WO2004039832A3 - Leptin-related peptides - Google Patents

Leptin-related peptides Download PDF

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Publication number
WO2004039832A3
WO2004039832A3 PCT/US2003/034820 US0334820W WO2004039832A3 WO 2004039832 A3 WO2004039832 A3 WO 2004039832A3 US 0334820 W US0334820 W US 0334820W WO 2004039832 A3 WO2004039832 A3 WO 2004039832A3
Authority
WO
WIPO (PCT)
Prior art keywords
leptin
related peptides
weight
mass
novel
Prior art date
Application number
PCT/US2003/034820
Other languages
French (fr)
Other versions
WO2004039832A2 (en
Inventor
Patricia Grasso
Daniel W Lee
Matthew C Leinung
Maria Rozhavskaya-Arena
Original Assignee
Albany Medical College
Patricia Grasso
Daniel W Lee
Matthew C Leinung
Maria Rozhavskaya-Arena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albany Medical College, Patricia Grasso, Daniel W Lee, Matthew C Leinung, Maria Rozhavskaya-Arena filed Critical Albany Medical College
Priority to AU2003290563A priority Critical patent/AU2003290563A1/en
Publication of WO2004039832A2 publication Critical patent/WO2004039832A2/en
Publication of WO2004039832A3 publication Critical patent/WO2004039832A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissue mass.
PCT/US2003/034820 2002-10-31 2003-10-31 Leptin-related peptides WO2004039832A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003290563A AU2003290563A1 (en) 2002-10-31 2003-10-31 Leptin-related peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42272302P 2002-10-31 2002-10-31
US60/422,723 2002-10-31

Publications (2)

Publication Number Publication Date
WO2004039832A2 WO2004039832A2 (en) 2004-05-13
WO2004039832A3 true WO2004039832A3 (en) 2006-10-05

Family

ID=32230382

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/034820 WO2004039832A2 (en) 2002-10-31 2003-10-31 Leptin-related peptides

Country Status (2)

Country Link
AU (1) AU2003290563A1 (en)
WO (1) WO2004039832A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
CA2555877C (en) 2004-02-11 2015-11-24 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
US8263545B2 (en) 2005-02-11 2012-09-11 Amylin Pharmaceuticals, Inc. GIP analog and hybrid polypeptides with selectable properties
EP1853627A2 (en) 2005-02-11 2007-11-14 Amylin Pharmaceuticals, Inc. Gip analog and hybrid polypeptides with selectable properties
WO2007022123A2 (en) 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
EP2330125A3 (en) 2005-08-11 2012-12-12 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
US8497240B2 (en) 2006-08-17 2013-07-30 Amylin Pharmaceuticals, Llc DPP-IV resistant GIP hybrid polypeptides with selectable properties
GB2451858A (en) * 2007-08-15 2009-02-18 Sergiy Konovchuk Methods of reducing body fat and treating obesity
US8470772B2 (en) 2008-02-27 2013-06-25 Temple University—Of the Commonwealth System of Higher Education Leptin agonist and methods of use
US20120071401A1 (en) 2009-04-10 2012-03-22 Amylin Pharamaceuticals, Inc. Amylin agonist compounds for estrogen-deficient mammals
WO2011002673A1 (en) 2009-07-01 2011-01-06 Temple University - Of The Commonwealth System Of Higher Education Leptin agonist and methods of use
CN103403019B (en) 2010-09-28 2016-10-12 埃格里昂制药股份有限公司 There is the engineered polypeptide of the acting duration of enhancing
EP2729160B1 (en) 2011-07-08 2019-03-27 Aegerion Pharmaceuticals, Inc. Engineered polypeptides having enhanced duration of action and reduced immunogenicity
DK2900230T3 (en) 2012-09-27 2018-11-12 Childrens Medical Ct Corp RELATIONSHIPS FOR TREATING ADIPOSITAS AND PROCEDURES FOR USING THEREOF
US20160375039A1 (en) 2013-11-26 2016-12-29 The Children's Medical Center Corporation Compounds for the treatment of obesity and methods of use thereof
WO2015153933A1 (en) 2014-04-03 2015-10-08 The Children's Medical Center Corporation Hsp90 inhibitors for the treatment of obesity and methods of use thereof
JP7139317B2 (en) 2016-09-12 2022-09-20 アムリット・ファーマシューティカルズ・インコーポレイテッド Method for detecting anti-leptin neutralizing antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069900A2 (en) * 1999-05-17 2000-11-23 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
WO2002069232A2 (en) * 2001-02-19 2002-09-06 Merck Patent Gmbh Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069900A2 (en) * 1999-05-17 2000-11-23 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
WO2002069232A2 (en) * 2001-02-19 2002-09-06 Merck Patent Gmbh Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity

Also Published As

Publication number Publication date
AU2003290563A1 (en) 2004-05-25
AU2003290563A8 (en) 2004-05-25
WO2004039832A2 (en) 2004-05-13

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