CY1116837T1 - Αλληλουχιες κυκλοϊου σχετικου με την νοσο απισχνασης του χοιριδιου (map) - Google Patents
Αλληλουχιες κυκλοϊου σχετικου με την νοσο απισχνασης του χοιριδιου (map)Info
- Publication number
- CY1116837T1 CY1116837T1 CY20151100916T CY151100916T CY1116837T1 CY 1116837 T1 CY1116837 T1 CY 1116837T1 CY 20151100916 T CY20151100916 T CY 20151100916T CY 151100916 T CY151100916 T CY 151100916T CY 1116837 T1 CY1116837 T1 CY 1116837T1
- Authority
- CY
- Cyprus
- Prior art keywords
- map
- polypeptides
- circulating
- prevention
- treatment
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 208000036142 Viral infection Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 230000009385 viral infection Effects 0.000 abstract 2
- 241001190084 Cyclovirus Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002463 transducing effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A61P37/02—Immunomodulators
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
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- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
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- C12N2750/10011—Circoviridae
- C12N2750/10051—Methods of production or purification of viral material
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- C12N2750/10011—Circoviridae
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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Abstract
Η εφεύρεση έχει για αντικείμενο τη γονιδιωματική αλληλουχία και νουκλεοτιδικές αλληλουχίες που κωδικοποιούν πολυπεπτίδια του κυκλοϊού MAP, όπως τα δομικά και μη δομικά πολυπεπτίδια του εν λόγω κυκλοϊού, καθώς επίσης και φορείς που συμπεριλαμβάνουν τις εν λόγω αλληλουχίες και κύτταρα ή ζώα που μετασχηματίζονται με αυτούς τους φορείς. Η εφεύρεση αφορά επίσης μεθόδους ανίχνευσης αυτών των νουκλεϊκών οξέων ή πολυπεπτιδίων και κιτ διάγνωσης της μόλυνσης από έναν κυκλοϊό MAP. Η εφεύρεση στοχεύει επίσης σε μια μέθοδο επιλογής ενώσεων ικανών να διαμορφώνουν την ιική μόλυνση. Η εφεύρεση συμπεριλαμβάνει τέλος φαρμακευτικές συνθέσεις, κυρίως εμβόλια, για την πρόληψη ή/και τη θεραπεία ιικών μολύνσεων από κυκλοϊό MAP, καθώς επίσης τη χρήση φορέα σύμφωνα με την εφεύρεση για την πρόληψη ή/και την αγωγή ασθενειών με γονιδιακή θεραπεία.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9715396A FR2772047B1 (fr) | 1997-12-05 | 1997-12-05 | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
EP10184626.9A EP2330188B1 (fr) | 1997-12-05 | 1998-12-04 | Séquences de circovirus associé à la maladie de l'amaigrissement du porcelet (MAP) |
Publications (1)
Publication Number | Publication Date |
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CY1116837T1 true CY1116837T1 (el) | 2017-03-15 |
Family
ID=9514225
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
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CY20141100270T CY1115405T1 (el) | 1997-12-05 | 2014-04-11 | Αλληλουχιες κυκλοϊου που συνδyαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY20141100318T CY1115424T1 (el) | 1997-12-05 | 2014-05-05 | Αλληλουχιες κυκλοϊου που συνδυαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY2014035C CY2014035I1 (el) | 1997-12-05 | 2014-08-19 | Αλληλουχιες κυκλοϊου που συνδυαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY2014036C CY2014036I2 (el) | 1997-12-05 | 2014-08-19 | Αλληλουχιες κυκλοϊου που συνδαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY20151100872T CY1116761T1 (el) | 1997-12-05 | 2015-09-30 | Αλληλουχιες κυκλοϊου σχετικου με την νοσο απισχνασης του χοιριδιου (map) |
