CN1127343C - 治疗哺乳动物疾病的成肌细胞组合物 - Google Patents
治疗哺乳动物疾病的成肌细胞组合物 Download PDFInfo
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- CN1127343C CN1127343C CN95192528A CN95192528A CN1127343C CN 1127343 C CN1127343 C CN 1127343C CN 95192528 A CN95192528 A CN 95192528A CN 95192528 A CN95192528 A CN 95192528A CN 1127343 C CN1127343 C CN 1127343C
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- sarcoplast
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Cardiology (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims (6)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35494494A | 1994-12-13 | 1994-12-13 | |
US08/354,944 | 1994-12-13 | ||
US47737795A | 1995-06-07 | 1995-06-07 | |
US08/477,377 | 1995-06-07 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA031015883A Division CN1477190A (zh) | 1994-12-13 | 1995-12-13 | 控制细胞融合的方法和相关组合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1146712A CN1146712A (zh) | 1997-04-02 |
CN1127343C true CN1127343C (zh) | 2003-11-12 |
Family
ID=26998623
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA031015883A Pending CN1477190A (zh) | 1994-12-13 | 1995-12-13 | 控制细胞融合的方法和相关组合物 |
CN95192528A Expired - Fee Related CN1127343C (zh) | 1994-12-13 | 1995-12-13 | 治疗哺乳动物疾病的成肌细胞组合物 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA031015883A Pending CN1477190A (zh) | 1994-12-13 | 1995-12-13 | 控制细胞融合的方法和相关组合物 |
Country Status (7)
Country | Link |
---|---|
US (3) | US6261832B1 (zh) |
EP (2) | EP1407788A2 (zh) |
CN (2) | CN1477190A (zh) |
AU (1) | AU4597696A (zh) |
CA (1) | CA2183167A1 (zh) |
SG (3) | SG99846A1 (zh) |
WO (1) | WO1996018303A1 (zh) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5869041A (en) * | 1996-01-12 | 1999-02-09 | The Miriam Hospital | Delivery of bioactive compounds to an organism |
ES2247621T3 (es) | 1996-02-15 | 2006-03-01 | Biosense Webster, Inc. | Sonda de excavacion. |
CA2225185A1 (en) * | 1997-08-11 | 1999-02-11 | Peter K. Law | Myoblast transfer therapy for relieving pain and for treating behavioral and perceptive abnormalities |
DE69838526T2 (de) | 1998-02-05 | 2008-07-03 | Biosense Webster, Inc., Diamond Bar | Gerät zum Freisetzen eines Medikaments im Herzen |
US7115417B1 (en) | 1998-05-01 | 2006-10-03 | Chancellor Michael B | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof |
US6866842B1 (en) | 1998-05-01 | 2005-03-15 | University Of Pittsburgh | Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction |
ATE414524T1 (de) * | 1998-05-01 | 2008-12-15 | Univ Pittsburgh | Verwendung von myoblasten zur herstellung eines medikaments zur behandlung der stressbedingten harninkontinenz |
EP1200559A2 (en) | 1999-07-23 | 2002-05-02 | Diacrin, Inc. | Muscle cells and their use in cardiac repair |
US20030113301A1 (en) * | 1999-07-23 | 2003-06-19 | Albert Edge | Muscle cells and their use in cardiac repair |
DK1272204T3 (da) | 2000-04-14 | 2007-09-10 | Univ Pittsburgh | Forstærkning og bulking af blödt væv og knoglevæv under anvendelse af muskelafledte progenitorceller, præparater deraf og behandling dermed |
CN1474707A (zh) * | 2000-09-12 | 2004-02-11 | �˵á�K���� | 生肌细胞输送导管和方法 |
AU2007202290B2 (en) * | 2000-09-12 | 2011-11-03 | Law, Peter K | Myogenic cell transfer catheter and method |
EP1372398B1 (en) | 2001-02-23 | 2013-07-10 | The University of Pittsburgh | Rapid preparation of stem cell matrices for use in tissue and organ treatement and repair |
US6681773B2 (en) * | 2001-02-28 | 2004-01-27 | Chase Medical, Inc. | Kit and method for use during ventricular restoration |
US20020133227A1 (en) * | 2001-02-28 | 2002-09-19 | Gregory Murphy | Ventricular restoration patch apparatus and method of use |
US7485088B2 (en) | 2001-09-05 | 2009-02-03 | Chase Medical L.P. | Method and device for percutaneous surgical ventricular repair |
WO2003039344A2 (en) | 2001-11-08 | 2003-05-15 | The Regents Of The University Of California | Methods and compositions for correction of cardiac conduction disturbances |
