|
US7109003B2
(en)
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
|
EE05627B1
(et)
*
|
1998-12-23 |
2013-02-15 |
Pfizer Inc. |
CTLA-4 vastased inimese monoklonaalsed antikehad
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
US7357928B2
(en)
*
|
2002-04-08 |
2008-04-15 |
University Of Louisville Research Foundation, Inc. |
Method for the diagnosis and prognosis of malignant diseases
|
|
IL164287A0
(en)
*
|
2002-04-12 |
2005-12-18 |
Medarex Inc |
Methods of treatment using ctla-4 antibodies
|
|
ME00204B
(me)
|
2002-09-06 |
2011-02-10 |
Medarex Llc |
Terapijsko, humano, monoklonsko anti-il-1r1antitijelo
|
|
US20040197312A1
(en)
*
|
2003-04-02 |
2004-10-07 |
Marina Moskalenko |
Cytokine-expressing cellular vaccine combinations
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
CA2530172A1
(en)
|
2003-06-27 |
2005-02-10 |
Abgenix, Inc. |
Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof
|
|
MXPA06000798A
(es)
|
2003-07-22 |
2006-04-07 |
Schering Ag |
Anticuerpos de rg1 y usos de los mismos.
|
|
JP2007528721A
(ja)
|
2003-08-14 |
2007-10-18 |
ダイアックス コーポレイション |
エンドセリアーゼ−2リガンド
|
|
EP1515505A1
(en)
*
|
2003-09-12 |
2005-03-16 |
Siemens Aktiengesellschaft |
Reachability maintainance of a moving network based on temporary name identifiers
|
|
US20050136055A1
(en)
*
|
2003-12-22 |
2005-06-23 |
Pfizer Inc |
CD40 antibody formulation and methods
|
|
WO2005074633A2
(en)
*
|
2004-02-03 |
2005-08-18 |
The Regents Of The University Of Michigan |
Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
|
|
CA2560919A1
(en)
*
|
2004-03-26 |
2005-10-06 |
Pfizer Products Inc. |
Uses of anti-ctla-4 antibodies
|
|
US7785591B2
(en)
|
2004-10-14 |
2010-08-31 |
Morphosys Ag |
Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
|
|
JP2008518902A
(ja)
*
|
2004-11-04 |
2008-06-05 |
ファイザー・プロダクツ・インク |
乳癌のためのctla4抗体とアロマターゼ阻害剤の併用治療
|
|
WO2006096461A2
(en)
|
2005-03-08 |
2006-09-14 |
Pharmacia & Upjohn Company Llc |
Composition comprising an antibody against macrophage colony-stimulating factor (m-csf) and a chelating agent
|
|
TW200700082A
(en)
*
|
2005-03-23 |
2007-01-01 |
Pfizer Prod Inc |
Therapy of prostate cancer with ctla4 antibodies and hormonal therapy
|
|
EP1863532A1
(en)
*
|
2005-03-23 |
2007-12-12 |
Pfizer Products Incorporated |
Anti-ctla4 antibody and indolinone combination therapy for treatment of cancer
|
|
ES2720160T3
(es)
*
|
2005-05-09 |
2019-07-18 |
Ono Pharmaceutical Co |
Anticuerpos monoclonales humanos contra muerte programada 1(PD-1) y métodos para tratar el cáncer usando anticuerpos dirigidos contra PD-1 solos o junto con otras sustancias inmunoterapéuticas
|
|
CN104436190A
(zh)
|
2005-06-08 |
2015-03-25 |
达纳-法伯癌症研究院公司 |
通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物
|
|
US20090117132A1
(en)
*
|
2005-07-07 |
2009-05-07 |
Pfizer, Inc. |
Anti-Ctla-4 Antibody and Cpg-Motif-Containing Synthetic Oligodeoxynucleotide Combination Therapy for Cancer Treatment
|
|
AU2006321593B2
(en)
|
2005-12-07 |
2012-10-04 |
E. R. Squibb & Sons, L.L.C. |
CTLA-4 antibody dosage escalation regimens
|
|