CY20151100916T CY1116837T1 (el) | 1997-12-05 | 2015-10-09 | Αλληλουχιες κυκλοϊου σχετικου με την νοσο απισχνασης του χοιριδιου (map) |
Family Applications Before (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20141100270T CY1115405T1 (el) | 1997-12-05 | 2014-04-11 | Αλληλουχιες κυκλοϊου που συνδyαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY20141100318T CY1115424T1 (el) | 1997-12-05 | 2014-05-05 | Αλληλουχιες κυκλοϊου που συνδυαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY2014035C CY2014035I1 (el) | 1997-12-05 | 2014-08-19 | Αλληλουχιες κυκλοϊου που συνδυαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY2014036C CY2014036I2 (el) | 1997-12-05 | 2014-08-19 | Αλληλουχιες κυκλοϊου που συνδαζονται με την ασθενεια της καχεξιας του χοιριδιου (map) |
CY20151100872T CY1116761T1 (el) | 1997-12-05 | 2015-09-30 | Αλληλουχιες κυκλοϊου σχετικου με την νοσο απισχνασης του χοιριδιου (map) |
Country Status (15)
Country | Link |
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US (43) | US6703023B1 (el) |
EP (6) | EP1992696B1 (el) |
AT (1) | ATE412664T1 (el) |
AU (1) | AU1491699A (el) |
BE (2) | BE2014C049I2 (el) |
CY (6) | CY1115405T1 (el) |
DE (1) | DE69840174D1 (el) |
DK (5) | DK2330188T3 (el) |
ES (5) | ES2548146T3 (el) |
FR (3) | FR2772047B1 (el) |
HK (5) | HK1125676A1 (el) |
LU (2) | LU92523I2 (el) |
NL (2) | NL300686I2 (el) |
PT (5) | PT2330188E (el) |
WO (1) | WO1999029871A2 (el) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7211379B2 (en) | 1997-10-03 | 2007-05-01 | Merial Sas | Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2 |
US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
US6391314B1 (en) | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
US7192594B2 (en) | 1997-10-03 | 2007-03-20 | Merial Limited | Postweaning multisystemic wasting syndrome and porcine circovirus from pigs |
UA78180C2 (uk) * | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
AU2002302120B2 (en) * | 1997-10-03 | 2006-01-19 | Merial | Porcine circoviruses, vaccines and diagnostic reagents |
AU2003248395B2 (en) * | 1997-10-03 | 2006-03-16 | Merial | Porcine CircoViruses, vaccines and diagnostic reagents |
FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
PT2363488E (pt) * | 1997-12-11 | 2015-01-13 | Univ Belfast | Síndrome multi-sistémica do definhamento pós-desmame de porcos |
EP1816200B1 (en) * | 1997-12-11 | 2016-03-09 | Merial | Postweaning multisystemic wasting syndrome virus for pigs |
EP1064024A4 (en) * | 1998-03-13 | 2005-04-06 | Univ Georgia Res Found | VACCINES AGAINST CIRCOVIRUS INFECTIONS |
US6943152B1 (en) * | 1999-06-10 | 2005-09-13 | Merial | DNA vaccine-PCV |
ES2170622B1 (es) * | 1999-12-03 | 2004-05-16 | Consejo Superior De Investigaciones Cientificas | Clones y vectores infectivos derivados de coronavirus y sus aplicaciones. |
WO2001061024A2 (en) | 2000-02-16 | 2001-08-23 | Large Scale Biology Corporation | Rolling circle replicon expression vectors |
ES2324466T3 (es) | 2001-03-27 | 2009-08-07 | University Of Saskatchewan | Metodos para cultivar circovirus. |
US7279166B2 (en) | 2001-12-12 | 2007-10-09 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
US7276353B2 (en) * | 2001-12-12 | 2007-10-02 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
US7833707B2 (en) | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
AU2011253941B2 (en) * | 2004-12-30 | 2015-01-29 | Boehringer Ingelheim Animal Health USA Inc. | PCV2 immunogenic compositions and methods of producing such compositions |
UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