AU2003220562A1 (en) * | 2002-04-01 | 2003-10-20 | Peter K. Law | Cellular transplantation for heart regeneration |
US20040106896A1 (en) * | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
WO2003095016A1 (en) * | 2002-05-08 | 2003-11-20 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
US6932804B2 (en) * | 2003-01-21 | 2005-08-23 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
EP1509252A4 (en) * | 2002-05-08 | 2006-08-16 | Univ California | METHOD AND COMPOSITIONS FOR CORRECTING HEART TRANSFER FAULTS |
US20040191225A1 (en) * | 2002-08-06 | 2004-09-30 | Dinsmore Jonathan H. | Injection system |
WO2004017972A1 (en) * | 2002-08-23 | 2004-03-04 | Law Peter K | Biologic skin repair and enhancement |
US7317950B2 (en) * | 2002-11-16 | 2008-01-08 | The Regents Of The University Of California | Cardiac stimulation system with delivery of conductive agent |
US7627373B2 (en) * | 2002-11-30 | 2009-12-01 | Cardiac Pacemakers, Inc. | Method and apparatus for cell and electrical therapy of living tissue |
US20040158289A1 (en) * | 2002-11-30 | 2004-08-12 | Girouard Steven D. | Method and apparatus for cell and electrical therapy of living tissue |
ATE482713T1 (de) | 2003-04-25 | 2010-10-15 | Univ Pittsburgh | Von muskeln stammende zellen (mdcs) zur förderung und verbesserung der nervenreparatur und - regeneration |
DE10339905B4 (de) * | 2003-08-29 | 2009-04-23 | Kist-Europe Forschungsgesellschaft Mbh | Implantierbarer Mikrozellprozessor zur Krankheitsbehandlung |
US7840263B2 (en) * | 2004-02-27 | 2010-11-23 | Cardiac Pacemakers, Inc. | Method and apparatus for device controlled gene expression |
CA2567578C (en) | 2004-06-01 | 2018-04-24 | In Motion Investment, Ltd. | In vitro techniques for obtaining stem cells from blood |
US7764995B2 (en) | 2004-06-07 | 2010-07-27 | Cardiac Pacemakers, Inc. | Method and apparatus to modulate cellular regeneration post myocardial infarct |
US7828711B2 (en) * | 2004-08-16 | 2010-11-09 | Cardiac Pacemakers, Inc. | Method and apparatus for modulating cellular growth and regeneration using ventricular assist device |
US7981065B2 (en) | 2004-12-20 | 2011-07-19 | Cardiac Pacemakers, Inc. | Lead electrode incorporating extracellular matrix |
US8060219B2 (en) * | 2004-12-20 | 2011-11-15 | Cardiac Pacemakers, Inc. | Epicardial patch including isolated extracellular matrix with pacing electrodes |
US20060180187A1 (en) * | 2005-02-14 | 2006-08-17 | Squeegit, Inc. | Window cleaning apparatus |
AU2006244639A1 (en) * | 2005-03-31 | 2006-11-16 | Mytogen, Inc. | Treatment for heart disease |
AU2006244197A1 (en) | 2005-05-09 | 2006-11-16 | Mytogen, Inc. | Cellular cardiomyoplasty as supportive therapy in patients with heart disease |
CN101558409A (zh) * | 2005-06-02 | 2009-10-14 | 夸拉塔贸易有限公司 | 自动化细胞治疗系统 |
TW200734462A (en) | 2006-03-08 | 2007-09-16 | In Motion Invest Ltd | Regulating stem cells |
CA2674795C (en) | 2007-01-11 | 2016-08-23 | University Of Pittsburgh | Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same |
FR2931485B1 (fr) * | 2008-05-23 | 2011-06-17 | Centre Nat Rech Scient | Vaccin antitumoral comprenant des cellules tumorales modifiees |
EP2328596B1 (en) | 2008-08-18 | 2019-03-06 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Bone augmentation utilizing muscle-derived progenitor compositions in biocompatible matrix, and treatments thereof |
US20100233138A1 (en) * | 2008-11-07 | 2010-09-16 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Vocal Cord Augmentation Utilizing Muscle-Derived Progenitor Compositions, and Treatments Thereof |
US20150050300A1 (en) | 2013-08-16 | 2015-02-19 | Peter K. Law | Disease prevention and alleviation by human myoblast transplantation |
US20170247660A1 (en) * | 2014-09-18 | 2017-08-31 | National Health Research Institutes | Progenitor cells, method for preparation thereof and uses thereof |
JP6890553B2 (ja) * | 2015-06-11 | 2021-06-18 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイThe Board Of Trustees Of The University Of Illinois | 筋ジストロフィーキメラ細胞および筋ジストロフィーの処置方法 |
