CY1111273T1 - Συνδυασμενη χρηση της l-καρνιτινης, ακετυλο l-καρνιτινης και προπιονυλο l-καρνιτινης για τη θεραπεια της ολιγοασθενοτερατοσπερμιας - Google Patents
Συνδυασμενη χρηση της l-καρνιτινης, ακετυλο l-καρνιτινης και προπιονυλο l-καρνιτινης για τη θεραπεια της ολιγοασθενοτερατοσπερμιαςInfo
- Publication number
- CY1111273T1 CY1111273T1 CY20101100989T CY101100989T CY1111273T1 CY 1111273 T1 CY1111273 T1 CY 1111273T1 CY 20101100989 T CY20101100989 T CY 20101100989T CY 101100989 T CY101100989 T CY 101100989T CY 1111273 T1 CY1111273 T1 CY 1111273T1
- Authority
- CY
- Cyprus
- Prior art keywords
- carnitine
- treatment
- acetyl
- oligosaccharide
- propylene
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 2
- -1 L-carnitine propylene Chemical group 0.000 title 1
- 229920001542 oligosaccharide Polymers 0.000 title 1
- 150000002482 oligosaccharides Chemical class 0.000 title 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000194A ITRM20020194A1 (it) | 2002-04-09 | 2002-04-09 | Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo. |
| EP03720869A EP1492521B1 (en) | 2002-04-09 | 2003-04-08 | Combined use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine for the treatment of oligoasthenoteratospermia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111273T1 true CY1111273T1 (el) | 2015-08-05 |
Family
ID=11456235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101100989T CY1111273T1 (el) | 2002-04-09 | 2010-11-03 | Συνδυασμενη χρηση της l-καρνιτινης, ακετυλο l-καρνιτινης και προπιονυλο l-καρνιτινης για τη θεραπεια της ολιγοασθενοτερατοσπερμιας |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20050107470A1 (https=) |
| EP (1) | EP1492521B1 (https=) |
| JP (1) | JP4663987B2 (https=) |
| KR (1) | KR20040098005A (https=) |
| CN (1) | CN1330301C (https=) |
| AT (1) | ATE476974T1 (https=) |
| AU (1) | AU2003224443B2 (https=) |
| BR (1) | BR0309055A (https=) |
| CA (1) | CA2478674C (https=) |
| CY (1) | CY1111273T1 (https=) |
| DE (1) | DE60333742D1 (https=) |
| DK (1) | DK1492521T3 (https=) |
| ES (1) | ES2350338T3 (https=) |
| IT (1) | ITRM20020194A1 (https=) |
| MX (1) | MXPA04009763A (https=) |
| PL (1) | PL214859B1 (https=) |
| PT (1) | PT1492521E (https=) |
| SI (1) | SI1492521T1 (https=) |
| WO (1) | WO2003084526A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776913B2 (en) | 2002-12-13 | 2010-08-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Carnitines for treating or preventing disorders caused by andropause |
| ES2587977T3 (es) * | 2009-05-01 | 2016-10-28 | Celloxess Llc | Tratamiento de la infertilidad masculina secundaria al estrés oxidativo de esperma |
| US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
| US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
| CN108041588A (zh) * | 2017-12-08 | 2018-05-18 | 冯纪敏 | 一种含有海藻糖的组合物及其应用 |
| CN109999042B (zh) * | 2019-05-16 | 2021-05-18 | 北京华睿鼎信科技有限公司 | 包含脱氢表雄酮或其硫酸酯、左卡尼汀、乙酰左卡尼汀或它们的可药用盐的组合物及其应用 |
| CN118435893B (zh) * | 2024-05-17 | 2025-12-19 | 北部湾大学 | L-乙酰肉碱提升香港牡蛎繁殖性能的方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1249462B (it) * | 1991-10-21 | 1995-02-23 | Sigma Tau Ind Farmaceuti | Impiego di l-carnitina e acil l-carnitine nel trattamento delle oligoastenospermie idiopatiche. |
