CZ289857B6 - Kosmetický prostředek - Google Patents
Kosmetický prostředek Download PDFInfo
- Publication number
- CZ289857B6 CZ289857B6 CZ19991087A CZ108799A CZ289857B6 CZ 289857 B6 CZ289857 B6 CZ 289857B6 CZ 19991087 A CZ19991087 A CZ 19991087A CZ 108799 A CZ108799 A CZ 108799A CZ 289857 B6 CZ289857 B6 CZ 289857B6
- Authority
- CZ
- Czechia
- Prior art keywords
- retinol
- cosmetic composition
- retinyl
- carbon atoms
- composition according
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 61
- 239000002537 cosmetic Substances 0.000 title claims abstract description 38
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 93
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 54
- 235000020944 retinol Nutrition 0.000 claims abstract description 50
- 229960003471 retinol Drugs 0.000 claims abstract description 48
- 239000011607 retinol Substances 0.000 claims abstract description 48
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 27
- 239000000194 fatty acid Substances 0.000 claims abstract description 27
- 229930195729 fatty acid Natural products 0.000 claims abstract description 27
- 150000004665 fatty acids Chemical class 0.000 claims abstract description 23
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 20
- WWDMJSSVVPXVSV-YCNIQYBTSA-N retinyl ester Chemical compound CC1CCCC(C)(C)C1\C=C\C(\C)=C\C=C\C(\C)=C\C(O)=O WWDMJSSVVPXVSV-YCNIQYBTSA-N 0.000 claims abstract description 15
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 14
- 229910019142 PO4 Inorganic materials 0.000 claims abstract description 6
- 125000003545 alkoxy group Chemical group 0.000 claims abstract description 6
- 239000010452 phosphate Substances 0.000 claims abstract description 6
- 125000003342 alkenyl group Chemical group 0.000 claims abstract description 3
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims description 15
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims description 15
- 229930002330 retinoic acid Natural products 0.000 claims description 15
- 229960001727 tretinoin Drugs 0.000 claims description 15
- 238000005886 esterification reaction Methods 0.000 claims description 12
- 102100033356 Lecithin retinol acyltransferase Human genes 0.000 claims description 10
- 230000032050 esterification Effects 0.000 claims description 10
- 108010084957 lecithin-retinol acyltransferase Proteins 0.000 claims description 10
- 210000001589 microsome Anatomy 0.000 claims description 8
- 229940108325 retinyl palmitate Drugs 0.000 claims description 8
- 239000011769 retinyl palmitate Substances 0.000 claims description 8
- 235000019172 retinyl palmitate Nutrition 0.000 claims description 8
- 230000000694 effects Effects 0.000 claims description 6
- 238000000338 in vitro Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 claims description 6
- CBKLICUQYUTWQL-XWGBWKJCSA-N methyl (3s,4r)-3-methyl-1-(2-phenylethyl)-4-(n-propanoylanilino)piperidine-4-carboxylate;oxalic acid Chemical compound OC(=O)C(O)=O.CCC(=O)N([C@]1([C@H](CN(CCC=2C=CC=CC=2)CC1)C)C(=O)OC)C1=CC=CC=C1 CBKLICUQYUTWQL-XWGBWKJCSA-N 0.000 claims description 3
- 229960000342 retinol acetate Drugs 0.000 claims description 3
- 239000011770 retinyl acetate Substances 0.000 claims description 3
- 235000019173 retinyl acetate Nutrition 0.000 claims description 3
- 229940049964 oleate Drugs 0.000 claims 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 1
- 230000037303 wrinkles Effects 0.000 abstract description 4
- 206010013786 Dry skin Diseases 0.000 abstract 1
- 230000037336 dry skin Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 31