PT2281829E (pt) | 2004-12-30 | 2015-02-18 | Boehringer Ingelheim Vetmed | Composições imunogénicas de pcv2 para utilização num método de prevenção de infecção de pcv2 |
US7700285B1 (en) | 2005-12-29 | 2010-04-20 | Boehringer Ingelheim Vetmedica, Inc. | PCV2 immunogenic compositions and methods of producing such compositions |
ITBO20050123A1 (it) | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
TW200643171A (en) * | 2005-06-07 | 2006-12-16 | Temasek Life Sciences Lab Ltd | Porcine circovirus type 2 vaccines |
CN101277717A (zh) * | 2005-09-09 | 2008-10-01 | 英特威国际有限公司 | Pcv-2疫苗 |
CN109125721A (zh) | 2005-12-29 | 2019-01-04 | 贝林格尔.英格海姆维特梅迪卡有限公司 | Pcv2免疫原性组合物用于减轻猪临床症状的用途 |
RU2488407C2 (ru) | 2005-12-29 | 2013-07-27 | Берингер Ингельхайм Ветмедика, Инк. | Поливалентные иммуногенные композиции pcv2 и способы получения таких композиций |
WO2008064299A2 (en) * | 2006-11-22 | 2008-05-29 | Boehringer Ingelheim Vetmedica, Inc. | Methods of reducing porcine circovirus-associated disease outbreaks |
US20100129397A1 (en) * | 2006-12-11 | 2010-05-27 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
PT2094872T (pt) * | 2006-12-15 | 2017-04-27 | Boehringer Ingelheim Vetmedica Inc | Tratamento de porcos seropositivos para o anticorpo anti-pcv2 com antigénio de pcv2 |
EP1941903A1 (en) * | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
EP1958644A1 (en) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
US8518696B2 (en) * | 2007-05-11 | 2013-08-27 | Temasek Life Sciences Laboratory Limited | Production of homogeneous cell line highly permissive to porcine circovirus type 2 (PCV2) infection |
US7829274B2 (en) | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
EP2225367A1 (en) * | 2007-12-21 | 2010-09-08 | Wyeth LLC | Methods and compositions for immunizing pigs against porcine circovirus |
CA2710558A1 (en) * | 2007-12-31 | 2009-07-16 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 orf2 virus like particle with foreign amino acid insertion |
CA2712006A1 (en) * | 2008-01-23 | 2009-10-15 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions |
US20110033495A1 (en) * | 2008-02-15 | 2011-02-10 | Boehringer Ingelheim Vetmedica, Inc. | Methods and compositions for reducing the impact of enteric diseases |
AU2009303845B2 (en) * | 2008-10-16 | 2013-09-12 | Zoetis Llc | Torque teno virus (TTV) isolates and compositions |
WO2011046634A1 (en) * | 2009-10-16 | 2011-04-21 | Pfizer, Inc. | Infectious clones of torque teno virus |
US20100150959A1 (en) * | 2008-12-15 | 2010-06-17 | Vectogen Pty Ltd. | PCV 2-Based Methods and Compositions for the Treatment of Pigs |
AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
CA2775093A1 (en) | 2009-10-02 | 2011-04-07 | Pioneer Hi-Bred International, Inc. | Down-regulation of acc synthase for improved plant performance |
US8846388B2 (en) | 2009-10-16 | 2014-09-30 | Zoetis Llc | Infectious clones of torque teno virus |
CA2777159A1 (en) * | 2009-10-22 | 2011-04-28 | Universitat Leipzig | Detection of a circovirus in calves suffering from bovine neonatal pancytopenia |
EP2528931A4 (en) * | 2010-01-25 | 2013-12-04 | Blood Systems Inc | CYCLOVIRUS AND USE METHOD THEREFOR |
KR20110090711A (ko) * | 2010-02-04 | 2011-08-10 | 녹십자수의약품(주) | 신규한 돼지 써코바이러스 타입 2 및 그의 용도 |
TWI508974B (zh) | 2010-12-22 | 2015-11-21 | Sbc Virbac Ltd | 豬第二型環狀病毒(Porcine Circovirus Type 2)、含彼之免疫組合物、檢測套組及其應用 |
CN103502269A (zh) | 2011-04-29 | 2014-01-08 | 先锋国际良种公司 | 下调同源域-亮氨酸拉链i类同源盒基因以改进植物性能 |
HUP1100470A2 (en) | 2011-08-30 | 2013-03-28 | Mezoegazdasagi Biotechnologiai Kutatokoezpont | Nanoparticle-based veterinary vaccine |
