DK2027156T3 - Hepatocytvækstfaktor (HGF)bindingsprotein - Google Patents
Hepatocytvækstfaktor (HGF)bindingsproteinInfo
- Publication number
- DK2027156T3 DK2027156T3 DK07795599.5T DK07795599T DK2027156T3 DK 2027156 T3 DK2027156 T3 DK 2027156T3 DK 07795599 T DK07795599 T DK 07795599T DK 2027156 T3 DK2027156 T3 DK 2027156T3
- Authority
- DK
- Denmark
- Prior art keywords
- hgf
- growth factor
- binding protein
- hepatocyte growth
- hepatocyte
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81071406P | 2006-06-02 | 2006-06-02 | |
US86050906P | 2006-11-21 | 2006-11-21 | |
PCT/US2007/012939 WO2007143090A2 (en) | 2006-06-02 | 2007-06-01 | Hepatocyte growth factor (hgf) binding proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2027156T3 true DK2027156T3 (da) | 2011-04-26 |
Family
ID=38802077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07795599.5T DK2027156T3 (da) | 2006-06-02 | 2007-06-01 | Hepatocytvækstfaktor (HGF)bindingsprotein |
Country Status (21)
Country | Link |
---|---|
US (5) | US7649083B2 (da) |
EP (2) | EP2027156B9 (da) |
JP (3) | JP4686634B2 (da) |
KR (1) | KR101196060B1 (da) |
AR (1) | AR061171A1 (da) |
AT (1) | ATE495195T1 (da) |
AU (1) | AU2007254942B2 (da) |
BR (1) | BRPI0712222B1 (da) |
CA (1) | CA2654025C (da) |
CY (1) | CY1111714T1 (da) |
DE (1) | DE602007011923D1 (da) |
DK (1) | DK2027156T3 (da) |
HK (1) | HK1129395A1 (da) |
IL (2) | IL195037A (da) |
MX (1) | MX2008014829A (da) |
NO (1) | NO345476B1 (da) |
NZ (1) | NZ573818A (da) |
PL (1) | PL2027156T3 (da) |
PT (1) | PT2027156E (da) |
SG (1) | SG158112A1 (da) |
WO (1) | WO2007143090A2 (da) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS53476B (en) | 2003-07-18 | 2014-12-31 | Amgen Fremont Inc. | Hepatocyte Growth Factor Binders |
WO2007143090A2 (en) * | 2006-06-02 | 2007-12-13 | Aveo Pharmaceuticals, Inc. | Hepatocyte growth factor (hgf) binding proteins |
EP2380908A1 (en) * | 2006-06-02 | 2011-10-26 | Aveo Pharmaceuticals, Inc. | Hepatocyte growth factor (hgf) binding proteins |
US20080233660A1 (en) * | 2007-03-23 | 2008-09-25 | Mu Bioteknik Ab | Solid phase labeling method |
HUE027154T2 (en) | 2007-07-02 | 2016-08-29 | Oncomed Pharm Inc | Preparations and procedures for the treatment and diagnosis of cancer |
EA201000903A1 (ru) | 2007-11-30 | 2011-02-28 | Калобиос Фармасьютикалс, Инк. | Антитела к pcrv-антигену pseudomonas aeruginosa |
NZ588029A (en) * | 2008-03-14 | 2012-12-21 | Allergan Inc | Immuno-based botulinum toxin serotype a activity assays |
WO2009148928A1 (en) | 2008-05-29 | 2009-12-10 | Galaxy Biotech, Llc | Monoclonal antibodies to basic fibroblast growth factor |
MX2011000455A (es) | 2008-11-07 | 2011-02-25 | Galaxy Biotech Llc | Anticuerpos monoclonales especificos al receptor 2 del factor de crecimiento de fibroblastos. |
WO2010119991A2 (en) | 2009-04-17 | 2010-10-21 | Takeda Pharmaceutical Company Limited | Novel method of treating cancer |
WO2012003338A1 (en) | 2010-07-01 | 2012-01-05 | Takeda Pharmaceutical Company Limited | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET |
US20120089541A1 (en) | 2010-08-31 | 2012-04-12 | Genentech, Inc. | Biomarkers and methods of treatment |
ES2865068T3 (es) | 2011-01-14 | 2021-10-14 | Univ California | Anticuerpos terapéuticos contra la proteína ROR-1 y métodos para usarlos |
KR20140048276A (ko) | 2011-07-15 | 2014-04-23 | 온코메드 파마슈티칼스, 인크. | Rspo 결합제 및 이의 용도 |
MX2014002762A (es) | 2011-09-09 | 2014-07-30 | Amgen Inc | Uso de proteina c-met para predecir la eficacia de anticuerpos de factor de crecimiento de anti-hepatocitos (hgf) en pacientes con cancer esofagico y gastrico. |
