AU2003224443B2 - Combined use of L-carnitine, acetyl L-carnitine and propionyl L-carnitine for the treatment of oligoasthenoteratospermia - Google Patents

Combined use of L-carnitine, acetyl L-carnitine and propionyl L-carnitine for the treatment of oligoasthenoteratospermia Download PDF

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Publication number
AU2003224443B2
AU2003224443B2 AU2003224443A AU2003224443A AU2003224443B2 AU 2003224443 B2 AU2003224443 B2 AU 2003224443B2 AU 2003224443 A AU2003224443 A AU 2003224443A AU 2003224443 A AU2003224443 A AU 2003224443A AU 2003224443 B2 AU2003224443 B2 AU 2003224443B2
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AU
Australia
Prior art keywords
carnitine
acetyl
propionyl
treatment
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2003224443A
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English (en)
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AU2003224443A1 (en
Inventor
Giulio Biagiotti
Giorgio Cavallini
Aleardo Koverech
Francesca Sardelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfasigma SpA
Original Assignee
Alfasigma SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of AU2003224443A1 publication Critical patent/AU2003224443A1/en
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Assigned to Alfasigma S.p.A reassignment Alfasigma S.p.A Request for Assignment Assignors: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2003224443A 2002-04-09 2003-04-08 Combined use of L-carnitine, acetyl L-carnitine and propionyl L-carnitine for the treatment of oligoasthenoteratospermia Expired AU2003224443B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2002RM000194A ITRM20020194A1 (it) 2002-04-09 2002-04-09 Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo.
ITRM2002A000194 2002-04-09
PCT/IT2003/000214 WO2003084526A1 (en) 2002-04-09 2003-04-08 Combined use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine for the treatment of oligoasthenoteratospermia

Publications (2)

Publication Number Publication Date
AU2003224443A1 AU2003224443A1 (en) 2003-10-20
AU2003224443B2 true AU2003224443B2 (en) 2008-09-11

Family

ID=11456235

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003224443A Expired AU2003224443B2 (en) 2002-04-09 2003-04-08 Combined use of L-carnitine, acetyl L-carnitine and propionyl L-carnitine for the treatment of oligoasthenoteratospermia

Country Status (19)

Country Link
US (2) US20050107470A1 (https=)
EP (1) EP1492521B1 (https=)
JP (1) JP4663987B2 (https=)
KR (1) KR20040098005A (https=)
CN (1) CN1330301C (https=)
AT (1) ATE476974T1 (https=)
AU (1) AU2003224443B2 (https=)
BR (1) BR0309055A (https=)
CA (1) CA2478674C (https=)
CY (1) CY1111273T1 (https=)
DE (1) DE60333742D1 (https=)
DK (1) DK1492521T3 (https=)
ES (1) ES2350338T3 (https=)
IT (1) ITRM20020194A1 (https=)
MX (1) MXPA04009763A (https=)
PL (1) PL214859B1 (https=)
PT (1) PT1492521E (https=)
SI (1) SI1492521T1 (https=)
WO (1) WO2003084526A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7776913B2 (en) 2002-12-13 2010-08-17 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Carnitines for treating or preventing disorders caused by andropause
ES2587977T3 (es) * 2009-05-01 2016-10-28 Celloxess Llc Tratamiento de la infertilidad masculina secundaria al estrés oxidativo de esperma
US20110015154A1 (en) * 2009-07-20 2011-01-20 Kellermann Gottfried H Supporting acetylcholine function
US20110098265A1 (en) * 2009-10-28 2011-04-28 Neuroscience, Inc. Methods for reducing cravings and impulses associated with addictive and compulsive behaviors
CN108041588A (zh) * 2017-12-08 2018-05-18 冯纪敏 一种含有海藻糖的组合物及其应用
CN109999042B (zh) * 2019-05-16 2021-05-18 北京华睿鼎信科技有限公司 包含脱氢表雄酮或其硫酸酯、左卡尼汀、乙酰左卡尼汀或它们的可药用盐的组合物及其应用
CN118435893B (zh) * 2024-05-17 2025-12-19 北部湾大学 L-乙酰肉碱提升香港牡蛎繁殖性能的方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539336A1 (en) * 1991-10-21 1993-04-28 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of L-carnitine or of acyl L-carnitine for the treatment of idiopathic oligoasthenospermias
WO1999017623A1 (en) * 1997-10-03 1999-04-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects
WO1999027925A1 (en) * 1997-12-01 1999-06-10 Sigma-Tau Healthscience S.P.A. Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
GB9721746D0 (en) 1997-10-15 1997-12-10 Panos Therapeutics Limited Compositions
ITRM20010029A1 (it) * 2001-01-23 2002-07-23 Aldo Fassi Sali metallici di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per
ITRM20020055A1 (it) 2002-02-04 2003-08-04 Aldo Fassi Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539336A1 (en) * 1991-10-21 1993-04-28 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of L-carnitine or of acyl L-carnitine for the treatment of idiopathic oligoasthenospermias
WO1999017623A1 (en) * 1997-10-03 1999-04-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects
WO1999027925A1 (en) * 1997-12-01 1999-06-10 Sigma-Tau Healthscience S.P.A. Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans

Also Published As

Publication number Publication date
EP1492521B1 (en) 2010-08-11
PT1492521E (pt) 2010-11-11
DK1492521T3 (da) 2010-11-22
EP1492521A1 (en) 2005-01-05
WO2003084526A1 (en) 2003-10-16
ITRM20020194A0 (it) 2002-04-09
HK1078460A1 (en) 2006-03-17
JP4663987B2 (ja) 2011-04-06
US8415392B2 (en) 2013-04-09
ATE476974T1 (de) 2010-08-15
MXPA04009763A (es) 2004-12-13
ITRM20020194A1 (it) 2003-10-09
AU2003224443A1 (en) 2003-10-20
CY1111273T1 (el) 2015-08-05
BR0309055A (pt) 2005-02-22
US20050107470A1 (en) 2005-05-19
CA2478674C (en) 2010-10-19
US20090012169A1 (en) 2009-01-08
DE60333742D1 (de) 2010-09-23
SI1492521T1 (sl) 2010-12-31
JP2006505499A (ja) 2006-02-16
PL214859B1 (pl) 2013-09-30
CA2478674A1 (en) 2003-10-16
CN1330301C (zh) 2007-08-08
ES2350338T3 (es) 2011-01-21
CN1638754A (zh) 2005-07-13
PL372924A1 (en) 2005-08-08
KR20040098005A (ko) 2004-11-18

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: ALFASIGMA S.P.A

Free format text: FORMER OWNER(S): SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired