CY1105655T1 - Φαρμακευτικη οροδιασπειρομενη συνθεση περινδοπριλης - Google Patents

Φαρμακευτικη οροδιασπειρομενη συνθεση περινδοπριλης

Info

Publication number
CY1105655T1
CY1105655T1 CY20061101450T CY061101450T CY1105655T1 CY 1105655 T1 CY1105655 T1 CY 1105655T1 CY 20061101450 T CY20061101450 T CY 20061101450T CY 061101450 T CY061101450 T CY 061101450T CY 1105655 T1 CY1105655 T1 CY 1105655T1
Authority
CY
Cyprus
Prior art keywords
perindopril
orodisperable
pharmaceutical
composition
lactose
Prior art date
Application number
CY20061101450T
Other languages
English (en)
Inventor
Patrick Wuthrich
Herve Rolland
Marc Julien
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of CY1105655T1 publication Critical patent/CY1105655T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η εφεύρεση έχει ως αντικείμενο μια στερεά οροδιασπειρόμενη φαρμακευτική σύνθεση περινδοπρίλης, η οποία χαρακτηρίζεται από το ότι περιέχει περινδοπρίλη ή ένα από τα φαρμακευτικώς αποδεκτά άλατα της και κόκκους που αποτελούνται από λακτόζη και άμυλο που έχουν ξηρανθεί από κοινού.
CY20061101450T 2002-01-23 2006-10-10 Φαρμακευτικη οροδιασπειρομενη συνθεση περινδοπριλης CY1105655T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0200790A FR2834893B1 (fr) 2002-01-23 2002-01-23 Composition pharmaceutique orodispersible de perindopril
PCT/FR2003/000200 WO2003061691A1 (fr) 2002-01-23 2003-01-22 Composition pharmaceutique orodispersible de perindopril

Publications (1)

Publication Number Publication Date
CY1105655T1 true CY1105655T1 (el) 2010-12-22

Family

ID=27589554

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101450T CY1105655T1 (el) 2002-01-23 2006-10-10 Φαρμακευτικη οροδιασπειρομενη συνθεση περινδοπριλης

Country Status (27)

Country Link
US (3) US20050106237A1 (el)
EP (1) EP1467750B1 (el)
JP (1) JP4090997B2 (el)
KR (1) KR100588224B1 (el)
CN (1) CN1658898B (el)
AR (1) AR038305A1 (el)
AT (1) ATE332690T1 (el)
AU (1) AU2003215708B2 (el)
BR (1) BRPI0307048B1 (el)
CA (1) CA2473205C (el)
CY (1) CY1105655T1 (el)
DE (1) DE60306747T2 (el)
DK (1) DK1467750T3 (el)
EA (1) EA007181B1 (el)
ES (1) ES2268372T3 (el)
FR (1) FR2834893B1 (el)
GE (1) GEP20063821B (el)
HK (1) HK1076743A1 (el)
MA (1) MA27099A1 (el)
MX (1) MXPA04007195A (el)
NO (1) NO333723B1 (el)
NZ (1) NZ533821A (el)
PL (1) PL205473B1 (el)
PT (1) PT1467750E (el)
UA (1) UA78279C2 (el)
WO (1) WO2003061691A1 (el)
ZA (1) ZA200405009B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067887A2 (en) * 2004-03-24 2005-07-28 Actavis Group Formulations of ramipril
DE102004019845A1 (de) * 2004-03-29 2005-10-20 Krka Tovarna Zdravil D D Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung
SK50252005A3 (sk) * 2005-03-22 2006-10-05 Vúlm, A.S. Farmaceutický prípravok obsahujúci perindopril erbumín, spôsob jeho prípravy a stabilizácie
GB0518129D0 (en) * 2005-09-06 2005-10-12 Arrow Int Ltd Ramipril formulation
US20070098782A1 (en) * 2005-10-28 2007-05-03 Selamine Limited Ramipril Formulation
GB2431579A (en) * 2005-10-28 2007-05-02 Arrow Int Ltd Ramipril formulations
GB0624084D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amino acid salts
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
GB0624090D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amine salts
FI2886108T4 (fi) * 2013-12-23 2023-02-22 Optimoitu farmaseuttinen koostumus ruokatorven tulehduksellisten muutosten hoitoon
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3506276C1 (de) * 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
JP3122141B2 (ja) * 1994-01-31 2001-01-09 山之内製薬株式会社 口腔内溶解型圧縮成型物及びその製造法
CA2322315C (en) * 1998-03-06 2008-09-16 Eurand International S.P.A. Fast disintegrating tablets
WO2000078292A1 (fr) * 1999-06-18 2000-12-28 Takeda Chemical Industries, Ltd. Preparations solides a desintegration rapide
FR2811318B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
ES2292414T3 (es) * 2000-07-27 2008-03-16 Roquette Freres Granulos a base de almidon y de lactosa.
US6651768B2 (en) * 2000-11-06 2003-11-25 Bombardier Inc. Snowmobile engine mount
FR2834889B1 (fr) * 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible

Also Published As

Publication number Publication date
PL370162A1 (en) 2005-05-16
PL205473B1 (pl) 2010-04-30
MA27099A1 (fr) 2004-12-20
PT1467750E (pt) 2006-11-30
KR20040078130A (ko) 2004-09-08
DE60306747T2 (de) 2007-08-02
NZ533821A (en) 2005-08-26
EP1467750A1 (fr) 2004-10-20
AU2003215708B9 (en) 2003-09-02
WO2003061691A1 (fr) 2003-07-31
UA78279C2 (en) 2007-03-15
NO20043473L (no) 2004-08-20
ATE332690T1 (de) 2006-08-15
FR2834893A1 (fr) 2003-07-25
NO333723B1 (no) 2013-09-02
ES2268372T3 (es) 2007-03-16
US20100267799A1 (en) 2010-10-21
HK1076743A1 (en) 2006-01-27
FR2834893B1 (fr) 2004-02-27
JP2005523256A (ja) 2005-08-04
US20050106237A1 (en) 2005-05-19
BR0307048A (pt) 2004-10-26
KR100588224B1 (ko) 2006-06-12
AR038305A1 (es) 2005-01-12
CA2473205C (fr) 2010-05-18
EA200400884A1 (ru) 2004-12-30
EA007181B1 (ru) 2006-08-25
EP1467750B1 (fr) 2006-07-12
MXPA04007195A (es) 2004-10-29
GEP20063821B (en) 2006-05-10
CN1658898A (zh) 2005-08-24
AU2003215708B8 (en) 2003-09-02
BRPI0307048B1 (pt) 2015-06-30
CA2473205A1 (fr) 2003-07-31
CN1658898B (zh) 2012-10-03
ZA200405009B (en) 2005-08-31
US20120076856A1 (en) 2012-03-29
DK1467750T3 (da) 2006-11-13
DE60306747D1 (de) 2006-08-24
JP4090997B2 (ja) 2008-05-28
AU2003215708B2 (en) 2007-07-19

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