CY1122222T1 - Συνθεση βορονικων αλατων και χρησεις αυτων - Google Patents
Συνθεση βορονικων αλατων και χρησεις αυτωνInfo
- Publication number
- CY1122222T1 CY1122222T1 CY20191101140T CY191101140T CY1122222T1 CY 1122222 T1 CY1122222 T1 CY 1122222T1 CY 20191101140 T CY20191101140 T CY 20191101140T CY 191101140 T CY191101140 T CY 191101140T CY 1122222 T1 CY1122222 T1 CY 1122222T1
- Authority
- CY
- Cyprus
- Prior art keywords
- composition
- boron salts
- crystalline
- formulation
- synthesis
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical class OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
- A01N55/08—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing boron
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dentistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
Abstract
Στο παρόν αποκαλύπτονται βορονικά ενδιάμεσα στη σύνθεση αντιμικροβιακών ενώσεων και η χρήση και παρασκευή αυτών. Ορισμένες υλοποιήσεις αναφέρονται σε κρυσταλλικά παράγωγα βορονικού άλατος και στη χρήση αυτών στη σύνθεση θεραπευτικών ενώσεων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461988690P | 2014-05-05 | 2014-05-05 | |
PCT/US2015/028613 WO2015171430A1 (en) | 2014-05-05 | 2015-04-30 | Synthesis of boronate salts and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1122222T1 true CY1122222T1 (el) | 2020-11-25 |
Family
ID=54392864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20191101140T CY1122222T1 (el) | 2014-05-05 | 2019-11-01 | Συνθεση βορονικων αλατων και χρησεις αυτων |
Country Status (14)
Country | Link |
---|---|
US (2) | US10385074B2 (el) |
EP (3) | EP3140310B1 (el) |
CY (1) | CY1122222T1 (el) |
DK (1) | DK3140310T3 (el) |
ES (2) | ES2972939T3 (el) |
FI (1) | FI3604316T3 (el) |
HR (1) | HRP20191932T1 (el) |
HU (1) | HUE046836T2 (el) |
LT (2) | LT3140310T (el) |
PL (2) | PL3604316T3 (el) |
PT (1) | PT3140310T (el) |
RS (1) | RS59488B1 (el) |
SI (1) | SI3140310T1 (el) |
WO (1) | WO2015171430A1 (el) |
Families Citing this family (20)
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PT2603514T (pt) | 2010-08-10 | 2018-11-09 | Rempex Pharmaceuticals Inc | Derivados cíclicos de éster de ácido borónico e suas utilizações terapêuticas |
WO2014107535A1 (en) | 2013-01-04 | 2014-07-10 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
CN106459096B (zh) | 2014-05-19 | 2019-03-08 | 莱姆派克斯制药公司 | 硼酸衍生物及其治疗用途 |
WO2015191907A1 (en) | 2014-06-11 | 2015-12-17 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
US9511142B2 (en) | 2014-06-11 | 2016-12-06 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
MX2016016666A (es) | 2014-07-01 | 2017-08-08 | Rempex Pharmaceuticals Inc | Derivados de acido boronico y usos terapeuticos de los mismos. |
US10662205B2 (en) | 2014-11-18 | 2020-05-26 | Qpex Biopharma, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
WO2016100043A1 (en) | 2014-12-19 | 2016-06-23 | Rempex Pharmaceuticals, Inc. | Apparatus and continuous flow process for production of boronic acid derivatives |
WO2016149393A1 (en) | 2015-03-17 | 2016-09-22 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
EP3347008B1 (en) | 2015-09-11 | 2022-03-09 | Venatorx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
WO2017100537A1 (en) | 2015-12-10 | 2017-06-15 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
