CY2552B1 - Synthetic peptide analogs of lung surfactant protein SP-C - Google Patents
Synthetic peptide analogs of lung surfactant protein SP-CInfo
- Publication number
- CY2552B1 CY2552B1 CY0600006A CY0600006A CY2552B1 CY 2552 B1 CY2552 B1 CY 2552B1 CY 0600006 A CY0600006 A CY 0600006A CY 0600006 A CY0600006 A CY 0600006A CY 2552 B1 CY2552 B1 CY 2552B1
- Authority
- CY
- Cyprus
- Prior art keywords
- pct
- image
- surfactant protein
- lung surfactant
- synthetic peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4418936A DE4418936A1 (de) | 1994-05-31 | 1994-05-31 | Polypeptid |
Publications (1)
Publication Number | Publication Date |
---|---|
CY2552B1 true CY2552B1 (en) | 2008-07-02 |
Family
ID=6519392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY0600006A CY2552B1 (en) | 1994-05-31 | 2006-02-20 | Synthetic peptide analogs of lung surfactant protein SP-C |
Country Status (29)
Country | Link |
---|---|
US (1) | US5874406A (fr) |
EP (1) | EP0764172B1 (fr) |
JP (1) | JP3359638B2 (fr) |
KR (1) | KR100355626B1 (fr) |
CN (1) | CN1130374C (fr) |
AT (1) | ATE275154T1 (fr) |
AU (1) | AU690280B2 (fr) |
BG (1) | BG63210B1 (fr) |
BR (1) | BR9507811B1 (fr) |
CA (1) | CA2191344C (fr) |
CY (1) | CY2552B1 (fr) |
CZ (1) | CZ286976B6 (fr) |
DE (2) | DE4418936A1 (fr) |
DK (1) | DK0764172T3 (fr) |
EE (1) | EE03775B1 (fr) |
ES (1) | ES2227548T3 (fr) |
FI (1) | FI118126B (fr) |
HK (1) | HK1000891A1 (fr) |
HU (1) | HU220191B (fr) |
NO (1) | NO317149B1 (fr) |
NZ (1) | NZ287447A (fr) |
PL (1) | PL181234B1 (fr) |
PT (1) | PT764172E (fr) |
RO (1) | RO118752B1 (fr) |
RU (1) | RU2145611C1 (fr) |
SI (1) | SI0764172T1 (fr) |
SK (1) | SK282441B6 (fr) |
UA (1) | UA35636C2 (fr) |
WO (1) | WO1995032992A1 (fr) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2322097A (en) * | 1996-03-27 | 1997-10-17 | Ortho Pharmaceutical Corporation | Lyophilized pulmonary surfactant peptide compositions |
DE19851119C2 (de) | 1998-11-06 | 2001-05-31 | Byk Gulden Lomberg Chem Fab | Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung |
IT1308180B1 (it) * | 1999-02-12 | 2001-12-07 | Chiesi Farma Spa | Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante |
AU5400000A (en) * | 1999-06-11 | 2001-01-02 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c) |
EP1192184B1 (fr) * | 1999-06-17 | 2007-01-03 | ALTANA Pharma AG | Esters de proteine c tensioactifs |
EP1216052A1 (fr) | 1999-09-16 | 2002-06-26 | Byk Gulden Lomberg Chemische Fabrik GmbH | Combinaison de c1-inh et d'un agent tensioactif pulmonaire pour le traitement des troubles respiratoires |
WO2001039573A2 (fr) * | 1999-12-01 | 2001-06-07 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Utilisation nouvelle d'agent tensio-actif du poumon |
JP2003522138A (ja) * | 2000-02-11 | 2003-07-22 | アルタナ ファルマ アクチエンゲゼルシャフト | 慢性肺疾患の予防および治療のための肺表面活性剤の新規使用 |
US6660833B1 (en) | 2000-02-29 | 2003-12-09 | Harbor-Ucla Research And Education Institute | Respiratory distress syndrome therapy with peptide analogs of human SP-B |
DE10018022A1 (de) * | 2000-04-12 | 2001-10-31 | Byk Gulden Lomberg Chem Fab | Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen |
US20040254112A1 (en) * | 2000-04-12 | 2004-12-16 | Dietrich Hafner | Use of pulmonary surfactant for the early treatment of acute pulmonary diseases |
PT1276495E (pt) * | 2000-04-12 | 2006-08-31 | Altana Pharma Ag | Utilizacao de tensioactivo pulmonar recombinante para o tratamento precoce de doencas pulmonares agudas |
AU2002338882B2 (en) | 2001-10-11 | 2008-04-03 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Novel use of pulmonary surfactant |
WO2003053455A1 (fr) | 2001-12-12 | 2003-07-03 | Penn State Research Foundation | Surfactants destines au traitement de la fibrose pulmonaire |
ATE457736T1 (de) * | 2004-08-06 | 2010-03-15 | Nycomed Gmbh | Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid |
