CY2552B1 - Synthetic peptide analogs of lung surfactant protein SP-C - Google Patents

Synthetic peptide analogs of lung surfactant protein SP-C

Info

Publication number
CY2552B1
CY2552B1 CY0600006A CY0600006A CY2552B1 CY 2552 B1 CY2552 B1 CY 2552B1 CY 0600006 A CY0600006 A CY 0600006A CY 0600006 A CY0600006 A CY 0600006A CY 2552 B1 CY2552 B1 CY 2552B1
Authority
CY
Cyprus
Prior art keywords
pct
image
surfactant protein
lung surfactant
synthetic peptide
Prior art date
Application number
CY0600006A
Other languages
English (en)
Inventor
Ruediger Nave
Wolf-Ruediger Ulrich
Ernst Sturm
Uwe Krueger
Dietrich Haefner
Klaus P Schaefer
Klaus Melchers
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6519392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2552(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of CY2552B1 publication Critical patent/CY2552B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CY0600006A 1994-05-31 2006-02-20 Synthetic peptide analogs of lung surfactant protein SP-C CY2552B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4418936A DE4418936A1 (de) 1994-05-31 1994-05-31 Polypeptid

Publications (1)

Publication Number Publication Date
CY2552B1 true CY2552B1 (en) 2008-07-02

Family

ID=6519392

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0600006A CY2552B1 (en) 1994-05-31 2006-02-20 Synthetic peptide analogs of lung surfactant protein SP-C

Country Status (29)