| IT1291127B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
| IT1295408B1 (it) * | 1997-10-03 | 1999-05-12 | Sigma Tau Ind Farmaceuti | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
| GB9721746D0 (en) | 1997-10-15 | 1997-12-10 | Panos Therapeutics Limited | Compositions |
| US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
| ITRM20010029A1 (it) * | 2001-01-23 | 2002-07-23 | Aldo Fassi | Sali metallici di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per |
| ITRM20020055A1 (it) | 2002-02-04 | 2003-08-04 | Aldo Fassi | Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti |
-
2002
- 2002-04-09 IT IT2002RM000194A patent/ITRM20020194A1/it unknown
-
2003
- 2003-04-08 CA CA2478674A patent/CA2478674C/en not_active Expired - Lifetime
- 2003-04-08 AT AT03720869T patent/ATE476974T1/de active
- 2003-04-08 AU AU2003224443A patent/AU2003224443B2/en not_active Expired
- 2003-04-08 US US10/510,450 patent/US20050107470A1/en not_active Abandoned
- 2003-04-08 SI SI200331892T patent/SI1492521T1/sl unknown
- 2003-04-08 CN CNB038050935A patent/CN1330301C/zh not_active Expired - Lifetime
- 2003-04-08 WO PCT/IT2003/000214 patent/WO2003084526A1/en not_active Ceased
- 2003-04-08 JP JP2003581766A patent/JP4663987B2/ja not_active Expired - Lifetime
- 2003-04-08 DE DE60333742T patent/DE60333742D1/de not_active Expired - Lifetime
- 2003-04-08 PT PT03720869T patent/PT1492521E/pt unknown
- 2003-04-08 EP EP03720869A patent/EP1492521B1/en not_active Expired - Lifetime
- 2003-04-08 MX MXPA04009763A patent/MXPA04009763A/es active IP Right Grant
- 2003-04-08 BR BR0309055-8A patent/BR0309055A/pt not_active Application Discontinuation
- 2003-04-08 PL PL372924A patent/PL214859B1/pl unknown
- 2003-04-08 DK DK03720869.1T patent/DK1492521T3/da active
- 2003-04-08 KR KR10-2004-7013385A patent/KR20040098005A/ko not_active Ceased
- 2003-04-08 ES ES03720869T patent/ES2350338T3/es not_active Expired - Lifetime
-
2008
- 2008-09-09 US US12/230,992 patent/US8415392B2/en not_active Expired - Fee Related
-
2010
- 2010-11-03 CY CY20101100989T patent/CY1111273T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1492521B1 (en) | 2010-08-11 |
| PT1492521E (pt) | 2010-11-11 |
| DK1492521T3 (da) | 2010-11-22 |
| EP1492521A1 (en) | 2005-01-05 |
| WO2003084526A1 (en) | 2003-10-16 |
| ITRM20020194A0 (it) | 2002-04-09 |
| HK1078460A1 (en) | 2006-03-17 |
| JP4663987B2 (ja) | 2011-04-06 |
| AU2003224443B2 (en) | 2008-09-11 |
| US8415392B2 (en) | 2013-04-09 |
| ATE476974T1 (de) | 2010-08-15 |
| MXPA04009763A (es) | 2004-12-13 |
| ITRM20020194A1 (it) | 2003-10-09 |
| AU2003224443A1 (en) | 2003-10-20 |
| BR0309055A (pt) | 2005-02-22 |
| US20050107470A1 (en) | 2005-05-19 |
| CA2478674C (en) | 2010-10-19 |
| US20090012169A1 (en) | 2009-01-08 |
| DE60333742D1 (de) | 2010-09-23 |
| SI1492521T1 (sl) | 2010-12-31 |
| JP2006505499A (ja) | 2006-02-16 |
| PL214859B1 (pl) | 2013-09-30 |
| CA2478674A1 (en) | 2003-10-16 |
| CN1330301C (zh) | 2007-08-08 |
| ES2350338T3 (es) | 2011-01-21 |
| CN1638754A (zh) | 2005-07-13 |
| PL372924A1 (en) | 2005-08-08 |
| KR20040098005A (ko) | 2004-11-18 |
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