CY1108090T1 - Επαυξηση και αυξηση ογκου μαλακου ιστου και οστου χρησιμοποιωντας μυο-λαμβανομενα προγονα κυτταρα, συνθεσεις και θεραπειες αυτων - Google Patents
Επαυξηση και αυξηση ογκου μαλακου ιστου και οστου χρησιμοποιωντας μυο-λαμβανομενα προγονα κυτταρα, συνθεσεις και θεραπειες αυτωνInfo
- Publication number
- CY1108090T1 CY1108090T1 CY20071100849T CY071100849T CY1108090T1 CY 1108090 T1 CY1108090 T1 CY 1108090T1 CY 20071100849 T CY20071100849 T CY 20071100849T CY 071100849 T CY071100849 T CY 071100849T CY 1108090 T1 CY1108090 T1 CY 1108090T1
- Authority
- CY
- Cyprus
- Prior art keywords
- mdcs
- growth
- muscle
- soft tissue
- compositions
- Prior art date
Links
- 210000004872 soft tissue Anatomy 0.000 title abstract 4
- 238000011282 treatment Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 210000000988 bone and bone Anatomy 0.000 title 1
- 239000002537 cosmetic Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 210000002027 skeletal muscle Anatomy 0.000 abstract 2
- 208000008238 Muscle Spasticity Diseases 0.000 abstract 1
- 208000010428 Muscle Weakness Diseases 0.000 abstract 1
- 206010028289 Muscle atrophy Diseases 0.000 abstract 1
- 206010028372 Muscular weakness Diseases 0.000 abstract 1
- 208000000112 Myalgia Diseases 0.000 abstract 1
- 208000002033 Myoclonus Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000003416 augmentation Effects 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 230000036244 malformation Effects 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 230000020763 muscle atrophy Effects 0.000 abstract 1
- 201000000585 muscular atrophy Diseases 0.000 abstract 1
- 201000006938 muscular dystrophy Diseases 0.000 abstract 1
- 208000018198 spasticity Diseases 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
- C12N5/0659—Satellite cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Developmental Biology & Embryology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/549,937 US7115417B1 (en) | 1998-05-01 | 2000-04-14 | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
| EP01924998A EP1272204B1 (en) | 2000-04-14 | 2001-04-12 | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108090T1 true CY1108090T1 (el) | 2014-02-12 |
Family
ID=24195003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071100849T CY1108090T1 (el) | 2000-04-14 | 2007-06-28 | Επαυξηση και αυξηση ογκου μαλακου ιστου και οστου χρησιμοποιωντας μυο-λαμβανομενα προγονα κυτταρα, συνθεσεις και θεραπειες αυτων |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9499791B2 (OSRAM) |
| EP (1) | EP1272204B1 (OSRAM) |
| JP (2) | JP5684963B2 (OSRAM) |
| AT (1) | ATE365045T1 (OSRAM) |
| AU (2) | AU2001251599B2 (OSRAM) |
| CA (1) | CA2406393C (OSRAM) |
| CY (1) | CY1108090T1 (OSRAM) |
| DE (1) | DE60129007T2 (OSRAM) |
| DK (1) | DK1272204T3 (OSRAM) |
| ES (1) | ES2288946T3 (OSRAM) |
| HK (1) | HK1052645B (OSRAM) |
| PT (1) | PT1272204E (OSRAM) |
| WO (1) | WO2001078754A2 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6485723B1 (en) | 1995-02-10 | 2002-11-26 | Purdue Research Foundation | Enhanced submucosal tissue graft constructs |
| US6866842B1 (en) | 1998-05-01 | 2005-03-15 | University Of Pittsburgh | Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction |
| US7115417B1 (en) | 1998-05-01 | 2006-10-03 | Chancellor Michael B | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
| EP1272204B1 (en) | 2000-04-14 | 2007-06-20 | University of Pittsburgh | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof |
| CA2438904C (en) * | 2001-02-23 | 2012-09-04 | The University Of Pittsburgh | Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair |
| US20030082153A1 (en) * | 2001-10-22 | 2003-05-01 | The Government Of The United States Of America | Stem cells that transform to beating cardiomyocytes |
| EP1585426A4 (en) | 2002-05-02 | 2006-09-20 | Cook Biotech Inc | WITH CELLS VACCINATED EXTRACELLULAR MATRIX TRANSPLANTS |
| NZ536563A (en) | 2002-05-02 | 2008-03-28 | Purdue Research Foundation | Vascularization enhanced graft constructs |
| CA2483913C (en) | 2002-05-02 | 2014-07-15 | Purdue Research Foundation | Vascularization enhanced graft constructs comprising basement membrane |
| CA2483908C (en) | 2002-05-02 | 2012-02-21 | Purdue Research Foundation | Vascularization enhanced graft constructs |
| BR0311443A (pt) | 2002-05-06 | 2005-03-22 | Becton Dickinson Co | Método e dispositivo para controlar farmacocinética de droga |
| AU2003263906B2 (en) * | 2002-08-23 | 2009-10-29 | Peter K. Law | Biologic skin repair and enhancement |
| CN1812800B (zh) | 2003-04-25 | 2013-01-16 | 匹兹堡大学 | 用于促进和增强神经修复和再生的肌肉来源的细胞(mdc) |
| WO2005046746A2 (en) | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| WO2005070328A1 (en) | 2004-01-09 | 2005-08-04 | Regeneration Technologies, Inc. | Muscle-based grafts/implants |
| WO2005070439A1 (en) * | 2004-01-09 | 2005-08-04 | Regeneration Technologies Inc. | Implant comprising a human muscle tissue matrix |
| US7001430B2 (en) | 2004-01-09 | 2006-02-21 | Regeneration Technologies, Inc. | Matrix composition for human grafts/implants |
| ZA200710471B (en) * | 2005-05-30 | 2009-03-25 | Commw Scient Ind Res Org | Preparation and use of basement membrane particles |
| US20070065415A1 (en) * | 2005-09-16 | 2007-03-22 | Kleinsek Donald A | Compositions and methods for the augmentation and repair of defects in tissue |
| US7815923B2 (en) | 2005-12-29 | 2010-10-19 | Cook Biotech Incorporated | Implantable graft material |
| AU2007325698B2 (en) * | 2006-11-28 | 2014-03-20 | University Of Pittsburgh | Muscle derived cells for the treatment of cardiac pathologies and methods of making and using the same |
| JP5570814B2 (ja) * | 2006-12-18 | 2014-08-13 | ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | 胃食道病理学を処置するための筋由来細胞ならびにその作成法および使用法 |
| US20100158875A1 (en) | 2006-12-18 | 2010-06-24 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Muscle derived cells for the treatment of gastro-esophageal pathologies and methods of making and using the same |
| AU2008205278B2 (en) | 2007-01-11 | 2014-06-12 | University Of Pittsburgh | Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same |
| ATE554160T1 (de) * | 2007-05-29 | 2012-05-15 | Univ Pittsburgh | Knochenaufbau anhand von vorläuferzusammensetzungen aus muskeln und behandlungen damit |
| WO2009045506A2 (en) * | 2007-10-04 | 2009-04-09 | University Of Pittsburgh- | Skeletal muscle augmentation utilizing muscle-derived progenitor compositions, and treatments thereof |
| US9199003B2 (en) | 2008-08-18 | 2015-12-01 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof |
| US20130123647A1 (en) | 2011-05-03 | 2013-05-16 | The Research Foundation Of State University Of New York | Methods Useful in Optimizing the Treatment of Neuropathies and Targeting Tissues with Cosmetic Botulinum Injections |
| US9878071B2 (en) | 2013-10-16 | 2018-01-30 | Purdue Research Foundation | Collagen compositions and methods of use |
| EP4548939A3 (en) | 2014-08-27 | 2025-08-06 | Purdue Research Foundation | Collagen-based therapeutic delivery systems |