WO2018005662A1 (en) | 2016-06-30 | 2018-01-04 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
EP3494121B1 (en) | 2016-08-04 | 2021-10-06 | Venatorx Pharmaceuticals, Inc. | Boron-containing compounds |
JOP20190188A1 (ar) | 2017-02-01 | 2019-08-01 | Rempex Pharmaceuticals Inc | جهاز وعملية تدفق مستمرة لإنتاج مشتق حمض بورونيك |
EP3630782A4 (en) | 2017-05-26 | 2021-03-03 | Venatorx Pharmaceuticals, Inc. | PENICILLIN BINDING PROTEIN INHIBITORS |
US11267826B2 (en) | 2017-05-26 | 2022-03-08 | VenatoRx Pharmaceuticals, Inc. | Penicillin-binding protein inhibitors |
BR112020007138B1 (pt) | 2017-10-11 | 2023-03-21 | Qpex Biopharma, Inc | Derivados de ácido borônico, métodos de síntese, composição farmacêutica e uso dos mesmos |
CA3080763A1 (en) * | 2017-11-01 | 2019-05-09 | Melinta Therapeutics, Inc. | Synthesis of boronate ester derivatives and uses thereof |
EP3781576B1 (en) | 2018-04-20 | 2024-06-12 | Qpex Biopharma, Inc. | Boronic acid derivatives and therapeutic uses thereof |
CN111039965B (zh) * | 2018-10-12 | 2020-12-01 | 新发药业有限公司 | 一种法硼巴坦的简便制备方法 |
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-
2015
- 2015-04-30 ES ES19186092T patent/ES2972939T3/es active Active
- 2015-04-30 EP EP15788682.1A patent/EP3140310B1/en active Active
- 2015-04-30 US US15/305,954 patent/US10385074B2/en active Active
- 2015-04-30 DK DK15788682.1T patent/DK3140310T3/da active
- 2015-04-30 PL PL19186092.3T patent/PL3604316T3/pl unknown
- 2015-04-30 SI SI201530973T patent/SI3140310T1/sl unknown
- 2015-04-30 PL PL15788682T patent/PL3140310T3/pl unknown
- 2015-04-30 PT PT157886821T patent/PT3140310T/pt unknown
- 2015-04-30 LT LT15788682T patent/LT3140310T/lt unknown
- 2015-04-30 ES ES15788682T patent/ES2750805T3/es active Active
- 2015-04-30 EP EP19186092.3A patent/EP3604316B1/en active Active
- 2015-04-30 EP EP23214076.4A patent/EP4356736A3/en active Pending
- 2015-04-30 WO PCT/US2015/028613 patent/WO2015171430A1/en active Application Filing
- 2015-04-30 FI FIEP19186092.3T patent/FI3604316T3/fi active
- 2015-04-30 HU HUE15788682A patent/HUE046836T2/hu unknown
- 2015-04-30 LT LTEP19186092.3T patent/LT3604316T/lt unknown
- 2015-04-30 RS RS20191368A patent/RS59488B1/sr unknown
-
2019
- 2019-08-02 US US16/530,625 patent/US10669292B2/en active Active
- 2019-10-23 HR HRP20191932TT patent/HRP20191932T1/hr unknown
- 2019-11-01 CY CY20191101140T patent/CY1122222T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
LT3604316T (lt) | 2024-02-26 |
DK3140310T3 (da) | 2019-10-21 |
EP3140310B1 (en) | 2019-08-07 |
US10669292B2 (en) | 2020-06-02 |
PL3140310T3 (pl) | 2020-01-31 |
HUE046836T2 (hu) | 2020-03-30 |
PT3140310T (pt) | 2019-11-18 |
US20200031851A1 (en) | 2020-01-30 |
US20170057979A1 (en) | 2017-03-02 |
PL3604316T3 (pl) | 2024-04-29 |
EP4356736A3 (en) | 2024-08-07 |
LT3140310T (lt) | 2019-11-25 |
WO2015171430A1 (en) | 2015-11-12 |
US10385074B2 (en) | 2019-08-20 |
ES2972939T3 (es) | 2024-06-17 |
FI3604316T3 (fi) | 2024-02-29 |
EP4356736A2 (en) | 2024-04-24 |
EP3604316B1 (en) | 2023-12-06 |
EP3140310A1 (en) | 2017-03-15 |
SI3140310T1 (sl) | 2020-01-31 |
ES2750805T3 (es) | 2020-03-27 |
EP3140310A4 (en) | 2017-12-13 |
EP3604316A1 (en) | 2020-02-05 |
HRP20191932T1 (hr) | 2020-01-24 |
RS59488B1 (sr) | 2019-12-31 |
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