CY1125352T1 - Κρυσταλλικες ενωσεις - Google Patents
Κρυσταλλικες ενωσειςInfo
- Publication number
- CY1125352T1 CY1125352T1 CY20221100470T CY221100470T CY1125352T1 CY 1125352 T1 CY1125352 T1 CY 1125352T1 CY 20221100470 T CY20221100470 T CY 20221100470T CY 221100470 T CY221100470 T CY 221100470T CY 1125352 T1 CY1125352 T1 CY 1125352T1
- Authority
- CY
- Cyprus
- Prior art keywords
- crystalline compounds
- naphthalen
- azabicyclo
- compositions
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/16—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
- C07C211/17—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562181174P | 2015-06-17 | 2015-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1125352T1 true CY1125352T1 (el) | 2025-05-09 |
Family
ID=57546597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20221100470T CY1125352T1 (el) | 2015-06-17 | 2022-07-11 | Κρυσταλλικες ενωσεις |
Country Status (25)
| Country | Link |
|---|---|
| US (6) | US9708261B2 (enExample) |
| EP (3) | EP4049997A1 (enExample) |
| JP (5) | JP6896651B2 (enExample) |
| KR (1) | KR102593783B1 (enExample) |
| CN (3) | CN117466800A (enExample) |
| AU (2) | AU2016279075C1 (enExample) |
| CA (2) | CA3200692A1 (enExample) |
| CY (1) | CY1125352T1 (enExample) |
| DK (1) | DK3597189T3 (enExample) |
| ES (1) | ES2922158T3 (enExample) |
| HK (1) | HK1247125A1 (enExample) |
| HR (1) | HRP20220829T1 (enExample) |
| HU (1) | HUE059348T2 (enExample) |
| LT (1) | LT3597189T (enExample) |
| MX (2) | MX387591B (enExample) |
| MY (1) | MY194868A (enExample) |
| NZ (2) | NZ739044A (enExample) |
| PH (1) | PH12017502324A1 (enExample) |
| PL (1) | PL3597189T3 (enExample) |
| PT (1) | PT3597189T (enExample) |
| SA (1) | SA517390552B1 (enExample) |
| SG (1) | SG10201911417PA (enExample) |
| SI (1) | SI3597189T1 (enExample) |
| TW (1) | TWI751998B (enExample) |
| WO (1) | WO2016205762A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200801825B (en) | 2005-07-27 | 2009-12-30 | Dov Pharmaceutical Inc | Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: Preparation and use to treat neuropsychiatric disorders |
| US20140206740A1 (en) | 2011-07-30 | 2014-07-24 | Neurovance, Inc. | Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters |
| EP3080080A4 (en) * | 2013-12-09 | 2017-08-16 | Neurovance, Inc. | Novel compositions |
| ES2922158T3 (es) | 2015-06-17 | 2022-09-09 | Otsuka America Pharmaceutical Inc | Compuestos cristalinos |
| US11149004B2 (en) | 2017-12-11 | 2021-10-19 | Crystal Pharmaceutical (Suzhou) Co., Ltd. | Crystalline form of EB-1020, processes for preparation and use thereof |
| CN114555557A (zh) * | 2019-10-16 | 2022-05-27 | 大塚制药株式会社 | 森塔纳法啶的制备方法 |
| US12698260B2 (en) * | 2021-05-31 | 2026-08-04 | Assia Chemical Industries Ltd. | Solid state form of centanafadine HCL and process for preparation thereof |
| US12502358B1 (en) | 2024-08-13 | 2025-12-23 | Innovate Therapeutics Llc | Centanafadine multiphasic controlled-release pharmaceutical formulation |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2005117630A (ru) | 2002-11-08 | 2006-01-20 | Дов Фармасьютикал, Инк. (Us) | Полиморфы гидрохлорида бицифадина |
| EP1740593B1 (en) | 2004-04-19 | 2016-04-06 | KRKA, tovarna zdravil, d.d., Novo mesto | Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form i |
| US20070043100A1 (en) | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
| CA2619817A1 (en) | 2004-08-18 | 2006-03-02 | Dov Pharmaceutical, Inc. | Thermodynamically stable polymorph of an azabicyclohexane |
| US20070082939A1 (en) | 2005-07-26 | 2007-04-12 | Lippa Arnold S | Methods and compositions for the treatment of neuropathies and related disorders |
| ZA200801825B (en) | 2005-07-27 | 2009-12-30 | Dov Pharmaceutical Inc | Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: Preparation and use to treat neuropsychiatric disorders |
| US7919598B2 (en) | 2006-06-28 | 2011-04-05 | Bristol-Myers Squibb Company | Crystal structures of SGLT2 inhibitors and processes for preparing same |
| US20080058535A1 (en) * | 2006-07-25 | 2008-03-06 | Zhengming Chen | Methods and compositions for production, formulation and use of 1 aryl-3-azabicyclo[3.1.0]hexanes |
