CY1105263T1 - Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια - Google Patents

Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια

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Publication number
CY1105263T1
CY1105263T1 CY20061100219T CY061100219T CY1105263T1 CY 1105263 T1 CY1105263 T1 CY 1105263T1 CY 20061100219 T CY20061100219 T CY 20061100219T CY 061100219 T CY061100219 T CY 061100219T CY 1105263 T1 CY1105263 T1 CY 1105263T1
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Cyprus
Prior art keywords
cop
nervous system
polypeptide
related peptide
polypeptides
Prior art date
Application number
CY20061100219T
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English (en)
Inventor
Michal Eisenbach-Schwartz
Eti Yoles
Jonathan Kipnis
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Yeda Research And Development Company, Ltd.
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Publication date
Application filed by Yeda Research And Development Company, Ltd. filed Critical Yeda Research And Development Company, Ltd.
Publication of CY1105263T1 publication Critical patent/CY1105263T1/el

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46432—Nervous system antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/47—Brain; Nervous system

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Abstract

Παρέχονται μέθοδοι για θεραπευτική αγωγή κάκωσης ή νόσου του κεντρικού ή περιφερικού νευρικού συστήματος. Σε μία υλοποίηση, η θεραπευτική αγωγή πραγματοποιείται χορηγώντας ενεργοποιημένα Τ-λεμφοκύτταρα που αναγνωρίζουν αντιγόνο Cop 1 ή πεπτίδιο ή πολυπεπτίδιο συναφές του Cop 1 για την προαγωγή αναγέννησης νεύρων ή αποτροπή ή αναστολή νευρωνικού εκφυλισμού στο νευρικό σύστημα. Σε άλλη υλοποίηση, η θεραπευτική αγωγή ενέχει χορήγηση Cop 1 ή πεπτιδίου ή πολυπεπτιδίου συναφούς του Cop 1 για προαγωγή αναγέννησης νεύρων ή για αποτροπή ή αναστολή νευρωνικού εκφυλισμού στο νευρικό σύστημα, είτε στο κεντρικό νευρικό σύστημα ή στο περιφερικό νευρικό σύστημα. Τα ενεργοποιημένα Τ-λεμφοκύτταρα, που έχουν ενεργοποιηθεί με την παρουσία Cop 1 ή πεπτιδίου ή πολυπεπτιδίου συναφούς του Cop 1, μπορούν να χορηγηθούν από μόνα τους ή σε συνδυασμό με Cop 1 ή με πεπτίδιο ή πολυπεπτίδιο συναφές του Cop 1.
CY20061100219T 2000-06-07 2006-02-16 Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια CY1105263T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20979900P 2000-06-07 2000-06-07
US62021600A 2000-07-20 2000-07-20
PCT/US2001/002118 WO2001093893A2 (en) 2000-06-07 2001-01-22 The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy

Publications (1)

Publication Number Publication Date
CY1105263T1 true CY1105263T1 (el) 2010-03-03

Family

ID=26904524

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100219T CY1105263T1 (el) 2000-06-07 2006-02-16 Χρηση συμπολυμepους (copolymer) 1 και συναφων πεπτιδιων και πολυπεπτιδιων και t-λεμφοκυτταρων που εχουν υποβληθει σε αγωγη με αυτα για νευροπροστατευτικη θepαπεια

Country Status (17)

Country Link
US (1) US20020037848A1 (el)
EP (1) EP1294390B1 (el)
JP (1) JP4328090B2 (el)
KR (1) KR20030007397A (el)
CN (1) CN100438906C (el)
AT (1) ATE314860T1 (el)
AU (1) AU783031B2 (el)
CA (1) CA2398277C (el)
CY (1) CY1105263T1 (el)
DE (1) DE60116467T2 (el)
DK (1) DK1294390T3 (el)
ES (1) ES2256200T3 (el)
HK (1) HK1058892A1 (el)
IL (2) IL150801A0 (el)
MX (1) MXPA02007109A (el)
NZ (1) NZ520282A (el)
WO (1) WO2001093893A2 (el)

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US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
WO2001093828A1 (en) * 2000-06-05 2001-12-13 Teva Pharmaceuticals Industries, Ltd. The use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
DE60237170D1 (de) * 2001-12-04 2010-09-09 Teva Pharma Verfahren zur messung der wirkstärke von glatirameracetat
ES2322566T3 (es) * 2001-12-06 2009-06-23 Yeda Research And Development Co., Ltd. Vacuna y uso de la misma para el tratamiento de la esclerosis lateral amiotrofica.
CA2512735C (en) * 2003-01-07 2016-03-08 Yeda Research And Development Co. Ltd. Eye-drop vaccine containing copolymer 1 for therapeutic immunization
JP4632953B2 (ja) * 2003-09-29 2011-02-16 中外製薬株式会社 Ｎｋ細胞に発現するタンパク質
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US8759302B2 (en) * 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
JP2013541010A (ja) 2010-10-11 2013-11-07 テバ ファーマシューティカル インダストリーズ リミティド グラチラマーアセテートに対する臨床的な反応の予測可能なバイオマーカーとしてのサイトカインバイオマーカー
ES2601892T3 (es) 2011-04-21 2017-02-16 Mapi Pharma Limited Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
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Publication number Publication date
MXPA02007109A (es) 2002-12-13
DE60116467T2 (de) 2006-11-02
JP2004507460A (ja) 2004-03-11
HK1058892A1 (en) 2004-06-11
KR20030007397A (ko) 2003-01-23
DE60116467D1 (de) 2006-03-30
ATE314860T1 (de) 2006-02-15
US20020037848A1 (en) 2002-03-28
WO2001093893A3 (en) 2002-04-04
IL150801A0 (en) 2003-02-12
AU3451801A (en) 2001-12-17
CN100438906C (zh) 2008-12-03
ES2256200T3 (es) 2006-07-16
WO2001093893A2 (en) 2001-12-13
JP4328090B2 (ja) 2009-09-09
NZ520282A (en) 2004-09-24
CA2398277A1 (en) 2001-12-13
DK1294390T3 (da) 2006-04-03
IL150801A (en) 2007-10-31
EP1294390A2 (en) 2003-03-26
EP1294390B1 (en) 2006-01-04
AU783031B2 (en) 2005-09-15
CA2398277C (en) 2013-09-03
CN1462190A (zh) 2003-12-17

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