EP2564869A1 (en) | 2011-09-02 | 2013-03-06 | Ceva Sante Animale | Synthetic capsid proteins and uses thereof |
UA113192C2 (xx) | 2011-12-06 | 2016-12-26 | Імуногенна композиція проти цирковірусу свиней типу 2 (pcv2) | |
US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
UA114503C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
EP2961766B1 (en) * | 2013-03-01 | 2019-04-10 | Boehringer Ingelheim Vetmedica, Inc. | Quantification of vaccine compositions |
KR102217387B1 (ko) * | 2013-03-11 | 2021-02-19 | 주식회사 중앙백신연구소 | 재조합 효모 전세포(yeast whole cell)을 이용한 돼지 써코바이러스(PCV2) 서브유닛 백신과 그의 제조 방법 |
EP2789346A1 (en) | 2013-04-11 | 2014-10-15 | CEVA Santé Animale SA | Fusion polypeptides and vaccines |
EP2994162B1 (en) | 2013-05-08 | 2021-04-07 | Pharmgate Biologics Inc. | Vaccine for pcv2 and mycoplasma |
KR20160046879A (ko) | 2013-09-25 | 2016-04-29 | 조에티스 서비시즈 엘엘씨 | Pcv2b 분지형 백신 조성물 및 사용 방법 |
KR102409183B1 (ko) | 2013-10-02 | 2022-06-15 | 베링거 인겔하임 애니멀 헬스 유에스에이 인크. | Pcv2 orf2 단백질 변이체 및 이로 이루어진 바이러스 유사 입자 |
EP3034609A1 (en) | 2014-12-19 | 2016-06-22 | Ceva Sante Animale | Recombinant swinepox virus and vaccines |
EP3254692A1 (en) | 2016-06-10 | 2017-12-13 | Ceva Sante Animale | Multivalent recombinant spv |
WO2019032830A1 (en) | 2017-08-09 | 2019-02-14 | Dreamwell, Ltd. | ADJUSTABLE SUPPORT STRUCTURE |
US20200390878A1 (en) | 2017-12-08 | 2020-12-17 | Ceva Sante Animale | Recombinant swinepox virus and vaccines |
MX2020010018A (es) | 2018-03-26 | 2020-10-14 | Boehringer Ingelheim Animal Health Usa Inc | Metodo para producir una composicion inmunogenica. |
MX2020013484A (es) | 2018-06-11 | 2021-05-27 | Ceva Sante Animale | Vacunacion contra circovirus porcinos. |
EP4225940A1 (en) * | 2020-10-06 | 2023-08-16 | Materials and Machines Corporation of America | Method for detection of rna or dna from biological samples |
WO2023192936A2 (en) * | 2022-03-30 | 2023-10-05 | Fred Hutchinson Cancer Center | Systems and methods to produce b cells that express selected antibodies and gene products |
CN114736310B (zh) * | 2022-06-10 | 2022-10-28 | 北京华夏兴洋生物科技有限公司 | 产生圆环病毒2型病毒样颗粒的蛋白质及生物材料与应用 |
Family Cites Families (112)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US69750A (en) * | 1867-10-15 | Henry bean | ||
US69233A (en) * | 1867-09-24 | Joseph r | ||
FR2422956A1 (fr) | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
FR2464269B1 (fr) | 1979-08-30 | 1986-04-18 | Anvar | Sequence nucleotidique codant l'antigene de surface du virus de l'hepatite b, procede permettant son obtention et antigene obtenu |
FR2518755B1 (fr) | 1981-12-23 | 1986-04-11 | Pasteur Institut | Sonde contenant un acide nucleique modifie et reconnaissable par des anticorps specifiques et utilisation de cette sonde pour detecter et caracteriser une sequence d'adn homologue |
US5833975A (en) | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
US4745051A (en) | 1983-05-27 | 1988-05-17 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
US5550289A (en) | 1985-01-07 | 1996-08-27 | Syntex (U.S.A.) Inc. | N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N-tetrasubstituted ammonium lipids and uses therefor |
US4946787A (en) | 1985-01-07 | 1990-08-07 | Syntex (U.S.A.) Inc. | N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
US5106733A (en) | 1987-06-25 | 1992-04-21 | Immunex Corporation | Bovine granulocyte-macrophage colony stimulating factor |
SU1538305A1 (ru) | 1987-07-21 | 1994-12-15 | Всесоюзный государственный научно-контрольный институт ветеринарных препаратов Госагропрома СССР | Ассоциированная вакцина против лептоспироза и парвовирусной инфекции свиней |
