CY1112741T1 - Αλας φουμαρικου οξεος και 3-[2-(διμεθυλαμινο)μεθυλο-(κυκλοεξ-1-υλο)]-φαινολη και οι κρυσταλλικες μορφες της - Google Patents
Αλας φουμαρικου οξεος και 3-[2-(διμεθυλαμινο)μεθυλο-(κυκλοεξ-1-υλο)]-φαινολη και οι κρυσταλλικες μορφες τηςInfo
- Publication number
- CY1112741T1 CY1112741T1 CY20121100333T CY121100333T CY1112741T1 CY 1112741 T1 CY1112741 T1 CY 1112741T1 CY 20121100333 T CY20121100333 T CY 20121100333T CY 121100333 T CY121100333 T CY 121100333T CY 1112741 T1 CY1112741 T1 CY 1112741T1
- Authority
- CY
- Cyprus
- Prior art keywords
- cyclohex
- methyl
- salum
- fenol
- dimethylamine
- Prior art date
Links
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 title 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title 2
- 239000013078 crystal Substances 0.000 title 1
- -1 cyclohex-1-yl Chemical group 0.000 title 1
- 239000001530 fumaric acid Substances 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title 1
- DYUBYVPYECCFFH-WLHGVMLRSA-N (e)-but-2-enedioic acid;3-[2-[(dimethylamino)methyl]cyclohexyl]phenol Chemical compound OC(=O)\C=C\C(O)=O.CN(C)CC1CCCCC1C1=CC=CC(O)=C1 DYUBYVPYECCFFH-WLHGVMLRSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005034973A DE102005034973A1 (de) | 2005-07-22 | 2005-07-22 | Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen |
| EP06776326A EP1907350B1 (de) | 2005-07-22 | 2006-07-20 | Salz von fumarsäure und 3- (2-dimethylamino) methyl- ( cyclohex-1-yl) ) phenol un dessen kristalline formen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1112741T1 true CY1112741T1 (el) | 2016-02-10 |
Family
ID=37101332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100333T CY1112741T1 (el) | 2005-07-22 | 2012-04-04 | Αλας φουμαρικου οξεος και 3-[2-(διμεθυλαμινο)μεθυλο-(κυκλοεξ-1-υλο)]-φαινολη και οι κρυσταλλικες μορφες της |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1907350B1 (https=) |
| JP (1) | JP5205260B2 (https=) |
| AR (1) | AR057673A1 (https=) |
| AT (1) | ATE540919T1 (https=) |
| CA (1) | CA2615741A1 (https=) |
| CY (1) | CY1112741T1 (https=) |
| DE (1) | DE102005034973A1 (https=) |
| DK (1) | DK1907350T3 (https=) |
| ES (1) | ES2380799T3 (https=) |
| PE (1) | PE20070375A1 (https=) |
| PL (1) | PL1907350T3 (https=) |
| PT (1) | PT1907350E (https=) |
| SI (1) | SI1907350T1 (https=) |
| WO (1) | WO2007009793A1 (https=) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19525137C2 (de) * | 1995-07-11 | 2003-02-27 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe |
| DE10000312A1 (de) * | 2000-01-05 | 2001-07-12 | Gruenenthal Gmbh | Substituierte Aminomethyl-Phenyl-Cyclohexanderivate |
| DE10218862A1 (de) * | 2002-04-26 | 2003-11-06 | Gruenenthal Gmbh | Verfahren zur Chlorierung tertiärer Alkohole |
| DE10233048A1 (de) * | 2002-07-19 | 2004-01-29 | Grünenthal GmbH | Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken |
| DE10356362A1 (de) * | 2003-11-28 | 2005-06-23 | Grünenthal GmbH | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen |
-
2005
- 2005-07-22 DE DE102005034973A patent/DE102005034973A1/de not_active Withdrawn
-
2006
- 2006-07-20 JP JP2008521895A patent/JP5205260B2/ja not_active Expired - Fee Related
- 2006-07-20 DK DK06776326.8T patent/DK1907350T3/da active
- 2006-07-20 SI SI200631292T patent/SI1907350T1/sl unknown
- 2006-07-20 AT AT06776326T patent/ATE540919T1/de active
- 2006-07-20 EP EP06776326A patent/EP1907350B1/de not_active Not-in-force
- 2006-07-20 PT PT06776326T patent/PT1907350E/pt unknown
- 2006-07-20 CA CA002615741A patent/CA2615741A1/en not_active Abandoned
- 2006-07-20 PL PL06776326T patent/PL1907350T3/pl unknown
- 2006-07-20 WO PCT/EP2006/007161 patent/WO2007009793A1/de not_active Ceased
- 2006-07-20 PE PE2006000872A patent/PE20070375A1/es not_active Application Discontinuation
- 2006-07-20 ES ES06776326T patent/ES2380799T3/es active Active
- 2006-07-21 AR ARP060103154A patent/AR057673A1/es not_active Application Discontinuation
-
2012
- 2012-04-04 CY CY20121100333T patent/CY1112741T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5205260B2 (ja) | 2013-06-05 |
| SI1907350T1 (sl) | 2012-04-30 |
| EP1907350A1 (de) | 2008-04-09 |
| DE102005034973A1 (de) | 2007-02-15 |
| EP1907350B1 (de) | 2012-01-11 |
| JP2009502758A (ja) | 2009-01-29 |
| CA2615741A1 (en) | 2007-01-25 |
| ES2380799T3 (es) | 2012-05-18 |
| WO2007009793A1 (de) | 2007-01-25 |
| PT1907350E (pt) | 2012-03-29 |
| AR057673A1 (es) | 2007-12-12 |
| DK1907350T3 (da) | 2012-05-07 |
| PL1907350T3 (pl) | 2012-06-29 |
| PE20070375A1 (es) | 2007-05-12 |
| ATE540919T1 (de) | 2012-01-15 |
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