- 150000001875 compounds Chemical class 0.000 description 21
- 210000003491 skin Anatomy 0.000 description 19
- -1 retinol ester Chemical class 0.000 description 18
- 125000000946 retinyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 description 18
- 210000002510 keratinocyte Anatomy 0.000 description 17
- 239000000463 material Substances 0.000 description 17
- 150000002148 esters Chemical class 0.000 description 13
- 108060008539 Transglutaminase Proteins 0.000 description 12
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 12
- 238000012360 testing method Methods 0.000 description 12
- 102000003601 transglutaminase Human genes 0.000 description 12
- 102000004190 Enzymes Human genes 0.000 description 11
- 108090000790 Enzymes Proteins 0.000 description 11
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- 238000006243 chemical reaction Methods 0.000 description 10
- 230000005764 inhibitory process Effects 0.000 description 10
- 239000002609 medium Substances 0.000 description 10
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- 230000004069 differentiation Effects 0.000 description 8
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- 239000011534 wash buffer Substances 0.000 description 8
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- 102100027841 Acyl-CoA wax alcohol acyltransferase 2 Human genes 0.000 description 6
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- DOEADYYICZVJDD-UHFFFAOYSA-N [4-[(4-aminophenyl)diazenyl]phenyl]arsonic acid Chemical compound C1=CC(N)=CC=C1N=NC1=CC=C([As](O)(O)=O)C=C1 DOEADYYICZVJDD-UHFFFAOYSA-N 0.000 description 6
- 108010024239 aromatic amino acid aminotransferase Proteins 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- 150000004347 all-trans-retinol derivatives Chemical class 0.000 description 5
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- 239000004014 plasticizer Substances 0.000 description 5
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- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 4
- XWCYDHJOKKGVHC-UHFFFAOYSA-N Vitamin A2 Chemical compound OCC=C(C)C=CC=C(C)C=CC1=C(C)C=CCC1(C)C XWCYDHJOKKGVHC-UHFFFAOYSA-N 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 150000001298 alcohols Chemical group 0.000 description 3
- 239000011717 all-trans-retinol Substances 0.000 description 3
- 229940098773 bovine serum albumin Drugs 0.000 description 3
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- 210000002615 epidermis Anatomy 0.000 description 3
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- 229930195733 hydrocarbon Chemical group 0.000 description 3
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- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 229960001679 octinoxate Drugs 0.000 description 3
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 description 3
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
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- 108010058734 transglutaminase 1 Proteins 0.000 description 3
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- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-HWCYFHEPSA-N 13-cis-retinol Chemical compound OC/C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-HWCYFHEPSA-N 0.000 description 2
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- FPIPGXGPPPQFEQ-MKOSUFFBSA-N 9-cis-retinol Chemical compound OC\C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-MKOSUFFBSA-N 0.000 description 2
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- 239000004322 Butylated hydroxytoluene Substances 0.000 description 2