US5069901A (en) | 1988-02-03 | 1991-12-03 | Jones Elaine V | Preparation of a recombinant subunit vaccine against pseudorabies infection |
WO1990007935A1 (en) | 1989-01-23 | 1990-07-26 | Auspharm International Ltd. | Vaccine composition |
US5811103A (en) | 1989-03-19 | 1998-09-22 | Akzo Nobel N.V. | Hog cholera virus vaccine and diagnostic |
CA2489769A1 (en) | 1989-03-21 | 1990-10-04 | Philip L. Felgner | Expression of exogenous polynucleotide sequences in a vertebrate |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
EP0597852B2 (en) | 1990-05-29 | 2005-08-10 | Wyeth Holdings Corporation | Swine pneumonia vaccine and method for the preparation thereof |
US5565205A (en) | 1990-08-16 | 1996-10-15 | Solvay Animal Health, Inc. | Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof |
WO1992005255A1 (en) | 1990-09-13 | 1992-04-02 | Commonwealth Scientific And Industrial Research Organisation | Ovine cytokine genes |
GB9023111D0 (en) | 1990-10-24 | 1990-12-05 | Wellcome Found | Expression system |
ES2150419T3 (es) | 1990-11-01 | 2000-12-01 | Univ Iowa State Res Found Inc | Procedimiento de atenuacion bacteriana y vacuna. |
WO1992015672A1 (en) | 1991-03-07 | 1992-09-17 | Virogenetics Corporation | Genetically engineered vaccine strain |
ES2026827A6 (es) | 1991-03-26 | 1992-05-01 | Ercros Sa | Procedimiento para la produccion de una vacuna subunidad contra el parvovirus porcino. |
US5580557A (en) | 1991-10-09 | 1996-12-03 | Iowa State University Research Foundation, Inc. | Live, avirulent salmonella choleraesuis vaccine used for inducing an immune response in animals |
US6033904A (en) | 1992-01-13 | 2000-03-07 | Syntro Corporation | Recombinant swinepox virus |
US5382425A (en) | 1992-01-13 | 1995-01-17 | Syntro Corporation | Recombinant swinepox virus |
US5338543A (en) | 1992-02-27 | 1994-08-16 | Ambico, Inc. | Thimerosal inactivated mycoplasma hyopneumoniae vaccine |
AU4662393A (en) | 1992-07-08 | 1994-01-31 | Schering Corporation | Use of gm-csf as a vaccine adjuvant |
JP3149116B2 (ja) * | 1992-10-28 | 2001-03-26 | 信越化学工業株式会社 | ヒトパルボウイルスのエピトープ関連ペプチド |
DE69333610D1 (de) * | 1992-11-09 | 2004-10-07 | Zonagen Inc | Methoden für die immunoempfängnisverhütung |
DK0683816T3 (da) | 1993-02-08 | 2001-01-08 | Bayer Ag | Fremgangsmåde til dyrkning af porcinreproduktions- og respirationssygdom-virus og dets anvendelse i vacciner |
IL108915A0 (en) | 1993-03-18 | 1994-06-24 | Merck & Co Inc | Polynucleotide vaccine against influenza virus |
EP0698245A1 (en) | 1993-05-14 | 1996-02-28 | Mds Health Group Limited | Electronic worksheet system for microbiology testing and reporting |
EP0702516A4 (en) | 1993-06-01 | 1998-04-22 | Life Technologies Inc | GENETIC IMMUNIZATION WITH CATIONIC LIPIDS |
WO1994029469A2 (en) | 1993-06-07 | 1994-12-22 | Vical Incorporated | Plasmids suitable for gene therapy |
US6015686A (en) | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
FR2711670B1 (fr) | 1993-10-22 | 1996-01-12 | Pasteur Institut | Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite. |
GB2285766B (en) | 1994-01-21 | 1997-07-23 | Ecc Int Ltd | Ceramic casting composition |
KR0121105B1 (ko) * | 1994-02-04 | 1997-11-10 | 문정환 | 선입선출메모리 버스장치 |
WO1995024929A2 (en) | 1994-03-15 | 1995-09-21 | Brown University Research Foundation | Polymeric gene delivery system |
DK0758397T3 (da) | 1994-04-29 | 2005-10-10 | Baxter Healthcare Sa | Rekombinante poxvira med fremmede polynucleotider i essentielle regioner |
