CY1111014T1 - Μεθοδος για τη βελτιωση της βιοδιαθεσιμοτητας της οσπεμιφενης - Google Patents
Μεθοδος για τη βελτιωση της βιοδιαθεσιμοτητας της οσπεμιφενηςInfo
- Publication number
- CY1111014T1 CY1111014T1 CY20081100456T CY081100456T CY1111014T1 CY 1111014 T1 CY1111014 T1 CY 1111014T1 CY 20081100456 T CY20081100456 T CY 20081100456T CY 081100456 T CY081100456 T CY 081100456T CY 1111014 T1 CY1111014 T1 CY 1111014T1
- Authority
- CY
- Cyprus
- Prior art keywords
- improving
- odemphenfine
- biodiversity
- prevention
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 206010067994 Mucosal atrophy Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 206010040799 Skin atrophy Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- LUMKNAVTFCDUIE-VHXPQNKSSA-N ospemifene Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-VHXPQNKSSA-N 0.000 abstract 1
- 229960003969 ospemifene Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physiology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/777,211 US8236861B2 (en) | 2004-02-13 | 2004-02-13 | Method for enhancing the bioavailablity of ospemifene |
| EP05701734A EP1713458B1 (en) | 2004-02-13 | 2005-01-14 | Method for enhancing the bioavailability of ospemifene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111014T1 true CY1111014T1 (el) | 2015-06-11 |
Family
ID=34837941
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081100456T CY1111014T1 (el) | 2004-02-13 | 2008-04-24 | Μεθοδος για τη βελτιωση της βιοδιαθεσιμοτητας της οσπεμιφενης |
| CY2015027C CY2015027I1 (el) | 2004-02-13 | 2015-07-08 | Μεθοδος για τη βελτιωση της βιοδιαθεσιμοτητας της οσπεμιφενης |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY2015027C CY2015027I1 (el) | 2004-02-13 | 2015-07-08 | Μεθοδος για τη βελτιωση της βιοδιαθεσιμοτητας της οσπεμιφενης |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US8236861B2 (h) |
| EP (1) | EP1713458B1 (h) |
| JP (2) | JP5577011B2 (h) |
| CN (1) | CN1925847A (h) |
| AT (1) | ATE387910T1 (h) |
| AU (1) | AU2005211958B2 (h) |
| BE (1) | BE2015C033I2 (h) |
| BR (1) | BRPI0507661A (h) |
| CA (1) | CA2556089C (h) |
| CY (2) | CY1111014T1 (h) |
| DE (1) | DE602005005165T2 (h) |
| DK (1) | DK1713458T5 (h) |
| ES (1) | ES2302177T3 (h) |
| FR (1) | FR15C0041I2 (h) |
| HU (1) | HUS1500030I1 (h) |
| LT (1) | LTC1713458I2 (h) |
| LU (1) | LU92736I2 (h) |
| MX (1) | MXPA06009274A (h) |
| NO (2) | NO337656B1 (h) |
| PL (1) | PL1713458T3 (h) |
| PT (1) | PT1713458E (h) |
| RU (1) | RU2385716C2 (h) |
| WO (1) | WO2005077350A1 (h) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8236861B2 (en) | 2004-02-13 | 2012-08-07 | Hormos Medical Corporation | Method for enhancing the bioavailablity of ospemifene |
| US8642079B2 (en) * | 2004-02-23 | 2014-02-04 | Hormos Medical Corporation | Solid formulations of ospemifene |
| US8758821B2 (en) * | 2004-05-04 | 2014-06-24 | Hormos Medical Ltd. | Oral formulations of ospemifene |
| BRPI0510465B8 (pt) | 2004-05-04 | 2021-05-25 | Hormos Medical Ltd | formulação de droga oral líquida em forma de solução e formulação de droga oral líquida ou semi-sólida |
| US20070104743A1 (en) * | 2005-11-09 | 2007-05-10 | Hormos Medical Ltd. | Formulations of fispemifene |
| US8158828B2 (en) * | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
| US20090062341A1 (en) * | 2005-11-28 | 2009-03-05 | Dalton James T | Nuclear receptor binding agents |
| US8546451B2 (en) | 2005-11-28 | 2013-10-01 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US9409856B2 (en) | 2005-11-28 | 2016-08-09 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US8637706B2 (en) | 2005-11-28 | 2014-01-28 | Gtx, Inc. | Nuclear receptor binding agents |
| CA2677861C (en) * | 2007-02-14 | 2015-05-19 | Hormos Medical Ltd. | Method for the preparation of therapeutically valuable triphenylbutene derivatives |
| US7504530B2 (en) * | 2007-02-14 | 2009-03-17 | Hormos Medical Ltd. | Methods for the preparation of fispemifene from ospemifene |
| US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US9624161B2 (en) | 2009-02-23 | 2017-04-18 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| WO2014060639A1 (en) | 2012-10-19 | 2014-04-24 | Fermion Oy | A process for the preparation of ospemifene |
| CN103739456A (zh) * | 2013-12-03 | 2014-04-23 | 镇江圣安医药有限公司 | 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用 |
| GR1009542B (el) | 2018-04-25 | 2019-06-07 | Φαρματεν Α.Β.Ε.Ε. | Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων |
| PL3790548T3 (pl) | 2018-05-11 | 2024-03-11 | Xenon Pharmaceuticals Inc. | Sposoby zwiększania biodostępności i ekspozycji otwieracza kanałów potasowych bramkowanych napięciem |
