KR20130109124A - 시클로헥산 유도체 화합물 - Google Patents
시클로헥산 유도체 화합물Info
- Publication number
- KR20130109124A KR20130109124A KR1020137007448A KR20137007448A KR20130109124A KR 20130109124 A KR20130109124 A KR 20130109124A KR 1020137007448 A KR1020137007448 A KR 1020137007448A KR 20137007448 A KR20137007448 A KR 20137007448A KR 20130109124 A KR20130109124 A KR 20130109124A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- methyl
- substituted
- phenyl
- trans
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CCC(C*(CC(CCC1)CCCC1[*@](C(C)=CC)C(C1CC(C)CC(*C)CC1)=O)CC1*)*1IC Chemical compound CCC(C*(CC(CCC1)CCCC1[*@](C(C)=CC)C(C1CC(C)CC(*C)CC1)=O)CC1*)*1IC 0.000 description 4
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C07D213/643—2-Phenoxypyridines; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010215403 | 2010-09-27 | ||
| JPJP-P-2010-215403 | 2010-09-27 | ||
| PCT/JP2011/071830 WO2012043445A1 (ja) | 2010-09-27 | 2011-09-26 | シクロヘキサン誘導体化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20130109124A true KR20130109124A (ko) | 2013-10-07 |
Family
ID=45892891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137007448A Withdrawn KR20130109124A (ko) | 2010-09-27 | 2011-09-26 | 시클로헥산 유도체 화합물 |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US8710060B2 (enExample) |
| EP (1) | EP2623492B1 (enExample) |
| JP (1) | JP5753179B2 (enExample) |
| KR (1) | KR20130109124A (enExample) |
| CN (1) | CN103108866B (enExample) |
| AU (1) | AU2011309212B2 (enExample) |
| BR (1) | BR112013007145A2 (enExample) |
| CA (1) | CA2812898C (enExample) |
| CO (1) | CO6690804A2 (enExample) |
| CY (1) | CY1115450T1 (enExample) |
| DK (1) | DK2623492T3 (enExample) |
| ES (1) | ES2478518T3 (enExample) |
| HR (1) | HRP20140720T1 (enExample) |
| IL (1) | IL225440A (enExample) |
| IN (1) | IN2013MN00506A (enExample) |
| MX (1) | MX2013003219A (enExample) |
| MY (1) | MY157542A (enExample) |
| NZ (1) | NZ609596A (enExample) |
| PH (1) | PH12013500583A1 (enExample) |
| PL (1) | PL2623492T3 (enExample) |
| PT (1) | PT2623492E (enExample) |
| RS (1) | RS53447B (enExample) |
| RU (1) | RU2013119603A (enExample) |
| SG (1) | SG188415A1 (enExample) |
| SI (1) | SI2623492T1 (enExample) |
| SM (1) | SMT201400109B (enExample) |
| TW (1) | TWI501953B (enExample) |
| WO (1) | WO2012043445A1 (enExample) |
| ZA (1) | ZA201301652B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103108866B (zh) * | 2010-09-27 | 2015-09-09 | 第一三共株式会社 | 环己烷衍生物化合物 |
| US10352962B2 (en) | 2016-12-29 | 2019-07-16 | BioMech Sensor LLC | Systems and methods for real-time data quantification, acquisition, analysis and feedback |
| US11318350B2 (en) | 2016-12-29 | 2022-05-03 | BioMech Sensor LLC | Systems and methods for real-time data quantification, acquisition, analysis, and feedback |
| US9773330B1 (en) | 2016-12-29 | 2017-09-26 | BioMech Sensor LLC | Systems and methods for real-time data quantification, acquisition, analysis, and feedback |
| US10973439B2 (en) | 2016-12-29 | 2021-04-13 | BioMech Sensor LLC | Systems and methods for real-time data quantification, acquisition, analysis, and feedback |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511980B2 (en) * | 2000-05-05 | 2003-01-28 | Ortho Mcneil Pharmaceutical, Inc. | Substituted diamine derivatives useful as motilin antagonists |
