CY1105263T1 - Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια - Google Patents

Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια

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Publication number
CY1105263T1
CY1105263T1 CY20061100219T CY061100219T CY1105263T1 CY 1105263 T1 CY1105263 T1 CY 1105263T1 CY 20061100219 T CY20061100219 T CY 20061100219T CY 061100219 T CY061100219 T CY 061100219T CY 1105263 T1 CY1105263 T1 CY 1105263T1
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CY
Cyprus
Prior art keywords
cop
nervous system
polypeptide
related peptide
polypeptides
Prior art date
Application number
CY20061100219T
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English (en)
Inventor
Michal Eisenbach-Schwartz
Eti Yoles
Jonathan Kipnis
Original Assignee
Yeda Research And Development Company, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Yeda Research And Development Company, Ltd. filed Critical Yeda Research And Development Company, Ltd.
Publication of CY1105263T1 publication Critical patent/CY1105263T1/el

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61K2239/47—Brain; Nervous system

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Abstract

Παρέχονται μέθοδοι για θεραπευτική αγωγή κάκωσης ή νόσου του κεντρικού ή περιφερικού νευρικού συστήματος. Σε μία υλοποίηση, η θεραπευτική αγωγή πραγματοποιείται χορηγώντας ενεργοποιημένα Τ-λεμφοκύτταρα που αναγνωρίζουν αντιγόνο Cop 1 ή πεπτίδιο ή πολυπεπτίδιο συναφές του Cop 1 για την προαγωγή αναγέννησης νεύρων ή αποτροπή ή αναστολή νευρωνικού εκφυλισμού στο νευρικό σύστημα. Σε άλλη υλοποίηση, η θεραπευτική αγωγή ενέχει χορήγηση Cop 1 ή πεπτιδίου ή πολυπεπτιδίου συναφούς του Cop 1 για προαγωγή αναγέννησης νεύρων ή για αποτροπή ή αναστολή νευρωνικού εκφυλισμού στο νευρικό σύστημα, είτε στο κεντρικό νευρικό σύστημα ή στο περιφερικό νευρικό σύστημα. Τα ενεργοποιημένα Τ-λεμφοκύτταρα, που έχουν ενεργοποιηθεί με την παρουσία Cop 1 ή πεπτιδίου ή πολυπεπτιδίου συναφούς του Cop 1, μπορούν να χορηγηθούν από μόνα τους ή σε συνδυασμό με Cop 1 ή με πεπτίδιο ή πολυπεπτίδιο συναφές του Cop 1.
CY20061100219T 2000-06-07 2006-02-16 Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια CY1105263T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20979900P 2000-06-07 2000-06-07
US62021600A 2000-07-20 2000-07-20
PCT/US2001/002118 WO2001093893A2 (en) 2000-06-07 2001-01-22 The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy

Publications (1)

Publication Number Publication Date
CY1105263T1 true CY1105263T1 (el) 2010-03-03

Family

ID=26904524

Family Applications (1)

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CY20061100219T CY1105263T1 (el) 2000-06-07 2006-02-16 Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια

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Country Link
US (1) US20020037848A1 (el)
EP (1) EP1294390B1 (el)
JP (1) JP4328090B2 (el)
KR (1) KR20030007397A (el)
CN (1) CN100438906C (el)
AT (1) ATE314860T1 (el)
AU (1) AU783031B2 (el)
CA (1) CA2398277C (el)
CY (1) CY1105263T1 (el)
DE (1) DE60116467T2 (el)
DK (1) DK1294390T3 (el)
ES (1) ES2256200T3 (el)
HK (1) HK1058892A1 (el)
IL (2) IL150801A0 (el)
MX (1) MXPA02007109A (el)
NZ (1) NZ520282A (el)
WO (1) WO2001093893A2 (el)

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JP5916622B2 (ja) * 2010-01-04 2016-05-11 マピ ファーマ リミテッド グラチラマーまたはその薬理学的に許容される塩を含むデポーシステム
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KR20140019296A (ko) 2010-10-11 2014-02-14 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응의 예측성 바이오마커로서의 사이토카인 바이오마커
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Publication number Publication date
CN100438906C (zh) 2008-12-03
ES2256200T3 (es) 2006-07-16
JP4328090B2 (ja) 2009-09-09
HK1058892A1 (en) 2004-06-11
WO2001093893A3 (en) 2002-04-04
WO2001093893A2 (en) 2001-12-13
NZ520282A (en) 2004-09-24
KR20030007397A (ko) 2003-01-23
CA2398277A1 (en) 2001-12-13
JP2004507460A (ja) 2004-03-11
DK1294390T3 (da) 2006-04-03
DE60116467T2 (de) 2006-11-02
MXPA02007109A (es) 2002-12-13
AU783031B2 (en) 2005-09-15
EP1294390B1 (en) 2006-01-04
AU3451801A (en) 2001-12-17
IL150801A (en) 2007-10-31
IL150801A0 (en) 2003-02-12
CN1462190A (zh) 2003-12-17
EP1294390A2 (en) 2003-03-26
ATE314860T1 (de) 2006-02-15
CA2398277C (en) 2013-09-03
US20020037848A1 (en) 2002-03-28
DE60116467D1 (de) 2006-03-30

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