GB2567377A (en) * | 2016-10-27 | 2019-04-10 | Law Peter | Compositions comprising myoblasts for tumor growth inhibition and prevention of cancer cell metastasis by implantation |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58170437A (ja) * | 1982-03-30 | 1983-10-07 | Yamazaki Nabisuko Kk | ポテトフレ−クを主原料としたスナツク菓子の製造方法 |
US4663292A (en) * | 1984-12-21 | 1987-05-05 | Wong Daniel T | High-voltage biological macromolecule transfer and cell fusion system |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51151384A (en) * | 1975-06-20 | 1976-12-25 | Olympus Optical Co Ltd | Process for cultivating organic tissue or cells automatically |
US4228243A (en) * | 1978-07-13 | 1980-10-14 | Toray Industries, Inc. | Cell culture propagation apparatus |
US4500544A (en) | 1981-09-10 | 1985-02-19 | Chugai Seiyaku Kabushiki Kaisha | Ascochlorin derivatives, and pharmaceutical composition containing the same |
US5130141A (en) * | 1988-05-24 | 1992-07-14 | Law Peter K | Compositions for and methods of treating muscle degeneration and weakness |
JP2993982B2 (ja) * | 1988-10-21 | 1999-12-27 | モレキユラー デヴアイシズ コーポレイシヨン | 生細胞に対する細胞作用剤の効果を検出するための方法及び装置 |
US5240854A (en) * | 1989-06-05 | 1993-08-31 | Berry Eric S | Continuous high-density cell culture system |
US5139481A (en) * | 1991-08-07 | 1992-08-18 | The General Hospital Corporation | Treatment for type II diabetes |
CA2102519A1 (en) * | 1992-03-04 | 1993-09-05 | Jon A. Wolff | Method of delivering therapeutic substances to the brain |
US5602301A (en) * | 1993-11-16 | 1997-02-11 | Indiana University Foundation | Non-human mammal having a graft and methods of delivering protein to myocardial tissue |
US5512480A (en) * | 1994-03-11 | 1996-04-30 | Baxter International Inc. | Flow-through bioreactor with grooves for cell retention |
US5919449A (en) * | 1995-05-30 | 1999-07-06 | Diacrin, Inc. | Porcine cardiomyocytes and their use in treatment of insufficient cardiac function |
-
1995
- 1995-12-13 CN CNA031015883A patent/CN1477190A/zh active Pending
- 1995-12-13 EP EP20040000891 patent/EP1407788A2/en active Pending
- 1995-12-13 WO PCT/US1995/016093 patent/WO1996018303A1/en not_active Application Discontinuation
- 1995-12-13 SG SG9801012A patent/SG99846A1/en unknown
- 1995-12-13 SG SG1997004642A patent/SG74036A1/en unknown
- 1995-12-13 SG SG9801014A patent/SG99279A1/en unknown
- 1995-12-13 CN CN95192528A patent/CN1127343C/zh not_active Expired - Fee Related
- 1995-12-13 AU AU45976/96A patent/AU4597696A/en not_active Abandoned
- 1995-12-13 EP EP95944088A patent/EP0743820A4/en not_active Withdrawn
- 1995-12-13 CA CA002183167A patent/CA2183167A1/en not_active Abandoned
-
1998
- 1998-01-09 US US09/005,035 patent/US6261832B1/en not_active Expired - Fee Related
- 1998-01-09 US US09/005,034 patent/US7341719B1/en not_active Expired - Lifetime
-
2001
- 2001-05-31 US US09/867,519 patent/US20020031501A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58170437A (ja) * | 1982-03-30 | 1983-10-07 | Yamazaki Nabisuko Kk | ポテトフレ−クを主原料としたスナツク菓子の製造方法 |
US4663292A (en) * | 1984-12-21 | 1987-05-05 | Wong Daniel T | High-voltage biological macromolecule transfer and cell fusion system |
Also Published As
Publication number | Publication date |
---|---|
EP1407788A2 (en) | 2004-04-14 |
CN1146712A (zh) | 1997-04-02 |
AU4597696A (en) | 1996-07-03 |
EP0743820A4 (en) | 1997-06-11 |
SG99846A1 (en) | 2003-11-27 |
EP0743820A1 (en) | 1996-11-27 |
SG74036A1 (en) | 2000-07-18 |
US6261832B1 (en) | 2001-07-17 |
US7341719B1 (en) | 2008-03-11 |
US20020031501A1 (en) | 2002-03-14 |
CN1477190A (zh) | 2004-02-25 |
SG99279A1 (en) | 2003-10-27 |
CA2183167A1 (en) | 1996-06-20 |
WO1996018303A1 (en) | 1996-06-20 |
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Owner name: WUHAN PENGLAI SARCOBLAST BIOENGINEERING RESEARCH I Free format text: FORMER OWNER: LAW PETER K. Effective date: 20110328 |
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