CZ281920B6 - Polycyklické guaninové deriváty - Google Patents

Polycyklické guaninové deriváty Download PDF

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Publication number
CZ281920B6
CZ281920B6 CS923749A CS374992A CZ281920B6 CZ 281920 B6 CZ281920 B6 CZ 281920B6 CS 923749 A CS923749 A CS 923749A CS 374992 A CS374992 A CS 374992A CZ 281920 B6 CZ281920 B6 CZ 281920B6
Authority
CZ
Czechia
Prior art keywords
purin
imidazo
phenylmethyl
hexahydro
dimethyl
Prior art date
Application number
CS923749A
Other languages
Czech (cs)
English (en)
Inventor
Bernard R. Neustadt
Neil A. Lindo
Kittrick Brian A. Mc
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of CZ374992A3 publication Critical patent/CZ374992A3/cs
Publication of CZ281920B6 publication Critical patent/CZ281920B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Filtering Materials (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
CS923749A 1990-06-21 1991-06-20 Polycyklické guaninové deriváty CZ281920B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54156890A 1990-06-21 1990-06-21
PCT/US1991/004154 WO1991019717A1 (en) 1990-06-21 1991-06-20 Polycyclic guanine derivatives

Publications (2)

Publication Number Publication Date
CZ374992A3 CZ374992A3 (en) 1993-10-13
CZ281920B6 true CZ281920B6 (cs) 1997-04-16

Family

ID=24160139

Family Applications (1)

Application Number Title Priority Date Filing Date
CS923749A CZ281920B6 (cs) 1990-06-21 1991-06-20 Polycyklické guaninové deriváty

Country Status (21)

Country Link
US (1) US5393755A (en:Method)
EP (1) EP0538332B1 (en:Method)
JP (1) JPH0747589B2 (en:Method)
KR (1) KR960004532B1 (en:Method)
AT (1) ATE155786T1 (en:Method)
AU (1) AU651607B2 (en:Method)
CA (1) CA2085733C (en:Method)
CZ (1) CZ281920B6 (en:Method)
DE (1) DE69126980T2 (en:Method)
FI (1) FI925731A7 (en:Method)
HU (1) HUT65623A (en:Method)
IE (1) IE912126A1 (en:Method)
IL (1) IL98559A0 (en:Method)
NO (1) NO924940L (en:Method)
NZ (1) NZ238609A (en:Method)
OA (1) OA09723A (en:Method)
PL (1) PL169481B1 (en:Method)
RU (1) RU2080322C1 (en:Method)
TW (1) TW197441B (en:Method)
WO (1) WO1991019717A1 (en:Method)
ZA (1) ZA914727B (en:Method)

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US6369092B1 (en) 1998-11-23 2002-04-09 Cell Pathways, Inc. Method for treating neoplasia by exposure to substituted benzimidazole derivatives
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US6077842A (en) * 1998-11-24 2000-06-20 Cell Pathways, Inc. Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives
US6034099A (en) * 1998-11-24 2000-03-07 Cell Pathways, Inc. Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones
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US6020379A (en) * 1999-02-19 2000-02-01 Cell Pathways, Inc. Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia
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EP1575916B1 (en) 2001-08-31 2013-05-22 The Rockefeller University Phosphodiesterase activity and regulation of phosphodiesterase 1-b-mediated signaling in brain
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CN101304977B (zh) 2005-11-09 2014-08-13 东曹株式会社 具有全氟烷基的核酸碱类和其制备方法
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Also Published As

Publication number Publication date
HUT65623A (en) 1994-07-28
OA09723A (en) 1993-08-30
IL98559A0 (en) 1992-07-15
AU651607B2 (en) 1994-07-28
NZ238609A (en) 1993-12-23
KR960004532B1 (ko) 1996-04-06
DE69126980D1 (de) 1997-09-04
IE912126A1 (en) 1992-01-01
TW197441B (en:Method) 1993-01-01
NO924940D0 (no) 1992-12-18
FI925731A0 (fi) 1992-12-17
FI925731A7 (fi) 1992-12-17
DE69126980T2 (de) 1998-01-08
ATE155786T1 (de) 1997-08-15
WO1991019717A1 (en) 1991-12-26
JPH05508647A (ja) 1993-12-02
CA2085733A1 (en) 1991-12-22
RU2080322C1 (ru) 1997-05-27
EP0538332A1 (en) 1993-04-28
US5393755A (en) 1995-02-28
PL169481B1 (pl) 1996-07-31
NO924940L (no) 1992-12-18
AU8199291A (en) 1992-01-07
EP0538332B1 (en) 1997-07-23
HU9204032D0 (en) 1993-03-29
JPH0747589B2 (ja) 1995-05-24
CA2085733C (en) 1996-03-05
CZ374992A3 (en) 1993-10-13
PL297299A1 (en:Method) 1992-07-13
ZA914727B (en) 1992-03-25

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