Country Link
US (1) US5874406A (fr)
EP (1) EP0764172B1 (fr)
JP (1) JP3359638B2 (fr)
KR (1) KR100355626B1 (fr)
CN (1) CN1130374C (fr)
AT (1) ATE275154T1 (fr)
AU (1) AU690280B2 (fr)
BG (1) BG63210B1 (fr)
BR (1) BR9507811B1 (fr)
CA (1) CA2191344C (fr)
CY (1) CY2552B1 (fr)
CZ (1) CZ286976B6 (fr)
DE (2) DE4418936A1 (fr)
DK (1) DK0764172T3 (fr)
EE (1) EE03775B1 (fr)
ES (1) ES2227548T3 (fr)
FI (1) FI118126B (fr)
HK (1) HK1000891A1 (fr)
HU (1) HU220191B (fr)
NO (1) NO317149B1 (fr)
NZ (1) NZ287447A (fr)
PL (1) PL181234B1 (fr)
PT (1) PT764172E (fr)
RO (1) RO118752B1 (fr)
RU (1) RU2145611C1 (fr)
SI (1) SI0764172T1 (fr)
SK (1) SK282441B6 (fr)
UA (1) UA35636C2 (fr)
WO (1) WO1995032992A1 (fr)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2322097A (en) * 1996-03-27 1997-10-17 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
DE19851119C2 (de) 1998-11-06 2001-05-31 Byk Gulden Lomberg Chem Fab Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
AU5400000A (en) * 1999-06-11 2001-01-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
EP1192184B1 (fr) * 1999-06-17 2007-01-03 ALTANA Pharma AG Esters de proteine c tensioactifs
EP1216052A1 (fr) 1999-09-16 2002-06-26 Byk Gulden Lomberg Chemische Fabrik GmbH Combinaison de c1-inh et d'un agent tensioactif pulmonaire pour le traitement des troubles respiratoires
WO2001039573A2 (fr) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Utilisation nouvelle d'agent tensio-actif du poumon
JP2003522138A (ja) * 2000-02-11 2003-07-22 アルタナ ファルマ アクチエンゲゼルシャフト 慢性肺疾患の予防および治療のための肺表面活性剤の新規使用
US6660833B1 (en) 2000-02-29 2003-12-09 Harbor-Ucla Research And Education Institute Respiratory distress syndrome therapy with peptide analogs of human SP-B
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
US20040254112A1 (en) * 2000-04-12 2004-12-16 Dietrich Hafner Use of pulmonary surfactant for the early treatment of acute pulmonary diseases
PT1276495E (pt) * 2000-04-12 2006-08-31 Altana Pharma Ag Utilizacao de tensioactivo pulmonar recombinante para o tratamento precoce de doencas pulmonares agudas
AU2002338882B2 (en) 2001-10-11 2008-04-03 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Novel use of pulmonary surfactant
WO2003053455A1 (fr) 2001-12-12 2003-07-03 Penn State Research Foundation Surfactants destines au traitement de la fibrose pulmonaire
ATE457736T1 (de) * 2004-08-06 2010-03-15 Nycomed Gmbh Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
JP2008526868A (ja) 2005-01-06 2008-07-24 ディスカバリー ラボラトリーズ，インコーポレイテッド 表面活性剤処置療法
DE102005014650B3 (de) * 2005-03-31 2006-08-17 Altana Pharma Ag Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters
DE102005016229B3 (de) 2005-04-08 2006-06-14 Altana Pharma Ag Trockenvernebler
MX2009003002A (es) * 2006-09-19 2009-06-01 Discovery Lab Inc Formulaciones de tensioactivos pulmonares y metodos para promover la aclaracion del moco.
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
EP2009023A1 (fr) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Nouveaux peptides et leur utilisation pour le traitement de l'oedème
US8048043B2 (en) 2007-06-08 2011-11-01 Chiesi Farmaceutici S. P. A. Method of administration of a pulmonary surfactant
CN102271666A (zh) 2008-12-10 2011-12-07 Paka肺部医药公司 用于向肺脏递送药物的方法和组合物
CA2773490A1 (fr) 2009-09-08 2011-03-17 Chiesi Farmaceutici S.P.A. Combinaison therapeutique comprenant un tensioactif pulmonaire et des enzymes antioxydants
CN103052380B (zh) 2010-08-23 2015-11-25 塔科达有限责任公司 包含治疗活性物质的湿润颗粒
US9815869B2 (en) * 2012-02-09 2017-11-14 University Of Rochester SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
WO2013188016A2 (fr) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Thérapie utilisant des surfactants pour exposition à un rayonnement ionisant
RU2687776C2 (ru) 2014-03-05 2019-05-16 Фраунхофер-Гезельшафт Цур Фордерунг Дер Ангевандтен Форшунг Е.В. Увлажнитель для увлажнения аэрозоля
EP3106090A1 (fr) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. Système pour une administration efficace, synchronisée avec la respiration, d'un médicament aux poumons
US20180110948A1 (en) 2015-04-22 2018-04-26 Chiesi Farmaceutici S.P.A Method and system for effective breath-synchronized delivery of medicament to the lungs
US11311691B2 (en) 2015-04-28 2022-04-26 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
JP2018514545A (ja) 2015-04-30 2018-06-07 ユニバーシティ オブ ブレーメン 医療用および美容用の新規な皮膚ケア製造物
CN109496159A (zh) 2016-07-28 2019-03-19 奇斯药制品公司 用于递送雾化药剂的方法和系统
US11524131B2 (en) 2016-10-26 2022-12-13 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
EP3558376B1 (fr) 2016-12-22 2021-10-20 Chiesi Farmaceutici S.p.A. Combinaison thérapeutique comprenant un tensioactif pulmonaire et un stéroïde pour le traitement de la dysplasie bronchopulmonaire évolutive
CN107163148A (zh) * 2017-05-15 2017-09-15 重庆理工大学 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用
WO2019115771A1 (fr) 2017-12-15 2019-06-20 Pari Pharma Gmbh Système de nébuliseur, système de maintien, combinaison comprenant un système de nébuliseur et un système de maintien, et procédé d'administration d'aérosol
TW201927286A (zh) 2017-12-15 2019-07-16 義大利商凱西製藥公司 用於噴霧投藥之包含肺表面張力素的藥學調配物
AU2019260526A1 (en) 2018-04-23 2020-11-19 Chiesi Farmaceutici S.P.A. A therapeutic combination comprising a pulmonary surfactant and a steroid for the prophylaxis of BPD
CN109001466A (zh) * 2018-07-19 2018-12-14 新疆维吾尔自治区人民医院 一种用于osa的肺表面活性蛋白试剂盒及其应用
EP3666316A1 (fr) 2018-12-14 2020-06-17 PARI Pharma GmbH Dispositif d'administration d'aérosol et procédé pour faire fonctionner un dispositif d'administration d'aérosol
EP3666315A1 (fr) 2018-12-14 2020-06-17 PARI Pharma GmbH Dispositif d'administration d'aérosol et procédé de fonctionnement du dispositif d'administration d'aérosol
EP3843105A1 (fr) 2019-12-23 2021-06-30 PARI Pharma GmbH Dispositif de commande pour système nébuliseur d'aérosol
WO2021151853A1 (fr) 2020-01-28 2021-08-05 Chiesi Farmaceutici S.P.A. Polypeptides ayant des propriétés améliorées