| US7262195B2 (en) | 2003-09-17 | 2007-08-28 | Bristol-Myers Squibb Company | Compounds useful as motilin agonists and method |
| GB0611907D0 (en) * | 2006-06-15 | 2006-07-26 | Glaxo Group Ltd | Compounds |
| GB0515381D0 (en) * | 2005-07-26 | 2005-08-31 | Glaxo Group Ltd | Compounds |
| GB0612844D0 (en) * | 2006-06-28 | 2006-08-09 | Glaxo Group Ltd | Compounds |
| PL2041093T3 (pl) | 2006-06-28 | 2010-09-30 | Glaxo Group Ltd | Pochodne piperazynylowe użyteczne w leczeniu zaburzeń, którym pośredniczy receptor GPR38 |
| GB0723317D0 (en) * | 2007-11-28 | 2008-01-09 | Glaxo Group Ltd | Compounds |
| CN103108866B (zh) * | 2010-09-27 | 2015-09-09 | 第一三共株式会社 | 环己烷衍生物化合物 |
-
2011
- 2011-09-26 CN CN201180046082.8A patent/CN103108866B/zh not_active Expired - Fee Related
- 2011-09-26 RS RS20140388A patent/RS53447B/sr unknown
- 2011-09-26 RU RU2013119603/04A patent/RU2013119603A/ru not_active Application Discontinuation
- 2011-09-26 IN IN506MUN2013 patent/IN2013MN00506A/en unknown
- 2011-09-26 MX MX2013003219A patent/MX2013003219A/es active IP Right Grant
- 2011-09-26 JP JP2012536427A patent/JP5753179B2/ja not_active Expired - Fee Related
- 2011-09-26 MY MYPI2013000841A patent/MY157542A/en unknown
- 2011-09-26 KR KR1020137007448A patent/KR20130109124A/ko not_active Withdrawn
- 2011-09-26 PT PT118289990T patent/PT2623492E/pt unknown
- 2011-09-26 BR BR112013007145A patent/BR112013007145A2/pt not_active IP Right Cessation
- 2011-09-26 DK DK11828999.0T patent/DK2623492T3/da active
- 2011-09-26 PL PL11828999T patent/PL2623492T3/pl unknown
- 2011-09-26 PH PH1/2013/500583A patent/PH12013500583A1/en unknown
- 2011-09-26 SI SI201130160T patent/SI2623492T1/sl unknown
- 2011-09-26 HR HRP20140720AT patent/HRP20140720T1/hr unknown
- 2011-09-26 EP EP11828999.0A patent/EP2623492B1/en active Active
- 2011-09-26 ES ES11828999.0T patent/ES2478518T3/es active Active
- 2011-09-26 WO PCT/JP2011/071830 patent/WO2012043445A1/ja not_active Ceased
- 2011-09-26 NZ NZ609596A patent/NZ609596A/en not_active IP Right Cessation
- 2011-09-26 CA CA2812898A patent/CA2812898C/en not_active Expired - Fee Related
- 2011-09-26 TW TW100134525A patent/TWI501953B/zh not_active IP Right Cessation
- 2011-09-26 SG SG2013016464A patent/SG188415A1/en unknown
- 2011-09-26 AU AU2011309212A patent/AU2011309212B2/en not_active Ceased
-
2013
- 2013-03-04 ZA ZA2013/01652A patent/ZA201301652B/en unknown
- 2013-03-21 IL IL225440A patent/IL225440A/en not_active IP Right Cessation
- 2013-03-26 US US13/850,981 patent/US8710060B2/en not_active Expired - Fee Related
- 2013-04-19 CO CO13101069A patent/CO6690804A2/es active IP Right Grant
- 2013-12-27 US US14/142,479 patent/US9051255B2/en not_active Expired - Fee Related
- 2013-12-27 US US14/142,486 patent/US20140221392A1/en not_active Abandoned
-
2014
- 2014-08-06 SM SM201400109T patent/SMT201400109B/xx unknown
- 2014-08-06 CY CY20141100614T patent/CY1115450T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20130325 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |