CY2010007I1 - Προσδιορισμος in vivo δια την δοκιμασιαν της φαινοτυπικης σταθepοτητος - Google Patents

Προσδιορισμος in vivo δια την δοκιμασιαν της φαινοτυπικης σταθepοτητος

Info

Publication number
CY2010007I1
CY2010007I1 CY2010007C CY2010007C CY2010007I1 CY 2010007 I1 CY2010007 I1 CY 2010007I1 CY 2010007 C CY2010007 C CY 2010007C CY 2010007 C CY2010007 C CY 2010007C CY 2010007 I1 CY2010007 I1 CY 2010007I1
Authority
CY
Cyprus
Prior art keywords
vivo assay
phenotypic stability
test
test phenotypic
stability
Prior art date
Application number
CY2010007C
Other languages
English (en)
Other versions
CY2010007I2 (el
Original Assignee
Tigenix N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tigenix N.V. filed Critical Tigenix N.V.
Publication of CY2010007I2 publication Critical patent/CY2010007I2/el
Publication of CY2010007I1 publication Critical patent/CY2010007I1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0006Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CY2010007C 1999-10-06 2010-03-31 Προσδιορισμος in vivo δια την δοκιμασιαν της φαινοτυπικης σταθepοτητος CY2010007I1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99203273 1999-10-06
PCT/BE2000/000118 WO2001024833A2 (en) 1999-10-06 2000-10-06 In vivo assay for testing the phenotypic stability
EP00967443A EP1218037B1 (en) 1999-10-06 2000-10-06 In vivo assay for testing the phenotypic stability

Publications (2)

Publication Number Publication Date
CY2010007I2 CY2010007I2 (el) 2010-07-28
CY2010007I1 true CY2010007I1 (el) 2010-07-28

Family

ID=8240723

Family Applications (1)

Application Number Title Priority Date Filing Date
CY2010007C CY2010007I1 (el) 1999-10-06 2010-03-31 Προσδιορισμος in vivo δια την δοκιμασιαν της φαινοτυπικης σταθepοτητος

Country Status (12)

Country Link
US (2) US7479367B1 (el)
EP (2) EP1498146A3 (el)
AT (1) ATE285797T1 (el)
AU (1) AU7764200A (el)
CA (1) CA2397610C (el)
CY (1) CY2010007I1 (el)
DE (3) DE122010000021I1 (el)
DK (1) DK1218037T3 (el)
ES (2) ES2234673T3 (el)
LU (1) LU91672I2 (el)
PT (1) PT1218037E (el)
WO (1) WO2001024833A2 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2234673T3 (es) * 1999-10-06 2005-07-01 Tigenix N.V. Prueba in vivo para verificar la estabilidad fenotipica.
US7482114B2 (en) 1999-10-06 2009-01-27 Tigenix N.V. In vivo assay and molecular markers for testing the phenotypic stability of cell populations, and selected cell populations for autologous transplantation
AU2001266915A1 (en) 2000-06-14 2001-12-24 Case Western Reserve University Probes for chondrogenesis
AU2003254298A1 (en) * 2002-08-02 2004-02-23 Stratatech Corporation Species specific dna detection
CN101432419A (zh) 2006-03-20 2009-05-13 泰根尼克斯股份有限公司 保持、改善和恢复软骨细胞的软骨表型的方法
ES2452825T3 (es) 2006-11-24 2014-04-02 Tigenix N.V. Genes marcadores para su uso en la identificación de estabilidad fenotípica de condrocitos y en el cribado de factores que influyen en la producción de cartílago
CN101215565B (zh) * 2008-01-11 2011-04-27 华中农业大学 一种作为猪标记辅助选择的与免疫性状相关的分子标记的克隆及应用
GB0902793D0 (en) 2009-02-20 2009-04-08 Univ Gent GDF15 as molecular tool to monitor and enhance phenotypic stability of articular chondrocytes
EP3872168A1 (en) * 2020-02-28 2021-09-01 Cline Scientific AB Chondrocyte differentiation
US11505611B2 (en) 2020-08-21 2022-11-22 Genzyme Corporation FGFR3 antibodies and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837258A (en) * 1991-08-30 1998-11-17 University Of South Florida Induction of tissue, bone or cartilage formation using connective tissue growth factor
US5723331A (en) * 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
US5902785A (en) * 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
EP1342476A3 (en) 1995-06-12 2003-09-17 Yeda Research And Development Co. Ltd. FGFR3 as a marker for mesenchymal skeletal progenitor cells and use of cytotoxic conjugates comprising an FGFR3 binding agent for the treatment of cartilagineous bony tumours
AU742342B2 (en) 1997-05-21 2001-12-20 Clontech Laboratories, Inc. Nucleic acid arrays
AU7984498A (en) 1997-06-25 1999-01-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Serum-free cell growth medium
ES2234673T3 (es) * 1999-10-06 2005-07-01 Tigenix N.V. Prueba in vivo para verificar la estabilidad fenotipica.
DE20023640U1 (de) 1999-10-06 2005-06-23 Tigenix N.V. Isolierung von Vorläuferzellen und deren Verwendung zum Wiederaufbau von Bindegewebe
US7482114B2 (en) 1999-10-06 2009-01-27 Tigenix N.V. In vivo assay and molecular markers for testing the phenotypic stability of cell populations, and selected cell populations for autologous transplantation

Also Published As

Publication number Publication date
ES2488240T1 (es) 2014-08-26
EP1218037B1 (en) 2004-12-29
CA2397610A1 (en) 2001-04-12
US7479367B1 (en) 2009-01-20
LU91672I2 (fr) 2010-06-02
DE60017159T2 (de) 2006-05-04
US20090162328A1 (en) 2009-06-25
US9089598B2 (en) 2015-07-28
WO2001024833A2 (en) 2001-04-12
DK1218037T3 (da) 2005-04-25
ES2234673T3 (es) 2005-07-01
CY2010007I2 (el) 2010-07-28
DE122010000021I1 (de) 2012-09-06
DE20023659U1 (de) 2005-07-07
DE60017159D1 (de) 2005-02-03
ATE285797T1 (de) 2005-01-15
EP1498146A3 (en) 2007-01-24
PT1218037E (pt) 2005-05-31
EP1498146A2 (en) 2005-01-19
CA2397610C (en) 2012-07-03
WO2001024833A3 (en) 2001-12-20
EP1218037A2 (en) 2002-07-03
AU7764200A (en) 2001-05-10

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