| WO2016172365A1 (en) | 2015-04-21 | 2016-10-27 | Purdue Research Foundation Office Of Technology Commercialization | Cell-collagen-silica composites and methods of making and using the same |
| CA3052266A1 (en) | 2017-01-31 | 2018-08-09 | Geniphys, Llc | Methods and compositions for matrix preparation |
| WO2018200750A1 (en) | 2017-04-25 | 2018-11-01 | Purdue Research Foundation | 3-dimensional (3d) tissue-engineered muscle for tissue restoration |
| SI3724319T1 (sl) | 2017-12-14 | 2023-07-31 | Innovacell Ag | Metode za pridobivanje mišičnih celic |
| BR112021016264A2 (pt) | 2019-03-22 | 2021-10-13 | Innovacell Ag | Métodos para obter células musculares lisas induzidas |
| EP3778875A1 (en) * | 2019-08-14 | 2021-02-17 | MaxiVax SA | Immortalized myoblast cell lines and uses thereof |
| WO2021154845A1 (en) | 2020-01-27 | 2021-08-05 | Geniphys, Llc | Biologic filler for restoring and regenerating tissue |
| CA3266771A1 (en) | 2022-09-02 | 2024-03-07 | Universitat Zurich | INJECTION DEVICE |
| EP4622706A1 (en) | 2022-11-21 | 2025-10-01 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | System for control of spasticity |
| WO2024115761A1 (en) | 2022-12-01 | 2024-06-06 | Universität Zürich | Method of preparing a mass culture of muscle precursor cells (mpcs) and uses thereof |
| JP2025041170A (ja) * | 2023-09-13 | 2025-03-26 | 昌毅 本田 | 肛門狭窄化治療法 |
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-
2001
- 2001-04-12 EP EP01924998A patent/EP1272204B1/en not_active Revoked
- 2001-04-12 AU AU2001251599A patent/AU2001251599B2/en not_active Expired
- 2001-04-12 CA CA2406393A patent/CA2406393C/en not_active Expired - Lifetime
- 2001-04-12 DK DK01924998T patent/DK1272204T3/da active
- 2001-04-12 HK HK03104760.7A patent/HK1052645B/en not_active IP Right Cessation
- 2001-04-12 ES ES01924998T patent/ES2288946T3/es not_active Expired - Lifetime
- 2001-04-12 PT PT01924998T patent/PT1272204E/pt unknown
- 2001-04-12 JP JP2001576054A patent/JP5684963B2/ja not_active Expired - Lifetime
- 2001-04-12 AT AT01924998T patent/ATE365045T1/de active
- 2001-04-12 AU AU5159901A patent/AU5159901A/xx active Pending
- 2001-04-12 WO PCT/US2001/012084 patent/WO2001078754A2/en not_active Ceased
- 2001-04-12 DE DE60129007T patent/DE60129007T2/de not_active Expired - Lifetime
-
2007
- 2007-06-28 CY CY20071100849T patent/CY1108090T1/el unknown
-
2008
- 2008-10-03 US US12/245,379 patent/US9499791B2/en active Active
-
2012
- 2012-04-19 JP JP2012095437A patent/JP2012180355A/ja not_active Withdrawn
-
2016
- 2016-11-09 US US15/347,308 patent/US20170209495A1/en not_active Abandoned
-
2020
- 2020-06-22 US US16/908,037 patent/US20210145892A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HK1052645B (en) | 2008-03-20 |
| DE60129007D1 (de) | 2007-08-02 |
| AU5159901A (en) | 2001-10-30 |
| AU2001251599B2 (en) | 2006-03-02 |
| JP5684963B2 (ja) | 2015-03-18 |
| DE60129007T2 (de) | 2008-02-28 |
| EP1272204A2 (en) | 2003-01-08 |
| US20210145892A1 (en) | 2021-05-20 |
| CA2406393C (en) | 2012-10-02 |
| JP2012180355A (ja) | 2012-09-20 |
| US20170209495A1 (en) | 2017-07-27 |
| WO2001078754A3 (en) | 2002-04-25 |
| HK1052645A1 (en) | 2003-09-26 |
| PT1272204E (pt) | 2007-10-02 |
| JP2003531125A (ja) | 2003-10-21 |
| US20090098094A1 (en) | 2009-04-16 |
| CA2406393A1 (en) | 2001-10-25 |
| ES2288946T3 (es) | 2008-02-01 |
| DK1272204T3 (da) | 2007-09-10 |
| EP1272204B1 (en) | 2007-06-20 |
| WO2001078754A2 (en) | 2001-10-25 |
| US9499791B2 (en) | 2016-11-22 |
| ATE365045T1 (de) | 2007-07-15 |
| US20160303169A9 (en) | 2016-10-20 |
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