| US8576985B2 (en) | 2009-09-01 | 2013-11-05 | Aptuit (West Lafayette) Llc | Methods for indexing solid forms of compounds |
| JP5808818B2 (ja) | 2010-11-25 | 2015-11-10 | ラツィオファーム・ゲーエムベーハー | アファチニブの新規塩及び多形形態 |
| EP2819516B1 (en) * | 2011-07-30 | 2019-12-25 | Otsuka America Pharmaceutical, Inc. | Use of (1r,5s)-(+)-1-(naphthalen-2-yl)-3-azabicyclo{3.1.0}hexane in the treatment of conditions affected by monoamine neurotransmitters |
| US20140206740A1 (en) | 2011-07-30 | 2014-07-24 | Neurovance, Inc. | Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters |
| US20140228421A1 (en) | 2011-09-07 | 2014-08-14 | Anthony McKinney | Methods For Inhibiting Native And Promiscuous Uptake Of Monoamine Neurotransmitters |
| EP3080080A4 (en) | 2013-12-09 | 2017-08-16 | Neurovance, Inc. | Novel compositions |
| ES2922158T3 (es) | 2015-06-17 | 2022-09-09 | Otsuka America Pharmaceutical Inc | Compuestos cristalinos |
-
2016
- 2016-06-17 ES ES19196556T patent/ES2922158T3/es active Active
- 2016-06-17 CN CN202310843667.7A patent/CN117466800A/zh active Pending
- 2016-06-17 CN CN201680035027.1A patent/CN107921021A/zh active Pending
- 2016-06-17 EP EP22164478.4A patent/EP4049997A1/en active Pending
- 2016-06-17 HK HK18106861.3A patent/HK1247125A1/zh unknown
- 2016-06-17 PL PL19196556.5T patent/PL3597189T3/pl unknown
- 2016-06-17 CA CA3200692A patent/CA3200692A1/en active Pending
- 2016-06-17 MX MX2017016430A patent/MX387591B/es unknown
- 2016-06-17 MY MYPI2017704811A patent/MY194868A/en unknown
- 2016-06-17 EP EP19196556.5A patent/EP3597189B1/en active Active
- 2016-06-17 WO PCT/US2016/038256 patent/WO2016205762A1/en not_active Ceased
- 2016-06-17 DK DK19196556.5T patent/DK3597189T3/da active
- 2016-06-17 PT PT191965565T patent/PT3597189T/pt unknown
- 2016-06-17 HR HRP20220829TT patent/HRP20220829T1/hr unknown
- 2016-06-17 AU AU2016279075A patent/AU2016279075C1/en active Active
- 2016-06-17 EP EP16812592.0A patent/EP3310352A4/en not_active Ceased
- 2016-06-17 HU HUE19196556A patent/HUE059348T2/hu unknown
- 2016-06-17 JP JP2017565236A patent/JP6896651B2/ja active Active
- 2016-06-17 US US15/186,415 patent/US9708261B2/en active Active
- 2016-06-17 SI SI201631552T patent/SI3597189T1/sl unknown
- 2016-06-17 NZ NZ739044A patent/NZ739044A/en unknown
- 2016-06-17 CN CN202310848120.6A patent/CN117088802A/zh active Pending
- 2016-06-17 KR KR1020187001083A patent/KR102593783B1/ko active Active
- 2016-06-17 NZ NZ776973A patent/NZ776973A/en unknown
- 2016-06-17 SG SG10201911417PA patent/SG10201911417PA/en unknown
- 2016-06-17 LT LTEP19196556.5T patent/LT3597189T/lt unknown
- 2016-06-17 CA CA2989431A patent/CA2989431C/en active Active
- 2016-12-21 TW TW105142467A patent/TWI751998B/zh active
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2017
- 2017-06-01 US US15/611,580 patent/US9856217B2/en active Active
- 2017-11-21 US US15/820,241 patent/US10280141B2/en active Active
- 2017-12-14 SA SA517390552A patent/SA517390552B1/ar unknown
- 2017-12-15 PH PH12017502324A patent/PH12017502324A1/en unknown
- 2017-12-15 MX MX2020009949A patent/MX2020009949A/es unknown
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2019
- 2019-03-11 US US16/298,179 patent/US10800740B2/en active Active
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2020
- 2020-08-14 US US16/993,648 patent/US11299458B2/en active Active
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2021
- 2021-01-19 AU AU2021200314A patent/AU2021200314B2/en active Active
- 2021-06-09 JP JP2021096354A patent/JP7244575B2/ja active Active
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2022
- 2022-07-11 CY CY20221100470T patent/CY1125352T1/el unknown
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2023
- 2023-03-09 JP JP2023036730A patent/JP7583851B2/ja active Active
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2024
- 2024-11-01 JP JP2024192608A patent/JP2025022896A/ja active Pending
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2026
- 2026-01-12 US US19/446,625 patent/US20260138950A1/en active Pending
- 2026-02-24 JP JP2026027045A patent/JP2026083082A/ja active Pending
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