CY1115450T1 - Ενωση παραγωγου κυκλοεξανιου - Google Patents

Ενωση παραγωγου κυκλοεξανιου

Info

Publication number
CY1115450T1
CY1115450T1 CY20141100614T CY141100614T CY1115450T1 CY 1115450 T1 CY1115450 T1 CY 1115450T1 CY 20141100614 T CY20141100614 T CY 20141100614T CY 141100614 T CY141100614 T CY 141100614T CY 1115450 T1 CY1115450 T1 CY 1115450T1
Authority
CY
Cyprus
Prior art keywords
alkyl group
optionally substituted
group
hydrogen atom
alkyl
Prior art date
Application number
CY20141100614T
Other languages
Greek (el)
English (en)
Inventor
Narihiro Toda
Rieko Takano
Takeshi Shida
Takahiro Katagiri
Mitsuhiro Iwamoto
Shinji Ashida
Mami Yamazaki
Original Assignee
Daiichi Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Company, Limited filed Critical Daiichi Sankyo Company, Limited
Publication of CY1115450T1 publication Critical patent/CY1115450T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C07D213/643—2-Phenoxypyridines; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CY20141100614T 2010-09-27 2014-08-06 Ενωση παραγωγου κυκλοεξανιου CY1115450T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010215403 2010-09-27
EP11828999.0A EP2623492B1 (en) 2010-09-27 2011-09-26 Cyclohexane derivative compound

Publications (1)

Publication Number Publication Date
CY1115450T1 true CY1115450T1 (el) 2017-01-04

Family

ID=45892891

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20141100614T CY1115450T1 (el) 2010-09-27 2014-08-06 Ενωση παραγωγου κυκλοεξανιου

Country Status (29)

Country Link
US (3) US8710060B2 (enExample)
EP (1) EP2623492B1 (enExample)
JP (1) JP5753179B2 (enExample)
KR (1) KR20130109124A (enExample)
CN (1) CN103108866B (enExample)
AU (1) AU2011309212B2 (enExample)
BR (1) BR112013007145A2 (enExample)
CA (1) CA2812898C (enExample)
CO (1) CO6690804A2 (enExample)
CY (1) CY1115450T1 (enExample)
DK (1) DK2623492T3 (enExample)
ES (1) ES2478518T3 (enExample)
HR (1) HRP20140720T1 (enExample)
IL (1) IL225440A (enExample)
IN (1) IN2013MN00506A (enExample)
MX (1) MX2013003219A (enExample)
MY (1) MY157542A (enExample)
NZ (1) NZ609596A (enExample)
PH (1) PH12013500583A1 (enExample)
PL (1) PL2623492T3 (enExample)
PT (1) PT2623492E (enExample)
RS (1) RS53447B (enExample)
RU (1) RU2013119603A (enExample)
SG (1) SG188415A1 (enExample)
SI (1) SI2623492T1 (enExample)
SM (1) SMT201400109B (enExample)
TW (1) TWI501953B (enExample)
WO (1) WO2012043445A1 (enExample)
ZA (1) ZA201301652B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103108866B (zh) * 2010-09-27 2015-09-09 第一三共株式会社 环己烷衍生物化合物
US10352962B2 (en) 2016-12-29 2019-07-16 BioMech Sensor LLC Systems and methods for real-time data quantification, acquisition, analysis and feedback
US11318350B2 (en) 2016-12-29 2022-05-03 BioMech Sensor LLC Systems and methods for real-time data quantification, acquisition, analysis, and feedback
US9773330B1 (en) 2016-12-29 2017-09-26 BioMech Sensor LLC Systems and methods for real-time data quantification, acquisition, analysis, and feedback
US10973439B2 (en) 2016-12-29 2021-04-13 BioMech Sensor LLC Systems and methods for real-time data quantification, acquisition, analysis, and feedback

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511980B2 (en) * 2000-05-05 2003-01-28 Ortho Mcneil Pharmaceutical, Inc. Substituted diamine derivatives useful as motilin antagonists
US7262195B2 (en) 2003-09-17 2007-08-28 Bristol-Myers Squibb Company Compounds useful as motilin agonists and method
GB0611907D0 (en) * 2006-06-15 2006-07-26 Glaxo Group Ltd Compounds
GB0515381D0 (en) * 2005-07-26 2005-08-31 Glaxo Group Ltd Compounds
GB0612844D0 (en) * 2006-06-28 2006-08-09 Glaxo Group Ltd Compounds
PL2041093T3 (pl) 2006-06-28 2010-09-30 Glaxo Group Ltd Pochodne piperazynylowe użyteczne w leczeniu zaburzeń, którym pośredniczy receptor GPR38
GB0723317D0 (en) * 2007-11-28 2008-01-09 Glaxo Group Ltd Compounds
CN103108866B (zh) * 2010-09-27 2015-09-09 第一三共株式会社 环己烷衍生物化合物

