CY1109428T1 - Μεθοδοι για το διαχωρισμο της μοδαφινιλης - Google Patents

Μεθοδοι για το διαχωρισμο της μοδαφινιλης

Info

Publication number
CY1109428T1
CY1109428T1 CY20091100213T CY091100213T CY1109428T1 CY 1109428 T1 CY1109428 T1 CY 1109428T1 CY 20091100213 T CY20091100213 T CY 20091100213T CY 091100213 T CY091100213 T CY 091100213T CY 1109428 T1 CY1109428 T1 CY 1109428T1
Authority
CY
Cyprus
Prior art keywords
methods
dividing
modafinil
isolation
directed
Prior art date
Application number
CY20091100213T
Other languages
English (en)
Inventor
Wilhelm Hauck
Olivier Ludemann-Hombourger
Y Ruland
Nelson Landmesser
John MALLAMO
Original Assignee
Cephalon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04292199A external-priority patent/EP1634861A1/en
Application filed by Cephalon, Inc. filed Critical Cephalon, Inc.
Publication of CY1109428T1 publication Critical patent/CY1109428T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Η παρούσα εφεύρεση είναι προσανατολισμένη σε μία μέθοδο για την απομόνωση εναντιομερών μορφών της μοδαφινίλης με υψηλή καθαρότητα εναντιομερούς και υψηλή συνολική απόδοση με τη βοήθεια μία συνεχούς χρωματογραφικής μεθόδου.
CY20091100213T 2004-09-13 2009-02-26 Μεθοδοι για το διαχωρισμο της μοδαφινιλης CY1109428T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP04292199A EP1634861A1 (en) 2004-09-13 2004-09-13 Methods for the separation of modafinil
US61151104P 2004-09-20 2004-09-20
US11/224,250 US20060086667A1 (en) 2004-09-13 2005-09-12 Methods for the separation of enantiomeric sulfinylacetamides
EP05782778A EP1797021B1 (en) 2004-09-13 2005-09-13 Methods for the separation of modafinil

Publications (1)

Publication Number Publication Date
CY1109428T1 true CY1109428T1 (el) 2014-08-13

Family

ID=35445665

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100213T CY1109428T1 (el) 2004-09-13 2009-02-26 Μεθοδοι για το διαχωρισμο της μοδαφινιλης

Country Status (17)

Country Link
US (1) US20060086667A1 (el)
EP (1) EP1797021B1 (el)
JP (1) JP4942656B2 (el)
CN (1) CN101014555B (el)
AT (1) ATE416152T1 (el)
CA (1) CA2575802C (el)
CY (1) CY1109428T1 (el)
DE (1) DE602005011463D1 (el)
DK (1) DK1797021T3 (el)
ES (1) ES2318527T3 (el)
HK (1) HK1100436A1 (el)
IL (1) IL181002A (el)
MX (1) MX2007002533A (el)
PL (1) PL1797021T3 (el)
PT (1) PT1797021E (el)
SI (1) SI1797021T1 (el)
WO (1) WO2006030278A1 (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1702915A1 (en) 2005-03-14 2006-09-20 Cephalon France Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation
US20100010092A1 (en) * 2006-12-19 2010-01-14 Arless Ltd. Use of modafinil to treat restless leg syndrome
WO2009025791A2 (en) * 2007-08-16 2009-02-26 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
BR112012016308B1 (pt) 2009-12-30 2020-03-31 Basf Pharma (Callanish) Limited Processo de separação cromatográfica para recuperar um produto de ácido graxo poli-insaturado (pufa) e composição
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
CN102502010A (zh) * 2011-10-20 2012-06-20 广东中烟工业有限责任公司梅州卷烟厂 用于减少封箱时胶带纸折叠的导向机构
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
CN103412062A (zh) * 2013-07-17 2013-11-27 张家港威胜生物医药有限公司 一种测定莫达非尼含量的高效液相色谱法
EP3118186B1 (fr) 2013-12-11 2022-02-09 Novasep Process Installation chromatographique de production d acides gras polyinsatures
BR112016015718B1 (pt) 2014-01-07 2021-12-07 Novasep Process Solutions Processo de purificação de aminoácidos aromáticos
US9127136B1 (en) * 2014-07-18 2015-09-08 Sabic Global Technologies B.V. Purification of monomer from recycle polyesters

