980B1 (ko) 2000-11-01
AU7834794A (en) 1995-03-27
AU696748B2 (en) 1998-09-17
CA2171462C (en) 2003-12-09
EP0789586A1 (en) 1997-08-20
WO1995007100A1 (en) 1995-03-16
CZ73796A3 (en) 1996-08-14
HU222189B1 (hu) 2003-05-28
ATE236948T1 (de) 2003-04-15
JPH09502444A (ja) 1997-03-11
DE69432493T2 (de) 2003-10-30
GR3036780T3 (en) 2002-01-31
ES2160129T3 (es) 2001-11-01
DE69427653T2 (de) 2002-05-08
DE69432493D1 (de) 2003-05-15
CN1130876A (zh) 1996-09-11
EP1108738A2 (en) 2001-06-20
CN1116076C (zh) 2003-07-30
JP3138476B2 (ja) 2001-02-26
NZ274343A (en) 2004-12-24
PT1108738E (pt) 2003-07-31
ATE202710T1 (de) 2001-07-15
US5811100A (en) 1998-09-22
EP1108738A3 (en) 2001-07-25
BR9407533A (pt) 1997-08-26
HUT74663A (en) 1997-01-28
DK1108738T3 (da) 2003-07-28
EP0789586B1 (en) 2001-07-04
HU9600591D0 (en) 1996-05-28
ES2194666T3 (es) 2003-12-01
KR100296970B1 (ko) 2001-09-22
CA2171462A1 (en) 1995-03-16
EP0789586A4 (en) 1999-05-26
EP1108738B1 (en) 2003-04-09
PT789586E (pt) 2001-12-28
DE69427653D1 (de) 2001-08-09
DK0789586T3 (da) 2001-10-15

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20080912