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/722,539 US5955092A (en) | 1996-09-27 | 1996-09-27 | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
| PCT/EP1997/005138 WO1998013018A1 (en) | 1996-09-27 | 1997-09-18 | Skin care composition containing an amide and retinol or retinyl ester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CZ108799A3 CZ108799A3 (cs) | 1999-08-11 |
| CZ289857B6 true CZ289857B6 (cs) | 2002-04-17 |
Family
ID=24902281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ19991087A CZ289857B6 (cs) | 1996-09-27 | 1997-09-18 | Kosmetický prostředek |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5955092A (OSRAM) |
| EP (1) | EP0929288B1 (OSRAM) |
| JP (1) | JP3667772B2 (OSRAM) |
| KR (1) | KR100320137B1 (OSRAM) |
| CN (1) | CN1093757C (OSRAM) |
| AR (1) | AR009099A1 (OSRAM) |
| AU (1) | AU714982B2 (OSRAM) |
| BR (1) | BR9711421B1 (OSRAM) |
| CA (1) | CA2266925C (OSRAM) |
| CZ (1) | CZ289857B6 (OSRAM) |
| DE (1) | DE69718023T2 (OSRAM) |
| ES (1) | ES2188903T3 (OSRAM) |
| ID (1) | ID21922A (OSRAM) |
| IN (1) | IN189577B (OSRAM) |
| PL (1) | PL188577B1 (OSRAM) |
| RU (1) | RU2177780C2 (OSRAM) |
| TW (1) | TW491706B (OSRAM) |
| WO (1) | WO1998013018A1 (OSRAM) |
| ZA (1) | ZA978653B (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ300666B6 (cs) * | 1998-02-26 | 2009-07-15 | Unilever N. V. | Kosmetický prostredek k péci o pokožku |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6210693B1 (en) * | 1998-02-10 | 2001-04-03 | Shiseido Company, Ltd. | Oil-in-water type emulsified composition |
| GB9918022D0 (en) * | 1999-07-30 | 1999-09-29 | Unilever Plc | Skin care composition |
| GB9918025D0 (en) * | 1999-07-30 | 1999-09-29 | Unilever Plc | Skin care composition |
| AU1701501A (en) * | 1999-12-14 | 2001-06-25 | Unilever Plc | Cosmetic skin conditioning compositions containing red yeast rice extract |
| US20040043044A1 (en) | 2000-06-30 | 2004-03-04 | Granger Stewart Paton | Skin conditioning compositions containing compounds for mimicking the effect on skin of retinoic acid |
| US6372795B1 (en) * | 2000-06-30 | 2002-04-16 | Unilever Home And Personal Care Usa, A Division Of Conopco, Inc. | Cosmetic compositions containing substituted amide derivatives |
| WO2002053125A2 (en) * | 2000-12-28 | 2002-07-11 | Unilever Plc | Skin care product containing a retinoid and a retinoid booster system in a dual compartment package |
| US6949247B2 (en) | 2000-12-28 | 2005-09-27 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Stable skin care compositions containing a retinoid and a retinoid booster system |
| FR2834216B1 (fr) * | 2001-12-27 | 2004-04-30 | Pharmascience Lab | Composition cosmetique ou pharmaceutique comprenant au moins une oxazoline pour inhiber la migration des cellules de langerhans, et ses utilisations |
| US8221728B2 (en) * | 2004-02-24 | 2012-07-17 | L'oreal | Silanic para-aminobenzalmalonate-substituted s-triazine compounds and photoprotective compositions comprised thereof |
| JP5140824B2 (ja) * | 2006-04-19 | 2013-02-13 | 国立大学法人 東京大学 | リゾホスファチジルスレオニンおよびその誘導体 |
| RU2501544C2 (ru) * | 2008-12-22 | 2013-12-20 | Джонсон Энд Джонсон Конзьюмер Холдингз Франс | Композиция и способ лечения патологических состояний кожи |
| US10660866B2 (en) * | 2018-09-10 | 2020-05-26 | Johnson & Johnson Consumer Inc. | Retinol oil composition |
| CN115551461A (zh) | 2020-05-09 | 2022-12-30 | 联合利华知识产权控股有限公司 | 包含视觉上不同的水相和油相的个人护理组合物 |
| US12478564B2 (en) | 2020-05-09 | 2025-11-25 | Conopco, Inc. | Personal care composition with visually distinct aqueous and oil phase |