CA2647282A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Pfizer Products Inc. |
Ctla4 antibody combination therapy
|
|
JP2010534719A
(ja)
*
|
2007-07-27 |
2010-11-11 |
ファイザー・リミテッド |
沈殿化による抗体精製方法
|
|
KR101666228B1
(ko)
|
2007-09-28 |
2016-10-13 |
인트렉손 코포레이션 |
생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도
|
|
RU2373836C2
(ru)
*
|
2007-12-18 |
2009-11-27 |
Федеральное государственное учреждение "Научно-исследовательский институт онкологии имени Н.Н. Петрова Федерального агентства по высокотехнологичной медицинской помощи" |
Способ оптимизации лечебной тактики при лимфоме ходжкина у детей и подростков
|
|
ES2558568T3
(es)
*
|
2008-01-08 |
2016-02-05 |
Bristol-Myers Squibb Company |
Combinación de anticuerpo anti-CTLA4 con agentes moduladores de la tubulina para el tratamiento de enfermedades proliferativas
|
|
US8119129B2
(en)
|
2008-08-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Combination of anti-CTLA4 antibody with dasatinib for the treatment of proliferative diseases
|
|
LT2769737T
(lt)
*
|
2009-07-20 |
2017-06-26 |
Bristol-Myers Squibb Company |
Anti-ctla4 antikūno derinys su etopozidu, skirtas sinerginiam proliferacinių ligų gydymui
|
|
RU2421217C2
(ru)
*
|
2009-09-03 |
2011-06-20 |
Учреждение Российской академии медицинских наук Гематологический научный центр РАМН (ГНЦ РАМН) |
Способ дифференцированного лечения диффузных в-крупноклеточных лимфосарком лимфоидных органов взрослых
|
|
US20140178368A1
(en)
|
2011-04-19 |
2014-06-26 |
Leslie Lynne SHARP |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
|
WO2012167173A1
(en)
|
2011-06-02 |
2012-12-06 |
The University Of Louisville Research Foundation, Inc. |
Anti-nucleolin agent-conjugated nanoparticles
|
|
BR112014018964A2
(pt)
|
2012-03-13 |
2020-05-12 |
F. Hoffmann-La Roche Ag |
Anticorpo anti-vegf e uso de um anticorpo anti-vegf
|
|
CA2871711A1
(en)
|
2012-05-04 |
2013-11-07 |
Pfizer Inc. |
Prostate-associated antigens and vaccine-based immunotherapy regimens
|
|
TR201900694T4
(tr)
*
|
2012-08-23 |
2019-02-21 |
Agensys Inc |
158p1d7 proteinlerine bağlanan antikor ilaç konjugatları (adc).
|
|
WO2014089113A1
(en)
*
|
2012-12-03 |
2014-06-12 |
Bristol-Myers Squibb Company |
Enhancing anti-cancer activity of immunomodulatory fc fusion proteins
|
|
PT3030262T
(pt)
|
2013-08-08 |
2019-12-11 |
Inst Gustave Roussy Igr |
Composição farmacêutica de associação
|
|
CN105612175B
(zh)
|
2013-08-08 |
2023-05-09 |
赛腾制药 |
基于IL-15和IL-15Rαsushi结构域的调节因子
|
|
CN105636986B
(zh)
*
|
2013-10-18 |
2020-05-12 |
瑞泽恩制药公司 |
包含vegf拮抗剂和抗-ctla-4抗体的组合的方法和组合物
|
|
JP6712952B2
(ja)
*
|
2014-03-31 |
2020-06-24 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
固形腫瘍悪性病変を処置するための、抗ctla−4抗体および/または抗pd−1抗体と組み合わせた、細菌、細菌産物、および他の免疫調節性実体の使用
|
|
JP6634625B2
(ja)
*
|
2014-05-01 |
2020-01-22 |
株式会社アネロファーマ・サイエンス |
異種ポリペプチド発現カセット
|
|
AU2015266958A1
(en)
|
2014-05-28 |
2016-12-08 |
Agenus Inc. |
Anti-GITR antibodies and methods of use thereof
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
HUE043847T2
(hu)
|
2014-08-28 |
2019-09-30 |
Halozyme Inc |