US7464012B2 (en) * | 2004-12-10 | 2008-12-09 | L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude | Simplified process simulator |
US7582312B2 (en) * | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
US8337815B2 (en) | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
JP2008526868A (ja) | 2005-01-06 | 2008-07-24 | ディスカバリー ラボラトリーズ,インコーポレイテッド | 表面活性剤処置療法 |
DE102005014650B3 (de) * | 2005-03-31 | 2006-08-17 | Altana Pharma Ag | Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters |
DE102005016229B3 (de) | 2005-04-08 | 2006-06-14 | Altana Pharma Ag | Trockenvernebler |
MX2009003002A (es) * | 2006-09-19 | 2009-06-01 | Discovery Lab Inc | Formulaciones de tensioactivos pulmonares y metodos para promover la aclaracion del moco. |
US7951781B2 (en) | 2006-11-02 | 2011-05-31 | University Of Iowa Research Foundation | Methods and compositions related to PLUNC surfactant polypeptides |
EP2009023A1 (fr) * | 2007-06-04 | 2008-12-31 | Rentschler Beteiligungs GmbH | Nouveaux peptides et leur utilisation pour le traitement de l'oedème |
US8048043B2 (en) | 2007-06-08 | 2011-11-01 | Chiesi Farmaceutici S. P. A. | Method of administration of a pulmonary surfactant |
CN102271666A (zh) | 2008-12-10 | 2011-12-07 | Paka肺部医药公司 | 用于向肺脏递送药物的方法和组合物 |
CA2773490A1 (fr) | 2009-09-08 | 2011-03-17 | Chiesi Farmaceutici S.P.A. | Combinaison therapeutique comprenant un tensioactif pulmonaire et des enzymes antioxydants |
CN103052380B (zh) | 2010-08-23 | 2015-11-25 | 塔科达有限责任公司 | 包含治疗活性物质的湿润颗粒 |
US9815869B2 (en) * | 2012-02-09 | 2017-11-14 | University Of Rochester | SP-B and SP-C peptides, synthetic lung surfactants, and use thereof |
US20130303726A1 (en) * | 2012-04-17 | 2013-11-14 | Chiesi Farmaceutici S.P.A. | Method for the preparation of surfactant peptides |
WO2013188016A2 (fr) | 2012-05-04 | 2013-12-19 | Discovery Laboratories, Inc. | Thérapie utilisant des surfactants pour exposition à un rayonnement ionisant |
RU2687776C2 (ru) | 2014-03-05 | 2019-05-16 | Фраунхофер-Гезельшафт Цур Фордерунг Дер Ангевандтен Форшунг Е.В. | Увлажнитель для увлажнения аэрозоля |
EP3106090A1 (fr) | 2015-06-15 | 2016-12-21 | CHIESI FARMACEUTICI S.p.A. | Système pour une administration efficace, synchronisée avec la respiration, d'un médicament aux poumons |
US20180110948A1 (en) | 2015-04-22 | 2018-04-26 | Chiesi Farmaceutici S.P.A | Method and system for effective breath-synchronized delivery of medicament to the lungs |
US11311691B2 (en) | 2015-04-28 | 2022-04-26 | Chiesi Farmaceutici S.P.A | Device for facilitating the administration of a medicament to the lung by a catheter |
JP2018514545A (ja) | 2015-04-30 | 2018-06-07 | ユニバーシティ オブ ブレーメン | 医療用および美容用の新規な皮膚ケア製造物 |
CN109496159A (zh) | 2016-07-28 | 2019-03-19 | 奇斯药制品公司 | 用于递送雾化药剂的方法和系统 |
US11524131B2 (en) | 2016-10-26 | 2022-12-13 | Chiesi Farmaceutici S.P.A. | Device for facilitating the administration of a medicament to the lung by a catheter |
EP3558376B1 (fr) | 2016-12-22 | 2021-10-20 | Chiesi Farmaceutici S.p.A. | Combinaison thérapeutique comprenant un tensioactif pulmonaire et un stéroïde pour le traitement de la dysplasie bronchopulmonaire évolutive |
CN107163148A (zh) * | 2017-05-15 | 2017-09-15 | 重庆理工大学 | 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用 |
WO2019115771A1 (fr) | 2017-12-15 | 2019-06-20 | Pari Pharma Gmbh | Système de nébuliseur, système de maintien, combinaison comprenant un système de nébuliseur et un système de maintien, et procédé d'administration d'aérosol |
TW201927286A (zh) | 2017-12-15 | 2019-07-16 | 義大利商凱西製藥公司 | 用於噴霧投藥之包含肺表面張力素的藥學調配物 |
AU2019260526A1 (en) | 2018-04-23 | 2020-11-19 | Chiesi Farmaceutici S.P.A. | A therapeutic combination comprising a pulmonary surfactant and a steroid for the prophylaxis of BPD |
CN109001466A (zh) * | 2018-07-19 | 2018-12-14 | 新疆维吾尔自治区人民医院 | 一种用于osa的肺表面活性蛋白试剂盒及其应用 |
EP3666316A1 (fr) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Dispositif d'administration d'aérosol et procédé pour faire fonctionner un dispositif d'administration d'aérosol |