| EP4146140A1 (en) * | 2020-05-09 | 2023-03-15 | Unilever IP Holdings B.V. | Personal care composition with visually distinct aqueous and oil phase |
| MX2022014729A (es) | 2020-05-29 | 2023-01-04 | Unilever Ip Holdings B V | Composicion cosmetica con estabilidad de color mejorada para precursor del acido retinoico. |
| US20240252406A1 (en) | 2021-06-24 | 2024-08-01 | Conopco, Inc., D/B/A Unilever | Cosmetic composition with enhanced color stability |
| EP4637690A1 (en) | 2022-12-21 | 2025-10-29 | Unilever IP Holdings B.V. | Oil-continuous cosmetic composition |
| WO2025140995A1 (en) | 2023-12-29 | 2025-07-03 | Unilever Ip Holdings B.V. | Cosmetic composition with enhanced color stability |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1126289A (en) * | 1966-05-12 | 1968-09-05 | Hoffmann La Roche | Water-dispersible water-free vitamin preparations and a process for the manufacture thereof |
| US3883661A (en) * | 1971-11-09 | 1975-05-13 | Syntex Inc | Acne treatment |
| US4363815A (en) * | 1975-07-23 | 1982-12-14 | Yu Ruey J | Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions |
| US4380549A (en) * | 1975-07-23 | 1983-04-19 | Scott Eugene J Van | Topical treatment of dry skin |
| DE2631284A1 (de) * | 1976-07-12 | 1978-01-26 | Henkel Kgaa | Kosmetische mittel mit einem gehalt an haut-feuchthaltemitteln |
| US4749563A (en) * | 1986-12-08 | 1988-06-07 | Charles Of The Ritz Group Ltd. | Moisture-resistant skin treatment compositions |
| US4911928A (en) * | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| FR2631824A1 (fr) * | 1988-05-31 | 1989-12-01 | Fourreau Jacques | Compositions cosmetiques pour les soins de la peau, du type creme anti-rides et masque |
| US4857321A (en) * | 1988-08-26 | 1989-08-15 | Thomas William C | Skin ointment |
| FR2644063B1 (fr) * | 1989-03-13 | 1991-06-14 | Fabre Pierre Cosmetique | Compositions dermatologiques et cosmetologiques a base d'alcoylcarboxamide et de sel de zinc utiles dans le traitement de la dermite seborrheique et/ou des troubles de la seborrhee |
| US5004599A (en) * | 1989-03-31 | 1991-04-02 | Scher Richard K | Method of treating nails |
| US5093360A (en) * | 1989-04-07 | 1992-03-03 | Yu Ruey J | Retinal, derivatives and their therapeutic use |
| US5124313A (en) * | 1989-06-02 | 1992-06-23 | Schaeffer Hans A | Methods of improved skin care and the treatment of dermatological conditions |
| US5043356A (en) * | 1990-01-19 | 1991-08-27 | Fulton Jr James E | Composition and method for rejuvenating skin using vitamin A propionate |
| US5057501A (en) * | 1990-03-13 | 1991-10-15 | Dermatologic Research Corporation | Methods for treatment of papulosquamous and eczematous diseases |
| FR2666347B1 (fr) * | 1990-08-31 | 1992-12-11 | Oreal | Compositions de lavage a base de silicones et procede de mise en óoeuvre. |
| US5492894A (en) * | 1991-03-21 | 1996-02-20 | The Procter & Gamble Company | Compositions for treating wrinkles comprising a peptide |
| BR9200951A (pt) * | 1991-03-21 | 1992-11-17 | Hoffmann La Roche | Compostos, processo para sua producao,preparacoes farmaceuticas e uso |
| FR2683721B1 (fr) * | 1991-11-15 | 1995-06-09 | Inocosm Laboratoires | Composition lipidique polaire permettant de vehiculer un agent actif et/ou de le faire penetrer dans une cellule cible. |
| US5750570A (en) * | 1992-03-31 | 1998-05-12 | The Regents Of The University Of Michigan | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