ES2429401T3 (es) | 1994-05-10 | 2013-11-14 | Boehringer Ingelheim Vetmedica, Inc. | Vacuna viva modificada contra el BRSV, mejorada |
GB2289279B (en) | 1994-05-13 | 1998-09-16 | Iberica Cyanamid | Diagnostic kits and vaccines containing recombinant PRRSV proteins |
US5719131A (en) | 1994-12-09 | 1998-02-17 | Genzyme Corporation | Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules |
US5840306A (en) * | 1995-03-22 | 1998-11-24 | Merck & Co., Inc. | DNA encoding human papillomavirus type 18 |
US6043232A (en) | 1997-07-23 | 2000-03-28 | Nitromed, Inc. | Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs |
WO1996034109A1 (en) | 1995-04-25 | 1996-10-31 | Vical Incorporated | Single-vial formulations of dna/lipid complexes |
US5681658A (en) * | 1995-05-30 | 1997-10-28 | Aluminum Company Of America | Gelation-resistant alumina |
US5885823A (en) | 1995-06-05 | 1999-03-23 | Nobl Laboratories, Inc. | Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
US5820869A (en) | 1995-06-07 | 1998-10-13 | American Home Products Corporation | Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection |
US6019980A (en) | 1995-06-07 | 2000-02-01 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
US5705385A (en) | 1995-06-07 | 1998-01-06 | Inex Pharmaceuticals Corporation | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer |
WO1996040931A1 (en) | 1995-06-07 | 1996-12-19 | Aesculaap B.V. | Neutralizing conformational epitopes of chicken anemia virus |
US5795872A (en) | 1995-09-19 | 1998-08-18 | Pharmadigm, Inc. | DNA construct for immunization |
FR2751224B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
ATE199022T1 (de) | 1996-10-09 | 2001-02-15 | Akzo Nobel Nv | Europäische vakzinstämme des fortplanzungs- atmungs-syndromsvirus des sweins (prrsv) |
AU1987197A (en) | 1997-03-10 | 1998-09-29 | Heather Lynn Davis | Gene delivery to mucosal epithelium for immunization or therapeutic purpose |
US6004777A (en) | 1997-03-12 | 1999-12-21 | Virogenetics Corporation | Vectors having enhanced expression, and methods of making and uses thereof |
US5990091A (en) | 1997-03-12 | 1999-11-23 | Virogenetics Corporation | Vectors having enhanced expression, and methods of making and uses thereof |
US20030215445A1 (en) * | 1997-05-23 | 2003-11-20 | Ginette Serrero | Methods and compositions for inhibiting the growth of hematopoietic malignant cells |
FR2769322B1 (fr) | 1997-10-03 | 2002-03-08 | Merial Sas | Nouveaux circovirus porcins, vaccins et reactifs de diagnostic |
UA78180C2 (uk) * | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
FR2769321B1 (fr) | 1997-10-03 | 2001-10-26 | Merial Sas | Nouveaux circovirus porcins, vaccins et reactifs de diagnostics |
US7192594B2 (en) * | 1997-10-03 | 2007-03-20 | Merial Limited | Postweaning multisystemic wasting syndrome and porcine circovirus from pigs |
US6143334A (en) * | 1997-10-03 | 2000-11-07 | Sargento Foods Inc. | Pasta filata method for manufacturing Swiss-type cheeses |
US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
FR2781159B1 (fr) | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
US6391314B1 (en) * | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
US7211379B2 (en) * | 1997-10-03 | 2007-05-01 | Merial Sas | Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2 |
US6165493A (en) | 1997-10-22 | 2000-12-26 | New York Blood Center, Inc. | "Methods and compositions for decreasing the frequency of HIV, herpesvirus and sexually transmitted bacterial infections" |
