CY1112034T1 - Μονοδιασπαρμενα μειγματα και μεθοδοι για την θεραπευτικη αγωγη του διαβητη - Google Patents

Μονοδιασπαρμενα μειγματα και μεθοδοι για την θεραπευτικη αγωγη του διαβητη

Info

Publication number
CY1112034T1
CY1112034T1 CY20111100609T CY111100609T CY1112034T1 CY 1112034 T1 CY1112034 T1 CY 1112034T1 CY 20111100609 T CY20111100609 T CY 20111100609T CY 111100609 T CY111100609 T CY 111100609T CY 1112034 T1 CY1112034 T1 CY 1112034T1
Authority
CY
Cyprus
Prior art keywords
methods
patient
treatment
diabetes
mixes
Prior art date
Application number
CY20111100609T
Other languages
English (en)
Inventor
Nnochiri N Ekwuribe
Christopher H Price
James Gordon Still
Jennifer Ann Filbey
Balasingham Radhakrishnan
Amy L Odenbaugh
Aslam M Ansari
Original Assignee
Biocon Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Limited filed Critical Biocon Limited
Publication of CY1112034T1 publication Critical patent/CY1112034T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Μέθοδοι για την θεραπευτική αγωγή του σακχαρώδη διαβήτη σε ασθενείς που χρήζουν τέτοιας αγωγής οι οποίες περιλαμβάνουν τη χορήγηση μιας αποτελεσματικής ποσότητας μιας φαρμακευτικής ουσίας ινσουλίνης στους ασθενείς με σκοπό να αντιμετωπίσουν τον σακχαρώδη διαβήτη στους ασθενείς. Μέθοδοι σύμφωνα με την παρούσα εφεύρεση ενδεχομένως «ενεργοποιούν» το ήπαρ, δυνητικά αποκαθιστώντας τη φυσιολογική ομοιόσταση της γλυκόζης σε άτομα που πάσχουν από σακχαρώδη διαβήτη.
CY20111100609T 2001-02-15 2011-06-27 Μονοδιασπαρμενα μειγματα και μεθοδοι για την θεραπευτικη αγωγη του διαβητη CY1112034T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26919801P 2001-02-15 2001-02-15
US34771302P 2002-01-11 2002-01-11
EP02709541A EP1409006B1 (en) 2001-02-15 2002-02-14 Monodispersed mixtures and methods of treating diabetes

Publications (1)

Publication Number Publication Date
CY1112034T1 true CY1112034T1 (el) 2015-11-04

Family

ID=26953561

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100609T CY1112034T1 (el) 2001-02-15 2011-06-27 Μονοδιασπαρμενα μειγματα και μεθοδοι για την θεραπευτικη αγωγη του διαβητη

Country Status (17)

Country Link
US (3) US7060675B2 (el)
EP (1) EP1409006B1 (el)
JP (1) JP4113778B2 (el)
KR (1) KR100896945B1 (el)
AT (1) ATE503490T1 (el)
AU (1) AU2002244020B2 (el)
BR (1) BRPI0207700B8 (el)
CA (1) CA2437940C (el)
CY (1) CY1112034T1 (el)
DE (1) DE60239612D1 (el)
DK (1) DK1409006T3 (el)
MX (1) MXPA03007374A (el)
NO (1) NO327586B1 (el)
NZ (1) NZ527392A (el)
PT (1) PT1409006E (el)
WO (1) WO2002065985A2 (el)
ZA (1) ZA200306332B (el)

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EP1409006A4 (en) 2005-01-19
BR0207700A (pt) 2005-07-19
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CA2437940A1 (en) 2002-08-29
EP1409006B1 (en) 2011-03-30
NO327586B1 (no) 2009-08-24
US7423014B2 (en) 2008-09-09
WO2002065985A2 (en) 2002-08-29
US20030050228A1 (en) 2003-03-13
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AU2002244020B2 (en) 2007-08-16
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KR20040043113A (ko) 2004-05-22
US7381702B2 (en) 2008-06-03
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US20060100137A1 (en) 2006-05-11
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US7060675B2 (en) 2006-06-13
EP1409006A2 (en) 2004-04-21
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