| AU4530493A (en) * | 1992-06-17 | 1994-01-04 | Procter & Gamble Company, The | Coolant compositions with reduced stinging |
| EP0582239B1 (de) * | 1992-08-04 | 1999-08-04 | Rhone-Poulenc Rorer Gmbh | Pharmazeutische und/oder kosmetische Zubereitung |
| MX9303557A (es) * | 1992-08-06 | 1994-03-31 | Beta Pharm Co | Metodo para la administracion de un antiandrogeno, en particular, espironolactona, a traves de la piel. |
| RU2026668C1 (ru) * | 1993-02-02 | 1995-01-20 | Болдина Ирина Михайловна | Крем для ухода за сухой увядающей кожей лица |
| GB9308103D0 (en) * | 1993-04-20 | 1993-06-02 | Unilever Plc | Cosmetic composition |
| US5599548A (en) * | 1995-05-08 | 1997-02-04 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides and retinol or retinyl ester |
| US5536740A (en) * | 1995-06-01 | 1996-07-16 | Elizabeth Arden Company, Division Of Conopco, Inc. | Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester |
-
1996
- 1996-09-27 US US08/722,539 patent/US5955092A/en not_active Expired - Lifetime
-
1997
- 1997-09-18 RU RU99108670/14A patent/RU2177780C2/ru active
- 1997-09-18 WO PCT/EP1997/005138 patent/WO1998013018A1/en not_active Ceased
- 1997-09-18 DE DE69718023T patent/DE69718023T2/de not_active Expired - Lifetime
- 1997-09-18 BR BRPI9711421-9A patent/BR9711421B1/pt not_active IP Right Cessation
- 1997-09-18 JP JP51523598A patent/JP3667772B2/ja not_active Expired - Lifetime
- 1997-09-18 EP EP97909294A patent/EP0929288B1/en not_active Expired - Lifetime
- 1997-09-18 ID IDW990132A patent/ID21922A/id unknown
- 1997-09-18 KR KR1019997002652A patent/KR100320137B1/ko not_active Expired - Fee Related
- 1997-09-18 AU AU47044/97A patent/AU714982B2/en not_active Ceased
- 1997-09-18 ES ES97909294T patent/ES2188903T3/es not_active Expired - Lifetime
- 1997-09-18 CZ CZ19991087A patent/CZ289857B6/cs not_active IP Right Cessation
- 1997-09-18 CN CN97199921A patent/CN1093757C/zh not_active Expired - Lifetime
- 1997-09-18 PL PL97332544A patent/PL188577B1/pl not_active IP Right Cessation
- 1997-09-18 CA CA002266925A patent/CA2266925C/en not_active Expired - Lifetime
- 1997-09-24 IN IN548BO1997 patent/IN189577B/en unknown
- 1997-09-26 ZA ZA978653A patent/ZA978653B/xx unknown
- 1997-09-29 AR ARP970104472A patent/AR009099A1/es active IP Right Grant
- 1997-12-16 TW TW086118982A patent/TW491706B/zh not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ300666B6 (cs) * | 1998-02-26 | 2009-07-15 | Unilever N. V. | Kosmetický prostredek k péci o pokožku |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4704497A (en) | 1998-04-17 |
| JP3667772B2 (ja) | 2005-07-06 |
| ES2188903T3 (es) | 2003-07-01 |
| IN189577B (OSRAM) | 2003-03-29 |
| BR9711421B1 (pt) | 2010-10-19 |
| CA2266925A1 (en) | 1998-04-02 |
| PL188577B1 (pl) | 2005-02-28 |
| KR100320137B1 (ko) | 2002-01-12 |
| PL332544A1 (en) | 1999-09-13 |
| CA2266925C (en) | 2003-12-09 |
| ID21922A (id) | 1999-08-12 |
| AR009099A1 (es) | 2000-03-08 |
| CN1093757C (zh) | 2002-11-06 |
| EP0929288A1 (en) | 1999-07-21 |
| WO1998013018A1 (en) | 1998-04-02 |
| US5955092A (en) | 1999-09-21 |
| DE69718023D1 (de) | 2003-01-30 |
| BR9711421A (pt) | 1999-08-24 |
| CZ108799A3 (cs) | 1999-08-11 |
| EP0929288B1 (en) | 2002-12-18 |
| CN1237898A (zh) | 1999-12-08 |
| AU714982B2 (en) | 2000-01-13 |
| TW491706B (en) | 2002-06-21 |
| KR20000048697A (ko) | 2000-07-25 |
| DE69718023T2 (de) | 2003-05-15 |
| RU2177780C2 (ru) | 2002-01-10 |
| ZA978653B (en) | 1999-03-26 |
| JP2000503029A (ja) | 2000-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic | ||
| MM4A | Patent lapsed due to non-payment of fee |
Effective date: 20120918 |