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
JPH0730010B2 (ja) * 1986-02-26 1995-04-05 ダイセル化学工業株式会社 スルホキシドの光学分割方法
JPH07285889A (ja) * 1994-04-20 1995-10-31 Daicel Chem Ind Ltd 光学異性体の分離方法
JP3611343B2 (ja) * 1994-06-02 2005-01-19 ダイセル化学工業株式会社 擬似移動層式クロマト分離装置における光学異性体分離のモニター方法、擬似移動層式クロマト分離装置および擬似移動層式クロマト分離方法
JPH09206502A (ja) * 1995-12-01 1997-08-12 Daicel Chem Ind Ltd 擬似移動床式分離装置
US5630943A (en) * 1995-11-30 1997-05-20 Merck Patent Gesellschaft Mit Beschrankter Haftung Discontinuous countercurrent chromatographic process and apparatus
DE69913332T2 (de) * 1998-05-01 2004-05-27 Pfizer Products Inc., Groton Verfahren zur herstellung von enantiomeren reinem oder optisch angereicherter sertraline-tetralon durch kontinuierliche chromatographie
FR2785196B1 (fr) * 1998-10-29 2000-12-15 Inst Francais Du Petrole Procede et dispositif de separation avec des zones chromatographiques a longueur variable
US6413419B1 (en) * 1998-10-29 2002-07-02 Institut Francais Du Petrole Process and device for separation with variable-length chromatographic
US6375839B1 (en) * 1998-10-29 2002-04-23 Institut Francais Du Petrole Process and device for separation with variable-length chromatographic zones
DK1309547T3 (da) * 2000-07-27 2007-05-21 Teva Pharma Krystallinsk og ren modafinil og fremgangsmåde til fremstilling af samme
US7399409B2 (en) * 2000-10-13 2008-07-15 Daicel Chemical Industries, Ltd. Packing material for separation of optical isomer and method of separating optical isomer with the same
JP2004003935A (ja) * 2002-04-12 2004-01-08 Daicel Chem Ind Ltd 擬似移動床式クロマトグラフィー用光学異性体分離用充填剤
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
EP2159219A3 (en) * 2006-03-01 2010-12-15 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of armodafinil

Also Published As

Publication number Publication date
US20060086667A1 (en) 2006-04-27
EP1797021B1 (en) 2008-12-03
MX2007002533A (es) 2007-05-09
IL181002A (en) 2011-02-28
IL181002A0 (en) 2007-07-04
CN101014555A (zh) 2007-08-08
ES2318527T3 (es) 2009-05-01
ATE416152T1 (de) 2008-12-15
DE602005011463D1 (de) 2009-01-15
JP2008512437A (ja) 2008-04-24
SI1797021T1 (sl) 2009-04-30
CA2575802A1 (en) 2006-03-23
HK1100436A1 (en) 2007-09-21
JP4942656B2 (ja) 2012-05-30
CN101014555B (zh) 2010-12-08
EP1797021A1 (en) 2007-06-20
DK1797021T3 (da) 2009-02-09
CA2575802C (en) 2013-05-14
WO2006030278A1 (en) 2006-03-23
PL1797021T3 (pl) 2009-06-30
PT1797021E (pt) 2009-01-12

Similar Documents

Publication Publication Date Title
CY1109428T1 (el) Μεθοδοι για το διαχωρισμο της μοδαφινιλης
TR201901647T4 (tr) Saflaştırılmış ansamitosinlerin hazırlanmasına yönelik proses.
EA200900793A1 (ru) Способ получения эзетимиба и его производных
EA200601795A1 (ru) Синтез эфиров бороновой кислоты и кислотных соединений
WO2006027705A3 (en) Synthesis of triethylenetetramines
BRPI0515470A (pt) processos e intermediários para preparação de inibidores de cisteìna protease
NO20081686L (no) Fremgangsmate for fremstilling av esteroksazolidinforbindelser, og deres omdannelse til Florfnicol
HRP20080554A2 (en) Process for preparation of hiv protease inhibitors
TW201206878A (en) A method of producing ingenol-3-angelate
TW200728310A (en) Process for the preparation of ferri-succinylcasein
MY184725A (en) Process for the purification of biomass hydrolysate
MX2007010141A (es) Procesos para la preparacion de intermedios de linezolid.
CY1108156T1 (el) Στερεοεκλεκτικη συνθεση αναλογων βιταμινης d
CY1108121T1 (el) Διαδικασια παρασκευης ζ-φλουπεντιξολης
TN2012000542A1 (en) Agomelatine intermediates and preparation method thereof
IL184041A0 (en) Enzymatic transformation of a prostaglandin (bimatoprost) intermediate
DK2152667T3 (da) Fremgangsmåder til fremstilling af N-isobutyl-n-(2-hydroxy-3-amin-4-phenylbutyl)-p-nitrobenzenesulfonylamid-derivater
MY139521A (en) Stereoselective synthesis of vitamin d analogues
PH12021551008A1 (en) Purification method for vaccine virus using affinity chromatography
EA200800466A1 (ru) Способ получения эрбумина периндоприла
TW200728267A (en) Processes and intermediates for the preparation of prostaglandins
IN2014CH01392A (el)
MY161959A (en) Continuous production of high purity carbon dioxide
ATE494269T1 (de) Verbesserte methode zur kohlenwasserstoff- isomerisierung
EA200701105A1 (ru) Способ получения высоких уровней интерферона-бета