SG11201400724SA (en) | 2011-09-19 | 2014-04-28 | Genentech Inc | Combination treatments comprising c-met antagonists and b-raf antagonists |
KR20150036603A (ko) | 2012-07-13 | 2015-04-07 | 온코메드 파마슈티칼스, 인크. | Rspo3 결합제 및 그의 용도 |
JP2016509045A (ja) | 2013-02-22 | 2016-03-24 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | がんを治療し、薬剤耐性を防止する方法 |
WO2014153166A2 (en) * | 2013-03-14 | 2014-09-25 | Alder Biopharmaceuticals, Inc. | Therapeutic use of antibodies to hgf |
US9062104B2 (en) | 2013-03-14 | 2015-06-23 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
US9732150B2 (en) * | 2013-03-14 | 2017-08-15 | Alderbio Holdings Llc | Therapeutic use of antibodies to HGF |
US9481725B2 (en) | 2013-03-14 | 2016-11-01 | Alderbio Holdings, Llc | Antibodies to HGF and compositions containing |
RU2652880C2 (ru) * | 2013-04-07 | 2018-05-03 | Дженрикс (Шанхай) Байофармасертикал Ко., Лтд. | Антитело против рецептора эпидермального фактора роста |
WO2015031578A1 (en) * | 2013-08-28 | 2015-03-05 | Abbvie Inc. | Hgf assay |
RU2016141385A (ru) | 2014-03-24 | 2018-04-28 | Дженентек, Инк. | Лечение рака антагонистами с-мет и их корреляция с экспрессией hgf |
WO2015179835A2 (en) | 2014-05-23 | 2015-11-26 | Genentech, Inc. | Mit biomarkers and methods using the same |
EP3180027A4 (en) * | 2014-08-15 | 2018-01-10 | Oncomed Pharmaceuticals, Inc. | Rspo1 binding agents and uses thereof |
TW201628648A (zh) | 2014-09-16 | 2016-08-16 | 安可美德藥物股份有限公司 | 纖維變性疾病之治療 |
WO2017070567A1 (en) * | 2015-10-21 | 2017-04-27 | The Research Foundation For The State University Of New York | Klebsiella pneumoniae antibodies and methods to treat klebsiella pneumoniae infections |
EP4013869A1 (en) | 2019-08-12 | 2022-06-22 | InteRNA Technologies B.V. | New treatments involving mirna-193a |
CA3167367A1 (en) | 2020-02-28 | 2021-09-02 | Sanaz YAHYANEJAD | Mirna-193a for promoting immunogenic cell death |
CN116234814A (zh) * | 2020-08-28 | 2023-06-06 | 江苏恒瑞医药股份有限公司 | 用于降低异源多肽末端异质性的信号肽 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
US6893625B1 (en) | 1986-10-27 | 2005-05-17 | Royalty Pharma Finance Trust | Chimeric antibody with specificity to human B cell surface antigen |
IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
ES2202310T3 (es) | 1991-12-13 | 2004-04-01 | Xoma Corporation | Metodos y materiales para la preparacion de dominios variables de anticuerpos modificados y sus usos terapeuticos. |
US5869619A (en) | 1991-12-13 | 1999-02-09 | Xoma Corporation | Modified antibody variable domains |
DE69334255D1 (de) | 1992-02-06 | 2009-02-12 | Novartis Vaccines & Diagnostic | Marker für Krebs und biosynthetisches Bindeprotein dafür |
US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
US6066718A (en) | 1992-09-25 | 2000-05-23 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
US6498144B1 (en) * | 1993-10-18 | 2002-12-24 | North Shore - Long Island Jewish Research Institute | Use of scatter factor to enhance angiogenesis |
US5837676A (en) | 1993-10-18 | 1998-11-17 | Long Island Jewish Medical Center | Use of scatter factor to enhance angiogenesis |
US5707624A (en) | 1994-06-03 | 1998-01-13 | The Regents Of The University Of Michigan | Treatment of Kaposi's sarcoma by inhibition of scatter factor |
EP1500329B1 (en) | 1996-12-03 | 2012-03-21 | Amgen Fremont Inc. | Human antibodies that specifically bind human TNF alpha |
US6872518B2 (en) | 1997-09-22 | 2005-03-29 | University Of Rochester | Methods for selecting polynucleotides encoding T cell epitopes |
