AR057673A1 - Sal de dimetilaminometil - fenil ciclohexano y su forma cristalina - Google Patents

Sal de dimetilaminometil - fenil ciclohexano y su forma cristalina

Info

Publication number
AR057673A1
AR057673A1 ARP060103154A ARP060103154A AR057673A1 AR 057673 A1 AR057673 A1 AR 057673A1 AR P060103154 A ARP060103154 A AR P060103154A AR P060103154 A ARP060103154 A AR P060103154A AR 057673 A1 AR057673 A1 AR 057673A1
Authority
AR
Argentina
Prior art keywords
cyclhexan
dimethylaminome
phenyl
salt
crystal form
Prior art date
Application number
ARP060103154A
Other languages
English (en)
Inventor
Michael Gruss
W Hell
Jorg Berghausen
Martin Szelagiewicz
Raumer M Von
Paul S M De
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of AR057673A1 publication Critical patent/AR057673A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

El fumarato de 3-[2-(dimetilamino)metil-(cicloex-1-il)]-fenol es un analgésico con muy buen efecto. La forma cristalina B ha demostrado ser muy estable tanto química como físicamente y sirve en especial para la preparacion del principio activo y composiciones farmacéuticas
ARP060103154A 2005-07-22 2006-07-21 Sal de dimetilaminometil - fenil ciclohexano y su forma cristalina AR057673A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005034973A DE102005034973A1 (de) 2005-07-22 2005-07-22 Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen

Publications (1)

Publication Number Publication Date
AR057673A1 true AR057673A1 (es) 2007-12-12

Family

ID=37101332

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060103154A AR057673A1 (es) 2005-07-22 2006-07-21 Sal de dimetilaminometil - fenil ciclohexano y su forma cristalina

Country Status (14)

Country Link
EP (1) EP1907350B1 (es)
JP (1) JP5205260B2 (es)
AR (1) AR057673A1 (es)
AT (1) ATE540919T1 (es)
CA (1) CA2615741A1 (es)
CY (1) CY1112741T1 (es)
DE (1) DE102005034973A1 (es)
DK (1) DK1907350T3 (es)
ES (1) ES2380799T3 (es)
PE (1) PE20070375A1 (es)
PL (1) PL1907350T3 (es)
PT (1) PT1907350E (es)
SI (1) SI1907350T1 (es)
WO (1) WO2007009793A1 (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
DE10218862A1 (de) * 2002-04-26 2003-11-06 Gruenenthal Gmbh Verfahren zur Chlorierung tertiärer Alkohole
DE10233048A1 (de) * 2002-07-19 2004-01-29 Grünenthal GmbH Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen

Also Published As

Publication number Publication date
JP2009502758A (ja) 2009-01-29
CY1112741T1 (el) 2016-02-10
EP1907350B1 (de) 2012-01-11
CA2615741A1 (en) 2007-01-25
JP5205260B2 (ja) 2013-06-05
DK1907350T3 (da) 2012-05-07
ES2380799T3 (es) 2012-05-18
SI1907350T1 (sl) 2012-04-30
EP1907350A1 (de) 2008-04-09
PT1907350E (pt) 2012-03-29
WO2007009793A1 (de) 2007-01-25
ATE540919T1 (de) 2012-01-15
PE20070375A1 (es) 2007-05-12
PL1907350T3 (pl) 2012-06-29
DE102005034973A1 (de) 2007-02-15

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