CY1116117T1 - Σταθεροποιημενα πολυπεπτιδια αυξητικου παραγοντα ινσουλινομορφου της ινσουλινης - Google Patents

Σταθεροποιημενα πολυπεπτιδια αυξητικου παραγοντα ινσουλινομορφου της ινσουλινης

Info

Publication number
CY1116117T1
CY1116117T1 CY20151100260T CY151100260T CY1116117T1 CY 1116117 T1 CY1116117 T1 CY 1116117T1 CY 20151100260 T CY20151100260 T CY 20151100260T CY 151100260 T CY151100260 T CY 151100260T CY 1116117 T1 CY1116117 T1 CY 1116117T1
Authority
CY
Cyprus
Prior art keywords
insulin
informational
stabilized
polypeptides
growth
Prior art date
Application number
CY20151100260T
Other languages
English (en)
Inventor
David Jonathan Glass
Mara Fornaro
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38801859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1116117(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1116117T1 publication Critical patent/CY1116117T1/el

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

Η εφεύρεση αναφέρεται στα σταθεροποιημένα πολυπεπτίδια που έχουν μια αλληλουχία IGF-1 ή IGF-2 και μια αλληλουχία πεπτιδίου-Ε, όπου η φυσική, φυσιολογική διάσπαση του πεπτιδίου-Ε από τον IGF εμποδίζεται.
CY20151100260T 2006-06-09 2015-03-13 Σταθεροποιημενα πολυπεπτιδια αυξητικου παραγοντα ινσουλινομορφου της ινσουλινης CY1116117T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81234906P 2006-06-09 2006-06-09
US86224406P 2006-10-20 2006-10-20
US89718707P 2007-01-24 2007-01-24
EP07798148.8A EP2032155B1 (en) 2006-06-09 2007-06-06 Stabilized insulin-like growth factor polypeptides

Publications (1)

Publication Number Publication Date
CY1116117T1 true CY1116117T1 (el) 2017-02-08

Family

ID=38801859

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100260T CY1116117T1 (el) 2006-06-09 2015-03-13 Σταθεροποιημενα πολυπεπτιδια αυξητικου παραγοντα ινσουλινομορφου της ινσουλινης

Country Status (33)

Country Link
US (4) US20100173839A1 (el)
EP (2) EP2032155B1 (el)
JP (2) JP2009539805A (el)
KR (1) KR101459789B1 (el)
AR (1) AR061242A1 (el)
AU (2) AU2007255419A1 (el)
BR (2) BRPI0712052A2 (el)
CA (2) CA2653781A1 (el)
CL (1) CL2007001614A1 (el)
CR (2) CR10432A (el)
CY (1) CY1116117T1 (el)
DK (2) DK2032155T3 (el)
EC (1) ECSP088949A (el)
ES (1) ES2529261T3 (el)
GT (1) GT200800273A (el)
HK (1) HK1126429A1 (el)
HR (1) HRP20150326T1 (el)
IL (1) IL195156A (el)
JO (1) JO2968B1 (el)
MA (1) MA30503B1 (el)
MX (2) MX2008015657A (el)
MY (1) MY147856A (el)
NO (2) NO20085183L (el)
NZ (2) NZ572548A (el)
PE (1) PE20080715A1 (el)
PL (1) PL2032155T3 (el)
PT (1) PT2032155E (el)
RU (1) RU2477287C2 (el)
SI (1) SI2032155T1 (el)
TN (1) TNSN08509A1 (el)
TW (1) TWI427084B (el)
UA (1) UA97953C2 (el)
WO (2) WO2007146689A2 (el)

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WO2010088502A2 (en) * 2009-01-30 2010-08-05 The Regents Of The University Of California Insulin-like growth factor signaling and integrin
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Also Published As

Publication number Publication date
HRP20150326T1 (hr) 2015-04-24
CA2653781A1 (en) 2007-12-13
IL195156A (en) 2014-07-31
EP2032155B1 (en) 2014-12-24
CR20160115A (es) 2016-06-14
BRPI0712147A2 (pt) 2012-02-22
ECSP088949A (es) 2009-01-30
DK200900016A (da) 2009-01-06
RU2008151511A (ru) 2010-07-20
CA2654944A1 (en) 2007-12-21
NO20085183L (no) 2009-03-09
NO20085184L (no) 2009-03-03
PT2032155E (pt) 2015-04-07
WO2007146689A9 (en) 2010-12-16
KR20090027197A (ko) 2009-03-16
JP2009539805A (ja) 2009-11-19
BRPI0712052A2 (pt) 2012-01-10
JP2009539383A (ja) 2009-11-19
TWI427084B (zh) 2014-02-21
US20170066808A9 (en) 2017-03-09
MX2008015726A (es) 2008-12-19
TNSN08509A1 (en) 2010-04-14
PL2032155T3 (pl) 2015-05-29
ES2529261T3 (es) 2015-02-18
NZ572548A (en) 2011-06-30
WO2007141309A3 (en) 2008-05-29
IL195156A0 (en) 2011-08-01
RU2477287C2 (ru) 2013-03-10
MA30503B1 (fr) 2009-06-01
MY147856A (en) 2013-01-31
TW200835698A (en) 2008-09-01
AR061242A1 (es) 2008-08-13
WO2007146689A3 (en) 2008-04-10
MX2008015657A (es) 2009-02-04
KR101459789B1 (ko) 2014-11-07
US20100173839A1 (en) 2010-07-08
JO2968B1 (en) 2016-03-15
WO2007146689A2 (en) 2007-12-21
AU2007257936B2 (en) 2011-05-26
WO2007141309A2 (en) 2007-12-13
CA2654944C (en) 2017-01-03
SI2032155T1 (sl) 2015-04-30
PE20080715A1 (es) 2008-07-25
US8343918B2 (en) 2013-01-01
US20130059779A1 (en) 2013-03-07
US20140235538A1 (en) 2014-08-21
JP5290966B2 (ja) 2013-09-18
CL2007001614A1 (es) 2008-08-08
NZ572708A (en) 2011-11-25
AU2007257936A1 (en) 2007-12-21
EP2032154A2 (en) 2009-03-11
GT200800273A (es) 2009-09-16
AU2007255419A1 (en) 2007-12-13
HK1126429A1 (en) 2009-09-04
US8722621B2 (en) 2014-05-13
US20100234290A1 (en) 2010-09-16
DK2032155T3 (en) 2015-03-02
UA97953C2 (uk) 2012-04-10
EP2032155A2 (en) 2009-03-11
CR10432A (es) 2009-01-15

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