Also Published As

Publication number Publication date
US9051255B2 (en) 2015-06-09
DK2623492T3 (da) 2014-08-11
NZ609596A (en) 2013-12-20
HRP20140720T1 (hr) 2014-08-29
SG188415A1 (en) 2013-04-30
CN103108866B (zh) 2015-09-09
PT2623492E (pt) 2014-08-29
IL225440A (en) 2015-11-30
TWI501953B (zh) 2015-10-01
US20140221391A1 (en) 2014-08-07
SI2623492T1 (sl) 2014-09-30
AU2011309212A1 (en) 2013-03-21
CA2812898A1 (en) 2012-04-05
MY157542A (en) 2016-06-15
EP2623492A1 (en) 2013-08-07
IN2013MN00506A (enExample) 2015-05-29
JP5753179B2 (ja) 2015-07-22
AU2011309212B2 (en) 2014-06-19
PL2623492T3 (pl) 2014-09-30
BR112013007145A2 (pt) 2016-06-14
RU2013119603A (ru) 2014-11-10
HK1185081A1 (en) 2014-02-07
US20140221392A1 (en) 2014-08-07
US8710060B2 (en) 2014-04-29
PH12013500583A1 (en) 2013-05-20
IL225440A0 (en) 2013-06-27
TW201217342A (en) 2012-05-01
EP2623492B1 (en) 2014-05-14
KR20130109124A (ko) 2013-10-07
CN103108866A (zh) 2013-05-15
EP2623492A4 (en) 2013-09-25
CA2812898C (en) 2015-11-17
WO2012043445A1 (ja) 2012-04-05
US20130289048A1 (en) 2013-10-31
JPWO2012043445A1 (ja) 2014-02-06
ZA201301652B (en) 2014-04-30
SMT201400109B (it) 2014-09-08
RS53447B (sr) 2014-12-31
CO6690804A2 (es) 2013-06-17
ES2478518T3 (es) 2014-07-22
MX2013003219A (es) 2013-06-18

Similar Documents

Publication Publication Date Title
CY1119220T1 (el) Μονοκυκλικο παραγωγο πυριδινης
CY1121231T1 (el) Παραγωγο τετραϋδροϊμιδαζο[1,5-d][1,4]οξαζεπινης
JO3131B1 (ar) مركبات كيميائية
CO6321168A2 (es) Nuevos derivados de 2-amidotiadiazol
EA201001683A1 (ru) Производные фенил- или пиридинилзамещенных индазолов
AR072227A1 (es) Derivados de triazinona sustituidos
ATE555113T1 (de) Spirozyklische derivate als histondeacetylase- inhibitoren
ATE542813T1 (de) 6-substituierte 2- heterocyclylaminopyrazinverbindungen als chk-1- inhibitoren
BR112014006660A2 (pt) novos derivados de dihidroquinolina-2-ona bicíclicos
CY1114520T1 (el) Παραγωγο ινδολιζινης και χρηση αυτου για ιατρικους σκοπους
UA114611C2 (uk) Пестицидні композиції і способи, що їх стосуються
ECSP13012858A (es) Derivados de piperidina puenteada
UA105786C2 (uk) Адитивні солі амінів, що містять гідроксильні і/або карбоксильні групи, з похідними амінонікотинової кислоти як інгібітори dhodh
AR047817A1 (es) Derivados de aril- y heteroarilpiperidincarboxilatos, su preparacion y su aplicacion en terapeutica
CY1121677T1 (el) Ενωσεις διμεθυλοβενζοϊκου οξεος
BR112015015275A2 (pt) composto heterocíclico substituído por halogênio
CY1121984T1 (el) Μη-ορμονικοι στεροειδεις ρυθμιστες toy nf-kb για θεραπεια ασθενειας
AR093659A1 (es) Derivados ciclicos de nucleosidos y usos de los mismos
AR072229A1 (es) Derivados de n- oxido pirazina sustituidos
CO6821935A2 (es) Derivados novedosos de cefalosporinas y cmposiciones farmacéuticas de estos
CY1119296T1 (el) Ενωση δικαρβοξυλικου οξεος
CY1114400T1 (el) Θεραπευτικες εφαρμογες των παραγωγων κιναζολινεδιονης
MX2018014944A (es) Tratamiento para la enfermedad de parkinson.
BR112015028871A2 (pt) novos compostos de 3,4-dihidro-2h-isoquinolina-1-ona e 2,3-dihidro-isoindol-1-ona
BR112013007145A2 (pt) composto ou sal farmacologicamente aceitável, medicamento, e, uso do composto ou sal farmacologicamente aceitável