EP3666315A1 (fr) | 2018-12-14 | 2020-06-17 | PARI Pharma GmbH | Dispositif d'administration d'aérosol et procédé de fonctionnement du dispositif d'administration d'aérosol |
EP3843105A1 (fr) | 2019-12-23 | 2021-06-30 | PARI Pharma GmbH | Dispositif de commande pour système nébuliseur d'aérosol |
WO2021151853A1 (fr) | 2020-01-28 | 2021-08-05 | Chiesi Farmaceutici S.P.A. | Polypeptides ayant des propriétés améliorées |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
US4933280A (en) * | 1984-12-11 | 1990-06-12 | California Biotechnology Inc. | Recombinant DNA sequence encoding Alveolar Surfactant Protein |
US5169761A (en) * | 1984-12-11 | 1992-12-08 | California Biotechnology Inc. | Dna encoding and expression systems for alveolar surfactant proteins |
US5104853A (en) * | 1984-12-11 | 1992-04-14 | California Biotechnology Inc. | Alveolar surfactant proteins having cys to ser mutations |
US4659805A (en) * | 1984-12-11 | 1987-04-21 | California Biotechnology, Inc. | Recombinant alveolar surfactant protein |
US5013720A (en) * | 1986-05-06 | 1991-05-07 | Abbott Laboratories | SAP-6-Val proteins and methods |
EP0383837B1 (fr) * | 1987-11-04 | 1998-02-04 | Byk Gulden Lomberg Chemische Fabrik GmbH | Proteines a effet tensio-actif alveolaire |
SE8803713D0 (sv) * | 1988-10-18 | 1988-10-18 | Kabigen Ab | Biologically active lipoprotein and its use |
DE3921954A1 (de) * | 1989-07-04 | 1991-01-17 | Thomae Gmbh Dr K | Niedrig-viskose, hochkonzentrierte surfactant-suspension |
JPH05294996A (ja) * | 1992-04-17 | 1993-11-09 | Tokyo Tanabe Co Ltd | 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤 |
-
1994
- 1994-05-31 DE DE4418936A patent/DE4418936A1/de not_active Withdrawn
-
1995
- 1995-05-27 CA CA002191344A patent/CA2191344C/fr not_active Expired - Lifetime
- 1995-05-27 WO PCT/EP1995/002028 patent/WO1995032992A1/fr active IP Right Grant
- 1995-05-27 PT PT95920906T patent/PT764172E/pt unknown
- 1995-05-27 US US08/750,194 patent/US5874406A/en not_active Expired - Lifetime
- 1995-05-27 AT AT95920906T patent/ATE275154T1/de active
- 1995-05-27 KR KR1019960706778A patent/KR100355626B1/ko not_active IP Right Cessation
- 1995-05-27 HU HU9603249A patent/HU220191B/hu unknown
- 1995-05-27 SI SI9530712T patent/SI0764172T1/xx unknown
- 1995-05-27 CZ CZ19963502A patent/CZ286976B6/cs not_active IP Right Cessation
- 1995-05-27 ES ES95920906T patent/ES2227548T3/es not_active Expired - Lifetime
- 1995-05-27 RO RO96-02248A patent/RO118752B1/ro unknown
- 1995-05-27 RU RU96124768A patent/RU2145611C1/ru active
- 1995-05-27 NZ NZ287447A patent/NZ287447A/en not_active IP Right Cessation
- 1995-05-27 BR BRPI9507811-8A patent/BR9507811B1/pt not_active IP Right Cessation
- 1995-05-27 EE EE9600175A patent/EE03775B1/xx unknown
- 1995-05-27 SK SK1524-96A patent/SK282441B6/sk not_active IP Right Cessation
- 1995-05-27 DK DK95920906T patent/DK0764172T3/da active
- 1995-05-27 PL PL95317420A patent/PL181234B1/pl unknown
- 1995-05-27 UA UA96114479A patent/UA35636C2/uk unknown
- 1995-05-27 DE DE59510941T patent/DE59510941D1/de not_active Expired - Lifetime
- 1995-05-27 AU AU26169/95A patent/AU690280B2/en not_active Expired
- 1995-05-27 JP JP50030596A patent/JP3359638B2/ja not_active Expired - Lifetime
- 1995-05-27 CN CN95194374A patent/CN1130374C/zh not_active Expired - Lifetime
- 1995-05-27 EP EP95920906A patent/EP0764172B1/fr not_active Expired - Lifetime
-
1996
- 1996-11-27 NO NO19965052A patent/NO317149B1/no not_active IP Right Cessation
- 1996-11-29 FI FI964766A patent/FI118126B/fi not_active IP Right Cessation
- 1996-12-04 BG BG101028A patent/BG63210B1/bg unknown
-
1997
- 1997-12-18 HK HK97102503A patent/HK1000891A1/xx not_active IP Right Cessation
-
2006
- 2006-02-20 CY CY0600006A patent/CY2552B1/xx unknown
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