US20040062775A1 (en) | 1997-12-05 | 2004-04-01 | Agence Francaise De Securite Sanitaire Des Aliments | Circovirus sequences associated with piglet weight loss disease (PWD) |
FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
PT2363488E (pt) * | 1997-12-11 | 2015-01-13 | Univ Belfast | Síndrome multi-sistémica do definhamento pós-desmame de porcos |
EP1064024A4 (en) * | 1998-03-13 | 2005-04-06 | Univ Georgia Res Found | VACCINES AGAINST CIRCOVIRUS INFECTIONS |
US6294176B1 (en) | 1998-07-10 | 2001-09-25 | Schering-Plough Veterinary Corp. | Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species |
AU1131200A (en) | 1998-10-23 | 2000-05-15 | Heska Corporation | Cationic lipid-mediated enhancement of nucleic acid immunization of cats |
US6143333A (en) | 1998-11-13 | 2000-11-07 | Purina Mills, Inc. | Method of preparing a packaged fish attractant block |
FR2789695B1 (fr) | 1999-02-11 | 2003-03-07 | Merial Sas | Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs |
US6497883B1 (en) | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
US6943152B1 (en) | 1999-06-10 | 2005-09-13 | Merial | DNA vaccine-PCV |
US6179461B1 (en) | 1999-09-03 | 2001-01-30 | Davis-Standard Corporation | Extruder screw |
US6139179A (en) | 1999-09-03 | 2000-10-31 | Davis-Standard Corporation | Extruder screw having multi-channeled barrier section |
WO2001017556A1 (fr) | 1999-09-07 | 2001-03-15 | Shionogi & Co., Ltd. | Préparations vaccinales administrables par les muqueuses |
GB9921147D0 (en) | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
GB9921146D0 (en) | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
WO2001034609A1 (de) * | 1999-11-10 | 2001-05-17 | Optische Werke G. Rodenstock | Heterocyclisch annellierte indenochromenderivate |
US6366601B1 (en) * | 1999-11-17 | 2002-04-02 | Motorola, Inc. | Variable rate spread spectrum communication method and apparatus |
US7233407B1 (en) * | 2000-02-02 | 2007-06-19 | Xerox Corporation | Document production system for capturing web page content |
JP3363419B2 (ja) * | 1999-12-24 | 2003-01-08 | 住友ゴム工業株式会社 | 重荷重用ラジアルタイヤ |
CA2410229A1 (en) | 2000-06-15 | 2001-12-20 | Purdue Research Foundation | Vaccine for congenital tremors in pigs |
JP4768106B2 (ja) | 2000-07-31 | 2011-09-07 | スリーエム イノベイティブ プロパティズ カンパニー | 接着剤組成物及び熱剥離容易な接着構造 |
DE10044648A1 (de) | 2000-09-08 | 2002-03-21 | Aventis Behring Gmbh | Verfahren zur Vermehrung oder zur Entfernung von Cirocoviren aus biologischem Material |
DE10044646A1 (de) | 2000-09-08 | 2002-04-04 | Horsch Maschinen Gmbh | Spritzgestängeführung |
DE10051562A1 (de) * | 2000-10-18 | 2002-04-25 | Emitec Emissionstechnologie | Beheizbarer Wabenkörper mit zwei verschiedenen Beschichtungen |
US6572081B2 (en) * | 2000-12-27 | 2003-06-03 | Nkf Kabel B.V. | Installation of guide tubes in a protective duct |
ES2324466T3 (es) * | 2001-03-27 | 2009-08-07 | University Of Saskatchewan | Metodos para cultivar circovirus. |
AUPR567401A0 (en) | 2001-06-14 | 2001-07-12 | University Of Melbourne, The | Circovirus vaccines |
US7276353B2 (en) | 2001-12-12 | 2007-10-02 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
US7279166B2 (en) | 2001-12-12 | 2007-10-09 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
US20030215455A1 (en) | 2002-05-14 | 2003-11-20 | Bailey Reynolds | Vaccine stabilizer and method of use |
ATE397299T1 (de) * | 2002-11-28 | 2008-06-15 | Research In Motion Ltd | Mehrfachband-antenne mit patch- und schlitzstrukturen |
US7288529B2 (en) * | 2003-04-24 | 2007-10-30 | New York University | ALK protein tyrosine kinase, cells and methods embodying and using same |