AU1598801A (en) | 1999-11-09 | 2001-06-06 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | HGF-SF monoclonal antibody combinations |
WO2004006955A1 (en) | 2001-07-12 | 2004-01-22 | Jefferson Foote | Super humanized antibodies |
US7220410B2 (en) | 2003-04-18 | 2007-05-22 | Galaxy Biotech, Llc | Monoclonal antibodies to hepatocyte growth factor |
US20040208876A1 (en) | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
RS53476B (en) | 2003-07-18 | 2014-12-31 | Amgen Fremont Inc. | Hepatocyte Growth Factor Binders |
KR100556660B1 (ko) | 2003-11-11 | 2006-03-10 | 국립암센터 | Hgf의 중화가능 에피토프 및 이에 결합하는 중화 항체 |
EP1885400A4 (en) | 2005-06-02 | 2011-01-26 | Galaxy Biotech Llc | METHOD FOR THE TREATMENT OF BRAIN TUMORS BY ANTIBODIES |
AR059922A1 (es) | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
WO2007143090A2 (en) | 2006-06-02 | 2007-12-13 | Aveo Pharmaceuticals, Inc. | Hepatocyte growth factor (hgf) binding proteins |
EP2380908A1 (en) | 2006-06-02 | 2011-10-26 | Aveo Pharmaceuticals, Inc. | Hepatocyte growth factor (hgf) binding proteins |
KR100829972B1 (ko) | 2006-07-14 | 2008-05-16 | 재단법인서울대학교산학협력재단 | 항-hgf/sf 인간화 항체 및 이의 제조방법 |
KR100881825B1 (ko) * | 2007-07-27 | 2009-02-03 | 주식회사 하이닉스반도체 | 반도체 소자 및 그 제조 방법 |
-
2007
- 2007-06-01 WO PCT/US2007/012939 patent/WO2007143090A2/en active Application Filing
- 2007-06-01 EP EP07795599A patent/EP2027156B9/en active Active
- 2007-06-01 PT PT07795599T patent/PT2027156E/pt unknown
- 2007-06-01 JP JP2009513295A patent/JP4686634B2/ja active Active
- 2007-06-01 AU AU2007254942A patent/AU2007254942B2/en active Active
- 2007-06-01 MX MX2008014829A patent/MX2008014829A/es active IP Right Grant
- 2007-06-01 US US11/757,059 patent/US7649083B2/en active Active
- 2007-06-01 EP EP11150489A patent/EP2361934A3/en not_active Withdrawn
- 2007-06-01 BR BRPI0712222-5A patent/BRPI0712222B1/pt active IP Right Grant
- 2007-06-01 DK DK07795599.5T patent/DK2027156T3/da active
- 2007-06-01 SG SG200908089-6A patent/SG158112A1/en unknown
- 2007-06-01 NO NO20085421A patent/NO345476B1/no not_active Application Discontinuation
- 2007-06-01 NZ NZ573818A patent/NZ573818A/en unknown
- 2007-06-01 AT AT07795599T patent/ATE495195T1/de active
- 2007-06-01 PL PL07795599T patent/PL2027156T3/pl unknown
- 2007-06-01 DE DE602007011923T patent/DE602007011923D1/de active Active
- 2007-06-01 KR KR1020087032083A patent/KR101196060B1/ko active IP Right Grant
- 2007-06-01 AR ARP070102389A patent/AR061171A1/es active IP Right Grant
- 2007-06-01 CA CA2654025A patent/CA2654025C/en active Active
-
2008
- 2008-11-02 IL IL195037A patent/IL195037A/en active IP Right Grant
-
2009
- 2009-08-13 HK HK09107470.5A patent/HK1129395A1/xx unknown
- 2009-12-07 US US12/632,765 patent/US7943344B2/en active Active
-
2010
- 2010-12-28 JP JP2010294222A patent/JP2011072318A/ja not_active Withdrawn
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2011
- 2011-03-18 US US13/051,481 patent/US8273355B2/en active Active
- 2011-04-11 CY CY20111100371T patent/CY1111714T1/el unknown
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2012
- 2012-05-08 IL IL219654A patent/IL219654A0/en unknown
- 2012-08-20 US US13/589,664 patent/US8580930B2/en active Active
- 2012-12-10 JP JP2012269474A patent/JP5735476B2/ja active Active
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2013
- 2013-10-02 US US14/044,278 patent/US9096664B2/en active Active
Also Published As
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