CY1111714T1 - Δεσμευτικες πρωτεϊνες αυξητικου παραγοντα ηπατοκυτταρων (hgf). - Google Patents

Δεσμευτικες πρωτεϊνες αυξητικου παραγοντα ηπατοκυτταρων (hgf).

Info

Publication number
CY1111714T1
CY1111714T1 CY20111100371T CY111100371T CY1111714T1 CY 1111714 T1 CY1111714 T1 CY 1111714T1 CY 20111100371 T CY20111100371 T CY 20111100371T CY 111100371 T CY111100371 T CY 111100371T CY 1111714 T1 CY1111714 T1 CY 1111714T1
Authority
CY
Cyprus
Prior art keywords
hgf
binding proteins
growth factor
binding
protein growth
Prior art date
Application number
CY20111100371T
Other languages
Greek (el)
English (en)
Inventor
William M Winston
S Kirk Wright
May Han
Lyne Breault
Jie Lin
Bijan Etemad-Gilbertson
Christine Knuehl
Jeno Gyuris
Arnold Horwitz
Original Assignee
Aveo Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aveo Pharmaceuticals, Inc. filed Critical Aveo Pharmaceuticals, Inc.
Publication of CY1111714T1 publication Critical patent/CY1111714T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
CY20111100371T 2006-06-02 2011-04-11 Δεσμευτικες πρωτεϊνες αυξητικου παραγοντα ηπατοκυτταρων (hgf). CY1111714T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81071406P 2006-06-02 2006-06-02
US86050906P 2006-11-21 2006-11-21
EP07795599A EP2027156B9 (en) 2006-06-02 2007-06-01 Hepatocyte growth factor (hgf) binding proteins

Publications (1)

Publication Number Publication Date
CY1111714T1 true CY1111714T1 (el) 2015-10-07

Family

ID=38802077

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100371T CY1111714T1 (el) 2006-06-02 2011-04-11 Δεσμευτικες πρωτεϊνες αυξητικου παραγοντα ηπατοκυτταρων (hgf).

Country Status (20)

Country Link
US (5) US7649083B2 (enExample)
EP (2) EP2027156B9 (enExample)
JP (3) JP4686634B2 (enExample)
KR (1) KR101196060B1 (enExample)
AR (1) AR061171A1 (enExample)
AT (1) ATE495195T1 (enExample)
AU (1) AU2007254942B2 (enExample)
BR (1) BRPI0712222B1 (enExample)
CA (1) CA2654025C (enExample)
CY (1) CY1111714T1 (enExample)
DE (1) DE602007011923D1 (enExample)
DK (1) DK2027156T3 (enExample)
IL (2) IL195037A (enExample)
MX (1) MX2008014829A (enExample)
NO (1) NO345476B1 (enExample)
NZ (1) NZ573818A (enExample)
PL (1) PL2027156T3 (enExample)
PT (1) PT2027156E (enExample)
SG (1) SG158112A1 (enExample)
WO (1) WO2007143090A2 (enExample)

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US9732150B2 (en) * 2013-03-14 2017-08-15 Alderbio Holdings Llc Therapeutic use of antibodies to HGF
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US9062104B2 (en) * 2013-03-14 2015-06-23 Alderbio Holdings Llc Therapeutic use of antibodies to HGF
BR112015025549A2 (pt) * 2013-04-07 2017-10-10 Bioex Therapeutics Inc anticorpo contra o receptor do fator de crescimento epidérmico
WO2015031578A1 (en) * 2013-08-28 2015-03-05 Abbvie Inc. Hgf assay
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KR20170005016A (ko) 2014-05-23 2017-01-11 제넨테크, 인크. MiT 바이오마커 및 그의 사용 방법
CA2958144A1 (en) * 2014-08-15 2016-02-18 Oncomed Pharmaceuticals, Inc. Rspo1 binding agents and uses thereof
WO2016044295A1 (en) 2014-09-16 2016-03-24 Oncomed Pharmaceuticals, Inc. Treatment of fibrotic diseases
WO2017070567A1 (en) * 2015-10-21 2017-04-27 The Research Foundation For The State University Of New York Klebsiella pneumoniae antibodies and methods to treat klebsiella pneumoniae infections
AU2020327537A1 (en) 2019-08-12 2022-03-03 Interna Technologies B.V. New treatments involving miRNA-193a
US20230136088A1 (en) 2020-02-28 2023-05-04 Interna Technologies B.V. miRNA-193a for Promoting Immunogenic Cell Death
CN116234814A (zh) * 2020-08-28 2023-06-06 江苏恒瑞医药股份有限公司 用于降低异源多肽末端异质性的信号肽
KR20240004937A (ko) 2021-05-05 2024-01-11 이매틱스 바이오테크놀로지스 게엠베하 Bma031 항원 결합 폴리펩타이드

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Also Published As

Publication number Publication date
IL219654A0 (en) 2012-06-28
US20100173362A1 (en) 2010-07-08
NO20085421L (no) 2009-02-27
US7943344B2 (en) 2011-05-17
KR101196060B1 (ko) 2012-11-01
MX2008014829A (es) 2009-01-29
BRPI0712222A2 (pt) 2012-01-10
JP2011072318A (ja) 2011-04-14
NZ573818A (en) 2011-09-30
EP2361934A3 (en) 2011-11-02
EP2027156A2 (en) 2009-02-25
PL2027156T3 (pl) 2011-06-30
US7649083B2 (en) 2010-01-19
JP2009539347A (ja) 2009-11-19
AU2007254942A1 (en) 2007-12-13
US20130203963A1 (en) 2013-08-08
JP2013090632A (ja) 2013-05-16
ATE495195T1 (de) 2011-01-15
US20110229462A1 (en) 2011-09-22
HK1129395A1 (en) 2009-11-27
AU2007254942A8 (en) 2009-02-05
AR061171A1 (es) 2008-08-06
AU2007254942A2 (en) 2009-05-28
SG158112A1 (en) 2010-01-29
KR20090027226A (ko) 2009-03-16
CA2654025A1 (en) 2007-12-13
US8273355B2 (en) 2012-09-25
US9096664B2 (en) 2015-08-04
EP2027156B9 (en) 2011-03-30
AU2007254942B2 (en) 2011-10-27
DE602007011923D1 (de) 2011-02-24
JP5735476B2 (ja) 2015-06-17
CA2654025C (en) 2016-08-02
US8580930B2 (en) 2013-11-12
WO2007143090A3 (en) 2008-03-13
NO345476B1 (no) 2021-02-22
EP2027156B1 (en) 2011-01-12
DK2027156T3 (da) 2011-04-26
US20140178935A1 (en) 2014-06-26
IL195037A0 (en) 2011-08-01
EP2361934A2 (en) 2011-08-31
JP4686634B2 (ja) 2011-05-25
BRPI0712222B1 (pt) 2021-10-13
US20080108565A1 (en) 2008-05-08
IL195037A (en) 2015-08-31
WO2007143090A2 (en) 2007-12-13
PT2027156E (pt) 2011-04-18

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