Hialuronán-lebontó enzimmel és egy immun checkpoint inhibitorral végzett kombinációs terápia
|
|
WO2016057367A1
(en)
|
2014-10-06 |
2016-04-14 |
Dana-Farber Cancer Institute, Inc. |
Angiopoietin-2 biomarkers predictive of anti-immune checkpoint response
|
|
CN108064282A
(zh)
|
2014-10-14 |
2018-05-22 |
哈洛齐梅公司 |
腺苷脱氨酶-2(ada2)、其变体的组合物及使用其的方法
|
|
LT3240801T
(lt)
|
2014-12-31 |
2021-02-25 |
Checkmate Pharmaceuticals, Inc. |
Kombinuota navikų imunoterapija
|
|
CA2976446A1
(en)
*
|
2015-02-13 |
2016-08-18 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind ctla4
|
|
WO2016179394A1
(en)
|
2015-05-05 |
2016-11-10 |
Malik Mohammad Tariq |
Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents
|
|
SI3303394T1
(sl)
*
|
2015-05-29 |
2020-10-30 |
Agenus Inc. |
Protitelesa proti-CTLA-4 in postopki njihove uporabe
|
|
CA2993177A1
(en)
*
|
2015-07-22 |
2017-01-26 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind lag3
|
|
WO2017031157A1
(en)
*
|
2015-08-18 |
2017-02-23 |
Mateon Therapeutics, Inc. |
Use of vdas to enhance immunomodulating therapies against tumors
|
|
SG10201912984WA
(en)
|
2015-12-02 |
2020-03-30 |
Agenus Inc |
Antibodies and methods of use thereof
|
|
US11760803B2
(en)
|
2016-03-24 |
2023-09-19 |
Takeda Pharmaceutical Company Limited |
Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
|
|
WO2017165742A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments
|
|
WO2017173334A1
(en)
|
2016-04-01 |
2017-10-05 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
|
EA039322B1
(ru)
*
|
2016-04-15 |
2022-01-13 |
Эйдженус Инк. |
Антитела против ctla-4 и способы их применения
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
EP3505183B1
(en)
*
|
2016-08-26 |
2022-03-30 |
Tetsuji Okuno |
Microvascular blood flow decreasing agent and use thereof
|
|
US11013802B2
(en)
*
|
2016-12-07 |
2021-05-25 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
CN118634323A
(zh)
|
2016-12-07 |
2024-09-13 |
艾吉纳斯公司 |
抗体和其使用方法
|
|
CA3089768A1
(en)
|
2018-02-02 |
2019-08-08 |
Oncoimmune, Inc. |
Mutant anti-ctla-4 antibodies with improved immunotherapeutic effect but attenuated adverse effects
|
|
US12246031B2
(en)
|
2018-02-13 |
2025-03-11 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
CN112218892B
(zh)
*
|
2018-03-19 |
2023-04-25 |
上海药明生物技术有限公司 |
新型抗ctla-4抗体多肽
|
|
MX2020010410A
(es)
|
2018-04-09 |
2021-01-15 |
Checkmate Pharmaceuticals |
Empaquetado de oligonucleotidos en particulas similares a virus.
|
|
EP3820992A2
(en)
|
2018-07-11 |
2021-05-19 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
|
CN110092826B
(zh)
*
|
2019-02-28 |
2022-04-15 |
天津大学 |
CTLA-4类似物CFN13及CFN13-Fc基因和蛋白
|
|
CN115803343A
(zh)
*
|
2020-05-26 |
2023-03-14 |
百奥泰生物制药股份有限公司 |
多特异性抗体及其应用
|
|
CN116113406B
(zh)
|
2020-07-10 |
2025-08-29 |
密歇根大学董事会 |
Gas41抑制剂及其使用方法
|
|
EP4343004A3
(en)
|
2020-10-19 |
2024-09-11 |
Dana-Farber Cancer Institute, Inc. |
Germline biomarkers of clinical response and benefit to immune checkpoint inhibitor therapy
|
|
EP4326321A1
(en)
|
2021-04-20 |
2024-02-28 |
Institut Curie |
Compositions and methods for use in immunotherapy
|