ES2160129T3 - Compuestos para la prevencion y tratamiento de infecciones por helmintos. - Google Patents
Compuestos para la prevencion y tratamiento de infecciones por helmintos.Info
- Publication number
- ES2160129T3 ES2160129T3 ES94929200T ES94929200T ES2160129T3 ES 2160129 T3 ES2160129 T3 ES 2160129T3 ES 94929200 T ES94929200 T ES 94929200T ES 94929200 T ES94929200 T ES 94929200T ES 2160129 T3 ES2160129 T3 ES 2160129T3
- Authority
- ES
- Spain
- Prior art keywords
- helmintos
- infections
- prevention
- compounds
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
- C08G73/0622—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
- C08G73/0633—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only two nitrogen atoms in the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0003—Invertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/091—Phenol resins; Amino resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyethers (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
COMPUESTO PARA PROTEGER A UN VERTEBRADO CONTRA LA INFECCION POR HELMINTIDOS QUE INCLUYE HIALURONIDASA ACOPLADA DE FORMA COVALENTE A UN VEHICULO INMUNOESTUMLADOR, EN LA FORMA PREFERIDA, EL VEHICULO DE INMUNOESTIMULACION AL QUE SE ACOPLA COVALENTEMENTE LA HIALURONIDASA TIENE UN COPOLIMERO DE BROMURO DE ETILENEPIPERAZINA N-OXIDO Y N-ETILACETILETILENOPIPERAZINO ( EN LO SUCESIVO LLAMADO "SYNPOL"), Y UN PROCESO PARA PROTEGER AL VERTEBRADO CONTRA LA INFECCION POR HELMINTIDOS QUE SUPONE LA ADMINISTRACION AL VERTEBRADO DE UNA CANTIDAD EFECTIVA TERAPEUTICAMENTE DE UN COMPUESTO QUE INCLUYE HIALURONIDASA ACOPLADA DE FORMA COVALENTE A UN VEHICULO INMUNOESTIMULANTE, PREFERIBLEMENTE SYNPOL, EN LA FORMA PREFERIDA, SIENDO ADMINISTRANDO EL COMPUESTO AL VERTEBRADO EN FORMA DE UNA VACUNA QUE INCLUYE, DE FORMA MEZCLADA CON EL COMPUESTO, SYNPOL, Y UN PROCESO QUE SUPONE LA REACCION DE HIALURONIDASA Y UN VEHICULO INMUNOESTIMULANTE BAJO CONDICIONES DE TIEMPO Y TEMPERATURA QUE SE PUEDAN ACOPLAR COVALENTEMENTE LA HIALURONIDASA Y DICHO VEHICULO INMUNOGENICO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/120,001 US5503830A (en) | 1993-09-10 | 1993-09-10 | Compounds having immunostimulating activity and methods of use thereof |
US20748694A | 1994-03-07 | 1994-03-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2160129T3 true ES2160129T3 (es) | 2001-11-01 |
Family
ID=26817942
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES00125257T Expired - Lifetime ES2194666T3 (es) | 1993-09-10 | 1994-09-12 | Portador inmunoestimulante para vacunas. |
ES94929200T Expired - Lifetime ES2160129T3 (es) | 1993-09-10 | 1994-09-12 | Compuestos para la prevencion y tratamiento de infecciones por helmintos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES00125257T Expired - Lifetime ES2194666T3 (es) | 1993-09-10 | 1994-09-12 | Portador inmunoestimulante para vacunas. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5811100A (es) |
EP (2) | EP1108738B1 (es) |
JP (1) | JP3138476B2 (es) |
KR (2) | KR100270980B1 (es) |
CN (1) | CN1116076C (es) |
AT (2) | ATE202710T1 (es) |
AU (1) | AU696748B2 (es) |
BR (1) | BR9407533A (es) |
CA (1) | CA2171462C (es) |
CZ (1) | CZ296577B6 (es) |
DE (2) | DE69427653T2 (es) |
DK (2) | DK1108738T3 (es) |
ES (2) | ES2194666T3 (es) |
GR (1) | GR3036780T3 (es) |
HU (1) | HU222189B1 (es) |
NZ (1) | NZ274343A (es) |
PT (2) | PT1108738E (es) |
SI (1) | SI1108738T1 (es) |