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
EP0383837B1 (fr) * 1987-11-04 1998-02-04 Byk Gulden Lomberg Chemische Fabrik GmbH Proteines a effet tensio-actif alveolaire
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤

Also Published As

Publication number Publication date
US5874406A (en) 1999-02-23
NO965052L (no) 1997-01-28
HU9603249D0 (en) 1997-01-28
ES2227548T3 (es) 2005-04-01
PL317420A1 (en) 1997-04-14
SI0764172T1 (en) 2005-02-28
HU220191B (hu) 2001-11-28
FI118126B (fi) 2007-07-13
CN1154117A (zh) 1997-07-09
AU690280B2 (en) 1998-04-23
MX9605986A (es) 1998-06-30
BG63210B1 (bg) 2001-06-29
KR970703367A (ko) 1997-07-03
BG101028A (en) 1998-01-30
DE59510941D1 (de) 2004-10-07
CN1130374C (zh) 2003-12-10
DE4418936A1 (de) 1996-02-08
PL181234B1 (pl) 2001-06-29
NZ287447A (en) 1998-01-26
RU2145611C1 (ru) 2000-02-20
JP3359638B2 (ja) 2002-12-24
CA2191344A1 (fr) 1995-12-07
EE9600175A (et) 1997-06-16
NO317149B1 (no) 2004-08-30
HUT76952A (hu) 1998-01-28
UA35636C2 (uk) 2001-04-16
HK1000891A1 (en) 2004-09-17
FI964766A (fi) 1996-11-29
DK0764172T3 (da) 2005-01-10
RO118752B1 (ro) 2003-10-30
CZ350296A3 (en) 1997-05-14
SK152496A3 (en) 1997-06-04
EP0764172A1 (fr) 1997-03-26
PT764172E (pt) 2005-01-31
BR9507811B1 (pt) 2009-05-05
JPH10504025A (ja) 1998-04-14
NO965052D0 (no) 1996-11-27
CA2191344C (fr) 2003-04-08
ATE275154T1 (de) 2004-09-15
KR100355626B1 (ko) 2002-12-26
EE03775B1 (et) 2002-06-17
WO1995032992A1 (fr) 1995-12-07
CZ286976B6 (en) 2000-08-16
SK282441B6 (sk) 2002-02-05
EP0764172B1 (fr) 2004-09-01
FI964766A0 (fi) 1996-11-29
AU2616995A (en) 1995-12-21
BR9507811A (pt) 1997-09-16

Similar Documents

Publication Publication Date Title
CY2552B1 (en) Synthetic peptide analogs of lung surfactant protein SP-C
AU4188789A (en) Urethane-protected amino acid-n-carboxyanhydrides
CA2024651A1 (fr) Preparation transvaginale hautement absorbable contenant un polypeptide biologiquement actif
DK193887D0 (da) Fysiologisk aktivt peptid
TR199501630A2 (tr) Peptid p277 benzerleri ve diagnoz ve dibetlerin'lerin tedavisi icin onlari iceren kompozisyonlar.
HUT77289A (hu) Az N-terminálison szulfonil- vagy szulfamoil-csoportokat tartalmazó dipeptid-(p-amido-benzil)-amidok
GR852541B (fr)
DE3569541D1 (en) Pharmacologically active peptides
GR3001922T3 (en) Use of n,n'-bis-l-amino acid-l-cystin peptides in amino acid preparations for oral and parenteral administration
EP0783524A4 (fr) Peptides et compositions pharmaceutiques les contenant
EP0490383A3 (en) Peptides of the hiv-gag protein, their preparation and use
AU7052191A (en) Antitumoral composition based on polypeptides having human interleukin 2 activity
JPS649938A (en) Oral ingestive composition
CA2004764A1 (fr) Proteines ancrod, leur preparation et leur utilisation
AU2065488A (en) The preparation of antigens of human immunodeficiency virus type 1, and the use thereof as diagnostic and therapeutic agent
AU7627987A (en) Use of 2-aminoalkyl-5-pyridinols as nootropic agents and anti-depressants
DE3689850D1 (de) Peptide und deren Verwendung in der Therapie.
HUT60145A (en) Process for producing pharmaceutical composition comprising human interleukin-2 and suitable for treating pneumothorax
ATE82504T1 (de) Herrichtung und verwendung eines physiologisch aktiven polypeptids zur aids-therapie.
JPS6423899A (en) Novel physiologically active polypeptide