| HUE070295T2 (hu) | 2019-10-10 | 2025-05-28 | Xenon Pharmaceuticals Inc | Szelektív kálium csatorna modulátor szilárd állapotú kristályos formái |
| EP4054580A1 (en) | 2019-11-08 | 2022-09-14 | Xenon Pharmaceuticals Inc. | Methods of treating depressive disorders |
| KR20240004241A (ko) | 2021-02-09 | 2024-01-11 | 제논 파마슈티칼스 인크. | 무쾌감증의 치료에 사용하기 위한 전압-게이트 칼륨 채널 오프너 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9007052D0 (en) * | 1990-03-29 | 1990-05-30 | Skua Investments Ltd | Pharmaceutical formulations |
| GB9207437D0 (en) | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| GB9418067D0 (en) * | 1994-09-07 | 1994-10-26 | Orion Yhtymae Oy | Triphenylethylenes for the prevention and treatment of osteoporosis |
| GB9604577D0 (en) | 1996-03-04 | 1996-05-01 | Orion Yhtymae Oy | Serum cholesterol lowering agent |
| WO2000008001A1 (en) * | 1998-08-07 | 2000-02-17 | Chiron Corporation | Substituted isoxazole as estrogen receptor modulators |
| US6219674B1 (en) | 1999-11-24 | 2001-04-17 | Classen Immunotherapies, Inc. | System for creating and managing proprietary product data |
| US6245819B1 (en) * | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
| US6653639B1 (en) * | 2000-10-17 | 2003-11-25 | Nikon Corporation | Chuck for mounting reticle to a reticle stage |
| CA2438816A1 (en) | 2001-02-22 | 2002-09-06 | Classen Immunotherapies, Inc. | Improved algorithms and methods for products safety |
| FR2826811B1 (fr) | 2001-06-27 | 2003-11-07 | France Telecom | Procede d'authentification cryptographique |
| UA79797C2 (en) | 2002-06-06 | 2007-07-25 | Hormos Medical Corp | Method for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women |
| US8236861B2 (en) | 2004-02-13 | 2012-08-07 | Hormos Medical Corporation | Method for enhancing the bioavailablity of ospemifene |
| US20050187302A1 (en) | 2004-02-23 | 2005-08-25 | Hormos Medical Corporation | Method for treatment or prevention of osteoporosis in individuals with high bone turnover |
| US8642079B2 (en) | 2004-02-23 | 2014-02-04 | Hormos Medical Corporation | Solid formulations of ospemifene |
| US8758821B2 (en) | 2004-05-04 | 2014-06-24 | Hormos Medical Ltd. | Oral formulations of ospemifene |
| US20060293294A1 (en) | 2004-09-03 | 2006-12-28 | Hormos Medical Corporation | Method for treatment or prevention of androgen deficiency |
| KR100665758B1 (ko) * | 2005-09-15 | 2007-01-09 | 제일모직주식회사 | 반사방지성을 갖는 하드마스크 조성물 |
-
2004
- 2004-02-13 US US10/777,211 patent/US8236861B2/en active Active
-
2005
- 2005-01-14 CA CA2556089A patent/CA2556089C/en not_active Expired - Lifetime
- 2005-01-14 AU AU2005211958A patent/AU2005211958B2/en not_active Ceased
- 2005-01-14 ES ES05701734T patent/ES2302177T3/es not_active Expired - Lifetime
- 2005-01-14 WO PCT/FI2005/000018 patent/WO2005077350A1/en active IP Right Grant
- 2005-01-14 BR BRPI0507661-7A patent/BRPI0507661A/pt not_active Application Discontinuation
- 2005-01-14 DE DE602005005165T patent/DE602005005165T2/de not_active Expired - Lifetime
- 2005-01-14 JP JP2006552639A patent/JP5577011B2/ja not_active Expired - Fee Related
- 2005-01-14 CN CNA200580004550XA patent/CN1925847A/zh active Pending
- 2005-01-14 EP EP05701734A patent/EP1713458B1/en not_active Expired - Lifetime
- 2005-01-14 RU RU2006132719/15A patent/RU2385716C2/ru active
- 2005-01-14 MX MXPA06009274A patent/MXPA06009274A/es active IP Right Grant
- 2005-01-14 AT AT05701734T patent/ATE387910T1/de active
- 2005-01-14 PL PL05701734T patent/PL1713458T3/pl unknown
- 2005-01-14 PT PT05701734T patent/PT1713458E/pt unknown
- 2005-01-14 DK DK05701734T patent/DK1713458T5/da active
-
2006
- 2006-09-05 NO NO20063960A patent/NO337656B1/no unknown
-
2008
- 2008-04-24 CY CY20081100456T patent/CY1111014T1/el unknown
-
2012
- 2012-07-06 US US13/543,166 patent/US8470890B2/en not_active Expired - Fee Related
-
2013
- 2013-05-29 US US13/904,818 patent/US8772353B2/en not_active Expired - Lifetime
-
2014
- 2014-05-12 JP JP2014098549A patent/JP6023119B2/ja not_active Expired - Fee Related
- 2014-06-20 US US14/310,822 patent/US9241915B2/en not_active Expired - Fee Related
-
2015
- 2015-06-10 LU LU92736C patent/LU92736I2/xx unknown
- 2015-06-10 BE BE2015C033C patent/BE2015C033I2/fr unknown
- 2015-06-11 FR FR15C0041C patent/FR15C0041I2/fr active Active
- 2015-06-16 HU HUS1500030C patent/HUS1500030I1/hu unknown
- 2015-06-25 LT LTPA2015023C patent/LTC1713458I2/lt unknown
- 2015-07-08 CY CY2015027C patent/CY2015027I1/el unknown
- 2015-11-25 NO NO20151603A patent/NO339190B1/no unknown
- 2015-12-16 US US14/971,252 patent/US9855224B2/en not_active Expired - Lifetime
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