CY1124208T1 - Αλατα η συγκρυσταλλοι της 3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης - Google Patents

Αλατα η συγκρυσταλλοι της 3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης

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Publication number
CY1124208T1
CY1124208T1 CY20211100462T CY211100462T CY1124208T1 CY 1124208 T1 CY1124208 T1 CY 1124208T1 CY 20211100462 T CY20211100462 T CY 20211100462T CY 211100462 T CY211100462 T CY 211100462T CY 1124208 T1 CY1124208 T1 CY 1124208T1
Authority
CY
Cyprus
Prior art keywords
dimethylamino
phenol
propyl
ethyl
methyl
Prior art date
Application number
CY20211100462T
Other languages
English (en)
Inventor
Michael Gruss
Magda Kraszewski
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43302522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1124208(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of CY1124208T1 publication Critical patent/CY1124208T1/el

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    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract

Η εφεύρεση αφορά ένα άλας ή συγκρύσταλλο 3- (3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)- φαινόλης (συστατικό a) και τουλάχιστον ένα συστατικό οξέος (b1) ή τουλάχιστον ένα συστατικό οξέος (b2), όπου το άλας ή ο συνκρύσταλλος του συστατικού (a) και του συστατικού (b2) υπάρχει σε κρυσταλλική και/ή άμορφη μορφή, ένα φάρμακο που περιλαμβάνει το εν λόγω άλας ή συγκρύσταλλο όπως επίσης το εν λόγω άλας ή συγκρύσταλλος για χρήση στη θεραπεία του πόνου.
CY20211100462T 2010-07-23 2021-05-27 Αλατα η συγκρυσταλλοι της 3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης CY1124208T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP10007672 2010-07-23
EP17191453.4A EP3287447A1 (en) 2010-07-23 2011-07-22 Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
PCT/EP2011/003674 WO2012010316A1 (en) 2010-07-23 2011-07-22 Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
EP11743775.6A EP2595971A1 (en) 2010-07-23 2011-07-22 Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol

Publications (1)

Publication Number Publication Date
CY1124208T1 true CY1124208T1 (el) 2022-05-27

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CY20211100166T CY1123852T1 (el) 2010-07-23 2021-02-26 Αλατα ή συγκρυσταλλοι της 3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης
CY20211100462T CY1124208T1 (el) 2010-07-23 2021-05-27 Αλατα η συγκρυσταλλοι της 3-(3-διμεθυλαμινο-1-αιθυλο-2-μεθυλο-προπυλο)-φαινολης

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US (1) US9133142B2 (el)
EP (8) EP3656765B1 (el)
JP (4) JP5968884B2 (el)
KR (2) KR102146233B1 (el)
CN (4) CN106831456A (el)
AU (9) AU2011281923C1 (el)
CA (2) CA3078668A1 (el)
CY (2) CY1123852T1 (el)
DK (2) DK3656765T3 (el)
ES (2) ES2860676T3 (el)
HK (1) HK1250231A1 (el)
HR (2) HRP20210343T1 (el)
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PT (2) PT3656765T (el)
RS (2) RS61515B1 (el)
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WO (1) WO2012010316A1 (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10250083A1 (de) 2002-06-17 2003-12-24 Gruenenthal Gmbh Gegen Missbrauch gesicherte Darreichungsform
WO2012010316A1 (en) 2010-07-23 2012-01-26 Grünenthal GmbH Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
WO2013111161A2 (en) * 2012-01-10 2013-08-01 Msn Laboratories Limited Process for the preparation of 3-aryl-2-methyl-propanamine derivatives and polymorphs thereof
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