KR101131845B1 (ko) | 2003-07-25 | 2012-03-30 | 베링거잉겔하임베트메디카인코퍼레이티드 | 유럽 기원의 로소니아 인트라셀룰라리스, 및 이의 백신,진단제 및 사용 방법 |
US20050279889A1 (en) | 2004-06-08 | 2005-12-22 | Safe Flight Instrument Corporation | Variable wing spacecraft |
US7833707B2 (en) | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
CN101189027A (zh) | 2005-01-13 | 2008-05-28 | 贝林格尔·英格海姆维特梅迪卡有限公司 | 改良的prrs疫苗 |
SI1869471T1 (sl) | 2005-04-13 | 2016-09-30 | Merial, Inc. | Postopek za izdelavo prašičjega cirkovirusa |
CN109125721A (zh) | 2005-12-29 | 2019-01-04 | 贝林格尔.英格海姆维特梅迪卡有限公司 | Pcv2免疫原性组合物用于减轻猪临床症状的用途 |
US8377070B2 (en) * | 2007-05-17 | 2013-02-19 | Michael T. Gauthier | Compressor distractor tool |
US8214576B2 (en) | 2009-03-03 | 2012-07-03 | Vmware, Inc. | Zero copy transport for target based storage virtual appliances |
-
1997
- 1997-12-05 FR FR9715396A patent/FR2772047B1/fr not_active Expired - Lifetime
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1998
- 1998-12-04 EP EP08154913.1A patent/EP1992696B1/fr not_active Expired - Lifetime
- 1998-12-04 EP EP10184556.8A patent/EP2316925B1/fr not_active Expired - Lifetime
- 1998-12-04 AU AU14916/99A patent/AU1491699A/en not_active Abandoned
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- 1998-12-04 EP EP10184626.9A patent/EP2330188B1/fr not_active Expired - Lifetime
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- 1998-12-04 DK DK08154912.3T patent/DK2000535T3/da active
- 1998-12-04 DK DK98958957.7T patent/DK1036180T4/da active
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2000
- 2000-02-28 US US09/514,245 patent/US6703023B1/en not_active Expired - Lifetime
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2003
- 2003-04-09 US US10/409,613 patent/US20040076635A1/en not_active Abandoned
- 2003-05-21 US US10/442,180 patent/US20040091502A1/en not_active Abandoned
- 2003-08-08 US US10/637,011 patent/US7223594B2/en not_active Expired - Lifetime
- 2003-11-21 US US10/718,266 patent/US7148015B2/en not_active Expired - Lifetime
- 2003-11-21 US US10/718,264 patent/US7179472B2/en not_active Expired - Lifetime
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2004
- 2004-02-11 US US10/775,337 patent/US20050008651A1/en not_active Abandoned
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2005
- 2005-07-08 US US11/176,667 patent/US7244433B2/en not_active Expired - Lifetime
- 2005-10-31 US US11/262,514 patent/US7261898B2/en not_active Expired - Lifetime
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- 2006-07-17 US US11/487,589 patent/US7407803B2/en not_active Expired - Fee Related
- 2006-07-19 US US11/488,926 patent/US7405075B2/en not_active Expired - Fee Related
- 2006-07-19 US US11/488,885 patent/US7297537B2/en not_active Expired - Fee Related
- 2006-10-27 US US11/588,237 patent/US7722883B2/en not_active Expired - Fee Related
- 2006-10-27 US US11/588,302 patent/US7390494B2/en not_active Expired - Fee Related
- 2006-10-27 US US11/588,306 patent/US7425444B2/en not_active Expired - Fee Related
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- 2006-10-27 US US11/588,305 patent/US7323330B2/en not_active Expired - Fee Related
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2007
- 2007-11-01 US US11/979,296 patent/US7740866B2/en not_active Expired - Fee Related
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- 2008-07-03 US US12/216,410 patent/US7758865B2/en not_active Expired - Fee Related
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- 2009-05-19 HK HK09104574.7A patent/HK1125676A1/xx not_active IP Right Cessation
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