WO (1) | WO1995007100A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1581400A (en) * | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
KR101162241B1 (ko) * | 2009-12-30 | 2012-07-04 | 박정자 | 양식어류 기생충 구충용 조성물 |
RU2616528C1 (ru) | 2015-12-04 | 2017-04-17 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НПО Петровакс Фарм" | Способ получения конъюгата гиалуронидазы с производными полиэтиленпиперазина и применение полученного конъюгата |
RU2737271C2 (ru) * | 2018-06-27 | 2020-11-26 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НПО Петровакс Фарм" | Сополимеры ди-N-оксидов поли-1,4-этиленпиперазина и способы их получения |
WO2022081040A1 (ru) * | 2020-10-14 | 2022-04-21 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НПО Петровакс Фарм" | Способ синтеза поли-1,4-этиленпиперазина, сополимера n-оксида-1,4-этиленпиперазина, (n-карбоксиметил)-1,4-этиленпиперазиний бромида и их производных |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3390148A (en) * | 1965-07-28 | 1968-06-25 | Pfizer & Co C | Novel thiazine and thiazoline anthelmintic agents |
US3579510A (en) * | 1967-08-30 | 1971-05-18 | Pfizer | 3-(hydroxy-phenyl) substituted amidines and derivatives thereof as anthelmintic agents |
US3896227A (en) * | 1971-08-04 | 1975-07-22 | Pfizer | 1-(3-hydroxystyryl pyridinium salts and their derivatives as whipworm control agents |
US5503830A (en) * | 1993-09-10 | 1996-04-02 | Petrovax, L.L.C. | Compounds having immunostimulating activity and methods of use thereof |
-
1994
- 1994-09-12 ES ES00125257T patent/ES2194666T3/es not_active Expired - Lifetime
- 1994-09-12 CN CN94193357A patent/CN1116076C/zh not_active Expired - Fee Related
- 1994-09-12 CA CA002171462A patent/CA2171462C/en not_active Expired - Fee Related
- 1994-09-12 KR KR1019960701239A patent/KR100270980B1/ko not_active IP Right Cessation
- 1994-09-12 PT PT00125257T patent/PT1108738E/pt unknown
- 1994-09-12 DE DE69427653T patent/DE69427653T2/de not_active Expired - Lifetime
- 1994-09-12 DK DK00125257T patent/DK1108738T3/da active
- 1994-09-12 WO PCT/US1994/010346 patent/WO1995007100A1/en active IP Right Grant
- 1994-09-12 DE DE69432493T patent/DE69432493T2/de not_active Expired - Lifetime
- 1994-09-12 EP EP00125257A patent/EP1108738B1/en not_active Expired - Lifetime
- 1994-09-12 SI SI9430448T patent/SI1108738T1/xx unknown
- 1994-09-12 CZ CZ0073796A patent/CZ296577B6/cs not_active IP Right Cessation
- 1994-09-12 EP EP94929200A patent/EP0789586B1/en not_active Expired - Lifetime
- 1994-09-12 ES ES94929200T patent/ES2160129T3/es not_active Expired - Lifetime
- 1994-09-12 HU HU9600591A patent/HU222189B1/hu active IP Right Grant
- 1994-09-12 BR BR9407533A patent/BR9407533A/pt not_active Application Discontinuation
- 1994-09-12 AT AT94929200T patent/ATE202710T1/de active
- 1994-09-12 PT PT94929200T patent/PT789586E/pt unknown
- 1994-09-12 JP JP07508836A patent/JP3138476B2/ja not_active Expired - Fee Related
- 1994-09-12 AU AU78347/94A patent/AU696748B2/en not_active Ceased
- 1994-09-12 NZ NZ27434394A patent/NZ274343A/xx not_active IP Right Cessation
- 1994-09-12 DK DK94929200T patent/DK0789586T3/da active
- 1994-09-12 AT AT00125257T patent/ATE236948T1/de active
-
1996
- 1996-05-15 US US08/655,282 patent/US5811100A/en not_active Expired - Lifetime
-
2000
- 2000-06-13 KR KR1020000032523A patent/KR100296970B1/ko not_active IP Right Cessation
-
2001
- 2001-10-03 GR GR20010401641T patent/GR3036780T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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